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| Product | Description | |
|---|---|---|
| Proguanil hydrochloride | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics, Testing Standards. Formula: C11H15Cl2N5. CAS No. 537-21-3. Prepack ID : 10785411-25mg. Molecular Weight : 288.18. |  |
| Proguanil hydrochloride | Proguanil hydrochloride is the hydrochloride salt form of proguanil, which is a synthetic biguanide derivative of pyrimidine. It is used as an folate antagonist with antimalarial property. It is used to treat and prevent malaria together with chloroquine or atovaquone. lt is converted by the liver to its active metabolite, cycloguanil. It may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. It was developed by AstraZeneca and has been listed. Uses: Proguanil hydrochloride is used as an folate antagonist with antimalarial property. Group: Pharmaceutical. Alternative Names: 1-(p-chlorophenyl)-5-isopropylbiguanidehydrochloride; 1-(p-chlorophenyl)-5-isopropyl-biguanidmonohydrochloride; 3359rp; chlorguanidehydrochloride; chloroguanidehydrochloride; chloroguanidinehydrochloride; diguanyl; drinupalhydrochloride. CAS No. 637-32-1. Pack Sizes: 1mg;1g;10g. Product ID: 637-32-1. Molecular formula: C11H17Cl2N5. Mole weight: 290.19. Custom synthesis is available. Send your inquiries for more information. |  London |
| Cycloguanil hydrochloride | Cycloguanil is an active metabolite of proguanil, produced by the cytochrome P450 2C19 isoform. It is also an inhibitor of dihydrofolate reductase (DHFR) (Kis = 0.3 and 1.5 nM for Plasmodium and human forms, respectively). Uses: Antimalarials. Group: Pharmaceutical. Alternative Names: Chloroguanide Triazine; NSC 3074; 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine monohydrochloride. CAS No. 152-53-4. Pack Sizes: 500 mg. Product ID: B2693-118548. Molecular formula: C11H14ClN5·HCl. Mole weight: 288.2. Custom synthesis is available. Send your inquiries for more information. | London |
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