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| Product | Description | |
|---|---|---|
| Phenyl phosphate disodium salt dihydrate | 100g Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C6H5Na2O4P · 2H2O. CAS No. 3279-54-7. Prepack ID : 25199073-100g. Molecular Weight : 254.09. |  |
| Phenyl phosphate disodium salt dihydrate | 25g Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C6H5Na2O4P · 2H2O. CAS No. 3279-54-7. Prepack ID : 25199073-25g. Molecular Weight : 254.09. | |
| di-tert-butylphenyl phenyl phosphate | Di-tert-butylphenyl phenyl phosphate, a phosphorus-containing flame retardant, is frequently utilized in the manufacturing of plastics, textiles, and electronic devices. Additionally, it serves as a polyvinyl chloride stabilizer and as a thermal stabilizer in lubricating oils. However, some studies have revealed that it has the potential to cause endocrine disruption and neurotoxicity, which has prompted certain countries to restrict its usage. Group: Pharmaceutical. Alternative Names: Bis(tert-butylphenyl)phenyl Phosphate; Phosphoric acid, bis[(1,1-dimethylethyl)phenyl] phenyl ester; Bis(o-tert-butylphenyl) phenyl phosphate; Di-(t-butylphenyl) phenyl phosphate; bis(t-butylphenyl) phenyl phosphate. CAS No. 65652-41-7. Pack Sizes: 100 mg. Product ID: B0001-276863. Molecular formula: C26H31O4P. Mole weight: 438.5. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2-O-DMT-sulfonyldiethanol phosphoramidite | 2-O-DMT-sulfonyldiethanol phosphoramidite substantiates its inevitable prowess in the synthesis and alteration of nucleic acids across diverse applications. Unparalleled in its chemical composition, this exceptional concoction facilitates meticulous and efficient manipulation of nucleic acids, thus fostering elevated biomedical exploration with incomparable precision. Group: Pharmaceutical. Alternative Names: 2-((2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)sulfonyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl]sulfonyl]ethyl 2-cyanoethyl ester; 2-[2-(4,4'-dimethoxytrityloxy)ethylsulfonyl]ethyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 2-O-DMT-S phosphoramidite; 5'-Phosphate-Amidite; O-DMT-2,2'-sulfonyldiethanol phosphoramidite; 5'-Phosphate-ON Reagent. CAS No. 108783-02-4. Pack Sizes: 10 g. Product ID: B1370-341811. Molecular formula: C34H45N2O7PS. Mole weight: 656.77. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Phenoxy-4H-1,3,2-benzodioxaphosphorin 2-oxide | 2-Phenoxy-4H-1,3,2-benzodioxaphosphorin 2-oxide, a phosphorus-loaded molecule, possesses antiviral and antitumor properties. Its efficacy against cancer cells and replication of viruses has been convincingly established. Its potential uses in treating autoimmune diseases are also being examined. Group: Pharmaceutical. Alternative Names: Phenylsalioxon; Phenyl saligenin phosphate; Phenylsaligenin cyclic phosphate; Salioxon-phenyl. CAS No. 4081-23-6. Pack Sizes: 100 mg. Product ID: B2699-231828. Molecular formula: C13H11O4P. Mole weight: 262.2. Custom synthesis is available. Send your inquiries for more information. | London |
| ABBV-167 | ABBV-167 is a phosphate prodrug of venetoclax, a Bcl-2 inhibitor. Group: Pharmaceutical. Alternative Names: Benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-((7-((phosphonooxy)methyl)-7H-pyrrolo(2,3-b)pyridin-5-yl)oxy)-; (5-{5-(4-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-2-[({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)carbamoyl]phenoxy}-7H-pyrrolo[2,3-b]pyridin-7-yl)methyl dihydrogen phosphate. CAS No. 1351456-78-4. Pack Sizes: 1mg;1g;10g. Product ID: 1351456-78-4. Molecular formula: C46H53ClN7O11PS. Mole weight: 978.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Angiotensin A | Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. It causes pressor and renal vasoconstrictor effects in rodents by the AT1 receptor. It is inhibited by Candesartan but not by AT2 receptor ligands in vivo. It also increases inositol phosphate accumulation with a similar potency to Ang II with EC50 value of 6.7 nM. Group: Pharmaceutical. Alternative Names: Ala-Angiotensin III; H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Ang A; Angiotensin II, 1-L-alanine-5-L-isoleucine-; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine. CAS No. 51833-76-2. Pack Sizes: 10 mg. Product ID: BAT-015367. Molecular formula: C49H71N13O10. Mole weight: 1002.18. Custom synthesis is available. Send your inquiries for more information. | London |
| CSPD | CSPD is a chemiluminescent alkaline phosphatase substrate used for the imprinting of proteins or nucleic acids on nitrocellulose membranes. Group: Pharmaceutical. Alternative Names: 3-(2'-(Spiro-5-chloroadamantane))-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane; 3-(4-Methoxyspiro(1,2-dioxetane-3,2'-(5'-chloro)tricyclo(3.3.1.1(3,7))decan)-4-yl)phenyl phosphate; Phenol, 3-(5'-chloro-4-methoxyspiro(1,2-dioxetane-3,2'-tricyclo(3.3.1.1(3,7))decan)-4-yl)-, dihydrogen phosphate. CAS No. 142456-88-0. Pack Sizes: 10 mg. Product ID: B2708-051725. Molecular formula: C18H22ClO7P. Mole weight: 416.79. Custom synthesis is available. Send your inquiries for more information. | London |
| OXi-4503 | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. In addition, orthoquinone intermediates, metabolized from combretastatin A1 by oxidative enzymes found to be elevated levels in some tumor types, may bind to tumor cell thiol-specific antioxidant proteins and DNA, and stimulate oxidative stress by enhancing superoxide/hydrogen peroxide production. CA1 binds to tubulin at the same site as colchicine but with higher affinity. Group: Pharmaceutical. Alternative Names: OXi4503; OXi 4503; CA1P; tetrasodium [3-methoxy-2-phosphonatooxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate. CAS No. 288847-35-8. Pack Sizes: 100 mg. Product ID: B0084-353235. Molecular formula: C18H22O12P2. Mole weight: 492.31. Custom synthesis is available. Send your inquiries for more information. | London |
| OXi-4503 sodium | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. The U.S. Food and Drug Administration (FDA) has granted fast-track designation to OXi-4503, a vascular disrupting agent shown to cause tumor cell death and necrosis, for the treatment of relapsed/refractory acute myeloid leukemia (AML). Group: Pharmaceutical. Alternative Names: sodium (Z)-3-methoxy-6-(3,4,5-trimethoxystyryl)-1,2-phenylene bis(phosphate); OXi4503; OXi-4503; OXi 4503; OXi-4503 sodium, CA1P; Combretastatin A-1 phosphate. CAS No. 288847-34-7. Pack Sizes: 1mg;1g;10g. Product ID: 288847-34-7. Molecular formula: C18H22Na4O12P2. Mole weight: 584.23. Custom synthesis is available. Send your inquiries for more information. | London |
| PSI-7976 | PSI-7976 is an inhibitor of HCV RNA replication with EC50 value of 1.07μM. PSI-7851 is a phosphoramidate prodrug of PSI-7411 and has potent anti-hepatitis C virus (HCV) activity. It is a mixture of two diastereoisomers. PSI-7976 is one of them. Another one is PSI-7977. PSI-7851 is firstly activated through being hydrolyzed by CatA and CES1in the liver cells. It is found that CatA prefers PSI-7977 as a substrate over PSI-7976 while CES1 preferentially hydrolyzes PSI-7976 over PSI-7977. Since CES1 does not express in clone A replicon cells, the ability of PSI-7976 and PSI-7977 to inhibit HCV RNA replication is different in these cells. PSI-7977 is more potent than PSI-7976 with EC50 value of 92nM. Group: Pharmaceutical. Alternative Names: Sofosbuvir (R)-Phosphate; (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. CAS No. 1190308-01-0. Pack Sizes: 25 mg. Product ID: B2693-463118. Molecular formula: C22H29FN3O9P. Mole weight: 529.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Solid Chemical phosphorylation reagent II | Solid Chemical phosphorylation reagent II is a click chemistry reagent for the synthesis of oligonucleotides possessing 5'-terminal phosphate residues. Group: Pharmaceutical. Alternative Names: Chemical phosphorylation amidite; [3-(4,4'-Dimethoxytrityloxy)-2,2-dicarboxymethylamido]propyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-(methylamino)-2-[(methylamino)carbonyl]-3-oxopropyl 2-cyanoethyl ester; Solid Chemical Phosphorylation Reagent 2; 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(methylamino)-2-(methylcarbamoyl)-3-oxopropyl(2-cyanoethyl)(N,N-diisopropyl)phosphoramidite. CAS No. 202284-84-2. Pack Sizes: 250 mg. Product ID: BADC-01951. Molecular formula: C37H49N4O7P. Mole weight: 692.79. Custom synthesis is available. Send your inquiries for more information. | London |
| Tenapanor HCl | Tenapanor, also known as AZD-1722 and RDX 5791, is a first-in-class, small-molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger NHE3. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor acts in the gastrointestinal tract to reduce the absorption of sodium and phosphate, with minimal systemic drug exposure. Group: Pharmaceutical. Alternative Names: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide dihydrochloride; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor; Tenapanor hydrochloride; Tenapanor dihydrochloride. CAS No. 1234365-97-9. Pack Sizes: 50 mg. Product ID: B2693-007851. Molecular formula: C50H68Cl6N8O10S2. Mole weight: 1217.9. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-FAM-DMT-phosphoramidite | 6-FAM-DMT Phosphoramidite is a phosphoramidite derivative used to introduce 6-carboxyfluorescein (6-FAM) into oligonucleotides during solid-phase synthesis. It includes a 6-FAM fluorophore and a dimethoxytrityl (DMT) protecting group, which facilitates efficient incorporation and subsequent deprotection during synthesis. This reagent enables the production of fluorescently labeled oligonucleotides for applications such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays. Group: Pharmaceutical. Alternative Names: 6-Fluorescein Phosphoramidite; 2-Dimethoxytrityloxymethyl-6-(3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-6-Fluorescein phosphoramidite (with DMT); Propanoic acid, 2,2-dimethyl-, 6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; DMT-6-FAM phosphoramidite. CAS No. 316121-60-5. Pack Sizes: 250 mg. Product ID: B1370-070723. Molecular formula: C68H78N3O13P. Mole weight: 1176.33. Custom synthesis is available. Send your inquiries for more information. | London |
| IPI-549 | IPI-549, a dihydroisoquinolin derivative, has been found to be a phosphatidylinositol 3 kinase gamma inhibitor, could exhibit antineoplastic activity in solid tumors. It is still under Phase I trial. IC50: 16 nM (PI3Kγ), 3.2 μM (PI3Kα), 3.5 μM (PI3Kβ), >8.4 μM (PI3Kδ). Group: Pharmaceutical. Alternative Names: Eganelisib; IPI 549; IPI549; 2-Amino-N-[(1S)-1-[1,2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; (S)-2-Amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. CAS No. 1693758-51-8. Pack Sizes: 50 mg. Product ID: B0084-475947. Molecular formula: C30H24N8O2. Mole weight: 528.58. Custom synthesis is available. Send your inquiries for more information. | London |
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