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| Product | Description | |
|---|---|---|
| D-Val-Leu-Lys 4-nitroanilide dihydrochloride | D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Group: Pharmaceutical. CAS No. 62354-43-2. Pack Sizes: 5 mg. Product ID: BAT-014255. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Abz-Ala-Phe-Ala-Phe-Asp-Val-Phe-3-nitro-Tyr-Asp-OH | Abz-Ala-Phe-Ala-Phe-Asp-Val-Phe-3-nitro-Tyr-Asp-OH is a fluorogenic (FRET) substrate for endoproteinase AspN, Asp-specific proteases from Staphylococcus aureus, Bacillus licheniformis and Streptomyces griseus. Group: Pharmaceutical. CAS No. 143147-74-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015248. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Abu-Tle-Leu-Gln-AMC | Ac-Abu-Tle-Leu-Gln-AMC is a fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016025. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Arg-Leu-Arg-AMC | Ac-Arg-Leu-Arg-AMC is a fluorogenic substrate for the determination of the trypsin-like activity of purified proteasomes (Km = 78 μM). Group: Pharmaceutical. CAS No. 929903-87-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014565. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Gly-Ala-Lys(Ac)-AMC | Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate used to measure histone deacetylase class I (HDAC 1, 2, 3 and 8) and class II (HDAC 6 and 10) activity in protease coupling assays. Ac-GAK-AM is formed from lysine deacetylation catalyzed by HDAC. Group: Pharmaceutical. CAS No. 577969-56-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015374. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-IEPD-AFC | Ac-IEPD-AFC is a peptide whose sequence is preferred recognition motif for the serine protease granzyme B. It is a fluorogenic substrate. Group: Pharmaceutical. CAS No. 1135417-31-0. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-010421. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Ile-Glu-Pro-Asp-AMC | Ac-Ile-Glu-Pro-Asp-AMC is a preferred substrate sequence of granzyme B, which is a mammalian serine protease involved in the induction of rapid target cell death by cytotoxic lymphocytes. Group: Pharmaceutical. CAS No. 216757-33-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015136. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Lys-Gln-Leu-Arg-AFC | Ac-Lys-Gln-Leu-Arg-AFC is the optimal substrate for human Hepsin, because KQLR/VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm. Hepsin is a membrane-anchored serine protease that is overexpressed in ovarian, prostate cancer and renal cell carcinomas, and therefore can be used as a prognostic marker. Group: Pharmaceutical. CAS No. 1802078-38-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014545. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Nle-Pro-Nle-Asp-AMC | Ac-Nle-Pro-Nle-Asp-AMC is a substrate for proteasomes. It can be cleaved by the caspase-like site of proteasome, also known as postglutamyl peptide hydrolase (PGPH). AMC (7-amino-4-methylcoumarin) is released and produces the fluorescence utilized to quantify the caspase-like site activity. Ac-Nle-Pro-Nle-Asp-AMC also inhibits the chymotrypsin-like activity of the proteasome allosterically when bound to the caspase-like site. Group: Pharmaceutical. CAS No. 355140-49-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015113. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Boc-GRR-AMC TFA | Boc-GRR-AMC (TFA) is a tri-peptide Substrate. BOC-GRR-AMC is cleaved by type II Metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana. It is a substrate for flavivirus proteases such as West Nile virus protease, yellow fever virus NS3 protease, and dengue virus NS2B-NS3 protease. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: BAT-016508. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Boc-LRR-AMC (trifluoroacetate salt) | Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Group: Pharmaceutical. Pack Sizes: 50 mg. Product ID: BAT-016477. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ML241 | ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer. Uses: Anticancer. Group: Pharmaceutical. CAS No. 1346528-06-0. Pack Sizes: 100 mg. Product ID: B0084-475332. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt | N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Group: Pharmaceutical. CAS No. 88793-79-7. Pack Sizes: 50 mg. Product ID: BAT-010163. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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