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Pneumocandin A0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Pneumocandin A0 is an impurity of Micafungin. Group: Pharmaceutical. Alternative Names: 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine, cyclic peptide deriv.; Antibiotic L 671329; L 671329; Stereoisomer of N2-(10,12-dimethyl-1-oxotetradecyl)-4,5-dihydroxy-L-ornithyl-L-threonyl-4-hydroxy-L-prolyl-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-proline cyclic (6→1)-peptide. CAS No. 120692-19-5. Pack Sizes: 10 mg. Product ID: BBF-02575. Molecular formula: C51H82N8O17. Mole weight: 1079.24. Custom synthesis is available. Send your inquiries for more information.
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FR 179642
FR 179642 is an impurity of Micafungin, which is an antifungal agent. Group: Pharmaceutical. Alternative Names: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. CAS No. 168110-44-9. Pack Sizes: 20 mg. Product ID: BAT-010112. Molecular formula: C35H52N8O20S. Mole weight: 936.89. Custom synthesis is available. Send your inquiries for more information.
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FR 901379
FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection. Group: Pharmaceutical. Alternative Names: 1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; (2α,3β,4β)-(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-Proline Cyclic (6→1)-Peptide; 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine Cyclic Peptide Deriv. CAS No. 144371-88-0. Pack Sizes: 1mg;1g;10g. Product ID: BAT-010111. Molecular formula: C51H82N8O21S. Mole weight: 1175.3. Custom synthesis is available. Send your inquiries for more information.
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Micafungin
Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. In a mouse model of septic A. fumigatus infection, although non-treated mice survived for a maximum of only 6 days, the survival rate of micafungin-treated mice (0.1 mg kg-1) increased to 20%, while the survival rate of mice treated with a combination of micafungin (0.1 mg kg-1) and KB425796-C (32 mg kg-1) increased to 100% during the 31-day post-infection period. Uses: Antifungal agents. Group: Pharmaceutical. Alternative Names: 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; Mycamine; FK463. CAS No. 235114-32-6. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03857. Molecular formula: C56H71N9O23S. Mole weight: 1270.27. Custom synthesis is available. Send your inquiries for more information.
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O-Desulfo Micafungin
O-Desulfo Micafungin is an impurity of caspofungin or micafungin. Micafungin is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. Group: Pharmaceutical. Alternative Names: Micafungin (m1); Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)-; 1-((4R,5R)-4,5-Dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)pneumocandin A0. CAS No. 539823-80-8. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05832. Molecular formula: C56H71N9O20. Mole weight: 1190.23. Custom synthesis is available. Send your inquiries for more information.
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