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| Product | Description | |
|---|---|---|
| Purine Derivatives | Purine Derivatives represent a cornerstone in biomedical sciences, vital for synthesizing therapeutic agents like allopurinol, targeting gout via xanthine oxidase inhibition. Their critical functionality extends to anticancer and antiviral domains, offering potential solutions for managing viral infections, such as HIV and hepatitis, thus fortifying therapeutic interventions across diverse pathologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 8-Iodo-guanosine | 8-Iodo-guanosine, a chemical compound used in biomedical research, has proven instrumental in studying the impacts of purine nucleoside analogs on cancers and viral infections. As an iodine-substituted guanosine derivative, it exhibits the potential to act as an inhibitor of RNA viruses like HIV and hepatitis C. Group: Pharmaceutical. CAS No. 18438-99-8. Pack Sizes: 1 g. Product ID: B1370-004370. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bendamustine hydrochloride | Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. Group: Pharmaceutical. CAS No. 3543-75-7. Pack Sizes: 500 mg. Product ID: NP3323. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N- [ [ [ (1R) -2- (6-Amino-9H-purin-9-yl) -1-methylethoxy] methyl] hydroxyphosphinyl] -D-alanine | An impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Group: Pharmaceutical. CAS No. 376633-24-8. Pack Sizes: 50 mg. Product ID: B2694-085564. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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