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100g Pack Size. Group: Building Blocks, Ligands, Organics. Formula: C3H4N2. CAS No. 288-13-1. Prepack ID : 55553959-100g. Molecular Weight : 68.08.
Pyrazole
25g Pack Size. Group: Building Blocks, Ligands, Organics. Formula: C3H4N2. CAS No. 288-13-1. Prepack ID : 55553959-25g. Molecular Weight : 68.08.
pyrazole-3,5-dicarboxylic acid monohydrate
pyrazole-3,5-dicarboxylic acid monohydrate Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 303180-11-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals Suppliers.
UK / EU / USA / Japan
1-(Difluoromethyl)-4-iodo-1H-pyrazole
1-(Difluoromethyl)-4-iodo-1H-pyrazole. Group: Pharmaceutical. Alternative Names: 4-Iodo-1-difluoromethylpyrazole. CAS No. 1041205-43-9. Pack Sizes: 5 g. Product ID: BB052046. Molecular formula: C4H3F2IN2. Mole weight: 243.98. Custom synthesis is available. Send your inquiries for more information.
London
1(H)-Pyrazole-1-carboxamidine hydrochloride
100g Pack Size. Group: Building Blocks, Organics. Formula: C4H7ClN4. CAS No. 4023-2-3. Prepack ID : 10315130-100g. Molecular Weight : 146.58.
1(H)-Pyrazole-1-carboxamidine hydrochloride
25g Pack Size. Group: Building Blocks, Organics. Formula: C4H7ClN4. CAS No. 4023-2-3. Prepack ID : 10315130-25g. Molecular Weight : 146.58.
1-Phenyl-3-ethoxy-5-methyl-1H-pyrazole
An impurity of Edaravone, a medication for the recovery from stroke. Group: Pharmaceutical. Alternative Names: 3-ethoxy-5-methyl-1-phenyl-1H-pyrazole; 1H-Pyrazole, 3-ethoxy-5-methyl-1-phenyl-. CAS No. 300543-31-1. Pack Sizes: 100 mg. Product ID: B0060-284947. Molecular formula: C12H14N2O. Mole weight: 202.257. Custom synthesis is available. Send your inquiries for more information.
London
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole
1-(Tetrahydro-2H-pyran-2-yl)-1H-pyrazole Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 449758-17-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals Suppliers.
An impurity of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. Alternative Names: 3-(4-methylphenyl)-5-(trifluoromethyl)pyrazole; 3-(Trifluoromethyl)-5-p-tolyl-1H-pyrazole; 3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole. CAS No. 219986-64-8. Pack Sizes: 10 mg. Product ID: B2694-309476. Molecular formula: C11H9F3N2. Mole weight: 226.2. Custom synthesis is available. Send your inquiries for more information.
London
3-Amino-1H-pyrazole-4-carbonitrile
3-Amino-1H-pyrazole-4-carbonitrile Uses: Pharmaceutical Research and Development. Group: Chemicals & Intermediates. CAS No. 16617-46-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
UK / EU / USA / Japan
3-Aminopyrazole
3-Aminopyrazole. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 1820-80-0. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: 1h-pyrazol-5-amine.
Cenik Chemicals
3-Nitro-1H-pyrazole
1g Pack Size. Group: Building Blocks, Organics. Formula: C3H3N3O2. CAS No. 26621-44-3. Prepack ID : 89985639-1g. Molecular Weight : 113.08.
3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 26033-20-5. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
UK / EU / USA / Japan
5-Amino-1-(2-hydroxyethyl)pyrazole
5-Amino-1-(2-hydroxyethyl)pyrazole, a chemical compound employed in pharmaceutical and bioactive molecule synthesis, possesses noteworthy antimicrobial and antifungal attributes, showcasing promise for drug development targeting infectious diseases. Its multifaceted properties underscore its potential application across diverse therapeutic arenas. Group: Pharmaceutical. CAS No. 73616-27-0. Pack Sizes: 1mg;1g;10g. Product ID: NP2712. Molecular formula: C5H9N3O. Mole weight: 127.14. Custom synthesis is available. Send your inquiries for more information.
London
5-Formamide-1-(2-formyloxyethl)pyrazole
5-Formamide-1-(2-formyloxyethyl)pyrazole, a versatile compound employed in pharmaceutical research for combating myriad illnesses such as cancer and inflammatory conditions. Its pivotal role as a transitional element in crafting tailored medicinal remedies epitomizes its significance in advancing personalized healthcare solutions. Group: Pharmaceutical. Alternative Names: 116856-18-9; 2-(5-Formamido-1H-pyrazol-1-yl)ethyl formate5-Formamide-1-(2-formyloxyethl)pyrazole5-Formamido-1-[2-(formyloxy)ethyl]pyrazole5-formamido-1-(2-formyloxyethyl)pyrazole. CAS No. 116856-18-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3210. Molecular formula: C7H9N3O3. Mole weight: 183.16. Custom synthesis is available. Send your inquiries for more information.
London
5-Methyl-3-(trifluoromethyl)-1H-pyrazole
5-Methyl-3-(trifluoromethyl)-1H-pyrazole. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 10010-93-2. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: 10 3-methyl-5-(trifluoromethyl)-1h-pyrazole.
Cenik Chemicals
Fipronil-[pyrazole-13C3,cyano-13C]
Labelled Fipronil. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride channels, resulting in central nervous system toxicity. Group: Pharmaceutical. Alternative Names: 5-Amino-3-cyano-13C-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]pyrazole-13C3. CAS No. 2140327-54-2. Pack Sizes: 10 mg. Product ID: BLP-008734. Molecular formula: C8[13C]4H4Cl2F6N4OS. Mole weight: 441.12. Custom synthesis is available. Send your inquiries for more information.
London
N,N'-Bis-Z-1-Guanylpyrazole
N,N'-Bis-Z-1-Guanylpyrazole Uses: Pharmaceutical R&D. Group: Coupling Reagents. Alternative Names: Pyrazol(Z)2. CAS No. 152120-55-3. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
1H-benzimidazole-5-carboxamide, scientifically known as 1-Butyl-2-{[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino}-7-methoxy, exhibits tremendous potential as an anti-cancer agent. This drug operates by impeding the growth of malignant tumors through the inhibition of enzymes engaged in cell division and DNA replication. This intricate mechanism of action has proven to be successful in the treatment of colon, lung, and breast cancer, and offers promising possibilities for cancer therapy. Group: Pharmaceutical. Alternative Names: 1H-Benzimidazole-5-carboxamide, 1-butyl-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-; 1-butyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5-carboxamide. CAS No. 2137975-08-5. Pack Sizes: 5 mg. Product ID: B0001-260292. Molecular formula: C20H26N6O3. Mole weight: 398.46. Custom synthesis is available. Send your inquiries for more information.
An impurity of Edaravone, a medication for the recovery from stroke. Group: Pharmaceutical. Alternative Names: 3,3'-dimethyl-1,1'-diphenyl-1h,1'h-4,4'-bipyrazole-5,5'-diol. CAS No. 177415-76-8. Pack Sizes: 100 mg. Product ID: B0060-284946. Molecular formula: C20H18N4O2. Mole weight: 346.39. Custom synthesis is available. Send your inquiries for more information.
London
Anle138b
Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein. Group: Pharmaceutical. Alternative Names: Anle138b; Anle 138b; Anle-138b; 5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole; 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole; anle138b. CAS No. 882697-00-9. Pack Sizes: 50 mg. Product ID: B2693-007346. Molecular formula: C16H11BrN2O2. Mole weight: 343.17. Custom synthesis is available. Send your inquiries for more information.
London
Azimsulfuron
Azimsulfuron is an acetolactate synthase inhibitor used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations. Group: Pharmaceutical. Alternative Names: N-((4,6-Dimethoxypyrimidin-2-yl)carbamoyl)-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide; DPX 47; DPX-A 8947; IN-A 894; A8947; A 8947; A-8947; 1H-Pyrazole-5-sulfonamide, N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-; 1-(4,6-Dimethoxypyrimidin-2-yl)-3-[1-methyl-4-(2-methyl-2H-tetrazol-5-yl)pyrazol-5-ylsulfonyl]urea. CAS No. 120162-55-2. Pack Sizes: 1mg;1g;10g. Product ID: 120162-55-2. Molecular formula: C13H16N10O5S. Mole weight: 424.4. Custom synthesis is available. Send your inquiries for more information.
London
Celecoxib Impurity 2
An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. Alternative Names: 1H-Pyrazole, 5-(4-methylphenyl)?-3-(trifluoromethyl)?-; 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(4-Methylphenyl)-3-trifluoromethyl-1H-pyrazole; Celecoxib Impurity H. CAS No. 948293-46-7. Pack Sizes: 10 mg. Product ID: B2694-468624. Molecular formula: C11H9F3N2. Mole weight: 226.2. Custom synthesis is available. Send your inquiries for more information.
London
E7046
E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Group: Pharmaceutical. Alternative Names: E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid. CAS No. 1369489-71-3. Pack Sizes: 50 mg. Product ID: B0084-007670. Molecular formula: C22H18F5N3O4. Mole weight: 483.39. Custom synthesis is available. Send your inquiries for more information.
London
Edaravone Impurity V
An impurity of Edaravone, a medication for the recovery from stroke. Group: Pharmaceutical. Alternative Names: 4,4-Bis(1-phenyl-3-methyl-5-oxo-3-pyrazoline-4-yl)-1-phenyl-3-methyl-1H-pyrazole-5(4H)-one. CAS No. 124009-63-8. Pack Sizes: 100 mg. Product ID: B0060-470643. Molecular formula: C30H26N6O3. Mole weight: 518.577. Custom synthesis is available. Send your inquiries for more information.
London
Edaravone Trimer
Edaravone Trimer is an impurity of Edaravone. Edaravone is a novel potent free radical scavenger that reduces reactive oxygen species, inhibits apoptosis, and blocks nonenzymatic peroxidation and lipoxygenase activity. Group: Pharmaceutical. Alternative Names: 5,?5',?5''-trimethyl-2,?2',?2''-triphenyl-[4,?4':4',?4''-Ter-4H-pyrazole]?-3,?3',?3''(2H,?2'H,?2''H)?-trione; 4,4-bis(3-methyl-5-oxo-1-phenyl(2-pyrazolin-4-yl))-3-methyl-1-phenyl-2-pyrazol in-5-one; 2-Phenyl-5-methyl-4,4-bis(2-phenyl-3-oxo-5-methyl-3,4-dihydro-2H-pyrazole-4-yl)-3,4-dihydro-2H-pyrazole-3-one. CAS No. 68195-63-1. Pack Sizes: 50 mg. Product ID: B1370-105475. Molecular formula: C30H26N6O3. Mole weight: 518.58. Custom synthesis is available. Send your inquiries for more information.
London
Ethyl Tetrazole-5-carboxylate
Ethyl Tetrazole-5-carboxylate is a reagent used in the preparation if pyrazole acids which has niacin receptor agonistic activity and is useful for the treatment of dyslipidemia. Group: Pharmaceutical. Alternative Names: Ethyl 1H-tetrazole-5-carboxylate; 1H-Tetrazole-5-carboxylic acid ethyl ester. CAS No. 55408-10-1. Pack Sizes: 1 kg. Product ID: BB029030. Molecular formula: C4H6N4O2. Mole weight: 142.12. Custom synthesis is available. Send your inquiries for more information.
London
Fipronil
Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride channels, resulting in central nervous system toxicity. Fipronil can be used to kill parasites such as fleas and lice on cats and dogs. Group: Pharmaceutical. Alternative Names: Fluocyanobenpyrazole; (RS)-5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile; 5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile; (+/-)-Fipronil; 1-(2,6-Dichloro-4-trifluoromethylphenyl)-3-cyano-5-amino-4-(trifluoromethylsulfinyl)pyrazole; Frontline Spot-on; Frontline Spray; Frontline Top Spot; Goliath gel; Granedo MC; Grenade MC; Maxforce FC; Maxforce FC Select Roach Killer Bait Gel; Over'n Out; Regent; Regent TS; Termidor; Termidor 80WG; TopChoice; RM 1601; NSC-758960. CAS No. 120068-37-3. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05824. Molecular formula: C12H4Cl2F6N4OS. Mole weight: 437.15. Custom synthesis is available. Send your inquiries for more information.
London
Halosulfuron
Halosulfuron is a herbicide used for weed control in agricultural fields. Group: Pharmaceutical. Alternative Names: 1H-Pyrazole-4-carboxylic acid, 3-chloro-5-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-1-methyl-; 3-Chloro-5-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-1-methyl-1H-pyrazole-4-carboxylic acid. CAS No. 135397-30-7. Pack Sizes: 1mg;1g;10g. Product ID: 135397-30-7. Molecular formula: C12H13ClN6O7S. Mole weight: 420.79. Custom synthesis is available. Send your inquiries for more information.
London
Halosulfuron-methyl
Halosulfuron-methyl is a herbicide used primarily to control broad-leaved and sedge weeds. Group: Pharmaceutical. Alternative Names: 1H-Pyrazole-4-carboxylic acid, 3-chloro-5-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-1-methyl-, methyl ester; A 841101; Inpool; Manage; MON 12000; MON 12037; NC 311; NC 319; Permit; Permit 75WG; Sempra; Shadow; Tribute Total; Yukon. CAS No. 100784-20-1. Pack Sizes: 1mg;1g;10g. Product ID: 100784-20-1. Molecular formula: C13H15ClN6O7S. Mole weight: 434.81. Custom synthesis is available. Send your inquiries for more information.
London
IXA4
IXA4 is a highly selective and non-toxic IRE1/XBP1s activator, which activates the IRE1/XBP1s signaling, regardless of the global activation of the unfolded protein response (UPR) or other stress-responsive signaling pathways, such as heat shock response or oxidative stress response. IXA4 reduces APP secretion by activating IRE1. IXA4 therapy improves systemic glucose metabolism and hepatic insulin action through IRE1-dependent liver transcriptomic remodeling, thereby reducing glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Group: Pharmaceutical. Alternative Names: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide; 1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-. CAS No. 1185329-96-7. Pack Sizes: 100 mg. Product ID: B1370-382267. Molecular formula: C24H28N4O4. Mole weight: 436.5. Custom synthesis is available. Send your inquiries for more information.
London
Mycro 3
Mycro 3 is potent and selective inhibitor of Myc-Max dimerization. Group: Pharmaceutical. Alternative Names: Mycro 3; Mycro3; Mycro-3; ethyl 5-[[7-[chloro(difluoro)methyl]-5-(furan-2-yl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]amino]-1-phenylpyrazole-4-carboxylate. CAS No. 944547-46-0. Pack Sizes: 10 mg. Product ID: B0084-007688. Molecular formula: C24H17ClF2N6O4. Mole weight: 526.88. Custom synthesis is available. Send your inquiries for more information.
London
Pirtobrutinib
Pirtobrutinib is a Bruton's tyrosine kinase (BTK) inhibitor and antineoplastic agent. Group: Pharmaceutical. Alternative Names: BTK inhibitor 16; LY 3527727; LOXO-305; (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4-carboxamide. CAS No. 2101700-15-4. Pack Sizes: 1 g. Product ID: B1370-372922. Molecular formula: C22H21F4N5O3. Mole weight: 479.4. Custom synthesis is available. Send your inquiries for more information.
London
Slv319
Slv319 is a potent antagonist of CB1 recceptor (Ki = 7.8 nM) used for the treatment of neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction and gastrointestinal disorders, as well as inhibits CP 55,940-induced hypotension and WIN 55,212-2-induced hypothermia in vivo. Group: Pharmaceutical. Alternative Names: Slv319; Slv 319; Slv-319; 3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide; CHEMBL158784. CAS No. 362519-49-1. Pack Sizes: 25 mg. Product ID: B0084-112540. Molecular formula: C23H20Cl2N4O2S. Mole weight: 487.399. Custom synthesis is available. Send your inquiries for more information.
London
Tartrazine
Tartrazine, a kind of azo dye, could also be used in pharmaceuticals and has been found to cause allergic and intolerance reactions in patients with asthmatics. Group: Pharmaceutical. Alternative Names: Acid Yellow 23; 4,5-Dihydro-5-oxo-1-(4-sulfophenyl)-4-[2-(4-sulfophenyl)diazenyl]-1H-pyrazole-3-carboxylic Acid Sodium Salt; Aizen Tartrazine; Vondacid Tartrazine; Wool Yellow. CAS No. 1934-21-0. Pack Sizes: 1 kg. Product ID: B1370-062020. Molecular formula: C16H9N4Na3O9S2. Mole weight: 534.37. Custom synthesis is available. Send your inquiries for more information.
London
Tolfenpyrad
Tolfenpyrad is used as foliar insecticide for the control of green peach aphids in broccoli. Group: Pharmaceutical. Alternative Names: 4-Chloro-3-ethyl-1-methyl-N-[[4-(4-methylphenoxy)phenyl]methyl]-1H-pyrazole-5-carboxamide; Tolfenpyrad; Hachihachi EC; NAI 2302; NAI-2302; NAI2302; NAI 2303; OMI 88; OMI-88; OMI88. CAS No. 129558-76-5. Pack Sizes: 5 g. Product ID: B0084-056856. Molecular formula: C21H22ClN3O2. Mole weight: 383.87. Custom synthesis is available. Send your inquiries for more information.
London
TP-10
TP-10 is a PDE10A inhibitor with IC50 of 0.8 nM. It has extremely potent PDE10A inhibitory activity and high selectivity against other PDEs. It is active in the mouse behavioral model for positive symptoms. It demonstrats good in vitro and in vivo activity. Group: Pharmaceutical. Alternative Names: TP-10; TP 10; TP10; 2-{4-[4-Pyridin-4-yl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-yl]-phenoxymethyl}-quinoline;Substituted pyrazole, 13;2-[[4-[4-pyridin-4-yl-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]phenoxy]methyl]quinoline. CAS No. 898563-00-3. Pack Sizes: 10 mg. Product ID: B0084-460312. Molecular formula: C26H19F3N4O. Mole weight: 460.45. Custom synthesis is available. Send your inquiries for more information.
London
Valdecoxib Impurity E
An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Group: Pharmaceutical. Alternative Names: Valdecoxib IMpurity-E; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzenesulfonyl chloride; 3-[4-(4-chlorosulfonylphenyl)-5-methyl-1,2-oxazol-3-yl]benzenesulfonyl chloride; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzene-1-sulfonyl chloride; YEC03863; 3-[4-[4-(Chlorosulfonyl)phenyl]-5-methyl-3-isoxazolyl]benzenesulfonyl chloride; 1-?Tert-?butyl 4-?ethyl 1H-?pyrazole-?1,?4-?dicarboxylate. CAS No. 1373038-63-1. Pack Sizes: 5 mg. Product ID: B2694-484468. Molecular formula: C16H11Cl2NO5S2. Mole weight: 432.3. Custom synthesis is available. Send your inquiries for more information.
1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: Apixaban Chloro Impurity; 1-(4-Chlorophenyl)-4,5,6,7-tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 2029205-64-7. Pack Sizes: 5 mg. Product ID: B1370-377545. Molecular formula: C24H22ClN5O3. Mole weight: 463.92. Custom synthesis is available. Send your inquiries for more information.
London
1-NA-PP1
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. Group: Pharmaceutical. Alternative Names: 1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-Naphthyl PP1. CAS No. 221243-82-9. Pack Sizes: 25 mg. Product ID: B2693-102805. Molecular formula: C19H19N5. Mole weight: 317.39. Custom synthesis is available. Send your inquiries for more information.
London
1-Phenyl-3-methyl-5-pyrazolone
500g Pack Size. Group: Analytical Reagents, Building Blocks, Peptide Reagents. Formula: C10H10N2O. CAS No. 89-25-8. Prepack ID : 70986538-500g. Molecular Weight : 174.2.
2,4,6-Tris[4-(1H-pyrazol-4-yl)phenyl]-1,3,5-triazine, an organic molecule, is notably utilized in biomedical research as a fluorescent probe, exhibiting exceptional characteristics ideal for detecting specific diseases and drugs. Highly stable and relatively non-toxic, this compound presents an extraordinary application in live cell imaging and in vitro assays, contributing to several biological studies and research findings. Group: Pharmaceutical. Alternative Names: H3TPTA; 1,?3,?5-Triazine, 2,?4,?6-tris[4-(1H-pyrazol-4-yl)?phenyl]?-. CAS No. 2396570-49-1. Pack Sizes: 100 mg. Product ID: B2699-370197. Molecular formula: C30H21N9. Mole weight: 507.5. Custom synthesis is available. Send your inquiries for more information.
London
2-Methyl-Celecoxib
An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Group: Pharmaceutical. Alternative Names: 4-[5-(2,4-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. CAS No. 170570-09-9. Pack Sizes: 100 mg. Product ID: B0070-468627. Molecular formula: C18H16F3N3O2S. Mole weight: 395.41. Custom synthesis is available. Send your inquiries for more information.
London
(2R,4R)-Teneligliptin
One isomer form of Teneligliptin, which is a DPP-4 inhibitor and has been found to be effective in the treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: Teneligliptin (2R,4R)-Isomer; [(2R,4R)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone. CAS No. 1404559-17-6. Pack Sizes: 10 mg. Product ID: B2694-483037. Molecular formula: C22H30N6OS. Mole weight: 426.59. Custom synthesis is available. Send your inquiries for more information.
London
3-(1H-pyrazol-1-yl)propanal
3-(1H-pyrazol-1-yl)propanal. Group: Pharmaceutical. Alternative Names: 3-pyrazol-1-yl-propionaldehyde. CAS No. 89532-43-4. Pack Sizes: 1 g. Product ID: B1370-173069. Molecular formula: C6H8N2O. Mole weight: 124.14. Custom synthesis is available. Send your inquiries for more information.
London
3-Methyl-1-(4-sulfophenyl)-2-pyrazolin-5-one
25g Pack Size. Group: Building Blocks, Organics. Formula: C10H10N2O4S. CAS No. 89-36-1. Prepack ID : 32793754-25g. Molecular Weight : 254.26.
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone. Group: Pharmaceutical. Alternative Names: 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one; 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolinone; 4-Benzoyl-2-nitroacetanilide; 1-Phenyl-3-methyl-4-benzoyl-5-pyrazolinone. CAS No. 4551-69-3. Pack Sizes: 25 g. Product ID: NP2801. Molecular formula: C17H14N2O2. Mole weight: 278.31. Custom synthesis is available. Send your inquiries for more information.
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4-Desmethyl-2-methyl Celecoxib
4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. Alternative Names: 4-[5-(2-Methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide; Celecoxib 2-Methyl Analog; 4-(5-o-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide. CAS No. 170569-99-0. Pack Sizes: 100 mg. Product ID: B2694-468625. Molecular formula: C17H14F3N3O2S. Mole weight: 381.38. Custom synthesis is available. Send your inquiries for more information.
6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is a metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: 6-{4-[(5-Amino-5-oxopentyl)amino]phenyl}-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; Des(2-oxo-1-piperidinyl)6-(4-(5-Amino-5-oxopentyl))Apixaban. CAS No. 2187409-01-2. Pack Sizes: 5 mg. Product ID: B1370-377543. Molecular formula: C25H28N6O4. Mole weight: 476.53. Custom synthesis is available. Send your inquiries for more information.
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6-Amino-4-chloro-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-chloro-1H-pyrazolo[3,4-d]pyrimidine. Group: Pharmaceutical. CAS No. 100644-65-3. Pack Sizes: 10 g. Product ID: BB000280. Molecular formula: C5H4ClN5. Mole weight: 169.57. Custom synthesis is available. Send your inquiries for more information.
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A01
A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Study showed that it potentiated BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells. Group: Pharmaceutical. Alternative Names: Smurf1-IN-A01; Smurf1INA01; Smurf1 IN A01; Smurf1 inhibitor A01; Smurf1-inhibitor-A01; A01; A 01; A-01; [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone; SMURF1 inhibitor A01. CAS No. 1007647-73-5. Pack Sizes: 1mg;1g;10g. Product ID: 1007647-73-5. Molecular formula: C22H20ClF3N4O3S. Mole weight: 512.93. Custom synthesis is available. Send your inquiries for more information.
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A-1210477
A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over other Bcl-2 family members. Group: Pharmaceutical. Alternative Names: A 1210477; A1210477; Abbvie Mcl-1 Inhibitor; 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid. CAS No. 1668553-26-1. Pack Sizes: 1mg;1g;10g. Product ID: 1668553-26-1. Molecular formula: C46H55N7O7S. Mole weight: 850.04. Custom synthesis is available. Send your inquiries for more information.
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A-1331852
A-1331852, a substituted benzothiazole, is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL (Ki ≤ 10 pM). A-1331852 is an orally apoptosis-inducing agent that may have potential as improved cancer therapeutics. Group: Pharmaceutical. Alternative Names: 3-(1-(((3r,5r,7r)-adamantan-1-yl)methyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)picolinic acid; A-1331852; A 1331852; A1331852; ABT-263; ABT-199; ABT 199; ABT199. CAS No. 1430844-80-6. Pack Sizes: 100 mg. Product ID: B0084-007703. Molecular formula: C38H38N6O3S. Mole weight: 658.81. Custom synthesis is available. Send your inquiries for more information.
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A2AR antagonist 1
A2AR antagonist 1 is a potent A2AR (Adenosine A2A Receptor) antagonist with Ki values of 4 nM and 264 nM for A2AR and A1R, respectively. Group: Pharmaceutical. Alternative Names: 1-[(2-fluorophenyl)methyl]-4-(furan-2-yl)pyrazolo[3,4-d]pyrimidin-6-amine. CAS No. 443103-97-7. Pack Sizes: 1mg;1g;10g. Product ID: 443103-97-7. Molecular formula: C16H12FN5O. Mole weight: 309.3. Custom synthesis is available. Send your inquiries for more information.
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A2B receptor antagonist 1
A potent antagonist of A2B adenosine receptor. Group: Pharmaceutical. Alternative Names: 1H-Purine-2,6-dione, 3,9-dihydro-8-[1-(phenylmethyl)-1H-pyrazol-4-yl]-1,3-dipropyl-. CAS No. 531506-36-2. Pack Sizes: 1mg;1g;10g. Product ID: 531506-36-2. Molecular formula: C21H24N6O2. Mole weight: 392.45. Custom synthesis is available. Send your inquiries for more information.
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A-770041
A-770041 is an selective and orally bioavailable pyrazolo[3,4-d]pyrimidine exhibiting selectivity for Lck compared with previously reported compounds. It is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling. It is currently in the preclinical developlent stage and no clinical data are available. Group: Pharmaceutical. Alternative Names: A-770041; A 770041; A770041. CAS No. 869748-10-7. Pack Sizes: 1mg;1g;10g. Product ID: 869748-10-7. Molecular formula: C34H39N9O3. Mole weight: 621.73. Custom synthesis is available. Send your inquiries for more information.
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A-77-01
A-77-01 is an inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5( IC50 =25nM). Uses: Potent alk5 inhibitor. Group: Pharmaceutical. Alternative Names: A77-01; A 77-01; A-77-01. 4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinoline;4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline. CAS No. 607737-87-1. Pack Sizes: 1mg;1g;10g. Product ID: 607737-87-1. Molecular formula: C18H14N4. Mole weight: 286.34. Custom synthesis is available. Send your inquiries for more information.
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AB-680 ammonium
AB-680 ammonium is a highly potent, reversible and selective CD73 (an ecto-nucleotidase) inhibitor, with a Ki of 4.9 pM for hCD73, and displays >10,000-fold selectivity over related ecto-nucleotidases CD39. It has antitumor activity. Group: Pharmaceutical. Alternative Names: 6-Chloro-N-[(1S)-1-(2-fluorophenyl)ethyl]-1-{5-O-[hydroxy(phosphonomethyl)phosphoryl]-β-D-ribofuranosyl}-1H-pyrazolo[3,4-b]pyridin-4-amine ammonium (1:2). Pack Sizes: 1mg;1g;10g. Molecular formula: C20H30ClFN6O9P2. Mole weight: 614.89. Custom synthesis is available. Send your inquiries for more information.
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ABD459
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). Group: Pharmaceutical. Alternative Names: [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl](4-methoxyphenyl)-methanone. CAS No. 1047670-51-8. Pack Sizes: 1mg;1g;10g. Product ID: 1047670-51-8. Molecular formula: C24H17BrCl2N2O2. Mole weight: 516.2. Custom synthesis is available. Send your inquiries for more information.
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AC410
AC410 is a Janus kinase 2 (JAK2) inhibitor with Kd of 0.18 nM. AC410 is selective for JAK2 and Kd is 2.5 nM for JAK1 and 5nM for JAK3. Phase I for the treatment of Autoimmune disorders and Inflammation is on-going. Uses: Autoimmune disorders; inflammation. Group: Pharmaceutical. Alternative Names: AC410; AC 410; AC-410; (S)-(4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol;1361415-86-2 (HCl). CAS No. 1361415-84-0. Pack Sizes: 1mg;1g;10g. Product ID: 1361415-84-0. Molecular formula: C19H16FN5O. Mole weight: 349.4. Custom synthesis is available. Send your inquiries for more information.
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Apixaban Acid
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; Apixaban Impurity 41. CAS No. 503614-92-4. Pack Sizes: 100 mg. Product ID: B2694-376320. Molecular formula: C25H24N4O5. Mole weight: 460.5. Custom synthesis is available. Send your inquiries for more information.
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Apixaban Dehydro Impurity
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Group: Pharmaceutical. Alternative Names: 4,5-Dehydro Apixaban; 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide. CAS No. 1074549-89-5. Pack Sizes: 10 mg. Product ID: B2694-466680. Molecular formula: C25H23N5O4. Mole weight: 457.49. Custom synthesis is available. Send your inquiries for more information.
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APY29
Allosteric modulator of IRE1α. Inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α ribonuclease activity. Group: Pharmaceutical. Alternative Names: APY29; APY-29; APY 29; N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine. CAS No. 1216665-49-4. Pack Sizes: 10 mg. Product ID: B2693-463139. Molecular formula: C17H16N8. Mole weight: 332.36. Custom synthesis is available. Send your inquiries for more information.
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Asciminib
Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Uses: Tyrosine kinase inhibitors. Group: Pharmaceutical. Alternative Names: ABL-001; ABL 001; ABL001; N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide. CAS No. 1492952-76-7. Pack Sizes: 10 mg. Product ID: B0084-007699. Molecular formula: C20H18ClF2N5O3. Mole weight: 449.843. Custom synthesis is available. Send your inquiries for more information.
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Asciminib-[15N,d4]
Asciminib-[15N,d4] is the labelled analogue of Asciminib. Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Group: Pharmaceutical. Alternative Names: [15N,2H4]-Asciminib; (R)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)nicotinamide[15N,2H4]. Pack Sizes: 1 mg. Product ID: BLP-014882. Molecular formula: C20H14D4ClF2N4[15N]O3. Mole weight: 454.86. Custom synthesis is available. Send your inquiries for more information.
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AT13148
AT13148 is an orally available multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. It can block phosphorylation of AKT, p70S6K, PKA, ROCK and SGK substrates, and induce apoptosis in cancer cells. Group: Pharmaceutical. Alternative Names: AT-13148; (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol. CAS No. 1056901-62-2. Pack Sizes: 50 mg. Product ID: B0084-462670. Molecular formula: C17H16ClN3O. Mole weight: 313.78. Custom synthesis is available. Send your inquiries for more information.
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AZ-960
AZ-960 is an ATP-competitive inhibitor of JAK2 with Ki value of 0.45 nM. It inhibits proliferation in a SET-2 human megakaryoblastic cell line harboring the JAK2V617F mutation with GI50 value of 33 nM. Group: Pharmaceutical. Alternative Names: (S)-5-Fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile; 3-Pyridinecarbonitrile, 5-fluoro-2-(((1S)-1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)-; 5-Fluoro-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-6-[(5-methyl-1H-pyrazol-3-yl)amino]nicotinonitrile. CAS No. 905586-69-8. Pack Sizes: 50 mg. Product ID: B1370-286345. Molecular formula: C18H16F2N6. Mole weight: 354.36. Custom synthesis is available. Send your inquiries for more information.
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AZD3965
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. Alternative Names: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. Custom synthesis is available. Send
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AZD-4547
AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. Group: Pharmaceutical. Alternative Names: AZD-4547; AZD 4547; AZD4547; N-{3-[2-(3,5-Dimethoxyphenyl)ethyl]-1h-Pyrazol-5-Yl}-4-[(3r,5s)-3,5-Dimethylpiperazin-1-Yl]benzamide. CAS No. 1035270-39-3. Pack Sizes: 100 mg. Product ID: B0084-456576. Molecular formula: C26H33N5O3. Mole weight: 463.582. Custom synthesis is available. Send your inquiries for more information.
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Baricitinib
Baricitinib is a selective and orally bioactive inhibitor of JAK1 and JAK2. It has been approved by FDA for the treatment of rheumatoid arthritis (RA). Uses: The treatment of rheumatoid arthritis (ra). Group: Pharmaceutical. Alternative Names: LY3009104; 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile; Olumiant. CAS No. 1187594-09-7. Pack Sizes: 1 g. Product ID: B0084-457382. Molecular formula: C16H17N7O2S. Mole weight: 371.419. Custom synthesis is available. Send your inquiries for more information.
London
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