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| Product | Description | |
|---|---|---|
| Pomalidomide | Pomalidomide promotes degradation of transcription factors SALL4, IKZF1 and IKZF3. Group: Pharmaceutical. Alternative Names: CC4047; CC 4047; CC-4047. CAS No. 19171-19-8. Pack Sizes: 2.5 g. Product ID: B0084-086591. Molecular formula: C13H11N3O4. Mole weight: 273.24. Custom synthesis is available. Send your inquiries for more information. |  London |
| Pomalidomide-C2-NH2 | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Group: Pharmaceutical. Alternative Names: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. CAS No. 1957235-66-3. Pack Sizes: 25 mg. Product ID: BAT-006493. Molecular formula: C15H16N4O4. Mole weight: 316.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Pomalidomide-PEG1-azide | Pomalidomide-PEG1-azide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal azide for click chemistry with a target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Group: Pharmaceutical. Alternative Names: Pomalidomide-NH-PEG1-N3; 2-(2-Azidoethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide. CAS No. 2133360-04-8. Pack Sizes: 50 mg. Product ID: B1370-285241. Molecular formula: C17H16N6O6. Mole weight: 400.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Pomalidomide-PEG3-C2-NH2 hydrochloride | Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 3 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. Alternative Names: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Pack Sizes: 100 mg. Product ID: B2693-052918. Molecular formula: C21H29ClN4O7. Mole weight: 484.93. Custom synthesis is available. Send your inquiries for more information. | London |
| Pomalidomide-PEG5-CO2H | Pomalidomide-PEG5-CO2H is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal carboxylic acid for reactivity with an amine on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Group: Pharmaceutical. Alternative Names: 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid. CAS No. 2139348-63-1. Pack Sizes: 25 mg. Product ID: B2693-285227. Molecular formula: C26H35N3O11. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| CC-17368 | CC-17368 is a hydroxyisoindole derivative and metabolite of pomalidomide that has potential activity in anticancer study like multiple myeloma. Group: Pharmaceutical. Alternative Names: CC 17368; CC17368; Pomalidomide metabolite M17; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-. CAS No. 1547162-41-3. Pack Sizes: 100 mg. Product ID: B2694-475859. Molecular formula: C13H11N3O5. Mole weight: 289.25. Custom synthesis is available. Send your inquiries for more information. | London |
| TL13-112 | TL13-112 is a potent and selective PROTAC® degrader targeting anaplastic lymphoma kinase (ALK) with an IC50 value of 0.14 nM, consisiting of a cereblon E3 ligase ligand Pomalidomide conjugated to an ALK inhibitor by a linker. Group: Pharmaceutical. Alternative Names: TL 13-112; TL-13-112; N-[2-[2-[2-[4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetamide; N-(2-{2-[2-(4-{4-[(5-Chloro-4-{[2-(isopropylsulfonyl)phenyl]amino}-2-pyrimidinyl)amino]-5-isopropoxy-2-methylphenyl}-1-piperidinyl)ethoxy]ethoxy}ethyl)-N2-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide; Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-1-piperidinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-. CAS No. 2229037-19-6. Pack Sizes: 5 mg. Product ID: B1370-292444. Molecular formula: C49H60ClN9O10S. Mole weight: 1002.57. Custom synthesis is available. Send your inquiries for more information. | London |
| TL13-12 | TL13-12 is a potent PROTAC® degrader targeting anaplastic lymphoma kinase (ALK) with an IC50 value of 0.69 nM, consisiting of a cereblon E3 ligase ligand Pomalidomide conjugated to an ALK inhibitor by a linker. Group: Pharmaceutical. Alternative Names: TL 13-12; TL-13-12; Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-3-methoxyphenyl]-1-piperazinyl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-; N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide. CAS No. 2229037-04-9. Pack Sizes: 5 mg. Product ID: B1370-292442. Molecular formula: C45H53ClN10O10S. Mole weight: 961.48. Custom synthesis is available. Send your inquiries for more information. | London |
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