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| Product | Description | |
|---|---|---|
| PseudoUridine 5'-monophosphate Sodium salt | A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Group: Pharmaceutical. Alternative Names: Pseudouridylic acid sodium salt; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol sodium salt; pseudouridine 5'-phosphate sodium salt; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione sodium salt; 5-b-D-Ribofuranosyluracil 5'-phosphate sodium salt; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate, sodium salt; pUMP Sodium Salt. Pack Sizes: 100 mg. Product ID: B1370-285301. Molecular formula: C9H13N2O9P.xNa. Mole weight: 324.18 (free acid). Custom synthesis is available. Send your inquiries for more information. |  London |
| PseudoUridine 5'-Triphosphate Sodium | PseudoUridine 5'-Triphosphate Sodium is a compound, finding extensive employment in the exploration of RNA modifications and nucleotide analogs. Group: Pharmaceutical. Alternative Names: pUTP Sodium; Sodium ((2R,3S,4R,5S)-5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione Sodium salt; Pseudo UTP Sodium salt; 5-Ribosyl Uraci Sodium salt; 5-β-D-Ribofuranosyluracil 5'-Triphosphate Sodium Salt; Pseudouridine Triphosphate Sodium Salt; PseudoUridine 5'-Triphosphate; Pseudo UTP; Pseudo-UTP. Pack Sizes: 1 mL. Product ID: B2706-358098. Molecular formula: C9H15N2O15P3.xNa. Mole weight: 484.14 (free acid). Custom synthesis is available. Send your inquiries for more information. | London |
| 1-MethylpseudoUridine | N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. Group: Pharmaceutical. Alternative Names: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-. CAS No. 13860-38-3. Pack Sizes: 1 g. Product ID: B2706-207673. Molecular formula: C10H14N2O6. Mole weight: 258.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences. Group: Pharmaceutical. Alternative Names: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5'-O-DMTr-2'-O-TBDMS-Pseudouridine-3'-CE Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-Pseudouridine-3'-cyanoethyl-Phosphoramidite. CAS No. 163496-23-9. Pack Sizes: 1 g. Product ID: B2706-337807. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. Custom synthesis is available. Send your inquiries for more information. | London |
| β-pseudoUridine | An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that Beta-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes. Group: Pharmaceutical. Alternative Names: Pseudouridine; ψ-Uridine; 5-(β-D-Ribofuranosyl)uracil; b-pseudoUridine; 5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; 5-Ribosyluracil; NSC 162405; Pseudouridine C; β-D-Pseudouridine; pseudo-Uridine; Pseudouracil; Pseudouridine; β-Pseudouridine; 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 1445-07-4. Pack Sizes: 5 g. Product ID: BBF-04654. Molecular formula: C9H12N2O6. Mole weight: 244.2. Custom synthesis is available. Send your inquiries for more information. | London |
| N1-(1,1-Difluoroethyl)pseudoUridine | N1-(1,1-Difluoroethyl)pseudoUridine is a compound, used to study a spectrum of pernicious viral infections by restraining the synthesis of rogue RNA. Group: Pharmaceutical. Alternative Names: 1-(1,1-Difluoroethyl)pseudouridine. Pack Sizes: 5 mg. Product ID: B1370-358087. Molecular formula: C11H14F2N2O6. Mole weight: 308.24. Custom synthesis is available. Send your inquiries for more information. | London |
| N1-BenzylpseudoUridine | N1-BenzylpseudoUridine, a cutting-edge biomedical marvel, emerges as an ingenious solution to combat various ailments. Its remarkable prowess lies in its potential to exhibit antiviral properties, rendering it a captivating prospect for conquering RNA viruses. Additionally, its inhibitory effect on cancer cell proliferation makes it an alluring candidate for tailored therapeutic interventions. Scientists are diligently conducting further investigations to unleash its therapeutic potential against specific viral infections and malignant conditions, illuminating the path toward unprecedented medical breakthroughs. Group: Pharmaceutical. Alternative Names: 1-Benzyl-pseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-(phenylmethyl)-5-β-D-ribofuranosyl-; 1-benzyl-5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. CAS No. 1613530-22-5. Pack Sizes: 10 mg. Product ID: B1370-339033. Molecular formula: C16H18N2O6. Mole weight: 334.32. Custom synthesis is available. Send your inquiries for more information. | London |
| N1-EthylpseudoUridine | N1-EthylpseudoUridine is an indispensable compound in the biomedical field, demonstrating profound applications encompass disease research, prevention and intervention. This exceptional substance exhibits unparalleled potential in studying viral onslaughts, malignant neoplasms and neurologic afflictions. Group: Pharmaceutical. Alternative Names: 1-Ethylpseudouridine; 1-ethyl-pseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-ethyl-5-β-D-ribofuranosyl-; 1-Ethyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione. CAS No. 1613529-72-8. Pack Sizes: 5 mg. Product ID: B1370-339943. Molecular formula: C11H16N2O6. Mole weight: 272.25. Custom synthesis is available. Send your inquiries for more information. | London |
| N1-Methoxymethyl pseudouridine | N1-Methoxymethyl pseudouridine is a remarkable biomedical compound, used for developing targeted drug delivery systems and studying gene therapy. Group: Pharmaceutical. Alternative Names: 1-Methoxymethylpseudouridine; N1-Methoxymethyl pseudouridine; 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-(methoxymethyl)pyrimidine-2,4-dione. Pack Sizes: 5 mg. Product ID: B1370-358091. Molecular formula: C11H16N2O7. Mole weight: 288.25. Custom synthesis is available. Send your inquiries for more information. | London |
| N1-MethylpseudoUridine-5'-Triphosphate Sodium | It is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The product has passed the functionality test in transcription reaction. The solution is free of DNase and RNase contamination. Group: Pharmaceutical. Alternative Names: N1-Me-pUTP Sodium salt; 1-Methylpseudouridine-5'-Triphosphate sodium salt; N1-Methylpseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-, sodium salt; 1-Methylpseudo-UTP sodium salt; N1-methyl-pseudouridine 5'-triphosphate, sodium salt. Pack Sizes: 1 mL. Product ID: B2706-358101. Molecular formula: C10H17N2O15P3.xNa. Mole weight: 498.17 (free acid). Custom synthesis is available. Send your inquiries for more information. | London |
| N1,N3-Bis(cyanomethyl)pseudoUridine | N1,N3-Bis(cyanomethyl)pseudoUridine, a compound employed in the production of antiviral drugs aimed at combating viral infections spanning coronaviruses, designates a formidable inhibitor of viral RNA generation, disallowing virus replication. Elucidating its further capabilities, studies suggest this compound exhibits prospective implications in tumor therapy, acting as a growth-reducing agent for malignant cells. Group: Pharmaceutical. Alternative Names: 1,3-Bis(cyanomethyl)pseudouridine. Pack Sizes: 5 mg. Product ID: B1370-358092. Molecular formula: C13H14N4O6. Mole weight: 322.27. Custom synthesis is available. Send your inquiries for more information. | London |
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