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| Product | Description | |
|---|---|---|
| Glucose Oxidase from Aspergillus niger, low catalase | 250mg Pack Size. Group: Analytical Reagents, Biochemicals. CAS No. 9001-37-0. Prepack ID : 11547451-250mg. |  |
| Lipoxidase | 100mg Pack Size. Group: Biochemicals, Research Organics & Inorganics. CAS No. 9029-60-1. Prepack ID : 14946502-100mg. | |
| 10-Acetyl-3,7-dihydroxyphenoxazine | 10-Acetyl-3,7-dihydroxyphenoxazine is a sensitive and stable substrate for horseradish peroxidase (HRP). It reacts with H2O2 to produce the fluorescent compound resorufin that can be used for detection of H2O2. Group: Pharmaceutical. CAS No. 119171-73-2. Pack Sizes: 1 g. Product ID: B0001-161736. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| (1S,3R)-RSL3 | (1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with EC50 of 10 μM in cellular assay. It binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Group: Pharmaceutical. CAS No. 1219810-16-8. Pack Sizes: 100 mg. Product ID: B0084-474402. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (2R) -2- [ [4- [ (3-fluorophenyl) methoxy] phenyl] methylamino] propanamide | An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Group: Pharmaceutical. CAS No. 174756-44-6. Pack Sizes: 1 mg. Product ID: B1605-458661. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3,5-dipyridyl-1,2,4-triazole | One of the impurities of Topiroxostat, which is a xanthine oxidase inhibitor and has been found to be effective in the treatment of gout and hyperuricemia. Group: Pharmaceutical. CAS No. 4329-78-6. Pack Sizes: 500 mg. Product ID: B2694-484333. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Formylpterin | 6-Formylpterin is a pteridine derivative that acts as a xanthine oxidase inhibitor. Group: Pharmaceutical. CAS No. 712-30-1. Pack Sizes: 100 mg. Product ID: B0084-149631. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac9-25 | Ac9-25 is a N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Group: Pharmaceutical. CAS No. 284040-76-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016353. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac9-25 acetate | Ac9-25 acetate is an N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016203. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetovanillone-[d3] | Acetovanillone-[d3]. Uses: A naturally abundant compound, isolated from a variety of plant sources. it is an effective inhibitor of nadph oxidase, and thus shows antioxidant behaviour without interfering with other aspects of the immune system. Group: Pharmaceutical. CAS No. 80404-23-5. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-010669. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZ7371 | AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Group: Pharmaceutical. CAS No. 1494675-86-3. Pack Sizes: 50 mg. Product ID: B2693-470868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Blumeatin | Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Group: Pharmaceutical. CAS No. 118024-26-3. Pack Sizes: 10 mg. Product ID: B1370-267733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ebselen | Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Group: Pharmaceutical. CAS No. 60940-34-3. Pack Sizes: 1 g. Product ID: B2693-072972. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Echitovenidine | Echitovenidine is an alkaloid isolated from the fruits of Alstonia venenata. In vitro and in vivo studies revealed that echitovenidine has an inhibitory effect on monoamine oxidase. Group: Pharmaceutical. CAS No. 7222-35-7. Pack Sizes: 1 mg. Product ID: NP0753. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Escitalopram | Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Group: Pharmaceutical. CAS No. 128196-01-0. Pack Sizes: 500 mg. Product ID: B2693-461840. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Febuxostat Amide Impurity | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. CAS No. 1239233-86-3. Pack Sizes: 25 mg. Product ID: B0024-471481. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Febuxostat-[d7] | Febuxostat-[d7] is the labelled analogue of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. CAS No. 1285539-74-3. Pack Sizes: 10 mg. Product ID: BLP-012352. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Febuxostat Impurity 23 | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. CAS No. 2073891-59-3. Pack Sizes: 2 mg. Product ID: B2694-338784. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hypaphorine | Hypaphorine is an indole-3-acetic acid antagonist which specifically competes with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases. Group: Pharmaceutical. CAS No. 487-58-1. Pack Sizes: 10 mg. Product ID: B2703-465879. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isovitexin | Isovitexin, a food phytochemical contained in dietary rice products, or as a natural plant flavonoid isolated from the seeds of Vitex trifolia L, suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages. Isovitexin exhibits anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating HO-1/Nrf2 pathways. Isovitexin can inhibit xanthine oxidase with an IC50 value of 15.2 microM, and it may protect cells from oxidative stress. Group: Pharmaceutical. CAS No. 29702-25-8. Pack Sizes: 100 mg. Product ID: NP1807. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lumasiran | Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Group: Pharmaceutical. CAS No. 1834610-13-7. Pack Sizes: 5 mg. Product ID: B1370-072716. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lycopene | Lycopene, in the concentration used, is not toxic and also its health benefits in adipose tissue may play a role against obesity-related complications. Lycopene in tomato puree has decreased indicating an indirect effect on lycopene stability caused by high concentration of hydrogen peroxide and the activation of peroxidase enzymes leading to the reduction of ascorbic acid and its regenerative action towards lycopene. Besides, Lycopene protected β-carotene against isomerization during reactions with singlet oxygen and radicals. These findings can explain the pattern of carotenoid isomers analyzed in fruits and vegetables, where lycopene containing samples showed higher (all-E)/(9Z)-β-carotene ratios, and also in in vivo samples such as human blood plasma. Lycopene can be used as pigment in food processing, and is also used as raw material of antioxidant health food. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 502-65-8. Pack Sizes: 1 g. Product ID: B0005-464994. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Moclobemide | Moclobemide is a reversible monoamine oxidase A (MAO-A) inhibitor, displaying antidepressive activity. Group: Pharmaceutical. CAS No. 71320-77-9. Pack Sizes: 100 mg. Product ID: B0084-075760. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Moclobemide Impurities | Moclobemide Impurities play a significant role in quality control and analysis within the pharmaceutical industry, particularly for antidepressant medications. They are critical in ensuring the efficacy and safety of Moclobemide, a monoamine oxidase inhibitor used to treat depression and social anxiety disorder. Analyzing these impurities aids in maintaining drug purity and regulatory compliance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MPO-IN-28 | MPO-IN-28 is a myeloperoxidase (MPO) inhibitor with IC50 of 44 nM. Group: Pharmaceutical. CAS No. 37836-90-1. Pack Sizes: 50 mg. Product ID: B1370-381586. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ORY-1001 dihydrochloride | ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B > 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Group: Pharmaceutical. CAS No. 1431326-61-2. Pack Sizes: 50 mg. Product ID: B0084-470857. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PF-06282999 | PF-06282999 is a selective myeloperoxidase Inhibitor originate by Pfizer. It showed good oral pharmacokinetics in preclinical species and robust irreversible inhibition of plasma MPO activity. In Mar 2015, Pfizer terminated phase I trial for the treatment of Acute coronary syndromes in Healthy volunteers in USA. Uses: Acute coronary syndromes. Group: Pharmaceutical. CAS No. 1435467-37-0. Pack Sizes: 10 mg. Product ID: B0084-474817. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PF-1355 | PF-1355 is a selective, mechanism-based inhibitor of myeloperoxidase (MPO) (IC50 = 1.5 μM in LPS-stimulated human whole blood) with excellent selectivity for MPO without disrupting a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. PF-1355 was used to test the hypothesis that MPO activity is a critical mediator of disease activity in immune complex vasculitis mouse models, and to support the confidence in rationale for this mechanism as a therapeutic approach to treat related human condition such as alleviating tissue injury caused by Goodpasture syndrome and pulmonary vasculitis induced by immune complexes. Group: Pharmaceutical. CAS No. 1435467-38-1. Pack Sizes: 50 mg. Product ID: B0084-474818. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| p-[N-(p-Fluorophenyl)formimidoyl]phenol | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Group: Pharmaceutical. CAS No. 3382-63-6. Pack Sizes: 2 mg. Product ID: B2694-011490. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Procyanidin A2 | (+)-Proanthocyanidin A2 is a polyphenol oxidase (PPO) substrates isolated from grape seeds (Vitis vinifera L). Proanthocyanidins represent one of the major groups of plant polyphenols. A2 could isolated from the acetone-water extract (7:3, v/v) of horse chestnut seed shells (Aesculus hyppocastanum), after extraction with ethyl acetate, by combined LH-20 chromatography and TLC on Silicagel 60 plates. Group: Pharmaceutical. CAS No. 41743-41-3. Pack Sizes: 5 mg. Product ID: NP1976. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Protoporphyrin IX | Created by the enzyme protoporphyrinogen oxidase, protoporphyrin IX is an important precursor to biologically essential prosthetic groups. Uses: Metabolism of porphyrin. Group: Pharmaceutical. CAS No. 553-12-8. Pack Sizes: 2 g. Product ID: B2693-071431. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Purine Derivatives | Purine Derivatives represent a cornerstone in biomedical sciences, vital for synthesizing therapeutic agents like allopurinol, targeting gout via xanthine oxidase inhibition. Their critical functionality extends to anticancer and antiviral domains, offering potential solutions for managing viral infections, such as HIV and hepatitis, thus fortifying therapeutic interventions across diverse pathologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rasagiline mesylate | Rasagiline (N-propargyl-1-(R)-aminoindan) is a novel, highly potent irreversible monoamine oxidase (MAO)-B inhibitor, anti-Parkinsonian drug. Uses: Neuroprotective agents. Group: Pharmaceutical. CAS No. 161735-79-1. Pack Sizes: 500 mg. Product ID: NP3667. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rehmannic acid | Rehmannic acid is a natural triterpenoid found in the herbs of Lantana camara. Rehmannic acid has inhibit succinoxidase activity. Group: Pharmaceutical. CAS No. 467-81-2. Pack Sizes: 1 mg. Product ID: NP6783. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Resveratrol | Resveratrol is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity), mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity), and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose-and time-dependent manner. Resveratrol is a natural compound used in cosmetic materials. It is widely used in anti-aging and wrinkle removal, whitening and whitening spots, antibacterial and anti-inflammatory, oil control and acne, anti-allergy and analgesia, scar repair, hair care and other products, and it is compatible with lotion cream formula, gel formula and water formula. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 501-36-0. Pack Sizes: 20 g. Product ID: BBF-03781. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Safinamide Impurity 5 | An impurity of Safinamide, a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. CAS No. 1160513-60-9. Pack Sizes: 25 mg. Product ID: B2694-479401. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Safinamide Impurity 8 | An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Group: Pharmaceutical. CAS No. 690969-16-5. Pack Sizes: 1 g. Product ID: B2694-479404. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sappanchalcone | Sappanchalcone is a natural flavonoid extracted from Caesalpinia sappan. It exhibits cytoprotective activity and anti-inflammatory effects, which can reduce clinical arthritis. Sappanchalcone is also a xanthine oxidase inhibitor. Uses: Cytoprotective, anti-inflammatory. Group: Pharmaceutical. CAS No. 94344-54-4. Pack Sizes: 5 mg. Product ID: NP0934. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tedizolid Phosphate | Torezolid phosphate is a novel oxazolidinone for gram-positive infections, with IC50 of 8.7 μM and 5.7 μM for monoamine oxidase (MAO)-A and MAO-B, respectively. It is commonly used for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by several Gram-positive bacteria. Uses: The treatment of acute bacterial skin and skin structure infections (absssi). Group: Pharmaceutical. CAS No. 856867-55-5. Pack Sizes: 250 mg. Product ID: B0084-465276. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Terbinafine hydrochloride | Terbinafine HCl is a hydrochloride salt of terbinafine that is a synthetic allylamine antifungal and a squalene epoxidase inhibitor with an IC50 of 30 nM for Candida albicans. Group: Pharmaceutical. CAS No. 78628-80-5. Pack Sizes: 10 g. Product ID: NP3441. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tranylcypromine hydrochloride | Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and human liver microsomes, respectively. Group: Pharmaceutical. CAS No. 1986-47-6. Pack Sizes: 1 g. Product ID: B0084-462918. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tyramine Impurities | Tyramine Impurities, as trace by-products in synthesizing tyramine-associated compounds, assume considerable importance in scientific inquiry. Their pertinence lies in neurotransmitter modulation, elucidating conditions such as hypertension and migraines through monoamine oxidase influence, thus emerging as potential strategic tools for neurovascular and cardiovascular therapeutic development. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Xanthine Impurities | Xanthine Impurities are minor components in pharmaceutical formulations, playing a crucial role in drug testing and stability analysis. They are particularly relevant in the context of xanthine oxidase inhibitors, which are used to treat conditions like gout and hyperuricemia. Monitoring these impurities ensures the efficacy and safety of xanthine-containing drugs. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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