Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| Deep Blue Pro PH Minus 10Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Subject to available stock, heavy orders may be sent as multiples of smaller tubs. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Pack Size: 10 litre. Product ID: 0666186536308. MPN: DBPPHMINUS-10. Brand: Deep Blue Pro. Categories: Pool Chemicals. |  Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 14Kg (2x7Kg) PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 Gallons) of water - add 450g Medium pool 60,000 litres (13200 Gallons) of water - a . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 5060220090576. MPN: DBPPHMINUS-7Box. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 1.5Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 Gallons) of water - add 450g Medium pool 60,000 litres (13200 Gallons) of water - a . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 0666186537008. MPN: DBPPHMINUS-1.5S. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 1Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 Gallons) of water - add 450g Medium pool 60,000 litres (13200 Gallons) of water - a . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Pack Size: 1 litre. Product ID: 0666186535721. MPN: DBPPHMINUS-1. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 20Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Subject to available stock, heavy orders may be sent as multiples of smaller tubs. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Pack Size: 20 litre. Product ID: 5060220074057. MPN: DBPPHMINUS-20. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 25Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Subject to available stock, heavy orders may be sent as multiples of smaller tubs. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Pack Size: 25 litre. Product ID: 5060220073852. MPN: DBPPHMINUS-25. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 2Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 Gallons) of water - add 450g Medium pool 60,000 litres (13200 Gallons) of water - a . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Pack Size: 2 litre. Product ID: 0666186536315. MPN: DBPPHMINUS-2. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 5Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Subject to available stock, heavy orders may be sent as multiples of smaller tubs. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Pack Size: 5 litre. Product ID: 0666186536322. MPN: DBPPHMINUS-5. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 7Kg PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 Gallons) of water - add 450g Medium pool 60,000 litres (13200 Gallons) of water - a . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 0666186537015. MPN: DBPPHMINUS-7S. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro PH Minus 9KG (6x 1.5Kg) PH- pH decreaser | PH minus granules enables you to decrease the pH of your pool or hot tub to the ideal level, which is between 7.2 - 7.6, promoting bather comfort, optimum chemical efficiency and protection of pool plant equipment. Test the pH of your pool water if it is above 7.6, use pH minus to lower it. Application Instructions: 1. Pre-dissolve the product in a clean plastic container at a maximum rate of 100g of product per 10 Litres of clean warm water. Stir well to ensure product is fully dissolved. Carefully add the resulting solution to the water whilst the pump(s) are turned 'on', preferably near to the water inlets to aid distribution. 2. After a minimum of 8 hours, recheck the pH level and if necessary repeat the treatment until the ideal pH is established. Please note a number of treatments may be required. Dosing rates: Hot tub: 1,000 litres (220 Gallons) of water add 10g Small pool 40,000 litres (8800 Gallons) of water - add 450g Medium pool 60,000 litres (13200 Gallons) of water - a . Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 5060220090569. MPN: DBPPHMINUS-1.5Box. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| 1,1-Dimethylbiguanide hydrochloride | 1,1-Dimethylbiguanide hydrochloride is the hydrochloride salt of the biguanide metformin with antihyperglycemic and potential antineoplastic activities. It decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Uses: Hypoglycemic agents. Group: Pharmaceutical. Alternative Names: Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1); Biguanide, 1,1-dimethyl-, hydrochloride; Biguanide, 1,1-dimethyl-, monohydrochloride; Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride; Apo-Metformin; Apophage; Benofomin; Brot; Dabex; Denkaform; Fornidd; Geamet; Glifage; LA 6023; Meguan; Metformin hydrochloride; N,N-Dimethylbiguanide hydrochloride; N1,N1-Dimethylbiguanide hydrochloride; Nelbis; Neodipa; Obimat-SR; Orabet; Riomet; Siamformet; Walaphage. CAS No. 1115-70-4. Pack Sizes: 500 g. Product ID: BBF-04609. Molecular formula: C4H12ClN5. Mole weight: 165.62. Custom synthesis is available. Send your inquiries for more information. |  London |
| 1,4-di-tert-butyl-2,5-bis(2,2,2-trifluoro-ethoxy)benzene | 1,4-Di-tert-butyl-2,5-bis(2,2,2-trifluoro-ethoxy)benzene, a fluorinated aromatic entity, has been studied extensively for its promising potential to augment the efficiency of organic solar cells. As an additive, it imparts exceptional electron mobility while concurrently decreasing the recombination of charge carriers. On another note, it displays self-assembly capabilities into nanostructures, making it a hopeful candidate in the realm of drug delivery systems. Group: Pharmaceutical. Alternative Names: 1,4-bis(2,2,2-trifluoroethoxy)-2,5-di-tert-butylbenzene; Benzene, 1,4-bis(1,1-dimethylethyl)-2,5-bis(2,2,2-trifluoroethoxy)-; 1,4-Bis(2-methyl-2-propanyl)-2,5-bis(2,2,2-trifluoroethoxy)benzene. CAS No. 1147737-68-5. Pack Sizes: 100 mg. Product ID: B0001-428038. Molecular formula: C18H24F6O2. Mole weight: 386.37. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-b-C-Ethynyladenosine | 2'-b-C-Ethynyladenosine is a potent antiviral agent used to treat viral infections such as hepatitis B and C. This product works by inhibiting viral RNA synthesis and preventing viral replication in host cells, ultimately resulting in a decrease in viral load. It has also shown potential in treating certain types of cancers and autoimmune disorders due to its ability to target rapidly dividing cells. Group: Pharmaceutical. Alternative Names: (2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-3-ethynyl-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2'-beta-C-Ethynyladenosine; Adenosine, 2'-C-ethynyl-; 2'-β-C-Ethynyladenosine. CAS No. 640725-76-4. Pack Sizes: 25 mg. Product ID: B1370-051947. Molecular formula: C12H13N5O4. Mole weight: 291.26. Custom synthesis is available. Send your inquiries for more information. | London |
| (2-Carboxyphenyl)phenyliodonium Hydroxide Inner Salt | (2-Carboxyphenyl)phenyliodonium Hydroxide Inner Salt, a frequently utilized substance in biomedical disciplines, exhibits significant potential in suppressing cancerous and microbial growth. It impedes the proliferative activities of malignancies and bacteria resulting in a substantial decrease in the rate of progression and transmission of diseases. It has been extensively studied, and it has been proven to have minimal morbidity, making it an excellent candidate for future advancements in medicinal research. Group: Pharmaceutical. Alternative Names: Diphenyliodonium-2-carboxylate; 2-(phenyliodonio)benzoate; Iodonium, (2-carboxyphenyl)phenyl-, inner salt; (2-Carboxylatophenyl)phenyliodonium. CAS No. 1488-42-2. Pack Sizes: 10 g. Product ID: B2699-290503. Molecular formula: C13H9IO2·H2O. Mole weight: 324.11. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Methyltoxoflavin | 3-Methyltoxoflavin is a novel Hsp90 inhibitor, which decreases the Hsp90-dependent client protein HER2 and induces cell death. Group: Pharmaceutical. Alternative Names: 3-Methyltoxoflavin; 3 Methyltoxoflavin; 3Methyltoxoflavin; GNF-Pf-2272; 1,3,6-Trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione. CAS No. 32502-62-8. Pack Sizes: 10 mg. Product ID: B0084-284785. Molecular formula: C8H9N5O2. Mole weight: 207.193. Custom synthesis is available. Send your inquiries for more information. | London |
| 4,4'-Diaminodiphenylsulfone | Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase. Uses: Anti-inflammatory agent. Group: Pharmaceutical. Alternative Names: 4-(4-aminophenyl)sulfonylaniline. CAS No. 80-08-0. Pack Sizes: 1 kg. Product ID: NP2822. Molecular formula: C12H12N2O2S. Mole weight: 248.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-IBP | 4-IBP, an agonist that specially targets sigma receptor (IC50= 1.7 nM), induced marked concentration-dependent decreases in the growth of human cancer cells. Group: Pharmaceutical. Alternative Names: 4 IBP;4IBP; N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide; N-(1-Benzyl-4-piperidinyl)-4-iodobenzamide. CAS No. 155798-08-6. Pack Sizes: 100 mg. Product ID: B1370-191516. Molecular formula: C19H21IN2O. Mole weight: 420.29. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Octyl itaconate | 4-Octyl itaconate is a prodrug form of itaconate, an endogenous cellular metabolite produced via decarboxylation of cis-aconitate by the enzyme encoded by IRG1. It activates Nrf2. It inhibits LPS-induced increases in IL-1β mRNA, HIF-1α and IL-10 in macrophages. It decreases cytokine production in response to LPS in mice and prolongs survival. Group: Pharmaceutical. Alternative Names: Itaconic acid 4-octyl ester; 2-Methylidene-4-octoxy-4-oxobutanoic acid. CAS No. 3133-16-2. Pack Sizes: 100 mg. Product ID: B0001-007866. Molecular formula: C13H22O4. Mole weight: 242.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride | 5-(2-Chlorobenzyl)thieno(3,2-C)pyridinium chloride is an impurity of Ticlopidine, a reversible P2Y12 receptor antagonist used to decrease the risk of stroke in patients known to have atherosclerosis. Group: Pharmaceutical. Alternative Names: 5-(2-Chlorobenzyl)-thieno[3,2-c]pyridinium Chloride; 5-[(2-Chlorophenyl)methyl]-thieno[3,2-c]pyridinium Chloride. CAS No. 53885-64-6. Pack Sizes: 25 mg. Product ID: B1370-469260. Molecular formula: C14H11Cl2NS. Mole weight: 296.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Bromo-cAMP sodium salt | 8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis. Group: Pharmaceutical. Alternative Names: 8-Br-3',5'-cyclo-adenosine monophosphate, sodium salt; 8-Br-3',5'-cyclo-AMP.Na; (8Br-cAMP) sodium salt; 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt; 8-Br-cAMP sodium salt; 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1). CAS No. 76939-46-3. Pack Sizes: 100 mg. Product ID: B1370-005325. Molecular formula: C10H10BrN5NaO6P. Mole weight: 430.08. Custom synthesis is available. Send your inquiries for more information. | London |
| A 1070722 | A 1070722 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 0.6 nM for GSK-3α and GSK-3β) with 50-fold selectivity over other protein kinases such as CDK. It decreases phosphorylation of microtubule-associated protein Tau in vitro. A 1070722 exhibits neuroprotective activity thus is identified as a therapeutic drug candidate for neurodegenerative and psychiatric disorders. Uses: Potential treatment of neurodegenerative disorders. Group: Pharmaceutical. Alternative Names: A 1070722; A1070722; A-1070722; 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea. CAS No. 1384424-80-9. Pack Sizes: 1mg;1g;10g. Product ID: 1384424-80-9. Molecular formula: C17H13F3N4O2. Mole weight: 362.31. Custom synthesis is available. Send your inquiries for more information. | London |
| A37 | A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Group: Pharmaceutical. Alternative Names: Ethyl 2-[[3,4-dihydro-4-oxo-3-[3-(1-pyrrolidinyl)propyl][1]benzothieno[3,2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. CAS No. 896795-60-1. Pack Sizes: 1mg;1g;10g. Product ID: 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A 841720 | A 841720 is a potent non-competitive mGlu1 receptor antagonist (IC50 = 10 nM) exhibiting 34-fold selectivity over mGluR5 and inactive to other mGluR receptors, neurotransmitter receptors, ion channels, and transporters. It inhibits complete Freund's adjuvant-induced inflammatory pain (ED50 = 23 μmol/kg) and decreases mechanical allodynia (ED50 = 28 μmol/kg) in mouse models. Group: Pharmaceutical. Alternative Names: A-841720; A 841720; A841720; 3-(azepan-1-yl)-9-(dimethylamino)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one. CAS No. 869802-58-4. Pack Sizes: 1mg;1g;10g. Product ID: 869802-58-4. Molecular formula: C17H21N5OS. Mole weight: 343.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Abaloparatide | Abaloparatide is an analogue of parathyroid hormone-related protein (PTHrP) which is used for the treatment of osteoporosis. In 28 April 2017, it was approved by FDA for the treatment of postmenopausal women with osteoporosis. Studies showed that abaloparatide could decrease the risk of new vertebral and nonvertebral fractures. Uses: The treatment of osteoporosis. Group: Pharmaceutical. Alternative Names: Tymlos. CAS No. 247062-33-5. Pack Sizes: 1 mg. Product ID: BAT-006119. Molecular formula: C174H300N56O49. Mole weight: 3960.58. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-100 | ABT-100 is an orally bioavailable farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity. Group: Pharmaceutical. Alternative Names: ABT 100; ABT100; A-367074; A 367074; A367074. CAS No. 450839-40-4. Pack Sizes: 1mg;1g;10g. Product ID: 450839-40-4. Molecular formula: C27H19F3N4O3. Mole weight: 504.47. Custom synthesis is available. Send your inquiries for more information. | London |
| ABTL-0812 | ABTL-0812 is an orally bioavailable, lipid analogue and inhibitor of raptor-mammalian target of rapamycin (mTOR), rictor-mTOR and dihydrofolate reductase with potential antineoplastic activity. It binds to and inhibits both mTORC1 and mTORC2, which may result in apoptosis and a decrease in proliferation in mTORC1/2-expressing tumor cells upon oral administration. It was developed by Ability Pharmaceuticals and is in phase I/II clinical trials for the treatment of solid tumors. It received orphan drug designation in the E.U. and in the U.S. for the treatment of neuroblastoma in 2015. Uses: Abtl-0812 has potential antineoplastic activity. it is used for the treatment of solid tumors. Group: Pharmaceutical. Alternative Names: ABTL0812; ABTL 0812; ABTL-0812; (9Z,12Z)-2-hydroxyoctadeca-9,12-dienoate. CAS No. 57818-44-7. Pack Sizes: 1mg;1g;10g. Product ID: 57818-44-7. Molecular formula: C18H31O3. Mole weight: 294.93. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 186 | AC 186, also called GTPL8897, a diphenyl substituted cyclohexane derivatives, decreases Aβ levels in combination with ACP-105 in a rat model of Alzheimer's disease. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Group: Pharmaceutical. Alternative Names: 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]phenol; GTPL8897; SCHEMBL14672438; AC-186; AC 186; AC186; AKOS025147323; 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]phenol; AC 186|4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol. CAS No. 1421854-16-1. Pack Sizes: 1mg;1g;10g. Product ID: 1421854-16-1. Molecular formula: C18H17F3O. Mole weight: 306.32. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 264613 | AC 264613 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 7.5). AC 264613 inhibits interferon regulatory factor 5 and decreases interleukin-12p40 production via lipopolysaccharide-stimulated macrophages. PI hydrolysis, Ca2+ mobilization and cellular proliferation are activated by AC 264613 in vitro (pEC50 = 6.9, 7.0 and 7.5, respectively). Group: Pharmaceutical. Alternative Names: AC-264613; AC 264613; AC264613; (±)-(3R,4S)-2-Oxo-4-phenyl-3-pyrollidinecarboxylic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide. CAS No. 1051487-82-1. Pack Sizes: 1mg;1g;10g. Product ID: 1051487-82-1. Molecular formula: C19H18BrN3O2. Mole weight: 400.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Acalisib | Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immunomodulating and antineoplastic activities. p110beta/delta PI3K inhibitor GS-9820 inhibits the activity of PI3K, thereby preventing the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), which decreases tumor cell proliferation and induces cell death. PI3K-mediated signaling is often dysregulated in cancer cells; the targeted inhibition of PI3K is designed to preserve PI3K signaling in normal, non-neoplastic cells. Group: Pharmaceutical. Alternative Names: GS-9820; GS9820; GS 9820; CAL-120; CAL 120; CAL120; Acalisib; UNII-OVW60IDW1D. CAS No. 870281-34-8. Pack Sizes: 1mg;1g;10g. Product ID: 870281-34-8. Molecular formula: C21H16FN7O. Mole weight: 401.405. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarbose sulfate | Acarbose sulfate is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. It is an inhibitor of alpha glucosidase, an enteric enzyme that releases glucose from larger carbohydrates. Acarbose sulfate decreased the Fasting Blood Glucose of DM Rats. The fasting blood glucose (FBG) in the acarbose-treated group decreased significantly at week 2 (P<0.05), week 4 (P<0.05), week 6 (P<0.05), and week 8 (P<0.05) compared to the DM group. Group: Pharmaceutical. Alternative Names: Bay-g 5421 sulfate; BAY g 5421 sulfate. CAS No. 1221158-13-9. Pack Sizes: 1mg;1g;10g. Product ID: 1221158-13-9. Molecular formula: C25H45NO22S. Mole weight: 743.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Acazicolcept | Acazicolcept is a dual ICOS/CD28 antagonist. It decreased dermal and pulmonary fibrosis and alleviated pulmonary hypertension via ICOS/CD28 blockade. Group: Pharmaceutical. Alternative Names: ALPN-101; ALPN 101; ALPN101. CAS No. 2270247-50-0. Pack Sizes: 1mg;1g;10g. Product ID: 2270247-50-0. Custom synthesis is available. Send your inquiries for more information. | London |
| Acecainide HCl | Acecainide, also known as N-acetylprocainamide and ASL 601, is a class III antiarrhythmic compound. It increases the duration of the action potential by decreasing the delayed outward potassium current, slightly decreasing the calcium current, and slightly depressing the inward rectifier potassium current. Acecainide can be given either intravenously or orally, and is eliminated primarily by renal excretion. Group: Pharmaceutical. Alternative Names: 4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide monohydrochloride; Acecainide; N-acetylprocainamide, ASL 601; ASL-601; ASL601. CAS No. 34118-92-8. Pack Sizes: 500 mg. Product ID: B0046-109971. Molecular formula: C15H24ClN3O2. Mole weight: 313.82. Custom synthesis is available. Send your inquiries for more information. | London |
| Acelarin | Acelarin is a DNA synthesis inhibitor with EC50 of 0.2 nM. Acelarin is a prodrug based on an aryloxy phosphoramidate derivative of gemcitabine. It is converted into the active metabolites dFdCDP and dFdCTP. dFdCDP can inhibit ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA replication; dFdCTP can be incorporated into DNA, resulting in premature termination of DNA replication and eventually induction of apoptosis. Phase III clinical trials for the treatment of Pancreatic cancer are on-going. Uses: Pancreatic cancer. Group: Pharmaceutical. Alternative Names: NUC-1031; NUC 1031; NUC1031; GTPL7389; GTPL 7389; GTPL-7389; SCHEMBL17171316; Benzyl (2S)-2-[({[(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methoxy}(phenoxy)phosphoryl)amino]propanoate. CAS No. 840506-29-8. Pack Sizes: 50 mg. Product ID: B2693-476645. Molecular formula: C25H27F2N4O8P. Mole weight: 580.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetylcorynoline | Acetylcorynoline, which can be extracted from the tubers of Corydalis ambigua, inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. Acetylcorynoline significantly decreases dopaminergic neuron degeneration induced by 6-hydroxydopamine in BZ555 strain; prevents α-synuclein aggregation; recovers lipid content in OW13 strain; restores food-sensing behavior, and dopamine levels; and prolongs life-span in 6-hydroxydopamine-treated N2 strain, thus showing its potential as a possible antiparkinsonian drug. Acetylcorynoline may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Uses: Antifungal/anti-inflammatory. Group: Pharmaceutical. Alternative Names: (5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate; Corynoline acetate; O-Acetylcorynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)-. CAS No. 18797-80-3. Pack Sizes: 10 mg. Product ID: B2703-464490. Molecular formula: C23H23NO6. Mole weight: 409.43. Custom synthesis is available. Send your inqui | London |
| AK-7 | AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Group: Pharmaceutical. Alternative Names: AK-7; CS-3223; GL-8955; AK7; CS3223; GL8955; AK 7; CS 3223; GL 8955. CAS No. 420831-40-9. Pack Sizes: 50 mg. Product ID: B0084-463272. Molecular formula: C19H21BrN2O3S. Mole weight: 437.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Alectinib | Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. Group: Pharmaceutical. Alternative Names: CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802. CAS No. 1256580-46-7. Pack Sizes: 200 mg. Product ID: B0084-454466. Molecular formula: C30H34N4O2. Mole weight: 482.62. Custom synthesis is available. Send your inquiries for more information. | London |
| alfa-Amyrin Acetate | Alpha-Amyrin acetate is a natural triterpenoid found in the herbs of Ervatamia divaricata, it can decrease blood engorgement time and feeding rate and decline fecundity which reduce the overall survival and reproductive capacity of the malaria vector A. stephensi. Alpha-Amyrin acetate also exhibits the activities of anti-inflammatory and antispasmodic. Uses: Anti-inflammatory; antispasmodic. Group: Pharmaceutical. Alternative Names: Urs-12-en-3-ol, acetate, (3b)- (9CI); Urs-12-en-3b-ol, acetate (6CI,7CI,8CI); 3-O-Acetyl-a-amyrin. CAS No. 863-76-3. Pack Sizes: 1mg;1g;10g. Product ID: NP6297. Molecular formula: C32H52O2. Mole weight: 468.8. Custom synthesis is available. Send your inquiries for more information. | London |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Group: Pharmaceutical. Alternative Names: AM095 (free acid); AM-095; AM 095. CAS No. 1228690-36-5. Pack Sizes: 1 g. Product ID: B2693-474408. Molecular formula: C27H24N2O5. Mole weight: 456.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Amifostine Trihydrate | Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. Group: Pharmaceutical. Alternative Names: Amifostine hydrate. CAS No. 112901-68-5. Pack Sizes: 1 g. Product ID: B2692-338520. Molecular formula: C5H15N2O3PS.3H2O. Mole weight: 268.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Anacetrapib | Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Group: Pharmaceutical. Alternative Names: MK-0859; MK 0859; MK0859; Anacetrapib. CAS No. 875446-37-0. Pack Sizes: 1 g. Product ID: B0084-181147. Molecular formula: C30H25F10NO3. Mole weight: 637.518. Custom synthesis is available. Send your inquiries for more information. | London |
| Apatinib mesylate | Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: YN968D1. CAS No. 1218779-75-9. Pack Sizes: 250 mg. Product ID: B2693-457664. Molecular formula: C25H27N5O4S. Mole weight: 493.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Arborinine | Arborinine is an alkaloid isolated from Erthela bahiensis. Arborinine was shown to inhibit splenocytes proliferation under ConA or PWM stimulation and promote apoptosis on splenocytes and thymocytes stimulated with PWM in 24h. It also decreases production of Interleukin-10 by splenocytes and thymocytes stimulated with ConA or PWM. Group: Pharmaceutical. Alternative Names: 1-hydroxy-2,3-dimethoxy-10-methylacridin-9-one. CAS No. 5489-57-6. Pack Sizes: 1 mg. Product ID: NP0701. Molecular formula: C16H15NO4. Mole weight: 285.299. Custom synthesis is available. Send your inquiries for more information. | London |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Group: Pharmaceutical. Alternative Names: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. CAS No. 91037-65-9. Pack Sizes: 100 mg. Product ID: BAT-010205. Molecular formula: C15H27N7O8. Mole weight: 433.42. Custom synthesis is available. Send your inquiries for more information. | London |
| ATB-337 | ATB-337 is a hybrid molecule of a hydrogen sulfide (H2S) donor and the nonsteroidal anti-inflammatory drugs (NSAIDs) diclofenac. H2S is a newly recognized signaling molecule with potent cytoprotective actions. Hydrogen sulfide has been involved in mediating many physiological processes, such as the maintenance of gastrointestinal mucosal defense and repair. NSAIDs are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation. Side effects depend on the specific drug, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack and kidney disease. Group: Pharmaceutical. Alternative Names: ACS 15; S-Diclofenac. CAS No. 912758-00-0. Pack Sizes: 1mg;1g;10g. Product ID: 912758-00-0. Molecular formula: C23H15NCl2O2S3. Mole weight: 504.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Avicularin | Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: Fenicularin; Quercetin 3-alpha-L-arabinofuranoside; Avicularoside. CAS No. 572-30-5. Pack Sizes: 10 mg. Product ID: NP1949. Molecular formula: C20H18O11. Mole weight: 434.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir | Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Group: Pharmaceutical. Alternative Names: Baloxavir acid; BXA; Xofluza; S-033447. CAS No. 1985605-59-1. Pack Sizes: 50 mg. Product ID: B2692-008721. Molecular formula: C24H19F2N3O4S. Mole weight: 483.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir-[d4] | Baloxavir-[d4] is an isotope compound of Baloxavir. Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Group: Pharmaceutical. CAS No. 2415027-80-2. Pack Sizes: 2 mg. Product ID: BLP-003387. Molecular formula: C24H15D4F2N3O4S. Mole weight: 487.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir marboxil | Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Group: Pharmaceutical. Alternative Names: S-033188; HY-109025. CAS No. 1985606-14-1. Pack Sizes: 50 mg. Product ID: B2692-291710. Molecular formula: C27H23F2N3O7S. Mole weight: 571.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Bavachin | Bavachin, a natural phytoestrogen found in the fruits of Psoralea corylifolia L, potentially protects cartilage from inflammation-mediated damage in joints of osteoarthritis patients through decreasing IL-1β-induced activation of IKK-IκBα-NF-κB signaling pathway. Bavachin also exhibits the activities of antioxidant, antimutagenic and weak phytoestrogen by binding and activating the estrogen receptor. Group: Pharmaceutical. Alternative Names: 4H-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten -1-yl)-;7-Hydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen -4-one. CAS No. 19879-32-4. Pack Sizes: 50 mg. Product ID: NP1866. Molecular formula: C20H20O4. Mole weight: 324.4. Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-777607 | BMS-777607 is a novel prodrug of the dual Met/VEGFR-2 inhibitor. It shows antitumor activity, inducing apoptosis and decreasing proliferation and migration. Group: Pharmaceutical. Alternative Names: BMS817378; BMS 817378; BMS-817378; BMS 777607; BMS777607; ASLAN 002; ASLAN-002; ASLAN002. CAS No. 1025720-94-8. Pack Sizes: 50 mg. Product ID: B2693-456491. Molecular formula: C25H19ClF2N4O4. Mole weight: 512.893. Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-911543 | BMS-911543 is an orally available JAK inhibitor with selectivity for JAK2. It inhibts JAK2, thereby preventing the JAK/STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. Group: Pharmaceutical. Alternative Names: BMS 911543. CAS No. 1271022-90-2. Pack Sizes: 20 mg. Product ID: B0084-457828. Molecular formula: C23H28N8O. Mole weight: 432.532. Custom synthesis is available. Send your inquiries for more information. | London |
| Boehmenan | Boehmenan is a natural lignan found in the herbs of Euphorbia hirta Linn, it inhibits PTP1B activity in a competitive manner and may also inhibit the Wnt signal by decreasing β-catenin levels. Group: Pharmaceutical. Alternative Names: 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid 3-[2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-[[[3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]oxy]methyl]-7-methoxybenzofuran-5-yl]propyl ester. CAS No. 57296-22-7. Pack Sizes: 1 mg. Product ID: NP3915. Molecular formula: C40H40O12. Mole weight: 712.8. Custom synthesis is available. Send your inquiries for more information. | London |
| Campesterol | Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. It is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. lt decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease. lt was used as standard in GC1 and HPLC2 analysis of oil samples from plants. Group: Pharmaceutical. Alternative Names: Campest-5-en-3beta-ol; Ergost-5-en-3beta-ol, (24R)-; Ergost-5-en-3-ol, (3beta,24R)-; 24α-Methyl-5-cholesten-3β-ol. CAS No. 474-62-4. Pack Sizes: 10 mg. Product ID: B0005-118922. Molecular formula: C28H48O. Mole weight: 400.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Cefepime hydrochloride hydrate | Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of gram-positive and gram-negative aerobic bacteria. Cefepime dosing was 1-4 g/day (0.5-2.0 g twice daily) for adults; ceftazidime dosing was 1-6 g/day (0.5 g every 12 hours to 2.0 g every 8 hours). A limited number of cefepime-treated patients received 2 g every 8 hours. The median length of dosing for both cefepime and ceftazidime was 7 days. Cefepime has a decreased propensity to induce beta-lactamases compared with other beta-lactam antibiotics. Cefepime has a pharmacokinetic disposition similar to that of other renally eliminated cephalosporins, with a half-life of approximately 2 hours. Cefepime has demonstrated clinical efficacy against a variety of infections, including urinary tract infections, pneumonia, and skin structure infections. Cefepime is generally well tolerated. Group: Pharmaceutical. Alternative Names: Maxipime. CAS No. 123171-59-5. Pack Sizes: 5 g. Product ID: BBF-03810. Molecular formula: C19H28Cl2N6O6S2. Mole weight: 571.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Choline Fenofibrate | Choline fenofibrate is a hydrophilic formulation of fenofibric acid that acts primarily by activating peroxisome proliferator-activated receptor alpha (PPARα). This nuclear receptor modulates the transcription of genes involved in lipid metabolism. Once activated, PPARα increases the expression of lipoprotein lipase (LPL), which hydrolyzes triglycerides in lipoproteins, thereby reducing plasma triglyceride levels. It also decreases the production of apolipoprotein C-III (ApoC-III), an inhibitor of LPL, further promoting triglyceride breakdown. Additionally, choline fenofibrate stimulates the synthesis of high-density lipoprotein cholesterol (HDL-C) by upregulating the expression of apolipoprotein A-I (ApoA-I) and apolipoprotein A-II (ApoA-II). This multifaceted mechanism helps in managing mixed dyslipidemia by lowering triglycerides and increasing HDL-C levels. Group: Pharmaceutical. Alternative Names: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate (1:1); Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid (1:1); ABT 335; FNFC; Trilipix. CAS No. 856676-23-8. Pack Sizes: 5 g. Product ID: B0084-259938. Molecular formula: C22H28ClNO5. Mole weight: 421.91. Custom synthesis is available. Send your inquiries for more information. | London |
| Cirsimaritin | Cirsimaritin is purified from the herbs of Microtea debilis. Cirsimaritin has the potential use in patients with congestive heart failure that can mitigate cardiac remodeling and left ventricular dysfunction through augmenting myocardial autophagy and decreasing matrix metalloproteinase-2&9 activities. Cirsimaritin inhibits the growth of tumor cells and induces mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), and it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt. Cirsimaritin shows moderate anti-proliferative activity against COLO-205 cells with IC 50 values of 13.1uM. Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner; support the putative application of cirsimaritin in ultraviolet photoprotection and hair coloration treatments. Group: Pharmaceutical. Alternative Names: Scrophulein; 4',5-Dihydroxy-6,7-dimethoxyflavone; 7-Methylcapillarisin. CAS No. 6601-62-3. Pack Sizes: 5 mg. Product ID: NP2021. Molecular formula: C17H14O6. Mole weight: 314.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Clidinium bromide-[d5] | Clidinium-[d5] bromide is a labelled clidinium bromide. Clidinium bromide is an anticholinergic used as an antispasmodic to reduce stomach acid and decreases intestinal spasms. Group: Pharmaceutical. Alternative Names: Clidinium-D5 bromide; Clidinium-D5 (bromide). Pack Sizes: 5 mg. Product ID: BLP-009584. Molecular formula: C22H26BrNO3. Mole weight: 437.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Corynoxine | Corynoxine is an enantiomer of Corynoxine B. It induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. By inducing autophagy, it promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. It also significantly decreased locomotor activity after oral administration to mice. Group: Pharmaceutical. Alternative Names: (16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester. CAS No. 6877-32-3. Pack Sizes: 10 mg. Product ID: NP0436. Molecular formula: C22H28N2O4. Mole weight: 384.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Cyt387 | Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 (IC50 = 11 nM and 18 nM respectively). It has been shown to decrease cancer stem cell associated tumor burden in a mouse model of human ovarian cancer. It is commonly used as a therapy for myelofibrosis. Uses: An orally bioavailable small-molecule inhibitor of janus kinases 1 and 2 (jak1/2) with potential antineoplastic activity (ic50s = 11 and 18 nm, respectively). Group: Pharmaceutical. Alternative Names: Momelotinib; N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide; CYT 11387; CYT 387; CYT-387; CYT387; CYT-0387; GS 0387. CAS No. 1056634-68-4. Pack Sizes: 50 mg. Product ID: B0084-307720. Molecular formula: C23H22N6O2. Mole weight: 414.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Dalcetrapib | Dalcetrapib is a potent CETP inhibitor that increases the HDL level and decreases the VLDL level in plasma. It exhibits cardiovascular protective property. Uses: Anticholesteremic agents. Group: Pharmaceutical. Alternative Names: JTT-705; JTT705; JTT 705; RO-4607381; RO4607381; RO 4607381; S-[2-[[1-(2-ethylbutyl)cyclohexanecarbonyl]amino]phenyl] 2-methylpropanethioate. CAS No. 211513-37-0. Pack Sizes: 100 mg. Product ID: B0084-341499. Molecular formula: C23H35NO2S. Mole weight: 389.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Darutoside | Darutoside is isolated from the herb of Siegesbeckia orientalis. It can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring collagen and promoting collagen production. Group: Pharmaceutical. Alternative Names: Darutin. CAS No. 59219-65-7. Pack Sizes: 10 mg. Product ID: NP1520. Molecular formula: C26H44O8. Mole weight: 484.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Degarelix acetate | Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist. It decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats when administered at a dose of 1 mg/kg per month. Formulations containing degarelix have been used in the treatment of advanced prostate cancer. Group: Pharmaceutical. Alternative Names: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-((S)-dihydroorotamido)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetic acid; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1); FE 200486; Gonax. CAS No. 934016-19-0. Pack Sizes: 250 mg. Product ID: BAT-016344. Molecular formula: C82H103ClN18O16.C2H4O2. Mole weight: 1692.31. Custom synthesis is available. Send your inquiries for more information. | London |
| dioctadecyl 3,3'-thiodipropionate | Dioctadecyl 3,3'-Thiodipropionate is an Antioxidants additive added to prevent degredation or oxidative decomposition of the organic polymers. Dioctadecyl 3,3'-Thiodipropionate has decreased the aging properties of poly(1-butene) in a hot air aging box. Group: Pharmaceutical. Alternative Names: Dioctadecyl thiodipropionate; Plastanox STDP; Antioxidant STDP; Cyanox STDP; Advastab 802; Propanoic acid, 3,3'-thiobis-, dioctadecyl ester. CAS No. 693-36-7. Pack Sizes: 1 kg. Product ID: B1370-075343. Molecular formula: C42H82O4S. Mole weight: 683.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Dixyrazine | Dixyrazine, a phenothiazine derivative, may decrease the incidence of postoperative vomiting without causing prolonged sedation. Group: Pharmaceutical. Alternative Names: 2-[2-[4-(2-methyl-3-phenothiazin-10-ylpropyl)piperazin-1-yl]ethoxy]ethanol; dixyrazine; Esucos. CAS No. 2470-73-7. Pack Sizes: 1mg;1g;10g. Product ID: 2470-73-7. Molecular formula: C24H33N3O2S. Mole weight: 427.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Docosahexaenoic acid | Docosahexaenoic acid (DHA) is an omega-3 fatty acid found in fish oil and a major component of excitable membranes of the retina and brain. It decreases the level of blood triglycerides and reduces the risk of cardiovascular disorders. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: (all-Z)-4,7,10,13,16,19-Docosahexaenoic Acid; DHA; Cervonic Acid; Doconexent; cis-4,7,10,13,16,19-Docosahexaenoic acid; all-cis-DHA; all-Z-Docosahexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid; all-cis-docosa-4,7,10,13,16,19-hexaenoic acid; 4,7,10,13,16,19-Docosahexaenoic acid, (all-Z)-; delta4,7,10,13,16,19-Docosahexaenoic acid; 4-cis,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid. CAS No. 6217-54-5. Pack Sizes: 1 g. Product ID: BBF-05818. Molecular formula: C22H32O2. Mole weight: 328.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Edetate trisodium | Edetate trisodium, a chelating agent that sequesters and decreases the reactivity of metal ions, is used to treat mercury and lead poisoning. Group: Pharmaceutical. Alternative Names: trisodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate; Edetate trisodium; edta trisodium; Trisodium edetate; Trisodium ethylenediaminetetraacetate; Ethylenediaminetetraacetic acid trisodium salt; 150-38-9; EDTA trisodium salt; UNII-420IP9. CAS No. 150-38-9. Pack Sizes: 1mg;1g;10g. Product ID: 150-38-9. Molecular formula: C10H13N2Na3O8. Mole weight: 358.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Group: Pharmaceutical. Alternative Names: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E)-1-[4-(Methylthio)phenyl]-3-[3,5-dimethyl-4-[(carboxydimethylmethyl)oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. CAS No. 923978-27-2. Pack Sizes: 250 mg. Product ID: B0084-074234. Molecular formula: C22H24O4S. Mole weight: 384.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Encorafenib | Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Group: Pharmaceutical. Alternative Names: LGX818; LGX-818; LGX 818; Methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate. CAS No. 1269440-17-6. Pack Sizes: 150 mg. Product ID: B0084-462563. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.011. Custom synthesis is available. Send your inquiries for more information. | London |
| Enzastaurin | Enzastaurin is a protein kinase C beta inhibitor with 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Group: Pharmaceutical. Alternative Names: 3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione; LY-317615. CAS No. 170364-57-5. Pack Sizes: 200 mg. Product ID: B0084-085618. Molecular formula: C32H29N5O2. Mole weight: 515.617. Custom synthesis is available. Send your inquiries for more information. | London |
| Epieriocalyxin A | Epieriocalyxin A (EpiA), a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. Western blot results showed that both JNK and ERK1/2 activation was decreased after Epieriocalyxin A treatment in a dose-dependent manner. Epieriocalyxin A increased the expression of caspase 3 and Bax, and decreased Bcl2 expression. Our results suggest that Epieriocalyxin A is a novel compound that induces colon cancer apoptosis. Epieriocalyxin A could be a potential drug for colon cancer therapy in the future. Uses: Anti-cancer. Group: Pharmaceutical. Alternative Names: Spiro[1H-7,9a-methanolocyclohepta[c]pyran-4(3H),1'-[3]cyclohexene]-6'-carboxaldehyde, 4a,5,6,7,8,9-hexahydro-5',5',8-trimethyl-1,2',9-trioxo-, (1'S,4aS,6'R,7R,8R,9aS)-. CAS No. 191545-24-1. Pack Sizes: 1 mg. Product ID: NP1352. Molecular formula: C20H24O5. Mole weight: 344.4. Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
