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| Product | Description | |
|---|---|---|
| Prostaglandin A1 Impurities | Prostaglandin A1 Impurities, as quintessential components in the biomedical sphere, underpin rigorous quality control and safety evaluation protocols in the synthesis of prostaglandin-based medications. Their utilization spans the authentication of cardiovascular and inflammatory therapies, thus augmenting therapeutic accuracy and optimizing pharmaceutical interventions for superior clinical outcomes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Prostaglandin A2 Impurities | Prostaglandin A2 Impurities are critical in the quality control and research of prostaglandin-based therapies. These compounds are used in the synthesis and characterization of drugs targeting inflammatory diseases, such as rheumatoid arthritis and cardiovascular disorders, by providing insights into the degradation and stability of pharmaceutical formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Prostaglandin B1 Impurities | Prostaglandin B1 Impurities, indispensable in biomedical research, are crucial for evaluating prostaglandin-based drug purity and efficacy. These impurities aid in refining formulations for cardiovascular treatments, targeting ailments like hypertension and ischemic heart disease, thereby assuring optimal drug safety and therapeutic efficacy whilst maintaining rigorous scientific standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Prostaglandin derivative | Prostaglandin derivative. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 87007-31-6. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| Prostaglandin E1 | 1mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H34O5. CAS No. 745-65-3. Prepack ID : 13337083-1mg. Molecular Weight : 354.48. |  |
| Prostaglandin E1 | Prostaglandin-E1 is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It can be used as a vasodilator agent increasing peripheral blood flow. Uses: The treatment of erectile dysfunction, vasodilator agent. Group: Pharmaceutical. CAS No. 745-65-3. Pack Sizes: 50 mg. Product ID: B0084-299024. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Prostaglandin E1 Impurities | Prostaglandin E1 Impurities, integral in the biomedical industry, are pivotal in optimizing the pharmacological profiling of Prostaglandin E1, a drug crucial for treating erectile dysfunction and critical limb ischemia. These impurities assist in refining the safety and efficacy of formulations, enhancing therapeutic outcomes and minimizing adverse effects. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Prostaglandin F2Α Impurities | Prostaglandin F2Α Impurities, integral to biomedical science, function as essential analytical standards for purity and stability evaluations of prostaglandin-based drugs. These impurities hold a crucial role in rigorous quality control processes for therapies targeting glaucoma, uterine contractility, and various hormonal disorders, thereby safeguarding therapeutic efficacy and safety. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Prostaglandin F2α tromethamine salt | Prostaglandin F2α is a naturally-occurring prostaglandin and potent vasoconstrictor, exhibiting luteolytic activity. Uses: Abortifacient agents, nonsteroidal. Group: Pharmaceutical. CAS No. 38562-01-5. Pack Sizes: 1 g. Product ID: B1370-091489. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 17-Phenyl Trinor Prostaglandin F2α Methyl Amide | 17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is an analog of Bimatoprost, an antiglaucoma agent. Group: Pharmaceutical. CAS No. 155206-01-2. Pack Sizes: 100 mg. Product ID: B2693-336215. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1,1,1-trifluorooctan-2-one | 1,1,1-trifluorooctan-2-one, a powerful chemical compound, is an indispensable ingredient in the manufacture of several pharmaceuticals including prostaglandins. Moreover, it is widely employed in the synthesis of agrochemicals. Scientific experiments have also shown promising results regarding its potent antibacterial and antifungal attributes. Group: Pharmaceutical. CAS No. 400-60-2. Pack Sizes: 250 mg. Product ID: B2699-134526. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 15-Keto Travoprost | One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. CAS No. 404830-45-1. Pack Sizes: 25 mg. Product ID: B1911-313687. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4,4'-DIHYDROXY-2-METHOXYCHALCONE | Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. It was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Group: Pharmaceutical. CAS No. 34221-41-5. Pack Sizes: 10 mg. Product ID: NP0936. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetone 2,4-Dinitrophenylhydrazone-[13C3] | Isotope labelled Acetone 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic ketone found in mainstream cigarette smoke. Acetone 2,4-Dinitrophenylhydrazone showed inhibitory activity towards soybean lipoxygenase and renal prostaglandin synthetase. Group: Pharmaceutical. CAS No. 395075-27-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003209. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetone 2,4-Dinitrophenylhydrazone-[d3] | Labelled Acetone 2,4-Dinitrophenylhydrazone. Acetone 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic ketone found in mainstream cigarette smoke. Acetone 2,4-Dinitrophenylhydrazone showed inhibitory activity towards soybean lipoxygenase and renal prostaglandin synthetase. Group: Pharmaceutical. CAS No. 259824-57-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-013535. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| α-Linolenic acid | α-Linolenic acid (ALA) is an omega-3 fatty acid that occurs as the glyceride in most drying oils. It has an inhibitory effect on prostaglandin thus reduces inflammation and the risk of certain chronic diseases. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 463-40-1. Pack Sizes: 10 g. Product ID: B0005-464656. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| α-Viniferin | α-Viniferin isolated from the herb of Carex humilis Leyss. It inhibits AChE activity is specific, reversible and noncompetitive,down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. Uses: Anti-inflammatory activity; antifungal; inhibits protein kinase c; inhibits prostaglandin h2 synthase carex humilis. Group: Pharmaceutical. CAS No. 62218-13-7. Pack Sizes: 1 mg. Product ID: NP4646. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bimatoprost | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Uses: For research used only. Group: Pharmaceutical. CAS No. 155206-00-1. Pack Sizes: 250 mg. Product ID: B0084-340237. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bimatoprost Impurities | Bimatoprost Impurities, fundamental to pharmaceutical rigor, assume critical roles in maintaining the integrity and safety of bimatoprost formulations. Functioning as prostaglandin analogs, they address conditions such as glaucoma and ocular hypertension, enabling comprehensive analytical profiling and exacting quality control, thereby accentuating their pivotal clinical importance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bismuth Subsalicylate | Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. Uses: Antidiarrheals. Group: Pharmaceutical. CAS No. 14882-18-9. Pack Sizes: 1 kg. Product ID: B1370-059261. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Carboprost tromethamine | Carboprost tromethamine is the salt of Carboprost, an analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha). Carboprost activates prostaglandin F receptor, and causes smooth muscle contractions. Group: Pharmaceutical. CAS No. 58551-69-2. Pack Sizes: 10 mg. Product ID: B0084-094990. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cloprostenol Impurities | Cloprostenol Impurities hold a critical position in the biomedical sector, facilitating the scrutiny and refinement of prostaglandin-derived therapies. These impurities are integral to the synthesis and quality assessment of pharmacological solutions designed for reproductive issues in veterinary contexts, safeguarding therapeutic efficacy and safety for livestock and companion animal care. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cloprostenol sodium | Cloprostenol sodium is a synthetic and water-soluble aryl-oxymethyl analog of prostaglandin F2&alpha. lt is also a potent inhibitor of rat adipose precursor differentiation in primary cultures. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also used for the treatment of infertility in sows and gilts. Uses: Luteolytic agents. Group: Pharmaceutical. CAS No. 55028-72-3. Pack Sizes: 1 g. Product ID: B0084-094301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-Cloprostenol sodium salt | (+)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol, which is an aryl-oxymethyl analog of prostaglandin F2&alpha. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also an FP receptor agonist. Uses: Luteolytic agents. Group: Pharmaceutical. CAS No. 62561-03-9. Pack Sizes: 500 mg. Product ID: B2693-095882. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (±)-Corey lactone diol | (±)-Corey lactone diol is an impurity of lubiprostone, a bicyclic fatty acid metabolite analog of Prostaglandin E1. Group: Pharmaceutical. CAS No. 54423-47-1. Pack Sizes: 100 mg. Product ID: B1105-425510. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diclofenac Potassium | Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Group: Pharmaceutical. CAS No. 15307-81-0. Pack Sizes: 20 g. Product ID: B0084-059596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diosmin | Diosmin is a flavonoid glycoside found in citrus fruits. Diosmin exhibits vasoprotective, anti-inflammatory, free-radical scavenging, and antimutagenic properties via inhibiting prostaglandin E2 and thromboxane A2. It also inhibits the adhesion, migration, and activation of leukocytes at the capillary level. Diosmin can be used in health products. Uses: Vascular protectant. Group: Pharmaceutical. CAS No. 520-27-4. Pack Sizes: 2 kg. Product ID: NP1929. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| E7046 | E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Group: Pharmaceutical. CAS No. 1369489-71-3. Pack Sizes: 50 mg. Product ID: B0084-007670. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grapiprant (CJ-023423) | Grapiprant, also known as CJ-023,423, RQ-00000007 and AAT-007, is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. Group: Pharmaceutical. CAS No. 415903-37-6. Pack Sizes: 10 mg. Product ID: B0084-470919. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GYY-4137 Morpholine salt | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Group: Pharmaceutical. CAS No. 106740-09-4. Pack Sizes: 100 mg. Product ID: B2693-272139. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Latanoprost | Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects. The EC50 value of latanoprost (tested as the free acid) for FP receptors is 3.6 nM. Group: Pharmaceutical. CAS No. 130209-82-4. Pack Sizes: 50 mg. Product ID: B0084-056938. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Latanoprostene Bunod | Latanoproste bunod is a nitric oxide-donating prostaglandin F2α (FP) receptor agonist. Under the trade name Vyzulta, it has been approved for the treatment of intraocular pressure in patients with open-angle glaucoma or ocular hypertension in 2017. Group: Pharmaceutical. CAS No. 860005-21-6. Pack Sizes: 25 mg. Product ID: B2692-291720. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lubiprostone | Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing intestinal fluid secretion. It is used in the management of idiopathic chronic constipation, and irritable bowel syndrome with constipation. Group: Pharmaceutical. CAS No. 136790-76-6. Pack Sizes: 100 mg. Product ID: B0084-057968. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mussaenoside | Mussaenoside is a natural iridoid found in the herbs of Melampyrum roseum Maxim, it can inhibit the release of pro-inflammatory cytokines induced by LPS, the production of nitric oxide (NO) and prostaglandin E2, and the expression of inducible NO synthase and cyclooxygenase-2 induced by lipopolysaccharide (LPS) in the RAW264.7 murine macrophage cell line. Mussaenoside also exhibits the activity of anti-inflammatory. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 64421-27-8. Pack Sizes: 1 mg. Product ID: NP3859. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PF-04418948 | PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. Group: Pharmaceutical. CAS No. 1078166-57-0. Pack Sizes: 50 mg. Product ID: B2693-470809. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Phloretin | Phloretin, a type of natural phenol found in the peels of apples, is a dihydrochalcone that shows beneficial effects on diabetes. Phloretin has whitening, freckle removal, anti-aging, strong antioxidant, and photoprotective effects. It can also inhibit the activity of matrix metalloproteinase (MMP-1) and elastase, which can degrade skin connective tissue and play an important role in the process of skin photoaging. Phloretin has excellent immunosuppressive and anti-inflammatory effects. Phloretin can significantly inhibit the levels of nitrogen oxide, prostaglandin E2, IL-6, TNF-α, iNOS and COX-2, inhibit the nuclear translocation of NF-JB subunit p65 protein, and reduce phosphorylation in the MAPK pathway. It can be used in facial masks, skin creams, lotions and essences. Uses: Antimicrobial activity. Group: Pharmaceutical. CAS No. 60-82-2. Pack Sizes: 100 g. Product ID: NP0981. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rhoifolin | Rhoifolin is a natural flavonoid isolated from the leaves of Turpinia arguya Seem. It may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Rhoifolin inhibits the activity of anti-inflmmatory and increases the total antioxidant capacity in a reverse dose order, which can cause a time and reverse dose dependent reduction of carrageenin-induced rat paw oedema, significantly abrogate prostaglandin E2 level, significantly diminish the TNF-a release in the inflammatory exudates. The compound could also be used as an ideal anticancer agent, and it discriminates between cancerous and non cancerous cell as it kills only the former one, so the side effects which may appear during chemotherapy could be overcome. Uses: Anti-inflammatory; anti-cancer. Group: Pharmaceutical. CAS No. 17306-46-6. Pack Sizes: 25 mg. Product ID: NP1948. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Group: Pharmaceutical. CAS No. 72873-74-6. Pack Sizes: 300 mg. Product ID: B0084-195907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tafluprost | Tafluprost is a novel prostanoid analogue that activates Prostaglandin Receptor. It is used in the treatment of glaucoma and is the first prostanoid to be released in a preservative free-formula. Group: Pharmaceutical. CAS No. 209860-87-7. Pack Sizes: 20 mg. Product ID: B0084-087316. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Travoprost | Travoprost is a potent and selective FP prostaglandin receptor agonist used for the treatment of glaucoma. Group: Pharmaceutical. CAS No. 157283-68-6. Pack Sizes: 100 mg. Product ID: B0084-059917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Travoprost Acid | One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. CAS No. 54276-17-4. Pack Sizes: 10 mg. Product ID: B1370-447705. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Travoprost Impurities | Travoprost Impurities, serving as critical analytical constituents, are indispensable in the nuanced exploration of prostaglandin analogs, underpinning rigorous pharmaceutical quality assurance. Their examination is crucial for validating the safety and therapeutic potency of travoprost compositions, essential for managing ocular conditions like glaucoma and ocular hypertension via intraocular pressure reduction. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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