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An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Group: Pharmaceutical. Alternative Names: Safinamide Impurity 4; (R)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}alaninamide. CAS No. 174756-44-6. Pack Sizes: 1 mg. Product ID: B1605-458661. Molecular formula: C17H19FN2O2. Mole weight: 302.349. Custom synthesis is available. Send your inquiries for more information.
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3,5-dipyridyl-1,2,4-triazole
One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Group: Pharmaceutical. Alternative Names: 4,4'-(1H-1,2,4-triazole-3,5-diyl)dipyridine; 3,5-Di(4-pyridyl)-1,2,4-triazole. CAS No. 4329-78-6. Pack Sizes: 500 mg. Product ID: B2694-484333. Molecular formula: C12H9N5. Mole weight: 223.24. Custom synthesis is available. Send your inquiries for more information.
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Allopurinol
Allopurinol is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. Uses: Antimetabolites; antimetabolites, antineoplastic; enzyme inhibitors; gout suppressants. Group: Pharmaceutical. Alternative Names: Allopurinol. CAS No. 315-30-0. Pack Sizes: 1mg;1g;10g. Product ID: NP2980. Molecular formula: C5H4N4O. Mole weight: 136.11. Custom synthesis is available. Send your inquiries for more information.
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AZ7371
AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Group: Pharmaceutical. Alternative Names: AZ-7371; AZ 7371; TBA-7371; DprE1-IN-1. CAS No. 1494675-86-3. Pack Sizes: 50 mg. Product ID: B2693-470868. Molecular formula: C18H21N5O3. Mole weight: 355.4. Custom synthesis is available. Send your inquiries for more information.
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Blumeatin
Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Group: Pharmaceutical. Alternative Names: 5,3',5'-Trihydroxy-7-methoxyflavanone; 2-(3,5-Dihydroxyphenyl)-5-hydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one. CAS No. 118024-26-3. Pack Sizes: 10 mg. Product ID: B1370-267733. Molecular formula: C16H14O6. Mole weight: 302.28. Custom synthesis is available. Send your inquiries for more information.
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Desciclovir
Desciclovir is a prodrug of the antiherpetic agent acyclovir (ACV) and converted into ACV by xanthine oxidase in humans. Group: Pharmaceutical. Alternative Names: 6-Deoxyacyclovir; BW A515U. CAS No. 84408-37-7. Pack Sizes: 1mg;1g;10g. Product ID: 84408-37-7. Molecular formula: C8H11N5O2. Mole weight: 209.208. Custom synthesis is available. Send your inquiries for more information.
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Echitovenidine
Echitovenidine is an alkaloid isolated from the fruits of Alstonia venenata. In vitro and in vivo studies revealed that echitovenidine has an inhibitory effect on monoamine oxidase. Group: Pharmaceutical. Alternative Names: Aspidospermidine-3-carboxylic acid, 2,3-didehydro-20-((3-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (5-alpha,12-beta,19-alpha,20R)-. CAS No. 7222-35-7. Pack Sizes: 1 mg. Product ID: NP0753. Molecular formula: C26H32N2O4. Mole weight: 436.552. Custom synthesis is available. Send your inquiries for more information.
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Escitalopram
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Group: Pharmaceutical. Alternative Names: (S)-Citalopram; S-(+)-Citalopram; Seroplex. CAS No. 128196-01-0. Pack Sizes: 500 mg. Product ID: B2693-461840. Molecular formula: C20H21FN2O. Mole weight: 324.39. Custom synthesis is available. Send your inquiries for more information.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: Ethyl 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate. CAS No. 161798-02-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3334. Molecular formula: C14H12N2O3S. Mole weight: 288.33. Custom synthesis is available. Send your inquiries for more information.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate. CAS No. 160844-75-7. Pack Sizes: 1mg;1g;10g. Product ID: NP3333. Molecular formula: C18H20N2O3S. Mole weight: 344.44. Custom synthesis is available. Send your inquiries for more information.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate. CAS No. 161798-01-2. Pack Sizes: 1mg;1g;10g. Product ID: NP3332. Molecular formula: C14H13NO4S. Mole weight: 291.33. Custom synthesis is available. Send your inquiries for more information.
ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: ethyl 2-(3-formyl-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylate. CAS No. 2230270-05-8. Pack Sizes: 25 mg. Product ID: B1370-377731. Molecular formula: C18H20N2O3S. Mole weight: 344.43. Custom synthesis is available. Send your inquiries for more information.
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Febuxostat
Febuxostat is a xanthine oxidase/xanthine dehydrogenase inhibitor used to treat hyperuricemia and chronic gout. Uses: Gout suppressants. Group: Pharmaceutical. Alternative Names: TMX-67; TEI-6720; TMX 67; TEI 6720; TMX67; TEI6720; Uloric; Adenuric; 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid; 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic Acid. CAS No. 144060-53-7. Pack Sizes: 1mg;1g;10g. Product ID: NP3488. Molecular formula: C16H16N2O3S. Mole weight: 316.37. Custom synthesis is available. Send your inquiries for more information.
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Febuxostat Amide Impurity
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid. CAS No. 1239233-86-3. Pack Sizes: 25 mg. Product ID: B0024-471481. Molecular formula: C16H18N2O4S. Mole weight: 334.4. Custom synthesis is available. Send your inquiries for more information.
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Febuxostat-[d7]
Febuxostat-[d7] is the labelled analogue of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: Febuxostat D7; 2-[3-Cyano-4-(2-methylpropoxyphenyl]-4-methyl-5-thiazolecarboxylic Acid-d7; 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic Acid-d7; TEI 6720-d7; TMX 67-d7; 2-(3-Cyano-4-{[2-(2H3)methyl(2,3,3,3-2H4)propyl]oxy}phenyl)-4-methyl-1,3-thiazole-5-carboxylic acid. CAS No. 1285539-74-3. Pack Sizes: 10 mg. Product ID: BLP-012352. Molecular formula: C16H9D7N2O3S. Mole weight: 323.42. Custom synthesis is available. Send your inquiries for more information.
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Febuxostat Impurity 23
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. CAS No. 2073891-59-3. Pack Sizes: 2 mg. Product ID: B2694-338784. Molecular formula: C15H13NO5S. Mole weight: 319.33. Custom synthesis is available. Send your inquiries for more information.
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Isovitexin
Isovitexin, a food phytochemical contained in dietary rice products, or as a natural plant flavonoid isolated from the seeds of Vitex trifolia L, suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages. Isovitexin exhibits anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating HO-1/Nrf2 pathways. Isovitexin can inhibit xanthine oxidase with an IC50 value of 15.2 microM, and it may protect cells from oxidative stress. Group: Pharmaceutical. Alternative Names: Saponaretin; Homovitexin; (1S)-1,5-anhydro-1-[5,7-dihydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol; 4H-1-Benzopyran-4-one, 6-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 6-β-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Flavone, 6-β-D-glucopyranosyl-4',5,7-trihydroxy-; Homovitexin; 6-C-Glucosylapigenin; 6-C-β-D-Glucopyranosylapigenin; Apigenin 6-C-β-D-glucoside; Apigenin 6-C-β-glucopyranoside; Apigenin-6-C-glucoside; Apigenin-6-C-β-D-glucopyranoside; Avroside; Isoavroside; Isovitexin (C-6 isomer); Saponaretin. CAS No. 38953-85-4. Pack Sizes: 100 mg. Product ID: NP1807. Molecular formula: C21H20O10. Mole weight: 432.38. Custom synthesis is available. Send your inquiries for more information.
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Lumasiran
Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Group: Pharmaceutical. Alternative Names: ALN-G01; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) (1:1). CAS No. 1834610-13-7. Pack Sizes: 5 mg. Product ID: B1370-072716. Molecular formula: C530H712F10N173O320P43S6. Mole weight: 16,340 Da. Custom synthesis is available. Send your inquiries for more information.
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Moclobemide
Moclobemide is a reversible monoamine oxidase A (MAO-A) inhibitor, displaying antidepressive activity. Group: Pharmaceutical. Alternative Names: Ro11-1163; Ro 11-1163; Ro111163; Ro-111163; Ro 111163; Moclobemide; brand name: Amira; Aurorix; Clobemix; Depnil; Manerix; 4-chloro-N-(2-morpholin-4-ylethyl)benzamide. CAS No. 71320-77-9. Pack Sizes: 100 mg. Product ID: B0084-075760. Molecular formula: C13H17ClN2O2. Mole weight: 268.74. Custom synthesis is available. Send your inquiries for more information.
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p-[N-(p-Fluorophenyl)formimidoyl]phenol
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. Alternative Names: 4-(4-HYDROXYBENZYLIDENE) FLUORO ANILINE; 4-(((4-FLUOROPHENYL)IMINO)METHYL)PHENOL; 2-(4 ' -Hydrophenyl)-4-fluorobenyl imine; alpha-4-Fluorophenylimino-p-cresol; (E)-4-((4-Fluorophenylimino)methyl)phenol; 4-fluoro-N-(hydroxyphenyl)methylene-benzenamine; E2:4{[(4. CAS No. 3382-63-6. Pack Sizes: 2 mg. Product ID: B2694-011490. Molecular formula: C13H10FNO. Mole weight: 215.22. Custom synthesis is available. Send your inquiries for more information.
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Procyanidin A2
(+)-Proanthocyanidin A2 is a polyphenol oxidase (PPO) substrates isolated from grape seeds (Vitis vinifera L). Proanthocyanidins represent one of the major groups of plant polyphenols. A2 could isolated from the acetone-water extract (7:3, v/v) of horse chestnut seed shells (Aesculus hyppocastanum), after extraction with ethyl acetate, by combined LH-20 chromatography and TLC on Silicagel 60 plates. Group: Pharmaceutical. Alternative Names: 8,?14-Methano-2H,?14H-1-benzopyrano[7,?8-d]?[1,?3]?benzodioxocin-3,?5,?11,?13,?15-pentol, 2,?8-bis(3,?4-dihydroxyphenyl)?-3,?4-dihydro-, (2R,?3R,?8S,?14R,?15R)?-; 8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol, 2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, [2R-(2α,3α,8β,14β,15R*)]-; (2R,3R,8S,14R,15R)-2,8-Bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol; (+)-Epicatechin-(4β-8,2β-O-7)-epicatechin; Dimeric catechin. CAS No. 41743-41-3. Pack Sizes: 5 mg. Product ID: NP1976. Molecular formula: C30H24O12. Mole weight: 576.5. Custom synthesis is available. Send your inquiries for more information.
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Protoporphyrin IX
Created by the enzyme protoporphyrinogen oxidase, protoporphyrin IX is an important precursor to biologically essential prosthetic groups. Uses: Metabolism of porphyrin. Group: Pharmaceutical. Alternative Names: Protoporphyrin; 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid. CAS No. 553-12-8. Pack Sizes: 2 g. Product ID: B2693-071431. Molecular formula: C34H34N4O4. Mole weight: 562.66. Custom synthesis is available. Send your inquiries for more information.
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Rasagiline mesylate
Rasagiline (N-propargyl-1-(R)-aminoindan) is a novel, highly potent irreversible monoamine oxidase (MAO)-B inhibitor, anti-Parkinsonian drug. Uses: Neuroprotective agents. Group: Pharmaceutical. Alternative Names: TVP-1012; TVP 1012; TVP1012. CAS No. 161735-79-1. Pack Sizes: 500 mg. Product ID: NP3667. Molecular formula: C12H13N.CH4O3S. Mole weight: 267.34. Custom synthesis is available. Send your inquiries for more information.
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Safinamide Impurity 5
An impurity of Safinamide, a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. Alternative Names: (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanoic acid; (2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanoic acid. CAS No. 1160513-60-9. Pack Sizes: 25 mg. Product ID: B2694-479401. Molecular formula: C17H18FNO3. Mole weight: 303.34. Custom synthesis is available. Send your inquiries for more information.
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Safinamide Impurity 8
An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. Alternative Names: 4-[(3-Fluorophenyl)methoxy]benzenemethanol. CAS No. 690969-16-5. Pack Sizes: 1 g. Product ID: B2694-479404. Molecular formula: C14H13FO2. Mole weight: 232.26. Custom synthesis is available. Send your inquiries for more information.
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Sappanchalcone
Sappanchalcone is a natural flavonoid extracted from Caesalpinia sappan. It exhibits cytoprotective activity and anti-inflammatory effects, which can reduce clinical arthritis. Sappanchalcone is also a xanthine oxidase inhibitor. Uses: Cytoprotective, anti-inflammatory. Group: Pharmaceutical. Alternative Names: (2E)-3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-Methoxyphenyl)-2-propen-1-one; 3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-Methoxyphenyl)prop-2-en-1-one. CAS No. 94344-54-4. Pack Sizes: 5 mg. Product ID: NP0934. Molecular formula: C16H14O5. Mole weight: 286.3. Custom synthesis is available. Send your inquiries for more information.
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Tedizolid Phosphate
Torezolid phosphate is a novel oxazolidinone for gram-positive infections, with IC50 of 8.7 μM and 5.7 μM for monoamine oxidase (MAO)-A and MAO-B, respectively. It is commonly used for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by several Gram-positive bacteria. Uses: The treatment of acute bacterial skin and skin structure infections (absssi). Group: Pharmaceutical. Alternative Names: TR-701FA; Torezolid phosphate; Sivextro; Tedizolid (phosphate); UNII-O7DRJ6R4DW. CAS No. 856867-55-5. Pack Sizes: 250 mg. Product ID: B0084-465276. Molecular formula: C17H16FN6O6P. Mole weight: 450.32. Custom synthesis is available. Send your inquiries for more information.
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Tranylcypromine hydrochloride
Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and human liver microsomes, respectively. Group: Pharmaceutical. Alternative Names: (1R,2S)-2-phenylcyclopropan-1-amine;hydrochloride. CAS No. 1986-47-6. Pack Sizes: 1 g. Product ID: B0084-462918. Molecular formula: C9H12ClN. Mole weight: 169.65. Custom synthesis is available. Send your inquiries for more information.
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