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| Product | Description | |
|---|---|---|
| Aceclofenac-[d2] | Labelled form of Aceclofenac. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. It works by blocking the action of a substance in the body called cyclo-oxygenase. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003193. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Aceclofenac-[d4] | Labelled form of Aceclofenac. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. It works by blocking the action of a substance in the body called cyclo-oxygenase. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003194. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aceclofenac-[d7] | Labelled form of Aceclofenac. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. It works by blocking the action of a substance in the body called cyclo-oxygenase. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003195. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adapalene | Adapalene is more active than indomethacin, betamethasone valerate, tretinoin, isotretinoin or etretinate in inhibiting lipoxygease activity, but it has little activity against cyclo-oxygenase. Group: Pharmaceutical. CAS No. 106685-40-9. Pack Sizes: 500 mg. Product ID: B0046-463772. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Auranofin | Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Uses: Auranofin inhibits various leukocyte activation pathways at multiple sites. Group: Pharmaceutical. CAS No. 34031-32-8. Pack Sizes: 1 g. Product ID: B2693-397760. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bryonolic acid | Bryonolic acid isolated from the herbs of Sandoricum indicum. It induces a obviously increase in the expression of a phase 2 response enzyme and heme oxygenase 1 (HO-1) in a dose-dependent manner. Uses: Anti-allergic activity; anti-inflammatory and antioxidant activities. Group: Pharmaceutical. CAS No. 24480-45-3. Pack Sizes: 1 mg. Product ID: NP6506. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desoxo-narchinol A | Desoxo-narchinol A is a sesquiterpenoid isolated from Nardostachys jatamansi. Desoxo-narchinol A upregulates nuclear transcription factor erythroid-2-related factor 2/heme oxygenase-1 signaling and exhibits anti-neuroinflammatory effects. Group: Pharmaceutical. CAS No. 53859-06-6. Pack Sizes: 1 mg. Product ID: NP5924. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Iguratimod | Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Group: Pharmaceutical. CAS No. 123663-49-0. Pack Sizes: 250 mg. Product ID: B0084-056331. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Group: Pharmaceutical. CAS No. 1474034-05-3. Pack Sizes: 20 mg. Product ID: B0084-462776. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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