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| Product | Description | |
|---|---|---|
| 2-[2,6-Dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid | 2-[2,6-Dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid is a racemic compound of Elafibranor, a dual PPARα/δ agonist that has demonstrated efficacy in disease models of nonalcoholic fatty liver disease (NAFLD)/NASH and liver fibrosis. Group: Pharmaceutical. Alternative Names: Propanoic acid, 2-[2,6-dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; Propanoic acid, 2-[2,6-dimethyl-4-[3-[4-(methylthio)phenyl]-3-oxo-1-propenyl]phenoxy]-2-methyl-; 1-(4-Methylthiophenyl)-3-[3,5-dimethyl-4-[(carboxydimethylmethyl)oxy]phenyl]prop-2-en-1-one. CAS No. 824932-88-9. Pack Sizes: 50 mg. Product ID: B0084-474857. Molecular formula: C22H24O4S. Mole weight: 384.49. Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a potential PPAR agonist with antibacterial, antidiabetic and antioxidant activities. The esteemed 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a highly efficacious agent utilized in the management of type 2 diabetes mellitus. By enhancing insulin secretion and suppressing hepatic glucose output, it diligently lowers blood glucose concentrations, thereby promoting normoglycemia. Its demonstrated efficacy and mechanism of action render it an alluring therapeutic option for those with the aforementioned condition. Group: Pharmaceutical. Alternative Names: NSC 31150; Antimicrobial agent-33. CAS No. 51244-45-2. Pack Sizes: 50 mg. Product ID: B0001-284765. Molecular formula: C10H5Cl2NO2S. Mole weight: 274.115. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione | 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione is an impurity of Pioglitazone, a PPAR agonist that has antidiabetic activity in patients with type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione; 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-1,3-thiazolidine-2,4-dione; 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzylidene]thiazolidine-2,4-dione. CAS No. 144809-28-9. Pack Sizes: 100 mg. Product ID: NP3434. Molecular formula: C19H18N2O3S. Mole weight: 354.42. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione | 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione, a well-researched organic compound, exhibits remarkable promise in treating diabetes mellitus type 2 owing to its ability to function as an agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ). PPAR-γ is implicated in the modulation of glucose and lipid metabolism. Beyond its anti-diabetic attributes, this compound has been the subject of inquiry for its potential anti-cancer properties. The chemical's therapeutic significance is evidenced by the numerous investigations conducted on its biological activity. Group: Pharmaceutical. Alternative Names: 5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[(4-chlorophenyl)methylene]-. CAS No. 24138-83-8. Pack Sizes: 50 mg. Product ID: B0001-284763. Molecular formula: C10H6ClNO2S. Mole weight: 239.673. Custom synthesis is available. Send your inquiries for more information. | London |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Group: Pharmaceutical. Alternative Names: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E)-1-[4-(Methylthio)phenyl]-3-[3,5-dimethyl-4-[(carboxydimethylmethyl)oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. CAS No. 923978-27-2. Pack Sizes: 250 mg. Product ID: B0084-074234. Molecular formula: C22H24O4S. Mole weight: 384.49. Custom synthesis is available. Send your inquiries for more information. | London |
| GW0742 | GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ. Group: Pharmaceutical. Alternative Names: GW0742; GW-0742; GW 0742; GW0742X; GW-0742X; GW 0742X; GW610742; GW-610742; GW 610742. CAS No. 317318-84-6. Pack Sizes: 50 mg. Product ID: B0084-178999. Molecular formula: C21H17F4NO3S2. Mole weight: 471.49. Custom synthesis is available. Send your inquiries for more information. | London |
| GW1929 | A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays). Group: Pharmaceutical. Alternative Names: GW 1929; GW-1929. CAS No. 196808-24-9. Pack Sizes: 50 mg. Product ID: B2693-196515. Molecular formula: C30H29N3O4. Mole weight: 495.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Hydroxy Pioglitazone-[d4] (M-IV) | Hydroxy Pioglitazone-[d4] (M-IV) is the labelled analogue of Hydroxy Pioglitazone (M-IV), which is a metabolite of Pioglitazone, a PPARγ agonist used as an anti-diabetic drug. Group: Pharmaceutical. Alternative Names: Hydroxy Pioglitazone-d4 (M-IV); 5-[[4-[2-[5-(1-Hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione-d4. CAS No. 1188263-49-1. Pack Sizes: 1 mg. Product ID: BLP-008210. Molecular formula: C19H16D4N2O4S. Mole weight: 376.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Isosilybin A | Isosilybin A is a flavonoid found in Silybum marianum. Isosilybin A has been identified as the first flavonolignan PPAR-gamma agonist. Group: Pharmaceutical. Alternative Names: Isosilibinin A; (+)-Isosilybin A; Silybin b2. CAS No. 142796-21-2. Pack Sizes: 10 mg. Product ID: B2703-362207. Molecular formula: C25H22O10. Mole weight: 482.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Lanifibranor | Lanifibranor is a peroxisome proliferator-activated receptors (PPAR) agonist. Group: Pharmaceutical. Alternative Names: Lanifibranor; IVA-337; IVA 337; IVA337; CPD1537; CPD 1537; CPD-1537; 5-Chloro-1-((6-benzothiazolyl)sulfonyl)-1H-indole-2-butanoic acid. CAS No. 927961-18-0. Pack Sizes: 25 mg. Product ID: B0084-260291. Molecular formula: C19H15ClN2O4S2. Mole weight: 434.909. Custom synthesis is available. Send your inquiries for more information. | London |
| Pioglitazone | Pioglitazone is a PPAR agonist that exhibits antidiabetic activity in patients with type 2 diabetes mellitus. It has no effect on type 1 diabetes. Group: Pharmaceutical. Alternative Names: 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione. CAS No. 111025-46-8. Pack Sizes: 5 g. Product ID: B0084-081675. Molecular formula: C19H20N2O3S. Mole weight: 356.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Pioglitazone EP Impurity A | Pioglitazone EP Impurity A is an impurity of Pioglitazone, a PPAR agonist that has antidiabetic activity in patients with type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: (5RS)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]-phenyl]methyl]-5-hydroxythiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-5-hydroxy-; Pioglitazone Impurity A; 5-Hydroxy Pioglitazone Impurity; Pioglitazone 5-Hydroxy Metabolite; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-5-hydroxy-2,4-thiazolidinedione; 5-Hydroxy pioglitazone; Pioglitazone hydrochloride impurity A [EP]; Hydroxypioglitazone; 5-Hydroxypioglitazone; (±)-5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-5-hydroxythiazolidine-2,4-dione. CAS No. 625853-74-9. Pack Sizes: 10 mg. Product ID: B2694-262097. Molecular formula: C19H20N2O4S. Mole weight: 372.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Pterostilbene | Pterostilbene is a natural plant anti-aging hormone. Pterostilbene has rich medicinal value and belongs to an antifungal active ingredient in blood products. Pterostilbene, a methylated derivative of resveratrol, has many biological activities such as whitening, anti-aging, anti-fungal, anti-oxidation, anti-tumor, hypolipidemia and antibacterial. Pterostilbene is a peroxisome proliferator-activated receptor alpha (PPAR-alpha) agonist. It is an antioxidant component of blueberries and Pterocarpus marsupium. Pterostilbene is a good functional cosmetics material. It is suitable for anti-aging, wrinkle removal, skin rejuvenation, sunscreen repair and relief, anti-inflammatory, antibacterial and analgesic, whitening, freckle removal, brightening, hair care, weight loss and other products, and it is compatible with lotion cream formula, gel formula and water formula. Group: Pharmaceutical. Alternative Names: 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol; 4-Stilbenol, 3',5'-dimethoxy-, (E)-; Phenol, 4-[2-(3,5-dimethoxyphenyl)ethenyl]-, (E)-; (E)-2-(3,5-Dimethoxyphenyl)-1-(4-hydroxyphenyl)ethene; (E)-4-(3,5-Dimethoxystyryl)phenol; (E)-4-Hydroxy-3',5'-dimethoxystilbene; 3,5-Dimethoxy-4'-hydroxy-trans-stilbene; E-Pterostilbene; P 1499; Pterostilbene; trans-3,5-Dimethoxy-4'-hydroxystilbene; trans-Pterostil. CAS No. 537-42-8. Pack Sizes: 100 g. Product ID: NP5199. Molecular formula: C16H16O3. Mole weight: 256.3. Custom synthesis is ava | London |
| Saroglitazar | Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment of diabetic dyslipidemia and hypertriglyceridemia with Type 2 diabetes mellitus not controlled by statin therapy. Group: Pharmaceutical. Alternative Names: Lipaglyn; ZY-H1; (αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic Acid. CAS No. 495399-09-2. Pack Sizes: 10 mg. Product ID: B1370-475759. Molecular formula: C25H29NO4S. Mole weight: 439.57. Custom synthesis is available. Send your inquiries for more information. | London |
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