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(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide is a linker widely used in antibody-drug conjugates (ADCs). Group: Pharmaceutical. Alternative Names: (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide. CAS No. 1797406-69-9. Pack Sizes: 10 mg. Product ID: BADC-01565. Molecular formula: C49H60ClN9O8S2. Mole weight: 1002.64. Custom synthesis is available. Send your inquiries for more information.
N'-[(6-Methyl-2-pyridyl)methylene]pyrrolidine-1-carbothiohydrazide, a chemical entity with an aptitude for disrupting tumor metastasis, has recently proven to be quite efficacious. Its ability to suppress the growth of various cancerous cells has been demonstrated in numerous studies. When used judiciously, this agent could be quite promising in the treatment of cancer, opening up alternate therapeutic avenues. Group: Pharmaceutical. Alternative Names: 1-Pyrrolidinecarbothioic acid, [(6-methyl-2-pyridinyl)methylene]hydrazide; N'-[(6-Methyl-2-pyridinyl)methylene]-1-pyrrolidinecarbothiohydrazide. CAS No. 907549-72-8. Pack Sizes: 10 mg. Product ID: B0001-284865. Molecular formula: C12H16N4S. Mole weight: 248.35. Custom synthesis is available. Send your inquiries for more information.
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(N-Trimethylsilyl)pyrrolidine
(N-Trimethylsilyl)pyrrolidine Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 15097-49-1. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
(R)-2-[[(tert-Butyldimethylsilyl)oxy]diphenylmethyl]pyrrolidine (CAS# 1236033-34-3 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: tert-butyl-[diphenyl-[(2R)-2-pyrrolidinyl]methoxy]-dimethylsilane; tert-butyl-[diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-dimethylsilane. CAS No. 1236033-34-3. Pack Sizes: 500 mg. Product ID: BB005729. Molecular formula: C23H33NOSi. Mole weight: 367.6. Custom synthesis is available. Send your inquiries for more information.
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(S)-3-(Dimethylamino)pyrrolidine
(S)-3-(Dimethylamino)pyrrolidine is a useful research chemical. Group: Pharmaceutical. Alternative Names: (3S)-N,N-dimethyl-3-pyrrolidinamine; (3S)-(-)-3-(Dimethylamino)pyrrolidine; (S)-(-)-3-(Dimethylamino)pyrrolidine. CAS No. 132883-44-4. Pack Sizes: 25 g. Product ID: BB007649. Molecular formula: C6H14N2. Mole weight: 114.19. Custom synthesis is available. Send your inquiries for more information.
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1-Pyrenebutyric acid N-hydroxysuccinimide ester
1-Pyrenebutyric acid N-hydroxysuccinimide ester is a fluorescent probe for protein conjungation. Group: Pharmaceutical. Alternative Names: Pyrenebutyric acid NHS ester;2,5-Pyrrolidinedione, 1-(1-oxo-4-(1-pyrenyl)butoxy)-; 1-Succinimidyl-3'-pyrenebutyrate; 1-Pyrenebutanoic Acid Succinimidyl Ester. CAS No. 114932-60-4. Pack Sizes: 5 g. Product ID: B0245-352081. Molecular formula: C24H19NO4. Mole weight: 385.419. Custom synthesis is available. Send your inquiries for more information.
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2-(2-oxopyrrolidin-1-yl)butanoic Acid
An impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Group: Pharmaceutical. Alternative Names: alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid; (2RS)-2-(2-Oxopyrrolidin-1-yl)butanoic acid. CAS No. 67118-31-4. Pack Sizes: 250 mg. Product ID: B2694-074869. Molecular formula: C8H13NO3. Mole weight: 171.2. Custom synthesis is available. Send your inquiries for more information.
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2,5-Dioxopyrrolidin-1-yl 3-(tritylthio)propanoate
2,5-Dioxopyrrolidin-1-yl 3-(tritylthio)propanoate, a multifaceted chemical compound, plays a pivotal role in drug synthesis, specifically in the development of angiotensin converting enzyme inhibitors. In addition to its significance in this domain, it functions as a valuable building block in drug development for maladies such as hypertension, heart failure, and diabetes. Its diverse utilization and multifarious potential thereby make it a crucial focus of drug research. Group: Pharmaceutical. Alternative Names: 1-[1-oxo-3-[(triphenylmethyl)thio]propoxy]-2,5-Pyrrolidinedione; Mpa(Trt)-Osu. CAS No. 129431-12-5. Pack Sizes: 1 g. Product ID: B0001-286444. Molecular formula: C26H23NO4S. Mole weight: 445.533. Custom synthesis is available. Send your inquiries for more information.
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(2R)-Vildagliptin
(2R)-Vildagliptin is an R-enantiomer of Vildagliptin, which is a dipeptidyl peptidase-4 (DPP-4) inhibitor used as an anti-hyperglycemic agent and an anti-diabetic drug. Group: Pharmaceutical. Alternative Names: Vildagliptin Related Compound A; (2R)-1-[2-[[(5S,7R)-3-hydroxy-1-adamantyl]amino]acetyl]pyrrolidine-2-carbonitrile. CAS No. 1036959-27-9. Pack Sizes: 20 mg. Product ID: B0020-461928. Molecular formula: C17H25N3O2. Mole weight: 303.406. Custom synthesis is available. Send your inquiries for more information.
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7-Epi Clindamycin
7-Epi Clindamycin, a highly efficacious antibiotic, exhibits remarkable efficacy against a wide range of bacterial infections. By discerningly impeding protein synthesis within bacterial organisms, it disrupts their growth and obstructs their survival, effectively eliminating the pernicious microorganisms. Distinctively versatile, this compound demonstrates its unwavering effectiveness against both Gram-positive and Gram-negative bacteria. Consequently, this invaluable asset plays an integral role in the biomedical field, diligently combatting infectious ailments with exceptional efficacy. Group: Pharmaceutical. Alternative Names: D-erythro-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-α-; D-erythro-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-; Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; 7-Epiclindamycin; Antibiotic U 21251F. CAS No. 16684-06-3. Pack Sizes: 5 mg. Product ID: B1370-159244. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98. Custom synthesis is available. Send your inquiries for more information.
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7-Epi Lincomycin Hydrochloride Salt
7-Epi Lincomycin Hydrochloride Salt is an epimer of Lincomycin, a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. It is less potent bactericidal than its (7R)-epimer. Group: Pharmaceutical. Alternative Names: Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1- thio-L-threo-α-D-galacto-octopyranoside Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)- 1-thio-L-threo-D-galacto-octopyranoside. CAS No. 26389-84-4. Pack Sizes: 5 mg. Product ID: B2694-472409. Molecular formula: C18H35ClN2O6S. Mole weight: 443. Custom synthesis is available. Send your inquiries for more information.
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A 127722
A 127722 is a potent and selective ETA endothelin receptor antagonist (IC50 = 0.11 nM and 98 nM for human ETA and ETB receptors, respectively). It attenuates hypoxia-induced pulmonary hypertension in rats. Group: Pharmaceutical. Alternative Names: A-127722; A127722; rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid. CAS No. 195704-72-4. Pack Sizes: 1mg;1g;10g. Product ID: 195704-72-4. Molecular formula: C29H38N2O6. Mole weight: 510.62. Custom synthesis is available. Send your inquiries for more information.
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A-192621
A-192621 is a selective antagonist at endothelin ETB receptor with more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmented constrictor responses to ET-1. Group: Pharmaceutical. Alternative Names: (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-(4-propoxyphenyl)pyrrolidine-3-carboxylic acid; (2R-(2alpha,3beta,4alpha)-4-(1,3-benzodioxol-5-yl)-1-(2-(2,6-diethylphenyl)amino)-2-oxoethyl)-2-(4-propoxyphenyl)-3-pyrrolidinecarboxylic acid; A 192621; A-192621; A192621. CAS No. 195529-54-5. Pack Sizes: 1mg;1g;10g. Product ID: 195529-54-5. Molecular formula: C33H38N2O6. Mole weight: 558.675. Custom synthesis is available. Send your inquiries for more information.
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A-988056
A-988056. Group: Pharmaceutical. Alternative Names: (NZ,3R)-3-fluoro-N-[5-(hydroxymethyl)-3-(2,2,3,3-tetrafluoro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-ylidene]pyrrolidine-1-carboxamide; UNII-P4P3H8I844; A-988056; SCHEMBL3001634; P4P3H8I844; 1-Pyrrolidinecarboxamide,3-fluoro-N-(5-(hydroxymethyl)-3-(2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin-6-yl)-2(3H)-thiazolylidene)-,(N(Z),3S)-. CAS No. 1000859-51-7. Pack Sizes: 1mg;1g;10g. Product ID: 1000859-51-7. Molecular formula: C17H14F5N3O4S. Mole weight: 451.367776. Custom synthesis is available. Send your inquiries for more information.
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ABT-546
ABT-546 is a potent, highly selective and active antagonist of ETA receptor with a Ki of 0.46 nM for [125I]endothelin-1 binding to cloned human ETA. It is >25,000-fold more selectivity for ETA receptor than ETB receptor. It blocks endothelin-1-induced arachidonic acid release and phosphatidylinositol hydrolysis with IC50s of 0.59 and 3 nM, respectively. Group: Pharmaceutical. Alternative Names: A-216546 free base; 3-Pyrrolidinecarboxylic acid, 1-(2-(dibutylamino)-2-oxoethyl)-2-(2,2-dimethylpentyl)-4-(7-methoxy-1,3-benzodioxol-5-yl)-, (2S,3R,4S)-; (2S,3R,4S)-1-[2-(Dibutylamino)-2-oxoethyl]-2-(2,2-dimethylpentyl)-4-(7-methoxy-1,3-benzodioxol-5-yl)-3-pyrrolidinecarboxylic acid. CAS No. 212481-66-8. Pack Sizes: 1mg;1g;10g. Product ID: 212481-66-8. Molecular formula: C30H48N2O6. Mole weight: 532.71. Custom synthesis is available. Send your inquiries for more information.
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Apimostinel
Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Group: Pharmaceutical. Alternative Names: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel;(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. CAS No. 1421866-48-9. Pack Sizes: 5 mg. Product ID: B2693-475419. Molecular formula: C25H37N5O6. Mole weight: 503.6. Custom synthesis is available. Send your inquiries for more information.
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ARV-771
ARV-771 is a potent BET bromodomain PROTAC® Degrader based on von Hippel-Lindau (VHL) E3 ligase, consisting of a BRD4-binding moiety bound to a VHL ligand via a linker. Group: Pharmaceutical. Alternative Names: ARV 771; ARV771; (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide; L-Prolinamide, N-[2-[3-[2-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]amino]ethoxy]propoxy]acetyl]-3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-; N-({3-[2-({[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl}amino)ethoxy]propoxy}acetyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-{(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl}-L-prolinamide. CAS No. 1949837-12-0. Pack Sizes: 5 mg. Product ID: B2693-007297. Molecular formula: C49H60ClN9O7S2. Mole weight: 986.64. Custom synthesis is available. Send your inquiries for more information.
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Auristatin F
Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. CAS No. 163768-50-1. Pack Sizes: 25 mg. Product ID: BBF-05829. Molecular formula: C40H67N5O8. Mole weight: 745.99. Custom synthesis is available. Send your inquiries for more information.
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Azido-PEG2-NHS ester
Azido-PEG2-NHS ester is a non-cleavable 2-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Group: Pharmaceutical. Alternative Names: Azido-PEG2-CH2CO2-NHS; N3-PEG2-C2-NHS ester; Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; N3-PEG2-CH2CH2COONHS Ester; Azido-PEG2-NHS; N3-PEG2-SPA; 1-({3-[2-(2-Azidoethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[3-[2-(2-azidoethoxy)ethoxy]-1-oxopropoxy]-; 2,5-Dioxo-1-pyrrolidinyl 3-[2-(2-azidoethoxy)ethoxy]propanoate; N-Succinimido 9-azido-4,7-dioxanonanoate. CAS No. 1312309-64-0. Pack Sizes: 500 mg. Product ID: BADC-00409. Molecular formula: C11H16N4O6. Mole weight: 300.27. Custom synthesis is available. Send your inquiries for more information.
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Belnacasan
Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan inhibits interlukin-1β biosynthesis. Group: Pharmaceutical. Alternative Names: VX 765, VX765, VX-765, Belnacasan; (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide. CAS No. 273404-37-8. Pack Sizes: 50 mg. Product ID: B0084-307700. Molecular formula: C24H33ClN4O6. Mole weight: 509. Custom synthesis is available. Send your inquiries for more information.
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Bis-PEG1-NHS ester
Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Group: Pharmaceutical. Alternative Names: Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-oxydipropionate; Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-oxydipropanoate; 2,5-Pyrrolidinedione, 1,1'-[oxybis[(1-oxo-3,1-propanediyl)oxy]]bis-; Di-NHS Ester-PEG1; 1,1'-{Oxybis[(1-oxo-3,1-propanediyl)oxy]}di(2,5-pyrrolidinedione). CAS No. 65869-64-9. Pack Sizes: 100 mg. Product ID: BADC-00382. Molecular formula: C14H16N2O9. Mole weight: 356.28. Custom synthesis is available. Send your inquiries for more information.
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Clindamycin 2-Phosphate
Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat protozoal diseases, such as malaria. It is a common drug used to treat topical acne and can be effective against some methicillin-resistant Staphylococcus aureus (MRSA) infections. An impurity of Clindamycin. Group: Pharmaceutical. Alternative Names: Methyl 7-Chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidine-carboxamido)-1-thio-L-threo-α-D-galactooctopyranoside 2-(Dihydrogen Phosphate); 7(S)-Chloro-7-deoxylincomycin 2-Phosphate; Cleocin T; Cleocin Phosphate; Clinadac; Clindagel; Clindesse; Clindets; Dalacin P; Dalacin T; NSC 618653. CAS No. 24729-96-2. Pack Sizes: 100 g. Product ID: BBF-04542. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. Custom synthesis is available. Send your inquiries for more information.
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Dermorphin
Dermorphin, a naturally occurring heptapeptide originally found in the skin of amphibians, is a μ-opioid receptor(MOR) agonist with analgesic and antinociceptive effects. Group: Pharmaceutical. Alternative Names: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2; L-tyrosyl-D-alanyl-L-phenylalanyl-glycyl-L-tyrosyl-L-prolyl-L-serinamide; (S)-N-((S)-1-amino-3-hydroxy-1-oxopropan-2-yl)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-2-(4-hydroxybenzyl)-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamide. CAS No. 77614-16-5. Pack Sizes: 10 mg. Product ID: BAT-006192. Molecular formula: C40H50N8O10. Mole weight: 802.87. Custom synthesis is available. Send your inquiries for more information.
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Diclofenac epolamine
Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic effects. Group: Pharmaceutical. Alternative Names: DHEP; DIEP; Diclofenac hydroxyethylpyrrolidine; Flector; UNII-X5F8EKL9ZG; X5F8EKL9ZG; Diclofenac-N-(2-hydroxyethyl) pyrrolidine. CAS No. 119623-66-4. Pack Sizes: 1 g. Product ID: B2692-055485. Molecular formula: C20H24Cl2N2O3. Mole weight: 411.32. Custom synthesis is available. Send your inquiries for more information.
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Diprotin A
It is produced by the strain of Bacillus cereus BMF 657-RF1. It can inhibit Dipeptidyl amino peptidase IV and immune enhancement effect. Group: Pharmaceutical. Alternative Names: Ile-Pro-Ile; isoleucylprolylisoleucine; l-isoleucyl-l-prolyl-l-isoleucine; N-(1-L-Isoleucyl-L-prolyl)-L-isoleucine; isoleucyl-prolyl-isoleucine; L-Isoleucine, N-(1-L-isoleucyl-L-prolyl)-; (2S,3S)-2-((S)-1-((2S,3S)-2-Amino-3-methylpentanoyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid; H-Ile-Pro-Ile-OH. CAS No. 90614-48-5. Pack Sizes: 500 mg. Product ID: BAT-010802. Molecular formula: C17H31N3O4. Mole weight: 341.45. Custom synthesis is available. Send your inquiries for more information.
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DSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Pharmaceutical. Alternative Names: Disuccinimidyl suberate; Suberic acid bis(N-hydroxysuccinimide ester); Di(N-succinimidyl) Suberate; Octanedioic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester; 1,1'-[(1,8-Dioxooctane-1,8-diyl)bis(oxy)]di(pyrrolidine-2,5-dione). CAS No. 68528-80-3. Pack Sizes: 100 g. Product ID: BAT-006481. Molecular formula: C16H20N2O8. Mole weight: 368.34. Custom synthesis is available. Send your inquiries for more information.
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Fmoc-3,4-dehydro-L-proline
Fmoc-3,4-dehydro-L-proline, a chemical intermediary employed in the synthesis of peptides within the biomedical sector, displays considerable promise with regard to the treatment of conditions such as cancer and Alzheimer's disease. Its potential medical applications are extensive and merit further exploration. Group: Pharmaceutical. Alternative Names: Fmoc-3,4-dehydro-L-Pro-OH; (S)-Fmoc-3,4-dehydro-pyrrolidine-2-carboxylic acid. CAS No. 135837-63-7. Pack Sizes: 1 g. Product ID: BAT-007331. Molecular formula: C20H17NO4. Mole weight: 335.36. Custom synthesis is available. Send your inquiries for more information.
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Fmoc-trans-4-methyl-L-Pro-OH
Fmoc-trans-4-methyl-L-Pro-OH. Group: Pharmaceutical. Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-(2S,4R)-4-methylproline; 1-(9H-Fluorene-9-ylmethoxycarbonyl)-4beta-methyl-L-proline; Fmoc-trans-4-Amc-OH; Fmoc-trans-4-methyl-L-proline; (2S,4R)-Fmoc-4-Methyl-L-Pro-OH; (4R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methyl-L-proline; 1,2-Pyrrolidinedicarboxylic acid, 4-methyl-, 1-(9H-fluoren-9-ylmethyl) ester, (2S,4R)-. CAS No. 333777-34-7. Pack Sizes: 50 mg. Product ID: BAT-010883. Molecular formula: C21H21NO4. Mole weight: 351.39. Custom synthesis is available. Send your inquiries for more information.
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GPRP acetate
GPRP acetate, a fibrinogen-related peptide, inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Group: Pharmaceutical. Alternative Names: Pefa 6003; Pefabloc FG; GPRP.CH3CO2H; glycyl-L-prolyl-L-arginyl-L-proline acetic acid; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid acetate; H-Gly-Pro-Arg-Pro-OH acetate. CAS No. 157009-81-9. Pack Sizes: 100 mg. Product ID: BAT-009226. Molecular formula: C18H31N7O5.C2H4O2. Mole weight: 485.53. Custom synthesis is available. Send your inquiries for more information.
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H-Pro-NH2
An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Group: Pharmaceutical. Alternative Names: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. CAS No. 7531-52-4. Pack Sizes: 1mg;1g;10g. Product ID: BAT-003438. Molecular formula: C5H10N2O. Mole weight: 114.1. Custom synthesis is available. Send your inquiries for more information.
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Levetiracetam Carboxylic Acid
An impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Group: Pharmaceutical. Alternative Names: Levetiracetam acid; 1-Pyrrolidineacetic acid, α-ethyl-2-oxo-, (αS)-; (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetic acid; 1-Pyrrolidineacetic acid, α-ethyl-2-oxo-, (S)-; 2-Pyrrolidinone-n-butyric acid; UCB-L 057. CAS No. 102849-49-0. Pack Sizes: 50 mg. Product ID: B2694-053235. Molecular formula: C8H13NO3. Mole weight: 171.2. Custom synthesis is available. Send your inquiries for more information.
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Levetiracetam EP Impurity D
the enantiomer to Levetiracetam. Group: Pharmaceutical. Alternative Names: (αR)-α-Ethyl-2-oxo-1-pyrrolidineacetamide; (R)-Levetiracetam. CAS No. 103765-01-1. Pack Sizes: 50 mg. Product ID: B0215-473717. Molecular formula: C8H14N2O2. Mole weight: 170.21. Custom synthesis is available. Send your inquiries for more information.
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L-Hydroxyproline
L-Hydroxyproline is an amino acid. It can be used as a nutrition and a flavor enhancer. Uses: L-hydroxyproline, also known as 4-hydroxyproline, is a non-protein amino acid that plays a vital role in the structure and function of collagen, the most abundant protein in the human body. in recent years, researchers have been exploring the potential applications of l-hydroxyproline in drug discovery and development due to its unique properties and biological activity. first and foremost, it is. Group: Pharmaceutical. Alternative Names: trans-4-Hydroxy-L-proline; L-4-hydroxyproline; trans-4-Hydroxyproline; H-Hyp-OH; hydroxy-L-proline; 4-Hydroxy-L-proline; trans-L-Hydroxyproline; 4-Hydroxy-2-pyrrolidinecarboxylic acid. CAS No. 51-35-4. Pack Sizes: 1 kg. Product ID: BAT-014305. Molecular formula: C5H9NO3. Mole weight: 131.13. Custom synthesis is available. Send your inquiries for more information.
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Lincomycin hydrochloride
Lincomycin hydrochloride is produced by the strain of Str. lincolnensis var. lincolnensis NRRL 2936. It's a sugar antibiotic. It has anti-gram-positive bacteria and spirochete effect, and has weak antibacterial effect on some gram-negative bacteria. It can protect mice infected with Staphylococcus aureus, Streptococcus hemolyticus and dicoccus pneumoniae by oral or subcutaneous injection. It also has effect on leptospira in vivo. It can prevent and treat respiratory diseases, such as Haemophilus parasuis, infectious pleuropneumonia, mycoplasmosis, atrophic rhinitis, etc. Group: Pharmaceutical. Alternative Names: (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galactooctopyranoside Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-D-galacto-Octopyranoside Monohydrochloride; Lincocin; Lincogap; NSC 70731; U 10149a. CAS No. 859-18-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-02653. Molecular formula: C18H35ClN2O6S. Mole weight: 443. Custom synthesis is available. Send your inquiries for more information.
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Lisinopril Impurity F
Lisinopril Impurity F is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Group: Pharmaceutical. Alternative Names: Lisinopril Cyclohexyl Analogue; (2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-cyclohexylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid. CAS No. 1132650-67-9. Pack Sizes: 10 mg. Product ID: B2694-262437. Molecular formula: C21H37N3O5. Mole weight: 411.54. Custom synthesis is available. Send your inquiries for more information.
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LOXO-101 sulfate
The sulfate salt form of LOXO-101, also called Larotrectinib, which is an ATP-competitive inhibitor of tropomyosin receptor kinases. It was approved by FDA for the treatment of metastatic solid tumors. Group: Pharmaceutical. Alternative Names: LOXO-101 sulfate; LOXO 101 sulfate; LOXO101 sulfate; Larotrectinib sulfate; (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide sulfate. CAS No. 1223405-08-0. Pack Sizes: 100 mg. Product ID: B0084-474404. Molecular formula: C21H24F2N6O6S. Mole weight: 526.51. Custom synthesis is available. Send your inquiries for more information.
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Micafungin Open-Ring Analog Sodium salt
Micafungin Open-Ring Analog Sodium salt is an impurity of Micafungin, an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Group: Pharmaceutical. Alternative Names: 5-((1S,2S,3S)-4-(((2S,3R)-5-Amino-1-((2S,3S,4S)-2-carbamoyl-3-hydroxy-4-methylpyrrolidin-1-yl)-3-hydroxy-1,5-dioxopentan-2-yl)amino)-3-((2S,4R)-1-(((2S,4R)-4,5-dihydroxy-1-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzoyl)pyrrolidine-2-carbonyl)-L-threonyl)-4-hydroxypyrrolidine-2-carboxamido)-1,2-dihydroxy-4-oxobutyl)-2-hydroxyphenyl hydrogen sulfate, Sodium Salt. CAS No. 539823-82-0. Pack Sizes: 10 mg. Product ID: B1370-071106. Molecular formula: C56H70N9NaO23S. Mole weight: 1292.26. Custom synthesis is available. Send your inquiries for more information.
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MK-8353
MK-8353 is an orally available ERK1/2 inhibitor. It exhibited antitumor activity in patients with BRAFV600-mutant melanoma. Group: Pharmaceutical. Alternative Names: (3S)-3-(methylthio)-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxamide. CAS No. 1184173-73-6. Pack Sizes: 50 mg. Product ID: B2693-291615. Molecular formula: C37H41N9O3S. Mole weight: 691.84. Custom synthesis is available. Send your inquiries for more information.
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MMAF
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: Monomethylauristatin F; Monomethyl Auristatin F; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; Monomethylauristatin Phenylalanine; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. CAS No. 745017-94-1. Pack Sizes: 10 mg. Product ID: BBF-05779. Molecular formula: C39H65N5O8. Mole weight: 731.48. Custom synthesis is available. Send your inquiries for more information.
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Motolimod
Motolimod is a small-molecule agonist of TLR8, with potential immunostimulating and antineoplastic activities. Group: Pharmaceutical. Alternative Names: VTX-2337; VTX 2337; VTX2337; Motolimod; 2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide. CAS No. 926927-61-9. Pack Sizes: 100 mg. Product ID: B0084-462238. Molecular formula: C28H34N4O2. Mole weight: 458.6. Custom synthesis is available. Send your inquiries for more information.
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N-(9-Fluorenylmethoxycarbonyl)-L-proline
N-(9-Fluorenylmethoxycarbonyl)-L-proline is a synthetic amino acid derived from proline. Group: Pharmaceutical. Alternative Names: Fmoc-Pro-OH; Fmoc-L-proline; N-Fmoc-L-proline; (S)-1-(9-Fluorenylmethoxycarbonyl)pyrrolidine-2-carboxylic acid. CAS No. 71989-31-6. Pack Sizes: 1 kg. Product ID: BAT-002065. Molecular formula: C20H19NO4. Mole weight: 337.37. Custom synthesis is available. Send your inquiries for more information.
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Nafoxidine HCl
Nafoxidine HCl is the hydrochloride salt of nafoxidine. Nafoxidine, structurally related to Tamoxifen, is a non-steroidal partial estrogen antagonist. Group: Pharmaceutical. Alternative Names: 1-[2-[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine;hydrochloride; NAFOXIDINEHYDROCHLORIDE; NafoxidineHCl; 1847-63-8; U11100A. CAS No. 1847-63-8. Pack Sizes: 1 g. Product ID: B0084-294307. Molecular formula: C29H32CINO2. Mole weight: 462.03. Custom synthesis is available. Send your inquiries for more information.
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N-(Chloroacetoxy)succinimide
N-(Chloroacetoxy)succinimide is a reagent used in the preparation of organometallic complexes and other synthetic probes for the labeling of proteins. Group: Pharmaceutical. Alternative Names: 1-[(chloroacetyl)oxy]pyrrolidine-2,5-dione; 2-chloro-Acetic acid 2,5-dioxo-1-pyrrolidinyl ester. CAS No. 27243-15-8. Pack Sizes: 5 g. Product ID: B2699-335082. Molecular formula: C6H6ClNO4. Mole weight: 191.57. Custom synthesis is available. Send your inquiries for more information.
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NHS-PEG4-azide
NHS-PEG4-azide is a non-cleavable 4-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Group: Pharmaceutical. Alternative Names: Azido-PEG4-CH2CO2-NHS; N3-PEG4-C2-NHS ester; N3-PEG4-CH2CH2COONHS Ester; Azido-PEG4-NHS ester; N-Succinimidyl 15-Azido-4,7,10,13-tetraoxapentadecanoate; 2,5-Dioxopyrrolidin-1-yl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate; 1-[(1-Azido-15-oxo-3,6,9,12-tetraoxapentadecan-15-yl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(15-azido-1-oxo-4,7,10,13-tetraoxapentadec-1-yl)oxy]-. CAS No. 944251-24-5. Pack Sizes: 500 mg. Product ID: BAT-007990. Molecular formula: C15H24N4O8. Mole weight: 388.37. Custom synthesis is available. Send your inquiries for more information.
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PAR4 (1-6) (human)
PAR4 (1-6) is a synthetic hexapeptide agonist of proteinase-activated receptor 4 (PAR4). PAR4 is a thrombin receptor activated by platelet, and acts as a modulator of cellular responses that serve as hallmarks of inflammation. Group: Pharmaceutical. Alternative Names: H-Gly-Tyr-Pro-Gly-Gln-Val-OH; (2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-1-[(2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid. CAS No. 225779-44-2. Pack Sizes: 25 mg. Product ID: BAT-006098. Molecular formula: C28H41N7O9. Mole weight: 619.67. Custom synthesis is available. Send your inquiries for more information.
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phensuximide
Phensuximide is an anticonvulsant drug. It can be used for the treatment of neurological disorders stemming from the brain. Phensuximide can suppress the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures. Uses: Anticonvulsant. Group: Pharmaceutical. Alternative Names: N-Methyl-2-phenyl-succinimide; (±)-Phensuximide; 1-Methyl-3-phenyl-2,5-pyrrolidinedione; 1-Methyl-3-phenylsuccinimide; Epimid; Lifene; Milontin; Milonton; Mirontin; N-Methyl-2-phenylsuccinimide; N-Methyl-3-phenylpyrrolidinedione; N-Methyl-3-phenylsuccinimide; N-Methyl-α-phenylsuccinimide; PM 334; Phensuximid; Phensuximide; RS-Phensuximide; Racemic Phensuximide; Succitimal. CAS No. 86-34-0. Pack Sizes: 50 mg. Product ID: B0084-078550. Molecular formula: C11H11NO2. Mole weight: 189.21. Custom synthesis is available. Send your inquiries for more information.
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Protein degrader 1 hydrochloride
Protein degrader 1 hydrochloride is a building block used in the synthesis of PROTAC for the recruitment of the von Hippel-Lindau (VHL) protein. Group: Pharmaceutical. Alternative Names: (S,R,S)-AHPC hydrochloride; (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride. CAS No. 1448189-80-7. Pack Sizes: 25 mg. Product ID: B0084-007385. Molecular formula: C22H31ClN4O3S. Mole weight: 467.02. Custom synthesis is available. Send your inquiries for more information.
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Ramosetron Impurity 12
An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Group: Pharmaceutical. Alternative Names: Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanone hydrochloride; pyrrolidin-1-yl(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone; hydrochloride; VIQQUDRWPRGFBZ-UHFFFAOYSA-N; SCHEMBL9051125; DTXSID60597128; FD7376; (4,5,6,7-TETRAHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)(PYRROLIDIN-1-YL)METHANONE HCL; FT-0709212; 5-pyrrolidinocarbonyl-4,5,6,7-tetrahydrobenzimidazole hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidine hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidinehydrochloride; Methanone, 1-pyrrolidinyl(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)-, hydrochloride (1:1); Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanonehydrochloride; (Pyrrolidin-1-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)methanone--hydrogen chloride (1/1). CAS No. 132036-42-1. Pack Sizes: 50 mg. Product ID: B1803-083161. Molecular formula: C12H17N3O. Mole weight: 219.29. Custom synthesis is available. Send your inquiries for more information.
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Raxatrigine
Raxatrigine is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. It acts as a selective, small-molecule, state-dependent Nav1.7 voltage-gated sodium channel blocker. It is a peripherally and centrally acting agent that inhibits sodium channels in a state-dependent fashion. It shows selectivity for the Nav1.7 subtype over the other subtypes tested for both the resting and depolarized states. It was developed by Convergence Pharmaceuticals. It received orphan-drug designation from the US Food and Drug Administration in July 2013. It is currently in phase II studies in bipolar depression. Uses: Raxatrigine is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. it received orphan-drug designation from the us food and drug administration in july 2013. Group: Pharmaceutical. Alternative Names: (2S,5R)-5-(4-((2-fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide; GSK1014802; GSK 1014802; GSK-1014802; CNV1014802; CNV-1014802; CNV 1014802; Raxatrigine. CAS No. 934240-30-9. Pack Sizes: 25 mg. Product ID: B0084-474126. Molecular formula: C18H19FN2O2. Mole weight: 314.35. Custom synthesis is available. Send your inquiries for more information.
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RGD peptide
RGD peptide is an inhibitor of integrin-ligand interactions. Group: Pharmaceutical. Alternative Names: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. CAS No. 114681-65-1. Pack Sizes: 10 mg. Product ID: BAT-006171. Molecular formula: C23H38N10O10. Mole weight: 614.61. Custom synthesis is available. Send your inquiries for more information.
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(R)-(+)-HA-966
(R)-(+)-HA-966 is a cell-permeable antagonist/partial agonist at the glycine site of the NMDA receptor. Group: Pharmaceutical. Alternative Names: R(+)-HA-966; 1-Hydroxy-3-amino-pyrrolidine-2-one, (R)-; Tocris-0281; (R)-(+)-3-Amino-1-hydroxypyrrolidin-2-one. CAS No. 123931-04-4. Pack Sizes: 100 mg. Product ID: B1370-047738. Molecular formula: C4H8N2O2. Mole weight: 116.12. Custom synthesis is available. Send your inquiries for more information.
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(R)-N-Boc-3-pyrrolidinol
(R)-N-Boc-3-pyrrolidinol. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 109431-87-0. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: 109 (r)-1-n-boc-3-hydroxypyrrolidine.
Cenik Chemicals
SCH772984
SCH772984 is a potent and selective ERK inhibitor with potential anticancer activity. SCH722984 showed activity against BRAF mutant, NRAS mutant and wild-type melanoma. Combining vemurafenib and SCH722984 in BRAF mutant melanoma was synergistic in a majority of cell lines and significantly delayed the onset of acquired resistance in long term in vitro assays. Therefore, SCH772984 may be clinically applicable as a treatment for non-BRAF mutant melanoma or in BRAF-mutant melanoma with innate or acquired resistance, alone or in combination with BRAF inhibitors. Group: Pharmaceutical. Alternative Names: SCH-772984; SCH 772984; (R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide. CAS No. 942183-80-4. Pack Sizes: 25 mg. Product ID: B2693-429803. Molecular formula: C33H33N9O2. Mole weight: 587.688. Custom synthesis is available. Send your inquiries for more information.
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SR9011
SR9011, a synthetic REV-ERB agonist, has been found to have probable effect against sleep disorders and metabolic diseases. IC50: 790 nM and 560 nM for Rev-ErbBα and Rev-ErbBβ respectively. Group: Pharmaceutical. Alternative Names: SR 9011; SR-9011; 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-. CAS No. 1379686-29-9. Pack Sizes: 5 mg. Product ID: B2693-474529. Molecular formula: C23H31ClN4O3S. Mole weight: 479.04. Custom synthesis is available. Send your inquiries for more information.
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(S,R,S)-AHPC-Me
E3 ligase Ligand 1A is a VH032 derivate for conjugation reactions of PROTAC, which can hijack VHL as the E3 ubiquitin ligase component. Group: Pharmaceutical. Alternative Names: (S,R,S)-AHPC-Me; VHL ligand 2; E3 ligase Ligand 1A; 1-(2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-[1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide. CAS No. 1948273-02-6. Pack Sizes: 1 g. Product ID: B2693-291831. Molecular formula: C23H32N4O3S. Mole weight: 444.59. Custom synthesis is available. Send your inquiries for more information.
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(S,R,S)-AHPC-PEG1-azide
(S,R,S)-AHPC-PEG1-azide is a crosslinker-E3 ligase ligand conjugate consisting of a von Hippel-Lindau (VHL)-recruiting ligand and a PEGylated crosslinker with terminal azide for click chemistry with a target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Group: Pharmaceutical. Alternative Names: E3 ligase Ligand-Linker Conjugates 3; (S,R,S)-AHPC-PEG1-N3; (2S,4R)-1-((S)-2-(2-(2-Azidoethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. CAS No. 2101200-09-1. Pack Sizes: 100 mg. Product ID: B1370-285264. Molecular formula: C26H35N7O5S. Mole weight: 557.67. Custom synthesis is available. Send your inquiries for more information.
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Succinimidyl Acetate
Succinimidyl Acetate is a non-ionic, acidic ester of succinic anhydride, and is a chemical reagent in a variety of scientific applications. Group: Pharmaceutical. Alternative Names: N-Acetoxysuccinimide; 1-(Acetoxy)pyrrolidine-2,5-dione; Ac-Osu; N-Succinimidyl Acetate; Acetic acid N-hydroxysuccinimide ester. CAS No. 14464-29-0. Pack Sizes: 1 kg. Product ID: BAT-006391. Molecular formula: C6H7NO4. Mole weight: 157.12. Custom synthesis is available. Send your inquiries for more information.
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Turicine
Turicine, an all-natural anti-inflammatory and anti-tumor agent, is a promising biomedicine. Its power lies in its ability to interrupt the growth of malignant cells and reduce painful inflammation in ailments such as arthritis. Through its ability to regulate key signaling pathways, Turicine shows great potential as a therapeutic agent. However, further research is needed to unlock the full scope of its healing capabilities. Group: Pharmaceutical. Alternative Names: (2R,4R)-4-Hydroxy-1-dimethylpyrrolidine-2-carboxylate; (2R,4R)-2-Carboxy-4-hydroxy-1,1-dimethylpyrrolidin-1-ium; (+)-Turicine; cis-4-hydroxy-D-proline betaine; cis-hydroxyproline betaine; (2R-Cis)-2-carboxy-4-hydroxy-1,1-dimethylpyrrolidinium inner salt; Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, inner salt, (2R,4R)-; Stachydrine. CAS No. 515-24-2. Pack Sizes: 1mg;1g;10g. Product ID: 515-24-2. Molecular formula: C7H13NO3. Mole weight: 159.18. Custom synthesis is available. Send your inquiries for more information.
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Upadacitinib
Upadacitinib is a selective JAK inhibitor under the development of AbbVie.ABT-494 is nearly 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Preliminary evidence suggests that ABT-494 may spare Jak2 and Jak3 dependent signaling compared to tofacitinib. Phase II for the treatment of Atopic dermatitis and Crohn's disease, Phase III for the treatment of Rheumatoid arthritis and Ulcerative colitis was on-going. Uses: Rheumatoid arthritis; ulcerative colitis;atopic dermatitis; crohn's disease. Group: Pharmaceutical. Alternative Names: UNII-4RA0KN46E0;ABT494;(3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide. CAS No. 1310726-60-3. Pack Sizes: 5 mg. Product ID: B0084-475295. Molecular formula: C17H19F3N6O. Mole weight: 380.37. Custom synthesis is available. Send your inquiries for more information.
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VH 032-linker 6
VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Group: Pharmaceutical. Alternative Names: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. CAS No. 2098799-80-3. Pack Sizes: 200 mg. Product ID: B2693-285288. Molecular formula: C31H42N4O7S. Mole weight: 614.75. Custom synthesis is available. Send your inquiries for more information.
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VH-298
VH-298 is a high-affinity inhibitor of E3 ubiquitin ligase VHL (Kd value of 80-90 nM) that could block VHL and HIF-α interactions. VH-298 can be used in PROTAC technology. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: (2S,4R)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; EX-A1505; VH 298; VH298; VH-298. CAS No. 2097381-85-4. Pack Sizes: 50 mg. Product ID: B2693-170543. Molecular formula: C27H33N5O4S. Mole weight: 523.65. Custom synthesis is available. Send your inquiries for more information.
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Vildagliptin Impurity B
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Group: Pharmaceutical. Alternative Names: Vildagliptin Impurity 2; (2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecarbonitrile. CAS No. 1036959-23-5. Pack Sizes: 500 mg. Product ID: B2694-485168. Molecular formula: C24H33N5O3. Mole weight: 439.56. Custom synthesis is available. Send your inquiries for more information.
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Vildagliptin Related Compound A
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Group: Pharmaceutical. Alternative Names: Vildagliptin Imp.A; 2-Pyrrolidinecarbonitrile, 1-[2-(tricyclo[3.3.1.13,7]dec-1-ylamino)acetyl]-, (2S)-; Vildagliptin Deshydroxy Impurity; (S)-1-(2-((3R,5R,7R)-adamantan-1-ylamino)acetyl)pyrrolidine-2-carbonitrile. CAS No. 741657-02-3. Pack Sizes: 10 mg. Product ID: B2694-290136. Molecular formula: C17H25N3O. Mole weight: 287.4. Custom synthesis is available. Send your inquiries for more information.
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1,1-Dimethyl-3-hydroxypyrrolidinium Bromide
An impurity of Glycopyrrolate, which is an anticholinergic agent with antispasmodic activity used to treat gastrointestinal conditions associated. Group: Pharmaceutical. Alternative Names: 3-Hydroxy-1,1-dimethylpyrrolidin-1-ium bromide; Pyrrolidinium, 3-hydroxy-1,1-dimethyl-, bromide (1:1). CAS No. 51052-74-5. Pack Sizes: 100 mg. Product ID: B1370-178276. Molecular formula: C6H14BrNO. Mole weight: 196.09. Custom synthesis is available. Send your inquiries for more information.
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1-Benzyl-3-pyrrolidinone
1-Benzyl-3-pyrrolidinone Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 775-16-6. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals suppliers.
UK / EU / USA / Japan
1-Benzyl-3-pyrrolidinone
1g Pack Size. Group: Building Blocks, Organics. Formula: C11H13NO. CAS No. 775-16-6. Prepack ID : 22857708-1g. Molecular Weight : 175.23.
1-butylpyrrolidin-2-one
1-Butylpyrrolidin-2-one is a pharmaceutical intermediate used in the synthesis of drugs such as gabapentin and levetiracetam, which are used to treat neuropathic pain and epilepsy. Group: Pharmaceutical. Alternative Names: 1-Butyl-2-pyrrolidinone; 1-Butyl-2-pyrrolidone. CAS No. 3470-98-2. Pack Sizes: 250 g. Product ID: B1370-397833. Molecular formula: C8H15NO. Mole weight: 141.21. Custom synthesis is available. Send your inquiries for more information.
1-(Chloro-1-Pyrrolidinylmethylene) Pyrrolidinium tetrafluoroborate Uses: Pharmaceutical Research and Development. Group: Coupling Reagents. CAS No. 115007-14-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
UK / EU / USA / Japan
1-Methyl-2-pyrrolidinone SG
1lt Pack Size. Group: Solvents. Formula: C5H9NO. CAS No. 872-50-4. Prepack ID : 43456401-1lt. Molecular Weight : 99.13.
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