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| Product | Description | |
|---|---|---|
| 1-NA-PP1 | 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. Group: Pharmaceutical. Alternative Names: 1-(Tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-Naphthyl PP1. CAS No. 221243-82-9. Pack Sizes: 25 mg. Product ID: B2693-102805. Molecular formula: C19H19N5. Mole weight: 317.39. Custom synthesis is available. Send your inquiries for more information. |  London |
| DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS | DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS. Group: Pharmaceutical. Alternative Names: DABCYL-Lys-pp1ab (3235-3246)-Glu-EDANS (Human coronavirus) (strain SARS); DABCYL-Lys-ORF1AB (3235-3246)-Glu-EDANS (Human coronavirus) (strain SARS). CAS No. 730985-86-1. Pack Sizes: 5 mg. Product ID: BAT-014236. Molecular formula: C95H141N25O24S2. Mole weight: 2081.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt. CAS No. 87860-39-7. Pack Sizes: 1 mg. Product ID: B1370-381555. Molecular formula: C19H26O9PNa. Mole weight: 452.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Sephin 1 | Sephin 1 is a selective PPP1R15A inhibitor devoid of PPP1R15B and α2-adrenergic activity. In cells, Sephin 1 selectively disrupted the PPP1R15A-PP1c complex, thus prolonging eIF2α phosphorylation after stress, delaying translation recovery, and attenuated expression of stress genes such as the pro-apoptotic protein CHOP. In mice, Sephin 1 safely prevented the motor, morphological, and molecular defects of two otherwise unrelated protein-misfolding diseases. Uses: Potential treatment of protein misfolding disease. Group: Pharmaceutical. Alternative Names: Sephin1; Sephin-1. CAS No. 951441-04-6. Pack Sizes: 250 mg. Product ID: B1370-055259. Molecular formula: C8H9ClN4. Mole weight: 196.64. Custom synthesis is available. Send your inquiries for more information. | London |
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