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| Product | Description | |
|---|---|---|
| β-Nicotinamide Adenine Dinucleotide | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of several enzymes, such as poly(ADP)-ribose polymerases and cADP-ribose synthases. NAD+ is commonly used as an oxidizing agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 53-84-9. Pack Sizes: 10 g. Product ID: B0084-094034. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| D-Glucose-6-phosphate dipotassium salt trihydrate | D-Glucose-6-phosphate dipotassium salt trihydrate is a pivotal compound extensively employed in the biomedical research and pharmaceutical industry, unveiling noteworthy potential in investigating intricate metabolic disorders and glucose metabolism. This paramount product seamlessly acts as a substrate for a diverse array of enzymes, facilitating the meticulous identification and characterization of pertinent pathways germane to therapeutic drug development of afflictions such as diabetes and glycogen storage diseases. Group: Pharmaceutical. CAS No. 207727-36-4. Pack Sizes: 250 mg. Product ID: B2705-101654. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Acetyl-α-D-glucosamine-1-phosphate disodium salt | N-Acetyl-α-D-glucosamine-1-phosphate disodium salt is an indispensable compound in the biomedical sector with applications extending to studying an array of diseases and conditions, including particular enzyme deficiencies and genetic disorders. Group: Pharmaceutical. CAS No. 31281-59-1. Pack Sizes: 25 mg. Product ID: B1370-369865. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PseudoUridine 5'-monophosphate Sodium salt | A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: B1370-285301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Vicine | Vicine is an alkaloid glycoside found mainly in fava beans. It is related to the loss of the enzyme glucose-6-phosphate dehydrogenase. Uses: Anti-arrhythmic. Group: Pharmaceutical. CAS No. 152-93-2. Pack Sizes: 20 mg. Product ID: B2703-464844. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| D-Fructose 1-phosphate disodium salt | D-Fructose 1-phosphate disodium salt is a crucial component used in the biomedical industry playing a vital role in the research of metabolic disorders and genetic diseases associated with defects in fructose metabolism. This product acts as a substrate for the enzymatic reaction leading to the conversion of fructose-1-phosphate to fructose-6-phosphate, facilitating normal fructose metabolism. Group: Pharmaceutical. CAS No. 71662-09-4. Pack Sizes: 5 mg. Product ID: B1370-149824. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DL-α-Glycerophosphate | DL-α-Glycerophosphate is a renowned chemical compound with a remarkable attribute of DL-α-Glycerophosphate liying in its pivotal role as a substrate in enzymatic determinations of alkaline phosphatase activity. Unveiling its vast potential, DL-α-Glycerophosphate holds promise in the research of critical ailments, such as osteoporosand other grave bone-related disorders. Group: Pharmaceutical. CAS No. 57-03-4. Pack Sizes: 100 g. Product ID: B1370-027988. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 87860-39-7. Pack Sizes: 1 mg. Product ID: B1370-381555. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KY-226 | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. It significantly reduced plasma glucose, triglyceride, and A1c levels without weight gain in db/db mice. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 1621673-53-7. Pack Sizes: 25 mg. Product ID: B2693-010435. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tricirbine | Triciribine is a potent AKT inhibitor and a cell-permeable tricyclic nucleoside molecule with potential antineoplastic activity. Akt-1, -2, and -3 are serine/threonine protein kinases in the phosphatidylinositol (PI3)-kinase signalling pathway that play a critical role in the regulation of cell proliferation and survival. Following recruitment of Akt to the plasma membrane, phosphorylation at threonine 308 and serine 473 (Akt-1 numbering) by phosphoinositide-dependent kinases (PDK) 1 and 2 results in full activation of the enzyme. Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit phosphatidylinositol 3 (PI3)-Kinase or PDK1, the direct upstream activators of Akt, nor does it inhibit PKC, PKA, ERK1/2, serum- and glucocorticoid-inducible kinase, p38, STAT3, or JNK signalling pathways. Triciribine effectively inhibits growth of Akt-overexpressing human cancer cell lines in vitro with 50% inhibition at ~5-10 μM. It also inhibit growth of tumor xenografts in mice by greater than 80% at a dose of 1 mg/kg/day. Group: Pharmaceutical. CAS No. 35943-35-2. Pack Sizes: 100 mg. Product ID: B1370-090988. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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