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| Product | Description | |
|---|---|---|
| 2'-Deoxycytidine 3'-monophosphate ammonium salt | 2'-Deoxycytidine 3'-monophosphate ammonium salt is a nucleotide-like compound that is extensively employed in scientific research, especially in the disciplines of DNA sequencing and synthesis. Furthermore, it serves as an essential ingredient for various phosphatases and kinases. With its unique properties, it has the potential to combat a variety of viral infections and cancers, thus opening up new avenues for therapeutic interventions. Group: Pharmaceutical. CAS No. 102783-50-6. Pack Sizes: 20 mg. Product ID: B2001-297040. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 3-O-Methylfluorescein phosphate cyclohexylammonium salt | A fluorogenic substrate for phosphatase. Group: Pharmaceutical. CAS No. 21233-09-0. Pack Sizes: 1 g. Product ID: B2699-070640. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A | 6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Group: Pharmaceutical. CAS No. 121584-52-9. Pack Sizes: 10 mg. Product ID: B2705-116989. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Abyssinone V | Abyssinone V is extracted from the root bark of Erythrina mildbraedii. It is a protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 values ranging from 14.8 to 39.7 microM. Group: Pharmaceutical. CAS No. 77263-11-7. Pack Sizes: 1mg; 1g; 10g. Product ID: NP2310. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| APS-5 | APS-5 is a chemiluminescent substrate based on 9, 10-dihydroacridine, which is mainly used for ELISA detection of alkaline phosphatase AP conjugated compounds and for the diagnosis of immune detection, such as tumor markers, infectious diseases, endocrine function, hormones, etc. Group: Pharmaceutical. CAS No. 193884-53-6. Pack Sizes: 100 mg. Product ID: B2708-285642. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AS 1842856 | AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Group: Pharmaceutical. CAS No. 836620-48-5. Pack Sizes: 200 mg. Product ID: B1370-054875. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| C16 Ceramide | C16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3. Uses: A predominant, rather hydrophobic natural ceramide. activates a cytosolic serine/threonine protein phosphatase in t9 cells; induces egf receptor phosphorylation in a-431 cells; stimulates ceramide-activated protein kinase. Group: Pharmaceutical. CAS No. 24696-26-2. Pack Sizes: 100 mg. Product ID: B1370-059982. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CSPD | CSPD is a chemiluminescent alkaline phosphatase substrate used for the imprinting of proteins or nucleic acids on nitrocellulose membranes. Group: Pharmaceutical. CAS No. 142456-88-0. Pack Sizes: 10 mg. Product ID: B2708-051725. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cyclosporin Impurity 4 | Cyclosporin Impurity 4 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Group: Pharmaceutical. CAS No. 59865-23-5. Pack Sizes: 5 mg. Product ID: BBF-05747. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deoxypyridinoline | Deoxypyridinoline is one of two pyridinium cross-links that provide structural stiffness to type I collagen found in bones. It can be used along with other bone markers such as alkaline phosphatase, osteocalcin, and N-terminal telopeptide to diagnose bone diseases such as postmenopausal osteoporosis, bone metastasis, and Paget's disease. Group: Pharmaceutical. CAS No. 83462-55-9. Pack Sizes: 1 mg. Product ID: B2694-136861. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DL-α-Glycerophosphate | DL-α-Glycerophosphate is a renowned chemical compound with a remarkable attribute of DL-α-Glycerophosphate liying in its pivotal role as a substrate in enzymatic determinations of alkaline phosphatase activity. Unveiling its vast potential, DL-α-Glycerophosphate holds promise in the research of critical ailments, such as osteoporosand other grave bone-related disorders. Group: Pharmaceutical. CAS No. 57-03-4. Pack Sizes: 100 g. Product ID: B1370-027988. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fortunellin | Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation. Group: Pharmaceutical. CAS No. 20633-93-6. Pack Sizes: 5 mg. Product ID: NP4561. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 87860-39-7. Pack Sizes: 1 mg. Product ID: B1370-381555. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KY-226 | KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that protects neurons from cerebral ischemic injury. It significantly reduced plasma glucose, triglyceride, and A1c levels without weight gain in db/db mice. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 1621673-53-7. Pack Sizes: 25 mg. Product ID: B2693-010435. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| LB-100 | LB-100 is a water-soluble protein phosphatase 2A (PP2A) inhibitor (IC50 = 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells) that enhanced the effects of sorafenib in HCC cells only during hypoxic environments. Group: Pharmaceutical. CAS No. 1632032-53-1. Pack Sizes: 100 mg. Product ID: B1370-474642. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| O-Sulfonato-L-tyrosine sodium salt | O-Sulfonato-L-tyrosine sodium salt, an amino acid derivative utilized in biomedical research, presents itself as a valuable asset. Its application as a protein tyrosine phosphatase and kinase specificity substrate highlights its pertinence in the industry. Excitingly, it has been researched extensively for its anti-inflammatory attributes and could potentially offer new remedies for autoimmune diseases. Group: Pharmaceutical. CAS No. 98930-06-4. Pack Sizes: 100 mg. Product ID: BAT-006967. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TNO155 | TNO155 is an inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11), with potential antineoplastic activity. Group: Pharmaceutical. CAS No. 1801765-04-7. Pack Sizes: 5 mg. Product ID: B2693-008828. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ursodeoxycholic Acid | Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases. Ursodeoxycholic acid may be used to study its specific activities that range from reduction of cholesterol absorpition, cholesterol gallstone dissolution to suppression of immune response.IC50: M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); NTCP: IC50=3.6 μM (human); HCT-116: IC50=>50 μM (human); GBM: IC50=>50 μM (human) Asbt: Ki=75 μM (human). Uses: Gallstone-dissolving drugs; anti-neoplastic; for the prevention and treatment of cholesterol gallstones; reduces hydrophobic bile acids and decreases both lymphocyte reactivity and serum alkaline phosphatase levels,ic50: m1-family aminopeptidase: ic50=2.6 μm (plasmodium falciparum 3d7); ntcp: ic50=3.6 μm (human); hct-116: ic50=>50 μm (human); gbm: ic50=>50 μm (human) asbt: ki= 75 μm (human). Group: Pharmaceutical. CAS No. 128-13-2. Pack Sizes: 100 g. Product ID: NP6089. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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