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Procyanidin A1 Procyanidin A1 is found in cinnamon and is extracted from the herbs of Daemonorops draco. It is an epicatechin-(2β→7,4β→8)-catechin dimer and is potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone. It inhibits LDL oxidation with the IC50 value of 0.94 uM. It also inhibits degranulation downstream of protein kinase C activation or Ca2? influx from an internal store in RBL-2H3 cells. It shows antiallergic effects. Group: Pharmaceutical. Alternative Names: Proanthocyanidin A1; Epicatechin-(2b->7,4b->8)-catechin; (2R,3S,8S,14R,15R)-2,8-Bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol. CAS No. 103883-03-0. Pack Sizes: 25 mg. Product ID: NP1979. Molecular formula: C30H24O12. Mole weight: 576.5. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Procyanidin C1 Procyanidin C1 is extracted from the fruits of Vitis vinifera L. It is a B type proanthocyanidin and found in grape. It belongs to a polyphenol flavonoid epicatechin trimer. It can decrease cytokine production of mast cells and Fc epsilon RI-mediated degranulation in vitro dose-dependently. It inhibits ROS generation in stimulated mast cells and the tyrosine phosphorylation of Syk and linker for activation of T cells. It may be used for the treatment of cardiovascular diseases and may be useful as a lead compound to develop inhibitors of cancer metastasis and other diseases related to EMT. It has HIV-related, antioxidant and anti-inflammatory effects. It also inhibits the activity of 15-lipoxygenase and α-glucosidase. It could scavenge 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radicals. Group: Pharmaceutical. Alternative Names: Procyanidol C1; (2R,2'R,2''R,3R,3'R,3''R,4R,4'S)-2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-[4,8':4',8''-ter-2H-1-benzopyran]-3,3',3'',5,5',5'',7,7',7''-nonol; Proanthocyanidin C1; Cinnamtannin A1; [Epicatechin-(4beta->8)]2-epicatechin. CAS No. 37064-30-5. Pack Sizes: 10 mg. Product ID: NP1983. Molecular formula: C45H38O18. Mole weight: 866.77. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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