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Prostaglandin derivative. CAS No. 87007-31-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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Prostaglandin E1
1mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H34O5. CAS No. 745-65-3. Prepack ID : 13337083-1mg. Molecular Weight : 354.48.
Prostaglandin E1
Prostaglandin-E1 is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It can be used as a vasodilator agent increasing peripheral blood flow. Uses: The treatment of erectile dysfunction, vasodilator agent. Group: Pharmaceutical. Alternative Names: l-PGE1; l-Prostaglandin E1; Lipoprost; Liprostin; Minprog; NSC 165559; ONO 1608; PGE-1; Promostan; Prostaglandin E1; Prostandin; Alprostadil; Topiglan; Vasaprostan. U 10136; U-10,136. CAS No. 745-65-3. Pack Sizes: 50 mg. Product ID: B0084-299024. Molecular formula: C20H34O5. Mole weight: 354.48. Custom synthesis is available. Send your inquiries for more information.
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Prostaglandin E2
Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Uses: Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Group: Pharmaceutical. Alternative Names: Dinoprostone; PGE2; Prostin E2; Prepidil; Cervidil; Minprostin E2; l-Prostaglandin E2. CAS No. 363-24-6. Pack Sizes: 100 mg. Product ID: B1370-286161. Molecular formula: C20H32O5. Mole weight: 352.47. Custom synthesis is available. Send your inquiries for more information.
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Prostaglandin F2α tromethamine salt
Prostaglandin F2α is a naturally-occurring prostaglandin and potent vasoconstrictor, exhibiting luteolytic activity. Uses: Abortifacient agents, nonsteroidal. Group: Pharmaceutical. Alternative Names: U 14585; U14585; U-14585; Dinoprost tromethamine salt; Dinolytic; Zinoprost; Prostin F2 alpha. CAS No. 38562-01-5. Pack Sizes: 1 g. Product ID: B1370-091489. Molecular formula: C20H34O5.C4H11NO3. Mole weight: 475.62. Custom synthesis is available. Send your inquiries for more information.
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17-Phenyl Trinor Prostaglandin F2α Methyl Amide
17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is an analog of Bimatoprost, an antiglaucoma agent. Group: Pharmaceutical. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-5-heptenamide; [1R-[1α(Z),2β(1E,3S*),3α,5α]]-7-[3,5-zdihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-N-methyl-5-heptenamide; Bimatoprost Impurity 5. CAS No. 155206-01-2. Pack Sizes: 100 mg. Product ID: B2693-336215. Molecular formula: C24H35NO4. Mole weight: 401.54. Custom synthesis is available. Send your inquiries for more information.
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1,1,1-trifluorooctan-2-one
1,1,1-trifluorooctan-2-one, a powerful chemical compound, is an indispensable ingredient in the manufacture of several pharmaceuticals including prostaglandins. Moreover, it is widely employed in the synthesis of agrochemicals. Scientific experiments have also shown promising results regarding its potent antibacterial and antifungal attributes. Group: Pharmaceutical. Alternative Names: 2-Octanone, 1,1,1-trifluoro-. CAS No. 400-60-2. Pack Sizes: 250 mg. Product ID: B2699-134526. Molecular formula: C8H13F3O. Mole weight: 182.18. Custom synthesis is available. Send your inquiries for more information.
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13-trans-Latanoprost
17-phenyl trinor PGF2α is a potent FP receptor agonist. Group: Pharmaceutical. Alternative Names: Bimatoprost isopropyl ester; 17-phenyl-18,19,20-trinor-prostaglandin F2 alpha-1-isopropyl ester; 17-phenyl-18,19,20-trinor-PGF2alpha-1-isopropyl ester; 13,14-dehydro-latanoprost; Bimatoprost isopropyl ester; 17-phenyl trinor PGF2α-iPr; 17-phenyl trinor PGF2α isopropyl ester; 17-Phenyl trinor Pgf2alpha-Iprdehydrolatanoprost; 17-Phenyl trinor prostaglandin F2α isopropyl ester. CAS No. 130209-76-6. Pack Sizes: 100 mg. Product ID: B2693-072499. Molecular formula: C26H38O5. Mole weight: 430.58. Custom synthesis is available. Send your inquiries for more information.
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15-Keto Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; 15-keto Fluprostenol Isopropyl Ester. CAS No. 404830-45-1. Pack Sizes: 25 mg. Product ID: B1911-313687. Molecular formula: C26H33F3O6. Mole weight: 498.54. Custom synthesis is available. Send your inquiries for more information.
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17-phenyl-trinor-PGF2alpha amide
17-phenyl-trinor-PGF2alpha amide. Group: Pharmaceutical. Alternative Names: 17-phenyl-trinor-PGF2α amide; 17-Phenyl trinor prostaglandin F2alpha amide; 17-Phenyl trinor prostaglandin F2α amide; Bimatoprost amide; N-Desethyl Bimatoprost. CAS No. 155205-89-3. Pack Sizes: 50 mg. Product ID: B1370-072510. Molecular formula: C23H33NO4. Mole weight: 387.52. Custom synthesis is available. Send your inquiries for more information.
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4,4'-DIHYDROXY-2-METHOXYCHALCONE
Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. It was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Group: Pharmaceutical. Alternative Names: (E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; (E)-4,4'-Dihydroxy-2-methoxychalcone; 4,4'-Dihydroxy-2-methoxy-trans-chalcone; 4'-Dihydroxy-2-Methoxychalcone; Retrochalcone. CAS No. 34221-41-5. Pack Sizes: 10 mg. Product ID: NP0936. Molecular formula: C16H14O4. Mole weight: 270.28. Custom synthesis is available. Send your inquiries for more information.
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5,6-trans-Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. Alternative Names: Travoprost 5,6-trans isomer; (5E)-7-[(1R,3R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; Isopropyl (E)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate. CAS No. 1563176-59-9. Pack Sizes: 10 mg. Product ID: B1370-290009. Molecular formula: C26H35F3O6. Mole weight: 500.56. Custom synthesis is available. Send your inquiries for more information.
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5-Trans Bimatoprost
5-Trans Bimatoprost is the trans-isomer used in the improved process for the production and purification of Bimatoprost. Group: Pharmaceutical. Alternative Names: (5E)-BiMatoprost; 5-trans-17-phenyl trinor Prostaglandin F2α ethyl amide; (5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenaMide. CAS No. 1163135-95-2. Pack Sizes: 5 mg. Product ID: B2694-467544. Molecular formula: C25H37NO4. Mole weight: 415.58. Custom synthesis is available. Send your inquiries for more information.
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AAT-008
AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Group: Pharmaceutical. Alternative Names: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. CAS No. 847727-81-5. Pack Sizes: 1mg;1g;10g. Product ID: 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8. Custom synthesis is available. Send your inquiries for more information.
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α-Hydroxy Flurbiprofen
An impurity of Flurbiprofen. Flurbiprofen is a potent nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class (like ibuprofen). It exhibits analgesic, anti-inflammatory, and antipyretic effects by inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Group: Pharmaceutical. Alternative Names: Flurbiprofen Impurity C; (2RS)-2-(2-Fluoro[1,1'-biphenyl]-4-yl)-2-hydroxypropanoic acid; (2RS)-2-(2-Fluorobiphenyl-4-yl)-2-hydroxypropanoic Acid; 2-(2-Fluorobiphenyl-4-yl)-2-hydroxypropanoic acid; 2-(2-Fluoro-[1,1'-biphenyl]-4-yl)-2-hydroxypropanoic acid; 2-Fluoro-α-hydroxy-α-methyl[1,1'-biphenyl]-4-acetic acid; 2-(2-Fluoro-4-biphenyl)-2-hydroxypropionic acid; Flurbiprofen EP Impurity C. CAS No. 61466-95-3. Pack Sizes: 250 mg. Product ID: B0965-471758. Molecular formula: C15H13FO3. Mole weight: 260.27. Custom synthesis is available. Send your inquiries for more information.
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α-Linolenic acid
α-Linolenic acid (ALA) is an omega-3 fatty acid that occurs as the glyceride in most drying oils. It has an inhibitory effect on prostaglandin thus reduces inflammation and the risk of certain chronic diseases. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: alpha-Linolenic acid; linolenic acid; linolenate; Octadeca-9Z,12Z,15Z-Trienoic acid; (Z,Z,Z)-9,12,15-Octadecatrienoic acid; 9,12,15-Octadecatrienic acid; 9,12,15-Octadecatrienoic acid; 9Z,12Z,15Z-Octadecatrienoic acid; alpha-LNN; all cis-9,12,15-Octadecatrienoic acid. CAS No. 463-40-1. Pack Sizes: 10 g. Product ID: B0005-464656. Molecular formula: C18H30O2. Mole weight: 278.43. Custom synthesis is available. Send your inquiries for more information.
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α-Viniferin
α-Viniferin isolated from the herb of Carex humilis Leyss. It inhibits AChE activity is specific, reversible and noncompetitive,down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. Uses: Anti-inflammatory activity; antifungal; inhibits protein kinase c; inhibits prostaglandin h2 synthase carex humilis. Group: Pharmaceutical. Alternative Names: (+)-α-viniferin. CAS No. 62218-13-7. Pack Sizes: 1 mg. Product ID: NP4646. Molecular formula: C42H30O9. Mole weight: 678.7. Custom synthesis is available. Send your inquiries for more information.
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Angoroside C
Angoroside C is an anti-inflammatory compound isolated from the roots of Scrophularia ningpoensis Hemsl. Angoroside C acts as an inhibitor of prostaglandin E2 release in mice. Group: Pharmaceutical. Alternative Names: 2-(3-hydroxy-4-methoxyphenyl)ethyl alpha-L-arabinopyranosyl-(1->6)-[6-deoxy-alpha-L-talopyranosyl-(1->3)]-4-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside. CAS No. 115909-22-3. Pack Sizes: 1mg;1g;10g. Product ID: NP5201. Molecular formula: C36H48O19. Mole weight: 784.77. Custom synthesis is available. Send your inquiries for more information.
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Benzydamine hydrochloride
Benzydamine hydrochlorid is structurally unrelated to the corticosteroids. The action of benzydamine may be mediated by the prostaglandin system. Uses: Anti-inflammatory agents. Group: Pharmaceutical. Alternative Names: AF864; AF 864; AF-864; Benzydamine HCl; Benzidamine hydrochloride; Benzindamine hydrochloride; {3-[(1-benzyl-1H-indazol-3-yl)oxy]propyl}dimethylamine hydrochloride; 3-((1-Benzyl-1H-indazol-3-yl)oxy)-N,N-dimethylpropan-1-amine hydrochloride; 1-Propanamine, N,N-dimethyl-3-((1-(phenylmethyl)-1H-indazol-3-yl)oxy)-, monohydrochloride; 1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole hydrochloride. CAS No. 132-69-4. Pack Sizes: 1mg;1g;10g. Product ID: NP2775. Molecular formula: C19H23N3O.HCl. Mole weight: 345.87. Custom synthesis is available. Send your inquiries for more information.
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Bimatoprost
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Uses: For research used only. Group: Pharmaceutical. Alternative Names: AGN 192024; AGN192024; AGN-192024; Bimatoprost; Lumigan; Latisse; Bimatoprostum; Lumigan. CAS No. 155206-00-1. Pack Sizes: 250 mg. Product ID: B0084-340237. Molecular formula: C25H37NO4. Mole weight: 415.57. Custom synthesis is available. Send your inquiries for more information.
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Bismuth Subsalicylate
Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. Uses: Antidiarrheals. Group: Pharmaceutical. Alternative Names: Bismuth oxysalicylate; Bismuth oxide salicylate; Wismutsubsalicylat; Bismuth(III) subsalicylate. CAS No. 14882-18-9. Pack Sizes: 1 kg. Product ID: B1370-059261. Molecular formula: C7H5BiO4. Mole weight: 362.09. Custom synthesis is available. Send your inquiries for more information.
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Carboprost tromethamine
Carboprost tromethamine is the salt of Carboprost, an analogue of naturally occurring prostaglandin F2 alpha (PGF2 alpha). Carboprost activates prostaglandin F receptor, and causes smooth muscle contractions. Group: Pharmaceutical. Alternative Names: Hemabate; Carboprost Trometanol; 2-amino-2-(hydroxymethyl)propane-1,3-diol;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid. CAS No. 58551-69-2. Pack Sizes: 10 mg. Product ID: B0084-094990. Molecular formula: C25H47NO8. Mole weight: 489.65. Custom synthesis is available. Send your inquiries for more information.
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Chebulagic acid
Chebulagic acid is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities. It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. And it can also inhibit the production of NO, prostaglandin E2 (PGE2), and reactive oxygen species (ROS), and nuclear translocation of NF-κB in RAW 264.7 macrophages in a concentration-dependent manner. Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Uses: Topoisomerase i inhibitors. Group: Pharmaceutical. Alternative Names: β-D-glucopyranose; Cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate); Cyclic 2→2:4→1-ester with (2S)-2-[(3S,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid. CAS No. 23094-71-5. Pack Sizes: 50 mg. Product ID: B1370-300064. Molecular formula: C41H30O27. Mole weight: 954.66. Custom synthesis is available. Send your inquiries for more information.
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Cloprostenol sodium
Cloprostenol sodium is a synthetic and water-soluble aryl-oxymethyl analog of prostaglandin F2α. lt is also a potent inhibitor of rat adipose precursor differentiation in primary cultures. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also used for the treatment of infertility in sows and gilts. Uses: Luteolytic agents. Group: Pharmaceutical. Alternative Names: ICI 80996; ICI-80996; ICI 80996; ICI 80,996; ICI-80,996; ICI 80,996; DL-Cloprostenol sodium; Estroplan; Estrumate;DL-Cloprostenol sodium;Estroplan;Estrumate;sodium (Z)-7-(2-((E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate;5-Heptenoicacid,7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-. CAS No. 55028-72-3. Pack Sizes: 1 g. Product ID: B0084-094301. Molecular formula: C22H28ClNaO6. Mole weight: 446.9. Custom synthesis is available. Send your inquiries for more information.
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(+)-Cloprostenol sodium salt
(+)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol, which is an aryl-oxymethyl analog of prostaglandin F2α. It has luteolytic effects and is used for the synchronization of estrus in cattle. It is also an FP receptor agonist. Uses: Luteolytic agents. Group: Pharmaceutical. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt; [1R-[1α(Z),2β(1E,3R*),3α,5α]]- 7-[2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid Sodium Salt. CAS No. 62561-03-9. Pack Sizes: 500 mg. Product ID: B2693-095882. Molecular formula: C22H28ClO6Na. Mole weight: 446.9. Custom synthesis is available. Send your inquiries for more information.
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(±)-Corey lactone diol
(±)-Corey lactone diol is an impurity of lubiprostone, a bicyclic fatty acid metabolite analog of Prostaglandin E1. Group: Pharmaceutical. Alternative Names: (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. CAS No. 54423-47-1. Pack Sizes: 100 mg. Product ID: B1105-425510. Molecular formula: C8H12O4. Mole weight: 172.18. Custom synthesis is available. Send your inquiries for more information.
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Diclofenac Potassium
Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Group: Pharmaceutical. Alternative Names: 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Potassium Salt; [o-(2,6-Dichloroanilino)phenyl]acetic Acid Monopotassium Salt; 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monopotassium Salt; Caflam; Cataflam; K-fenak; Potassium diclofenac. CAS No. 15307-81-0. Pack Sizes: 20 g. Product ID: B0084-059596. Molecular formula: C14H10Cl2KNO2. Mole weight: 334.24. Custom synthesis is available. Send your inquiries for more information.
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Dinoprost
Dinoprost is a widely distributed PG occurring in many species, causing contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. Group: Pharmaceutical. Alternative Names: Prostaglandin F2α; prostaglandin F2alpha; HSDB3315; HSDB-3315; HSDB 3315. CAS No. 551-11-1. Pack Sizes: 1 g. Product ID: B2693-071360. Molecular formula: C20H34O5. Mole weight: 354.49. Custom synthesis is available. Send your inquiries for more information.
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Diosmin
Diosmin is a flavonoid glycoside found in citrus fruits. Diosmin exhibits vasoprotective, anti-inflammatory, free-radical scavenging, and antimutagenic properties via inhibiting prostaglandin E2 and thromboxane A2. It also inhibits the adhesion, migration, and activation of leukocytes at the capillary level. Diosmin can be used in health products. Uses: Vascular protectant. Group: Pharmaceutical. Alternative Names: 7-[6-O-Deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3',5,7-Trihydroxy-4'-methoxyflavone 7-rutinoside; Diosmetin 7-b-rutinoside. CAS No. 520-27-4. Pack Sizes: 2 kg. Product ID: NP1929. Molecular formula: C28H32O15. Mole weight: 608.54. Custom synthesis is available. Send your inquiries for more information.
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E7046
E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Group: Pharmaceutical. Alternative Names: E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid. CAS No. 1369489-71-3. Pack Sizes: 50 mg. Product ID: B0084-007670. Molecular formula: C22H18F5N3O4. Mole weight: 483.39. Custom synthesis is available. Send your inquiries for more information.
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Fenprostalene
Fenprostalene is a long-acting prostaglandin F2 alpha analog. It is indicated for the use in feedlot heifers to induce abortion when pregnant 150 days or less, for the induction of parturition in sows and gilts pregnant at least 112 days. Group: Pharmaceutical. Alternative Names: Bovilene; Fenprostalene; Synchrocept B (Veterinary); methyl 7-[(1S,2S,3S,5R)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-4-phenoxybut-1-enyl]cyclopentyl]hepta-4,5-dienoate. CAS No. 69381-94-8. Pack Sizes: 1mg;1g;10g. Product ID: 69381-94-8. Molecular formula: C23H30O6. Mole weight: 402.487. Custom synthesis is available. Send your inquiries for more information.
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Feprazone
Feprazone: A nonsteroidal anti-inflammatory drug (NSAID) utilized in the alleviation of pain and inflammation linked to various conditions like arthritis, menstrual cramps, and musculoskeletal disorders. It operates through the suppression of prostaglandins, biological compounds responsible for the onset of pain and inflammation. Group: Pharmaceutical. CAS No. 30748-29-9. Pack Sizes: 1mg;1g;10g. Product ID: 30748-29-9. Molecular formula: C20H20N2O2. Mole weight: 320.39. Custom synthesis is available. Send your inquiries for more information.
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Flurbiprofen
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class. It exerts analgesic, anti-inflammatory, and antipyretic effects by reversibly inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Clinically, it is used to manage pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and postoperative discomfort. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid; (±)-Flurbiprofen; 2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid; 2-(2-Fluoro-4-biphenyl)propionic acid; 2-(2-Fluoro-4-biphenylyl)propanoic acid; 2-(2-Fluoro-4-biphenylyl)propionic acid; 2-Fluoro-α-methyl-4-biphenylacetic acid; 2-Fluoro-α-methyl-4-diphenylacetic acid; 3-Fluoro-4-phenylhydratropic acid; Adfeed; Ansaid; Antadys; BTS 18322; Cebutid; dl-2-(2-Fluoro-4-biphenylyl)propionic acid; dl-Flurbiprofen; Flugalin; Flurbifen; Fluribiprofen; Fluroben; Flurofen; FP 70; FP-A; Froben; rac-Flurbiprofen; Racemic flurbiprofen; Stayban; Synalgo; U 27182; Urbifen; Zepolas. CAS No. 5104-49-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04023. Molecular formula: C15H13FO2. Mole weight: 244.26. Custom synthesis is available. Send your inquiries for more information.
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Flurbiprofen Sodium
Flurbiprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) derived from propionic acid. It functions as a potent inhibitor of cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Group: Pharmaceutical. Alternative Names: [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, sodium salt (1:1); 2-(2-Fluorobiphenyl-4-yl)propionic acid sodium salt; 2-Fluoro-α-methyl-4-diphenylacetic acid sodium salt; Flurbiprofen sodium salt; Ocufen; Ocuflur; Sodium 3-fluoro-4-phenylhydratropate; Sodium flurbiprofen. CAS No. 56767-76-1. Pack Sizes: 5 g. Product ID: BBF-03906. Molecular formula: C15H12FNaO2. Mole weight: 266.24. Custom synthesis is available. Send your inquiries for more information.
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Grapiprant (CJ-023423)
Grapiprant, also known as CJ-023,423, RQ-00000007 and AAT-007, is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. Group: Pharmaceutical. Alternative Names: CJ-023423; CJ 023423; CJ023423; CAS#415903-37-6; RQ-00000007; RQ 00000007; RQ00000007; AAT-007; AAT007; AAT 007; Grapiprant. CAS No. 415903-37-6. Pack Sizes: 10 mg. Product ID: B0084-470919. Molecular formula: C26H29N5O3S. Mole weight: 491.61. Custom synthesis is available. Send your inquiries for more information.
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GYY-4137 Morpholine salt
GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Group: Pharmaceutical. Alternative Names: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;ZYJ1122 morpholine salt;ZYJ-1122 morpholine salt. CAS No. 106740-09-4. Pack Sizes: 100 mg. Product ID: B2693-272139. Molecular formula: C15H25N2O3PS2. Mole weight: 376
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Ketoprofen
Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin. Group: Pharmaceutical. Alternative Names: RP-19583; RP 19583; RP19583. CAS No. 22071-15-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3621. Molecular formula: C16H14O3. Mole weight: 254.28. Custom synthesis is available. Send your inquiries for more information.
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Latanoprost
Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects. The EC50 value of latanoprost (tested as the free acid) for FP receptors is 3.6 nM. Group: Pharmaceutical. Alternative Names: PHXA41; PHXA-41; PHXA 41; XA34; XA-34; XA 34; Latanoprost, Xalatan, Catioprost. CAS No. 130209-82-4. Pack Sizes: 50 mg. Product ID: B0084-056938. Molecular formula: C26H40O5. Mole weight: 432.59. Custom synthesis is available. Send your inquiries for more information.
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Latanoprostene Bunod
Latanoproste bunod is a nitric oxide-donating prostaglandin F2α (FP) receptor agonist. Under the trade name Vyzulta, it has been approved for the treatment of intraocular pressure in patients with open-angle glaucoma or ocular hypertension in 2017. Group: Pharmaceutical. Alternative Names: BOL-303259-X; NCX 116; PF-3187207. CAS No. 860005-21-6. Pack Sizes: 25 mg. Product ID: B2692-291720. Molecular formula: C27H41NO8. Mole weight: 507.62. Custom synthesis is available. Send your inquiries for more information.
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Loxoprofen
Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic Acid; 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic Acid; 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid. CAS No. 68767-14-6. Pack Sizes: 1mg;1g;10g. Product ID: NP3266. Molecular formula: C15H18O3. Mole weight: 246.3. Custom synthesis is available. Send your inquiries for more information.
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Lubiprostone
Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing intestinal fluid secretion. It is used in the management of idiopathic chronic constipation, and irritable bowel syndrome with constipation. Group: Pharmaceutical. Alternative Names: Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-; (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid; RU 0211. CAS No. 136790-76-6. Pack Sizes: 100 mg. Product ID: B0084-057968. Molecular formula: C20H32F2O5. Mole weight: 390.47. Custom synthesis is available. Send your inquiries for more information.
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Mussaenoside
Mussaenoside is a natural iridoid found in the herbs of Melampyrum roseum Maxim, it can inhibit the release of pro-inflammatory cytokines induced by LPS, the production of nitric oxide (NO) and prostaglandin E2, and the expression of inducible NO synthase and cyclooxygenase-2 induced by lipopolysaccharide (LPS) in the RAW264.7 murine macrophage cell line. Mussaenoside also exhibits the activity of anti-inflammatory. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: (1S,7S)-1-(β-D-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-7-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester. CAS No. 64421-27-8. Pack Sizes: 1 mg. Product ID: NP3859. Molecular formula: C17H26O10. Mole weight: 390.4. Custom synthesis is available. Send your inquiries for more information.
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PF-04418948
PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. Group: Pharmaceutical. Alternative Names: PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948. CAS No. 1078166-57-0. Pack Sizes: 50 mg. Product ID: B2693-470809. Molecular formula: C23H20FNO5. Mole weight: 409.41. Custom synthesis is available. Send your inquiries for more information.
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Phloretin
Phloretin, a type of natural phenol found in the peels of apples, is a dihydrochalcone that shows beneficial effects on diabetes. Phloretin has whitening, freckle removal, anti-aging, strong antioxidant, and photoprotective effects. It can also inhibit the activity of matrix metalloproteinase (MMP-1) and elastase, which can degrade skin connective tissue and play an important role in the process of skin photoaging. Phloretin has excellent immunosuppressive and anti-inflammatory effects. Phloretin can significantly inhibit the levels of nitrogen oxide, prostaglandin E2, IL-6, TNF-α, iNOS and COX-2, inhibit the nuclear translocation of NF-JB subunit p65 protein, and reduce phosphorylation in the MAPK pathway. It can be used in facial masks, skin creams, lotions and essences. Uses: Antimicrobial activity. Group: Pharmaceutical. Alternative Names: Dihydronaringenin; NSC 407292; NSC-407292; NSC407292; RJC 02792; RJC02792; RJC-02792; 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone; Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-; 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone; 2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone; Dihydronaringenin; Naringenin dihydrochalcone; NSC 407292; Phloretol; RJC 02792; α,β-Dihy. CAS No. 60-82-2. Pack Sizes: 100 g. Product ID: NP0981. Molecular formula: C15H14O5. Mole weight: 274.27. Custom synthesis is available. Send your inquiries for more informatio
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Rhoifolin
Rhoifolin is a natural flavonoid isolated from the leaves of Turpinia arguya Seem. It may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Rhoifolin inhibits the activity of anti-inflmmatory and increases the total antioxidant capacity in a reverse dose order, which can cause a time and reverse dose dependent reduction of carrageenin-induced rat paw oedema, significantly abrogate prostaglandin E2 level, significantly diminish the TNF-a release in the inflammatory exudates. The compound could also be used as an ideal anticancer agent, and it discriminates between cancerous and non cancerous cell as it kills only the former one, so the side effects which may appear during chemotherapy could be overcome. Uses: Anti-inflammatory; anti-cancer. Group: Pharmaceutical. Alternative Names: Rhoifoloside; Apigenin 7-O-neohesperidoside; Apigenin-7-O-rhamnoglucoside. CAS No. 17306-46-6. Pack Sizes: 25 mg. Product ID: NP1948. Molecular formula: C27H30O14. Mole weight: 578.52. Custom synthesis is available. Send your inquiries for more information.
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SKF-86002
SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Group: Pharmaceutical. Alternative Names: SKF-86002; SKF 86002; SKF86002. 6-(4-fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole; 4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene. CAS No. 72873-74-6. Pack Sizes: 300 mg. Product ID: B0084-195907. Molecular formula: C16H12FN3S. Mole weight: 297.36. Custom synthesis is available. Send your inquiries for more information.
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Tafluprost
Tafluprost is a novel prostanoid analogue that activates Prostaglandin Receptor. It is used in the treatment of glaucoma and is the first prostanoid to be released in a preservative free-formula. Group: Pharmaceutical. Alternative Names: AFP-168, AFP-168, AFP-168, MK-2452, MK2452, MK 2452, Taflotan; Zioptan; AFP-168; Saflutan; propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate. CAS No. 209860-87-7. Pack Sizes: 20 mg. Product ID: B0084-087316. Molecular formula: C25H34F2O5. Mole weight: 452.539. Custom synthesis is available. Send your inquiries for more information.
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Travoprost
Travoprost is a potent and selective FP prostaglandin receptor agonist used for the treatment of glaucoma. Group: Pharmaceutical. Alternative Names: Travatan; Fluprostenol isopropyl ester; AL-6221; Flu-Ipr. CAS No. 157283-68-6. Pack Sizes: 100 mg. Product ID: B0084-059917. Molecular formula: C26H35F3O6. Mole weight: 500.55. Custom synthesis is available. Send your inquiries for more information.
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Travoprost Acid
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid; (+)-Fluprostenol; [1R-[1α(Z),2β(1E,3R*),3α,5α]]-7-[3,5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid; AL 5848; 16-(m-Trifluoromethylphenoxy)-17,18,19,20-tetranorprostaglandin F2α. CAS No. 54276-17-4. Pack Sizes: 10 mg. Product ID: B1370-447705. Molecular formula: C23H29F3O6. Mole weight: 458.48. Custom synthesis is available. Send your inquiries for more information.
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Tylvalosin
Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Group: Pharmaceutical. Alternative Names: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. CAS No. 63409-12-1. Pack Sizes: 10 mg. Product ID: BBF-05837. Molecular formula: C53H87NO19. Mole weight: 1042.25. Custom synthesis is available. Send your inquiries for more information.
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Unoprostone isopropyl ester
Unoprostone isopropyl ester is the prodrug of unoprostone, an analog of prostaglandin F2α (PGF2α). Unoprostone isopropyl ester, under the brand name Rescula, have been approved for the treatment of ocular hypertension. Group: Pharmaceutical. Alternative Names: 13,14-dihydro-15-keto-20-ethyl Prostaglandin F2α isopropyl ester; Rescula. CAS No. 120373-24-2. Pack Sizes: 1mg;1g;10g. Product ID: 120373-24-2. Molecular formula: C25H44O5. Mole weight: 424.6. Custom synthesis is available. Send your inquiries for more information.
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URB937
URB937 is a potent, peripheral fatty acid amide hydrolase (FAAH) inhibitor with IC50 value of 26.8 nM. It was shown to reduce prostaglandin E2-induced bladder overactivity and hyperactivity of bladder mechano-afferent nerve fibers in rats. Group: Pharmaceutical. Alternative Names: URB-937; URB 937; 3'-carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate; cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester. CAS No. 1357160-72-5. Pack Sizes: 100 mg. Product ID: B1370-008861. Molecular formula: C20H22N2O4. Mole weight: 354.4. Custom synthesis is available. Send your inquiries for more information.
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