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| Product | Description | |
|---|---|---|
| Purmorphamine | Purmorphamine, under the IUPAC name 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine, is a cell-permeable 6,9-trisubstituted purine which directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ).So it has been shown to activate the Hedgehog (Hh) signaling pathway which is important for regulating embryonic patterning, stem cell renewal, and tissue regeneration. In vitro: An activator of the hedgehog (Hh) signaling pathway by directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ). In vivo: Purmorphamine up-regulates ALP expression in human mesenchymal stem cell-based constructs on rats. Uses: Directly binds and activates smoothened (in hek293t cell:ic50= ~ 1.5 μm ); an activator of the hedgehog (hh) signaling pathway; an inducer of osteoblast differentiation (ec50= 1 μm). Group: Pharmaceutical. CAS No. 483367-10-8. Pack Sizes: 100 mg. Product ID: B0084-211514. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 1,4-Butanediol, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-, 1,4-diacetate | An impurity of Famciclovir, a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. Group: Pharmaceutical. CAS No. 174155-69-2. Pack Sizes: 10 mg. Product ID: B1370-244938. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl Benzoate | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. CAS No. 59277-91-7. Pack Sizes: 50 mg. Product ID: B0093-007231. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Amino-6-purinethiol (6-Thioguanine) | 1g Pack Size. Group: Analytical Reagents, Bioactive Small Molecules. Formula: C5H5N5S. CAS No. 154-42-7. Prepack ID : 66238710-1g. Molecular Weight : 167.19. |  |
| N- [ [ [ (1R) -2- (6-Amino-9H-purin-9-yl) -1-methylethoxy] methyl] hydroxyphosphinyl] -D-alanine | An impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Group: Pharmaceutical. CAS No. 376633-24-8. Pack Sizes: 50 mg. Product ID: B2694-085564. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine | (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine, an important compound, is frequently utilized in scientific endeavors towards the development of medications for the treatment of diverse ailments, encompassing cancer and autoimmune diseases. Typically employed as a substrate for enzymes participating in the purine metabolic pathway, this substance exhibits notably high perplexity, owing to its intricate chemical composition. In addition, it boasts considerable burstiness, with some instances of relatively lucid nomenclature alongside more elaborative descriptions of its molecular properties. Uses: A novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder. Group: Pharmaceutical. CAS No. 979-92-0. Pack Sizes: 100 mg. Product ID: B0001-080350. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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