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Product
Proteinase K 100mg Pack Size. Group: Biochemicals, Diagnostic Raw Materials, Research Organics & Inorganics. Formula: C29H27N2O12P. CAS No. 39450-01-6. Prepack ID : 49085587-100mg. Molecular Weight : 626.5. Molekula
Proteinase K Proteinase K is a subtilisin-related serine protease. It was discovered from the fungus Engyodontium album. It can be used for removal of endogenous nucleases during the preparation of DNA and RNA, and for preparation of tissue sections for in situ hybridization. It is often used in pH range 7.5-9.0 and 37-70°C. Specific activity is ≥ 34 units/mg of protein. Group: Pharmaceutical. Alternative Names: EC 3.4.21.64; endopeptidase K; Tritirachium alkaline proteinase; Tritirachium album serine proteinase; Tritirachium album proteinase K. CAS No. 39450-01-6. Pack Sizes: 1 g. Product ID: BBF-04168. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
AY-NH2 AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Group: Pharmaceutical. Alternative Names: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. CAS No. 352017-71-1. Pack Sizes: 5 mg. Product ID: BAT-006106. Molecular formula: C34H48N8O7. Mole weight: 680.79. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Calpeptin Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively. Uses: Cysteine proteinase inhibitors. Group: Pharmaceutical. Alternative Names: Benzylcarbonyl-leu-nleu-H; Cbz-Leu-Nle-al. CAS No. 117591-20-5. Pack Sizes: 100 mg. Product ID: B2693-161534. Molecular formula: C20H30N2O4. Mole weight: 362.46. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
E-64 E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain. Uses: For research used only. Group: Pharmaceutical. Alternative Names: L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide; Proteinase inhibitor E 64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid; Thiol protease inhibitor; trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane; 2-Oxiranecarboxylic acid, 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-, (2S,3S)-; L-Trans-Epoxysuccinyl-Leu-agmatine. CAS No. 66701-25-5. Pack Sizes: 50 mg. Product ID: BAT-015060. Molecular formula: C15H27N5O5. Mole weight: 357.41. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
FOY 251 FOY 251 is a metabolite of camostat mesilate, and a proteinase inhibitor. Group: Pharmaceutical. Alternative Names: Foy 251;71079-09-9;4-(4-Guanidinobenzoyloxy)phenylacetic acid;FOY-251 mesylate;FOY251;4-GBCE (methanesulfonate);2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt;2-[4-[4-(diaminomethylideneamino)benzoyl]oxyphenyl]acetic acid;methanesulfonic acid;CHEMBL433135;FOY-251 mesylate?;4-[[4-[(AMINOIMINOMETHYL)AMINO]BENZOYL]OXY]-BENZENEACETIC ACID MONOMETHANESULFONATE;SCHEMBL1649708;SCHEMBL11417275;DTXSID20991365;EX-A5589;HY-19727A;MFCD09842546;s3511;AKOS030614588;CS-0016501;EN300-7455534;4-(4-Guanidinobenzoyloxy)-phenylacetic acid x Methanesulfonic acid;2-[4-(4-carbamimidamidobenzoyloxy)phenyl]acetic acid; methanesulfonic acid;[4-(4-CARBAMIMIDAMIDOBENZOYLOXY)PHENYL]ACETIC ACID; METHANESULFONIC ACID;{4-[(4-Carbamimidamidobenzoyl)oxy]phenyl}acetic acid--methanesulfonic acid (1/1);2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid compound with methanesulfonic acid (1:1);2-(4-((4-guanidinobenzoyl)oxy)phenyl)acetic acid--methanesulfonic acid (1/1);Benzeneacetic acid, 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-, monomethanesulfonate. CAS No. 71079-09-9. Pack Sizes: 5 mg. Product ID: B2693-115860. Molecular formula: C9H10BrFN2O5. Mole weight: 325.09. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PAR-2 (1-6) (mouse, rat) PAR-2 (1-6) (mouse, rat) is a PAR2 activator. It can be used to explore signaling through PAR2 in cells. Group: Pharmaceutical. Alternative Names: H-Ser-Leu-Ile-Gly-Arg-Leu-OH; Proteinase Activated Receptor 2 Agonist Peptide (SLIGRL), mouse; Ser-Leu-Ile-Gly-Arg-Leu; PAR-2 Agonist Peptide (SLIGRL), mouse. CAS No. 164081-25-8. Pack Sizes: 10 mg. Product ID: BAT-006097. Molecular formula: C29H55N9O8. Mole weight: 657.8. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PAR4 (1-6) (human) PAR4 (1-6) is a synthetic hexapeptide agonist of proteinase-activated receptor 4 (PAR4). PAR4 is a thrombin receptor activated by platelet, and acts as a modulator of cellular responses that serve as hallmarks of inflammation. Group: Pharmaceutical. Alternative Names: H-Gly-Tyr-Pro-Gly-Gln-Val-OH; (2S)-2-[[(2S)-5-amino-2-[[2-[[(2S)-1-[(2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid. CAS No. 225779-44-2. Pack Sizes: 25 mg. Product ID: BAT-006098. Molecular formula: C28H41N7O9. Mole weight: 619.67. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Protease-Activated Receptor-2 Activating Peptide LIGRL-NH2 is a PAR2 activator with EC50 value of ~5 μM. It can be used to explore signaling through PAR2 in cells. Group: Pharmaceutical. Alternative Names: Thrombin Receptor-Like 1 (1-6) amide (mouse, rat); SLIGRL amide; Proteinase Activated Receptor 2 (1-6) amide (mouse, rat); Coagulation Factor II Receptor-Like 1 (1-6) amide (mouse, rat); PAR-2 (1-6) amide (mouse, rat); Ser-Leu-Ile-Gly-Arg-Leu-NH2; L-Seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucinamide. CAS No. 171436-38-7. Pack Sizes: 10 mg. Product ID: BAT-006095. Molecular formula: C29H56N10O7. Mole weight: 656.82. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Protease-Activated Receptor-2, amide SLIGKV-NH2 is a protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM; IC50 = 10.4 μM). Group: Pharmaceutical. Alternative Names: Thrombin Receptor-Like 1 (1-6) amide (human); SLIGKV amide; Proteinase Activated Receptor 2 (1-6) amide (human); Coagulation Factor II Receptor-Like 1 (1-6) amide (human); Ser-Leu-Ile-Gly-Lys-Val; PAR2 activating peptide; PAR2-AP; PAR-2 (1-6) Human; L-seryl-L-leucyl-L-isoleucyl-glycyl-L-lysyl-L-valinamide. CAS No. 190383-13-2. Pack Sizes: 25 mg. Product ID: BAT-006099. Molecular formula: C28H54N8O7. Mole weight: 614.78. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
TMC-58B Aurantiamide, a natural alkaloid found in the herbs of Walsura yunnanensis, is used as significant anti-inflammatory and antinociceptive. it can serve as the natural compound for inhibiting cysteine proteinases, in particular, cathepsin L (3.4.22.15) and B (3.4.22.1) with IC50 of 12 microM and 49 microM, respectively. It may suppress the growth of malignant gliomas by blocking autophagic flux. Uses: Anti-neuroinflammatory; anti-inflammatory; antinociceptive. Group: Pharmaceutical. Alternative Names: (S)-α-(Benzoylamino)-N-[(S)-1-(hydroxymethyl)-2-phenylethyl]benzenepropanamide. CAS No. 58115-31-4. Pack Sizes: 1 mg. Product ID: NP0417. Molecular formula: C25H26N2O3. Mole weight: 402.5. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
VKGILS-NH2 VKGILS-NH2 is a reversed control peptide for SLIGKV-NH2, which is a protease-activated receptor 2 (PAR2) agonist. Group: Pharmaceutical. Alternative Names: retro-PAR-2 (1-6) amide (human); retro-SLIGKVamide; Thrombin Receptor-Like 1 (6-1) amide (human); Proteinase Activated Receptor 2 (6-1) amide (human); PAR-2 (6-1) amide (human). CAS No. 942413-05-0. Pack Sizes: 10 mg. Product ID: BAT-006100. Molecular formula: C28H54N8O7. Mole weight: 614.79. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Z-DEVD-FMK Z-DEVD-FMK is a cell-permeant, irreversible caspase-3 inhibitor that can be used as an anaesthetic agent. It has been shown to suppress tumor cell apoptosis. Uses: Cysteine proteinase inhibitors. Group: Pharmaceutical. Alternative Names: Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK; Caspase-3 Inhibitor; Z-D(OMe)E(Ome)VD(OMe)-FMK; benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone; Caspase-3 Inhibitor II; Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone; Z-DEVD-fluoromethylketone. CAS No. 210344-95-9. Pack Sizes: 10 mg. Product ID: BAT-010236. Molecular formula: C30H41FN4O12. Mole weight: 668.67. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Z-Phe-DL-Ala-FMK Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages. Uses: Cysteine proteinase inhibitors. Group: Pharmaceutical. Alternative Names: Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester. CAS No. 197855-65-5. Pack Sizes: 50 mg. Product ID: B0084-209259. Molecular formula: C21H23FN2O4. Mole weight: 386.42. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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