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1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) is a liposome formulation for cationic lipid DOTAP. DOTAP can be used for the efficiency of DNA transfection, including yeast artificial chromosomes (YAC) transfection to eukaryotic cells used in transient or stable gene expression, and also suitable for efficient will other negatively charged molecules, such as RNA, oligonucleotides, and glutamic acid, the ribosome protein (RNP) complex, and protein, transferred to the study sample of mammalian cells. Group: Pharmaceutical. Alternative Names: DOTAP Transfection Reagent; DOTAP-MS; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate; DOTAP methosulfate; 18:1 TAP (DOTAP, MS Salt); n-(2,3-dioleoyloxy-1-propyl) trimethylammonium methyl sulfate. CAS No. 144189-73-1. Pack Sizes: 500 mg. Product ID: BAT-006359. Molecular formula: C43H83NO8S. Mole weight: 774.19. Custom synthesis is available. Send your inquiries for more information.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 4-(4,4-Difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)-butyric Acid. CAS No. 878674-84-1. Pack Sizes: 10 mg. Product ID: B0245-044224. Molecular formula: C17H21BF2N2O2. Mole weight: 334.17. Custom synthesis is available. Send your inquiries for more information.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 4,4-Difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene. CAS No. 194235-40-0. Pack Sizes: 1 g. Product ID: B1370-285100. Molecular formula: C19H19BF2N2. Mole weight: 324.18. Custom synthesis is available. Send your inquiries for more information.
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2,6-Diiodo-1,3,5,7,8-pentaethyl-BODIPY
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. CAS No. 1031443-55-6. Pack Sizes: 50 mg. Product ID: B1370-285124. Molecular formula: C14H15BF2I2N2. Mole weight: 513.9. Custom synthesis is available. Send your inquiries for more information.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 5,5-Difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 1083009-44-2. Pack Sizes: 10 mg. Product ID: B2708-285125. Molecular formula: C19H17BF2I2N2. Mole weight: 575.974. Custom synthesis is available. Send your inquiries for more information.
London
2'-O-(2-Methoxyethyl)adenosine
It is a derivative of adenosine that acts as a building block for crosslinking oligonucleotides. Group: Pharmaceutical. Alternative Names: (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol; Adenosine, 2'-O-(2-methoxyethyl)-; 2'-O-methoxyethyl Adenosine; 2'-O-MOE-A; 2'-O-MOE-Adenosine; 2'-O-MOE-rA. CAS No. 168427-74-5. Pack Sizes: 1 g. Product ID: B2706-051664. Molecular formula: C13H19N5O5. Mole weight: 325.32. Custom synthesis is available. Send your inquiries for more information.
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2'-O-(2-Methoxyethyl)guanosine
It is a guanosine derivative as a building block for crosslinking oligonucleotides. Group: Pharmaceutical. Alternative Names: Guanosine, 2'-O-(2-methoxyethyl)-; 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one; 2'-MOE-rG; 2'-O-Methoxyethyl-guanosine; 2'-O-MOE-rG. CAS No. 473278-54-5. Pack Sizes: 1 g. Product ID: B2706-120687. Molecular formula: C13H19N5O6. Mole weight: 341.32. Custom synthesis is available. Send your inquiries for more information.
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2'-OMe-dmf-G-CE Phosphoramidite
2'-OMe-dmf-G-CE Phosphoramidite, a vital compound in the biomedicine industry, is leveraged for the crucial synthesis of oligonucleotides. These tiny yet potent molecules are widely utilized in treating an array of afflictions such as cancer, viral infections, and genetic disorders. Devised to heighten the steadfastness and efficacy of oligonucleotides, our product offers patients the potential for better therapeutic outcomes. Group: Pharmaceutical. Alternative Names: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methylguanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; DMT-2'-O-Me-G(dmf)-CE Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-OMe-G-CE Phosphoramidite; 2'-O-Methyl Guanosine (n,n-dmf) CED phosphoramidite. CAS No. 128219-77-2. Pack Sizes: 1 g. Product ID: B2706-004449. Molecular formula: C44H55N8O8P. Mole weight: 854.92. Custom synthesis is available. Send your inquiries for more information.
London
2'-OMe-G(iBu)-3'-phosphoramidite
2'-OMe-G(iBu)-3'-phosphoramidite is a modified phosphoramidite designed for the synthesis of stable and efficient RNA oligonucleotides. The protective groups and modifications, such as 5'-O-DMTr, N2-isobutyryl, and 2'-O-methyl, enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in producing antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications. Group: Pharmaceutical. Alternative Names: 5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite; 2'-OMe-iBu-G CE phosphoramidite; 5'-O-DMT-2'-O-Me-G(iBu) phosporamidite; DMT-2'-O-Me-rG(iBu) amidite; N2-Isobutyryl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-Guanosine-3'-CE-Phosphoramidite. CAS No. 150780-67-9. Pack Sizes: 5 g. Product ID: B2706-084599. Molecular formula: C45H56N7O9P. Mole weight: 869.94. Custom synthesis is available. Send your inquiries for more information.
London
2'-O-Propargyl A(Bz)-3'-phosphoramidite
2'-O-Propargyl A(Bz)-3'-phosphoramidite, a highly versatile compound, plays a pivotal role in the biomedical sector for crafting customized oligonucleotides. Its exceptional propargyl and benzoyl functionalities facilitate seamless bonding with a wide range of biomolecules. Hailed for its profound impact in drug discovery, this product aids in the creation of nucleic acid-driven therapeutics, notably those combating diverse ailments such as cancer, viral infections, and neurodegenerative disorders. Its paramount significance in the field underscores the significance of this remarkable compound. Group: Pharmaceutical. Alternative Names: N4-Bz-5'-O-DMTr-2'-O-propargyladenosine-3'-CED-phosphoramidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]-2'-O-2-propyn-1-yl-adenosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)phosphoramidite]. CAS No. 171486-59-2. Pack Sizes: 500 mg. Product ID: B2706-337734. Molecular formula: C50H54N7O8P. Mole weight: 911.98. Custom synthesis is available. Send your inquiries for more information.
London
2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite
2'-tBDSilyl Adenosine (n-PAC) CED Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It incorporates a 2'-tert-butyldimethylsilyl (tBDSilyl) group onto the adenosine (A) nucleoside at the 2'-position. Additionally, it features a nitrilotriacetic acid (n-PAC) group for chelating metal ions and a controlled-efficiency (CED) phosphoramidite for efficient incorporation during solid-phase synthesis. This reagent enables the production of modified RNA oligonucleotides with improved stability and functionality, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies. Group: Pharmaceutical. Alternative Names: PAC-rA CEP; N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, 5'-O-. CAS No. 121058-86-4. Pack Sizes: 1 g. Product ID: B1370-008561. Molecular formula: C54H68N7O9PSi. Mole weight: 1018.22. Custom synthesis is available. Send your inquiries for more information.
The biphenyl-P-oxide compound, widely applied in biomedicine such as drug discovery, serves as a palladium-catalyzed cross-coupling reaction ligand. This compound presents tremendous versatility in its usability as it is instrumental in the oligonucleotide synthesis and the production of numerous bioactive molecules. Group: Pharmaceutical. Alternative Names: [3S-(1Z,3α,5β)]-[2-[3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethyl]diphenylphosphine Oxide; Phosphine oxide, [2-[3,5-bis[[(1,1-dimethylethyl)dimethylsily]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-, [3S-(1Z,3α,5β)]-; Tert-butyl-[(1R,3S,5Z)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2-diphenylphosphorylethylidene)-4-methylidenecyclohexyl]oxy-dimethylsilane; ((Z)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethyl)diphenylphosphine oxide. CAS No. 81522-68-1. Pack Sizes: 100 mg. Product ID: B0001-098901. Molecular formula: C33H51O3PSi2. Mole weight: 582.9. Custom synthesis is available. Send your inquiries for more information.
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3'-Amino-Modifier C7 CPG 1000
3'-amino-Modifier CPG contains an amino group and is protected by the base-vulnerable Fmoc group, designed to functionalize the 3'-terminal of the target oligonucleotide by introducing a primary amine. Group: Pharmaceutical. Alternative Names: 3'-Amino-Modifier C7 CPG; 3'-Amino-Modifier C7 CPG (1000 ?); 3'-Amino-Modifier C7 CPG 1000?; (2-Dimethoxytrityloxymethyl-6-fluorenylmethoxycarbonylamino-hexane-1-succinoyl)-long chain alkylamino-CPG. Pack Sizes: 1 g. Product ID: B1370-362776. Custom synthesis is available. Send your inquiries for more information.
London
3-Bodipy-propanoic acid
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: BDP FL carboxylic acid;4,4-Difluoro-5,7-dimethyl-3-(2-carboxyethyl)-4-bora-3a,4a-diaza-S-indacene; 7-(2-carboxyethyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; BDP FL acid; BODIPY FL. CAS No. 165599-63-3. Pack Sizes: 100 mg. Product ID: B0245-285195. Molecular formula: C14H15BF2N2O2. Mole weight: 292.093. Custom synthesis is available. Send your inquiries for more information.
London
3'-Cholesterol CPG
3'-Cholesterol CPG 1000 is a highly sought-after phosphoramidite building block, coveted by experts in the field for its impressive versatility and usefulness. Boasting numerous applications within the biomedical industry, its primary function is in the synthesis of oligonucleotides with cholesterol conjugates. Scientists and researchers alike utilize this remarkable product in their study of lipoprotein metabolism, and its effectiveness in the treatment of hypercholesterolemia-associated diseases such as atherosclerosis cannot be overstated. Group: Pharmaceutical. Pack Sizes: 1 g. Product ID: B1370-362784. Custom synthesis is available. Send your inquiries for more information.
London
3'-Cholesteryl-TEG CPG
3'-Cholesteryl-TEG CPG is a bioactive and indispensable chemical used in biomedical research for drug discovery and development. Renowned for its exceptional capacity in oligonucleotide synthesis, where cholesterol conjugation is absolutely indispensable, it holds great promise in the fight against cholesterol-dependent diseases such as atherosclerosis and hypercholesterolemia. Its prowess in the arena is unchallenged and highly sought after. Group: Pharmaceutical. Alternative Names: 3'-Cholesteryl-TEG CPG 1000Å; 1-Dimethoxytrityloxy-3-O-(N-cholesteryl-3-aminopropyl)-triethyleneglycol-glyceryl-2-O-succinoyl-long chain alkylamino-CPG. Pack Sizes: 1 g. Product ID: B1370-376393. Custom synthesis is available. Send your inquiries for more information.
TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement. Group: Pharmaceutical. Alternative Names: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite. CAS No. 325683-96-3. Pack Sizes: 1 g. Product ID: B1370-376748. Molecular formula: C45H50N5O8P. Mole weight: 819.9. Custom synthesis is available. Send your inquiries for more information.
3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite is a highly complex chemical compound utilized in the biomedical industry to fabricate nucleic acid-based drugs that effectively combat a multitude of ailments, including but not limited to cancer, viral infections, and genetic disorders. The intricate nature of the molecule allows for the synthesis of oligonucleotides that specifically target variably expressed genes, culminating in an unparalleled approach towards achieving precision medication. Procuring this compound necessitates a specialized skill set and equipment, and can only be obtained from esteemed chemical outlets. Group: Pharmaceutical. Alternative Names: DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite; TNA-G(O-CONPh2)(N-Ac)CE-Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[2-(acetylamino)-6-[[(diphenylamino)carbonyl]oxy]-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; 2-Acetamido-9-((2R,3R,4S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl diphenylcarbamate. CAS No. 325683-97-4. Pack Sizes: 1 g. Product ID: B1370-376749. Molecular formula: C54H57N8O9P. Mole weight: 993.05. Custom synthesis is available. Send your inquiries for more information.
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3'-PT-Amino-Modifier C6 CPG
3'-PT-Amino-Modifier C6 CPG, a specialized product that plays an essential role in the biomedical industry, facilitates the efficient and specific synthesis of oligonucleotides by serving as a solid support throughout the synthesis procedure. Its exceptional utility in the development of antisense drugs targeting an array of diseases, such as cancer, viral infections, and genetic disorders, underscores its criticality in biomedicine. With its high yield and purity, this product empowers researchers to create custom oligonucleotides, thereby rendering it an indispensable tool in the field of biomedicine. Group: Pharmaceutical. Alternative Names: 3'-PT Amino C6 CPG; N-(6-(O-Dimethoxytrityl)-hexyl)-(2-carboxamide)-phthalimidyl-lcaa-CPG; 3'-PT-Amino-Modifier C6 CPG 1000Å; 3'-PT Amino-Modifier C6 CPG 1000. Pack Sizes: 1 g. Product ID: B1370-376414. Custom synthesis is available. Send your inquiries for more information.
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. CAS No. 1134484-25-5. Pack Sizes: 100 mg. Product ID: B1370-285109. Molecular formula: C18H18BF2N3. Mole weight: 325.16. Custom synthesis is available. Send your inquiries for more information.
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5'-Amino Modifier
MMT-Hexylaminolinker Phosphoramidite is designed for use in automatic synthesizers to functionalize the sequence of the 5'end of the target oligonucleotide. The use of trityl-protected amino-modifiers is recommended when purification is required prior to use. Group: Pharmaceutical. Alternative Names: 6-(4-Monomethoxytrityl)-hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-MMT-C6 Amino Modifier; 5'-Amino C6 Modifier Amidite. CAS No. 114616-27-2. Pack Sizes: 5 g. Product ID: B1370-355080. Molecular formula: C35H48N3O3P. Mole weight: 589.75. Custom synthesis is available. Send your inquiries for more information.
London
5'-DMT-2'-O-TBDMS-rU Phosphoramidite
5'-DMT-2'O-TBDMS-rU Phosphoramidite is a classic 2-OTBDMS phosphoramidite used to incorporate U into synthetic oligonucleotides. Group: Pharmaceutical. Alternative Names: rU Phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DMT-2'-O-TBDMS-rU Phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite; 5'-DMT-2'-O-TBDMS-Uridine Phosphoramidite; DMT-2'-O-TBDMS-U-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-uridine-3'-cyanoethyl Phosphoramidite. CAS No. 118362-03-1. Pack Sizes: 25 g. Product ID: B1370-082186. Molecular formula: C45H61N4O9PSi. Mole weight: 861.04. Custom synthesis is available. Send your inquiries for more information.
London
5'-Hexynyl CE Phosphoramidite
5'-Hexynyl CE Phosphoramidite, an essential reagent in biomedical research for oligonucleotide synthesis, offers versatility in sequencing modification through its alkyne functionality, enabling conjugation with diverse biomolecules. The reagent presents vast potential in critical fields such as gene therapy, drug discovery, and disease diagnosis and management. Its unique characteristics position it as a promising asset in achieving complex nucleotide sequencing, furthering our understanding of genetic health and disease. Group: Pharmaceutical. Alternative Names: 2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite; 5-Hexyn-1-yl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. CAS No. 1048985-37-0. Pack Sizes: 100 mg. Product ID: 1048985-37-0. Molecular formula: C15H27N2O2P. Mole weight: 298.37. Custom synthesis is available. Send your inquiries for more information.
London
5-Methyl-2'-Fluoro-U Phosphoramidite
5-Methyl-2'-Fluoro-U Phosphoramidite, a pivotal compound with paramount significance in the domain of biomedicine, assumes the role of a fundamental constituent within the intricate framework of synthesized nucleic acids. Its exceptional utility lies in its indispensable contribution to the progressive advancement of antisense oligonucleotide development. Notably, this phosphoramidite possesses an intrinsic capacity to effectively combat a myriad of ailments encompassing viral infections and genetic disorders, by selectively targeting specified genes or RNA sequences. Group: Pharmaceutical. Alternative Names: 5-Me-5'-O-DMT-2'-fluoro-2'-Deoxyuridine 3'-CE phosphoramidite; 2'-F T amidite; 2'-Fluoro-dT Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-Fluoro-5MeU-3'-phosphoramidite; DMTr-2'-F-dT-3'-CE-Phosphoramidite; DMT-5-Me-2'-F-dU-CE-Phosphoramidite. CAS No. 182700-06-7. Pack Sizes: 5 g. Product ID: B1370-288524. Molecular formula: C40H48FN4O8P. Mole weight: 762.82. Custom synthesis is available. Send your inquiries for more information.
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluorouridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified phosphoramidite designed for use in the synthesis of stable and efficient RNA and DNA oligonucleotides. Its protective groups and modifications enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in the production of antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications. Group: Pharmaceutical. Alternative Names: 2'-F-dU Phosphoramidite; DMT-2'Fluoro-dU Phosphoramidite; 5'-O-Dimethoxytrityl-2'-fluoro-2'-deoxyuridine 3'-CE phosphoramidite; 2'-Deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-fluorouridine 3-CE phosphoramidite; DMT-2'-Fluoro-dU amidite; 2'-Fluoro-2'-deoxy Uridine CED Phosphoramidite; 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3-CE phosphoramidite; 5'-O-DMT-2'-F-dU 3'-CE phosphoramidite. CAS No. 146954-75-8. Pack Sizes: 5 g. Product ID: B2706-084339. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. Custom synthesis is available. Send your inquiries for more information.
London
5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite
5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite stands as an indispensable entity within the realm of biomedicine, wherein its applications for the synthesis of nucleic acids in investigative capacities hold paramount significance. DNA and RNA oligonucleotides rely on this product as their cornerstone, as it seamlessly integrates 2'-deoxyuridine into nucleic acid sequences with exacting efficiency. Aiding the progression of pharmaceutical innovation, gene therapy, and genetic exploration, it emerges as an invaluable instrument that propels advancements in the remediation of diverse medical afflictions. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 2'-Deoxy-5'-O-DMT-uridine 3'-CE Phosphoramidite; DMT-dU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,2-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine. CAS No. 109389-30-2. Pack Sizes: 10 g. Product ID: B2706-252233. Molecular formula: C39H47N4O8P. Mole weight: 730.8. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-Fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a 5'-dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a 2'-fluoro modification to enhance stability and binding affinity, an N2-isobutyryl group protecting the exocyclic amine of the guanine base, and a cyanoethyl (CE) group on the 3'-phosphoramidite. These modifications make it suitable for synthesizing oligonucleotides with improved resistance to enzymatic degradation and enhanced hybridization properties, which are crucial for applications in research, diagnostics, and therapeutics. Group: Pharmaceutical. Alternative Names: 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite; 2'-F-iBu-G-CEP; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; DMT-2'Fluoro-dG(iBu) Phosphoramidite; 2'-F-dG(iBu) 3'-CE phosphoramidite; DMT-2'-F-dG(iBu)-CE Phosphoramidite; 2'-F-dG(iBu)-CE Phosphoramidite; 2'-Fluoro-N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite. CAS No. 144089-97-4. Pack Sizes: 5 g. Product ID: B2706-291975. Molecular formula: C44H53FN7O8P. Mole weight: 857.91. Custom synthesis is available. Send your inquiries for more information.
London
5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a phosphoramidite reagent used to introduce 2-O-methyl modified U nucleotide into oligonucleotides. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite; 2'-OMe-U-CEP; 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)uridine. CAS No. 110764-79-9. Pack Sizes: 5 g. Product ID: B2706-081651. Molecular formula: C40H49N4O9P. Mole weight: 760.81. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-TBDMS-5-Methyl-Uridine 3'-CE phosphoramidite is a modified phosphoramidite reagent used in oligonucleotide synthesis. This compound features protective groups: a dimethoxytrityl (DMT) group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) group at the 2'-hydroxyl position, and a cyanoethyl (CE) protecting group on the phosphoramidite moiety. These modifications allow for the efficient incorporation of 5-methyluridine into synthetic oligonucleotides, enhancing their stability and binding affinity, which is crucial for applications in genetic research and therapeutic development. Group: Pharmaceutical. Alternative Names: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-uridine-3'-cyanoethyl phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-2-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-thymin-1-yl-beta-D-ribo. CAS No. 159639-78-8. Pack Sizes: 500 mg. Product ID: B1370-291978. Molecular formula: C46H63N4O9PSi. Mole weight: 875.09. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite, a highly versatile and indispensable compound within the biomedical industry, occupies a paramount position in the synthesis of oligonucleotides of immense significance. Blending seamlessly with various applications including gene therapy, nucleic acid-based diagnostics, and drug development, this invaluable marvel propels the progress of medical science. Its inherent ability to modify nucleotide sequences bestows unmatched stability and facilitates target-specific drug conveyance, fostering advancements in the treatment of multifarious diseases, encompassing cancer and genetic disorders. Group: Pharmaceutical. Alternative Names: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-; 1-[2-O-(tert-Butyldimethylsilyl)-3-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-beta-L-ribofuranosyl]uracil; DMT-2'-O-TBDMS-L-rU Phosphoramidite; L-RNA 2'-OTBS U amidite; 5'-O-DMT-2'-O-TBDMS-L-U 3'-CE phosphoramidite. CAS No. 144490-31-3. Pack Sizes: 1 g. Product ID: B1370-291976. Molecular formula: C45H61N4O9PSi. Mole weight: 861.06. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite, a sophisticated compound integral to the production of custom oligonucleotides, showcases remarkable versatility. It serves as a phosphoramidite foundation during solid-phase DNA synthesis, facilitating the integration of guanosine modifications. By harnessing this product, nucleic acid researchers can probe gene expression or delve into the impact of guanosine alterations on ailments such as cancer. Group: Pharmaceutical. Alternative Names: DMT-2'-O-TBDMS-L-rG(ibu) Phosphoramidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; L-rG(ibu) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. CAS No. 679809-76-8. Pack Sizes: 1 g. Product ID: B1370-291987. Molecular formula: C50H68N7O9PSi. Mole weight: 970.19. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite, a remarkable substance within the biomedical field, holds immense significance. Its application in the synthesis of altered oligonucleotides for therapeutic intentions is widespread. Through the specific manipulation and addressing of genetic material, particularly RNA, it exhibits a pivotal role in combating diverse ailments. Boasting an exceptional composition, this product possesses the power to revolutionize precision medicine and propel the progression of targeted therapies. Group: Pharmaceutical. Alternative Names: Acetamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-; DMT-2'-O-TBDMS-L-rC(Ac) Phosphoramidite. CAS No. 237060-94-5. Pack Sizes: 1 g. Product ID: B1370-291982. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite is a crucial reagent used in the synthesis of oligonucleotides for biomedical research. It enables the efficient introduction of N6-benzoyl-L-Adenosine residues into the oligonucleotide chain, thus allowing the study of adenosine-modified nucleic acids. This product finds applications in drug discovery, gene therapy, and understanding diseases related to adenosine signaling pathways. Group: Pharmaceutical. Alternative Names: Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-9H-purin-6-yl]-; N-Benzoyl-9-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-9H-purin-6-amine; DMT-2'-O-TBDMS-L-rA(Bz) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-A(Bz)-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-adenosine-3'-cyanoethyl Phosphoramidite. CAS No. 1803193-36-3. Pack Sizes: 1 g. Product ID: B1370-291981. Molecular formula: C53H66N7O8PSi. Mole weight: 988.21. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used for incorporating ribo-G into synthetic oligonucleotides. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; iBu-rG CE phosphoramidite; DMT-2'-O-TBDMS-rG(iBu) Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine; 5'-O-DMT-2'-O-TBDMS-N2-Isobutyryl-Guanosine-CE Phosphoramidite; 2'-TBDMS-ibu-G-CE-Phosphoramidite; DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine-3'-cyanoethyl Phosphoramidite. CAS No. 147201-04-5. Pack Sizes: 25 g. Product ID: B1370-084362. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Group: Pharmaceutical. Alternative Names: 5-F-dU Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. CAS No. 142246-63-7. Pack Sizes: 250 mg. Product ID: B2706-049657. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite, an indispensable constituent in the biomedical sector, finds extensive application in the synthesis of oligonucleotides for diagnostics and research studies. Its pivotal role encompasses the progress of nucleic acid-centered therapies and drug exploration, with a primary focus on combatting a wide range of diseases, encompassing cancer, genetic disorders, and viral infections. Group: Pharmaceutical. Alternative Names: 5'-O-DMT-N2-(dimethylamino)-2'-Deoxy Guanosine Phosphoramidite; DMF-dG CEP; 5'-Dimethoxytrityl-N-dimethylformamidine-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dmf-dG-CE Phosphoramidite; 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-N-[(dimethylamino)?methylene]?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]. CAS No. 330628-04-1. Pack Sizes: 100 g. Product ID: B2706-231724. Molecular formula: C43H53N8O7P. Mole weight: 824.93. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine 3'-CE phosphoramidite is a pivotal compound employed in oligonucleotide research within the biomedical sector, emerging as an instrumental factor for nucleic acid modification, labeling and analysis. Group: Pharmaceutical. Alternative Names: dG(iBu) CEP; 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 93183-15-4. Pack Sizes: 100 g. Product ID: B1370-100728. Molecular formula: C44H54N7O8P. Mole weight: 839.92. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA. Group: Pharmaceutical. Alternative Names: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O-(2-methoxyethyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-(2-methoxyethyl)guanosine. CAS No. 251647-55-9. Pack Sizes: 1 g. Product ID: B2706-306342. Molecular formula: C47H60N7O10P. Mole weight: 913.99. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite is used to incorporate methyl-C modified with 2'-O-methoxyethyl into oligonucleotides, which is useful for anti-sense RNA. Group: Pharmaceutical. Alternative Names: N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite; 2'-O-MOE-N4-Bz-5-Me-C Phosphoramidite; 5-Me-DMT-2'-O-MOE-C(Bz)-CEP; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)-5-methyl-3,4-dihydrocytidine; 5'-O-DMT-2'-O-MOE-MeC(Bz) 3'-CE phosphoramidite. CAS No. 163759-94-2. Pack Sizes: 1 g. Product ID: B2706-155124. Molecular formula: C50H60N5O10P. Mole weight: 922.01. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology. Group: Pharmaceutical. Alternative Names: N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite; dA(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-adenosine 3'-[2-cyanoethyl N,?N-Bis(1-methylethyl)?phosphoramidite]; DMT-dA(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. CAS No. 98796-53-3. Pack Sizes: 5 g. Product ID: B2706-101370. Molecular formula: C47H52N7O7P. Mole weight: 857.93. Custom synthesis is available. Send your inquiries for more information.
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5'-O-DMTr-2'-OMeU-methylphosphonamidite
5'-O-DMTr-2'-OMeU-methylphosphonamidite is an indispensable recompound widely employed in the field of compound, exhibiting immense significance in the research and development of altered oligonucleotides meticulously crafted for gene therapy and medicinal chemistry. Moreover, it assumes a pivotal role in the research and development of antisense oligonucleotides explicitly engineered to combat genetic disorders, infectious ailments and select malignancies. Group: Pharmaceutical. Alternative Names: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[P-methyl-N,N-bis(1-methylethyl)phosphonamidite]; 5'-O-DMTr-2'-O-methyluridine-3'-O-(P-methyl-N,N-diisopropylamino)phosphonamidite; 2'-OMe U Me-amidite; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((diisopropylamino)(methyl)phosphaneyl)oxy)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-2'-OMe-U-3'-O-[P-methyl-(N,N-diisopropyl)]-Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-OMe-uridine-3'-O-[P-methyl-(N,N-diisopropyl)]-Phosphoramidite; 2'-O-Methyl Uridine p-methyl phosphonamidite. CAS No. 191786-64-8. Pack Sizes: 10 mg. Product ID: B1370-158352. Molecular formula: C38H48N3O8P. Mole weight: 705.78. Custom synthesis is available. Send your inquiries for more information.
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5'-O-DMT-thymidine 3'-CE phosphoramidite
5'-O-DMT-thymidine 3'-CE phosphoramidite is an immensely critical compound employed in the solid-phase synthesis of oligonucleotides, the building blocks of DNA. The chemical is a phosphoramidite derivative of thymidine, which dutifully incorporates into the growing strand of DNA during synthesis, and crucially, in turn, dictates the eventual structure of the resultant chemical entity. As the leading-edge compound known to have tremendous potential in treating an array of viral infections and genetic diseases, this compound has opened new doors of discovery that were previously deemed unattainable. Group: Pharmaceutical. Alternative Names: dT CEP; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 98796-51-1. Pack Sizes: 100 g. Product ID: B2706-383230. Molecular formula: C40H49N4O8P. Mole weight: 744.83. Custom synthesis is available. Send your inquiries for more information.
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6-FAM-DMT-phosphoramidite
6-FAM-DMT Phosphoramidite is a phosphoramidite derivative used to introduce 6-carboxyfluorescein (6-FAM) into oligonucleotides during solid-phase synthesis. It includes a 6-FAM fluorophore and a dimethoxytrityl (DMT) protecting group, which facilitates efficient incorporation and subsequent deprotection during synthesis. This reagent enables the production of fluorescently labeled oligonucleotides for applications such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays. Group: Pharmaceutical. Alternative Names: 6-Fluorescein Phosphoramidite; 2-Dimethoxytrityloxymethyl-6-(3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-6-Fluorescein phosphoramidite (with DMT); Propanoic acid, 2,2-dimethyl-, 6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; DMT-6-FAM phosphoramidite. CAS No. 316121-60-5. Pack Sizes: 250 mg. Product ID: B1370-070723. Molecular formula: C68H78N3O13P. Mole weight: 1176.33. Custom synthesis is available. Send your inquiries for more information.
London
6-Hexachloro-Fluorescein Phosphoramidite
6-Hexachloro-Fluorescein Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Group: Pharmaceutical. Alternative Names: HEX phosphoramidite, 6-isomer; DyLight HEX CEP; 6-(4,7,2',4',5',7'-Hexachloro-3',6'-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[10-[Bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); Hex-C6-amidite. CAS No. 1360547-55-2. Pack Sizes: 1 g. Product ID: B2708-060541. Molecular formula: C46H52N3O10Cl6P. Mole weight: 1050.61. Custom synthesis is available. Send your inquiries for more information.
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7-deaza-8-aza-dA-CE Phosphoramidite
7-deaza-8-aza-dA-CE Phosphoramidite, a molecular component utilized in DNA and RNA synthesis, has garnered attention for its capacity to succeed in the development of oligonucleotides for research and medical applications; particularly in the pursuit to treat genetic disorders and viral infections. This distinguished structure is liable for reinforcing binding capability and stability, and hence, facilitates successful therapeutic outcomes. Group: Pharmaceutical. Alternative Names: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-aza-7-deaza-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2-(Dimethylaminomethylidene)amino-9-(2-deoxy-b-D-ribofuranosyl)purine 3'-CE phosphoramidite. Pack Sizes: 50 mg. Product ID: B1370-376453. Molecular formula: C43H53N8O6P. Mole weight: 808.91. Custom synthesis is available. Send your inquiries for more information.
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8(4'-bromophenyl)-1,3,5,7-tetramethyl-BODIPY
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 8-(4-Bromophenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene. CAS No. 850534-66-6. Pack Sizes: 10 mg. Product ID: B2708-285104. Molecular formula: C19H18BBrF2N2. Mole weight: 403.077. Custom synthesis is available. Send your inquiries for more information.
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8-Azanebularine CE-Phosphoramidite
DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite is a chemical compound used in oligonucleotide synthesis. It protects the 5'-hydroxyl group with a DMTr group and stabilizes the ribose sugar with a 2'-O-TBDMS modification. Additionally, it incorporates 8-azanebularine as a modified nucleoside. The 3'-CE phosphoramidite facilitates nucleotide addition during synthesis. This compound allows for the controlled synthesis of oligonucleotides with specific modifications, important for various applications in molecular biology and biotechnology. Group: Pharmaceutical. Alternative Names: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite. CAS No. 771494-03-2. Pack Sizes: 50 mg. Product ID: B1370-087581. Molecular formula: C45H60N7O7PSi. Mole weight: 870.08. Custom synthesis is available. Send your inquiries for more information.
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A(Ac)-TOM-CE Phosphoramidite
2'-O-TOM-A(Ac) Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It features a 2'-O-TOM (2'-O-tomc) modification attached to an adenosine (A) nucleotide, along with an acetyl (Ac) group. This modification enhances stability and protects against nuclease degradation. It is often employed in applications such as RNA interference, gene expression modulation, and therapeutic RNA-based treatments. The synthesis of RNA using monomers containing the 2'-O-Triisopropylsilyloxymethyl (TOM) group (TOM-Protecting-Group) has very high coupling efficiency along with fast, simple deprotection. Group: Pharmaceutical. Alternative Names: 5'-Dimethoxytrityl-N-acetyl-Adenosine, 2'-O-triisopropylsilyloxymethyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Acetyl-2'-O-[(triisopropylsilyloxy)methyl]-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)adenosine; Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methyleth. CAS No. 253586-13-9. Pack Sizes: 1mg;1g;10g. Product ID: 253586-13-9. Molecular formula: C52H72N7O9PSi. Mole weight: 998.23. Custom synthesis is available. Send your inquiries for more information.
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Abasic II phosphoramidite
Abasic II Phosphoramidite, a highly valuable chemical compound, plays a pivotal role in oligonucleotide synthesis, particularly in the context of medicinal applications, as it affords the unique ability to generate modified nucleic acids that combat cancer and genetic disorders. This innovative compound is exceedingly crucial in the biomedical sphere as it transforms the course of advanced therapeutics. Group: Pharmaceutical. Alternative Names: 5-O-Dimethoxytrityl-1-O-tert-butyldimethylsilyl-2-deoxyribose-3-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; α-D-erythro-Pentofuranose, 5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-1-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. CAS No. 1835233-43-6. Pack Sizes: 1mg;1g;10g. Product ID: 1835233-43-6. Molecular formula: C41H59N2O7PSi. Mole weight: 750.98. Custom synthesis is available. Send your inquiries for more information.
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Ac-rC Phosphoramidite
Ac-rC Phosphoramidite is a commonly used protected 2-OTBDMS phosphoramidite for incorporating cytidine nucleotides into synthetic oligonucleotides. Group: Pharmaceutical. Alternative Names: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine 3'-CE phosphoramiditee; 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl-2'-O-t-butyldimethylsilylcytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite; DMT-2'-O-TBDMS-rC(ac) Phosphoramidite; 2'-TBDMS-Ac-rC-CE-Phosphoramidite; 5'-DMT-2'-O-TBDMS-N4-Acetyl-Cytidine Phosphoramidite. CAS No. 121058-88-6. Pack Sizes: 25 g. Product ID: B1370-082410. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11. Custom synthesis is available. Send your inquiries for more information.
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Alkyne-Modifier Serinol Phosphoramidite
Alkyne-Modifier Serinol Phosphoramidite is a potent chemical reagent that pervasively aids in the synthesis of oligonucleotides for biomedical research purposes. Its proficiency lies in the assortment, stability, solubility enhancement and augmented bioavailability of DNA and RNA modification. Not only that, it proficiently gets the job done in developing gene therapies with targeted drug delivery systems for treating ailments like cancer, viral infections, and genetic disorders. Group: Pharmaceutical. Alternative Names: 3-Dimethoxytrityloxy-2-(3-(5-hexynamido)propanamido)propyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl ester; 3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite. CAS No. 2084118-98-7. Pack Sizes: 250 mg. Product ID: B1370-376461. Molecular formula: C42H55N4O7P. Mole weight: 758.88. Custom synthesis is available. Send your inquiries for more information.
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BDY FL, SE
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 3-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 7-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Propionic Acid, Succinimidyl Ester; BDP FL NHS ester. CAS No. 146616-66-2. Pack Sizes: 50 mg. Product ID: B0245-118888. Molecular formula: C18H18BF2N3O4. Mole weight: 389.166. Custom synthesis is available. Send your inquiries for more information.
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C3-Spacer-CEP
C3-Spacer-CEP is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required. Group: Pharmaceutical. Alternative Names: 3-(4,4'-Dimethoxytrityloxy)propyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Spacer Phosphoramidite C3; 3-(Bis(4-methoxyphenyl)phenylmethoxy)propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-(bis(4-methoxyphenyl)phenylmethoxy)propyl 2-cyanoethyl ester; Spacer-C3 CEP; Spacer-C3 Phosphoramidite; 3-(Bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropyl phosphoramidite. CAS No. 110894-23-0. Pack Sizes: 1 g. Product ID: B2706-331216. Molecular formula: C33H43N2O5P. Mole weight: 578.68. Custom synthesis is available. Send your inquiries for more information.
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Chemical Phosphorylation Reagent II
N,N-diisopropylphosphoramidite, a catalytic compound, is an essential building block for oligonucleotide synthesis used in various therapeutic domains such as antisense therapy, siRNA, and gene editing. This efficient and highly pure chemical ensures the production of top-quality therapeutic oligonucleotides. Group: Pharmaceutical. Alternative Names: O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol; CP?; CPRII; 2-[(4,4'-Dimethoxytrityloxy)methyl]-2-[[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]methyl]malonic acid diethyl ester; 3-(4,4'-dimethoxytrityloxy)-2,2-dicarboxyethyl]propyl(2-cyanoethyl)(N, N-diisopropyl)phosphoramidite; (2-Cyanoethyl) (2,2-bis(ethoxycarbonyl)-3-(4,4'-dimethoxytrityloxy)propyl-1) N,N-diisopropylphosphoramidite. CAS No. 171285-25-9. Pack Sizes: 1 g. Product ID: B1370-376742. Molecular formula: C39H51N2O9P. Mole weight: 722.8. Custom synthesis is available. Send your inquiries for more information.
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Cy5-NHS ester tetrafluoroborate
Cy5-NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Group: Pharmaceutical. Alternative Names: Cyanine5 NHS ester (tetrafluoroborate);Cyanine5 NHS ester tetrafluoroborate. CAS No. 1263093-76-0. Pack Sizes: 10 mg. Product ID: B1370-409784. Molecular formula: C36H42BF4N3O4. Mole weight: 667.55. Custom synthesis is available. Send your inquiries for more information.
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CY7-SE triethylamine
CY7-SE Triethylamine is a fluorescence labeling agent (Ex = 700-770 nm, Em = 790 nm) used for labeling proteins, peptides, antibodies, and oligonucleotides. Group: Pharmaceutical. Alternative Names: Cy7-NHS ester triethylamine; 3H-Indolium, 2-[7-[1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-, inner salt, triethylamine; CY 7 NHS ester triethylamine; Cy 7.29.OSu triethylamine; N-Hydroxysuccinimidyl Cy7 triethylamine. Pack Sizes: 20 mg. Product ID: B1370-447393. Molecular formula: C45H60N4O10S2. Mole weight: 881.11. Custom synthesis is available. Send your inquiries for more information.
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Cyanine 3 Phosphoramidite
Cyanine 3 Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Group: Pharmaceutical. Alternative Names: 2-[3-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium; 2-[3-[1-[3-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[3-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propenyl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-; 2-(3-(1-(3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propyl)-3,3-dimethylindolin-2-ylidene)prop-1-en-1-yl)-1-(3-((4-methoxyphenyl)diphenylmethoxy)propyl)-3,3-dimethyl-3H-indol-1-ium. CAS No. 718594-66-2. Pack Sizes: 500 mg. Product ID: B2708-099490. Molecular formula: C58H70N4O4P. Mole weight: 918.17. Custom synthesis is available. Send your inquiries for more information.
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Cyanine5.5 NHS ester
Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester. Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments. Group: Pharmaceutical. CAS No. 1469277-96-0. Pack Sizes: 5 mg. Product ID: R01-0021. Molecular formula: C44H46N3ClO4. Mole weight: 716.32. Custom synthesis is available. Send your inquiries for more information.
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Cyanine 5 Phosphoramidite
Cyanine 5 Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Group: Pharmaceutical. Alternative Names: 2-[5-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[5-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-; 2-[5-[1-[3-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[5-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadienyl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-. CAS No. 351186-76-0. Pack Sizes: 250 mg. Product ID: B2708-108359. Molecular formula: C60H72N4O4P. Mole weight: 944.21. Custom synthesis is available. Send your inquiries for more information. Categories: Cyanine5 Phosphoramidite.
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dSpacer-CEP
dSpacer is used to introduce stable abasic sites in oligonucleotides. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R,3S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. CAS No. 129821-76-7. Pack Sizes: 100 mg. Product ID: B2705-072846. Molecular formula: C35H45N2O6P. Mole weight: 620.71. Custom synthesis is available. Send your inquiries for more information.
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DyLight 5 CEP
DyLight 5 CEP is a fluorescent dye used for oligonucleotide labeling. Group: Pharmaceutical. Alternative Names: Cy5 MMTr CE Phosphoramidite; 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropylphosphoramidityl]propyl]-3,3,3',3'-tetramethylindodicarbocyanine chloride; Cyanine 5 Phosphoramidite. CAS No. 182873-67-2. Pack Sizes: 250 mg. Product ID: B1370-359488. Molecular formula: C60H72CIN4O4P. Mole weight: 979.68. Custom synthesis is available. Send your inquiries for more information.
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Fomivirsen
Fomivirsen is an antisense oligonucleotide, a synthetic 21 member oligonucleotide with phosphorothioate linkages (which are resistant to degradation by nucleases). Group: Pharmaceutical. Alternative Names: ISIS-2922 free base. CAS No. 144245-52-3. Pack Sizes: 5 mg. Product ID: B1370-272861. Molecular formula: C204H263N63O114P20S20. Mole weight: 6682.4. Custom synthesis is available. Send your inquiries for more information.
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GalNAc-INF7
GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Group: Pharmaceutical. Alternative Names: GalNAc-CGLFEAIEGFIENGWEGMIDGWYG. Pack Sizes: 5 mg. Product ID: B1370-410022. Molecular formula: C189H303N39O70S2. Mole weight: 4305.78. Custom synthesis is available. Send your inquiries for more information.
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GalNAc trimer-Cy5.5
GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. Cy5.5 (Cyanine-5.5) is a cyanine dye. Group: Pharmaceutical. Alternative Names: GalNAc trimer-Cyanine5.5. Pack Sizes: 5 mg. Product ID: B1370-410021. Molecular formula: C112H172N13O33. Mole weight: 2228.63. Custom synthesis is available. Send your inquiries for more information.
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hsa-miR-146a-5p antagomir
hsa-miR-146a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo. Group: Pharmaceutical. Pack Sizes: 5 nmol. Product ID: B1370-449811. Mole weight: 7311.74. Custom synthesis is available. Send your inquiries for more information.
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hsa-miR-146a-5p Inhibitor
hsa-miR-146a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. hsa-miR-146a-5p inhibitors have full-length nucleotide 2'-methoxy modification. They strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Group: Pharmaceutical. Pack Sizes: 5 nmol. Product ID: B1370-449809. Mole weight: 6592.37. Custom synthesis is available. Send your inquiries for more information.
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Imetelstat
Imetelstat is a telomerase inhibitor, also a synthetic lipid-conjugated, 13-mer oligonucleotide N3' P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the template region of telomerase RNA (hTR), imetelstat acts as a competitive enzyme inhibitor that binds and blocks the active site of the enzyme (a "telomerase template antagonist"), a mechanism of action which differs from that for the antisense oligonucleotide-mediated inhibition of telomerase activity through telomerase mRNA binding. Inhibition of telomerase activity in tumor cells by imetelstat results in telomere shortening, which leads to cell cycle arrest or apoptosis. Group: Pharmaceutical. Alternative Names: Rytelo; GRN163L. CAS No. 868169-64-6. Pack Sizes: 1 mg. Product ID: B1370-462541. Custom synthesis is available. Send your inquiries for more information.
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Inotersen sodium
Inotersen sodium, a 2'-O-methoxyethyl-modified antisense oligonucleotide, inhibits the production of transthyretin (TTR) protein by targeting the TTR RNA transcript and reduces the levels of the TTR transcript. Group: Pharmaceutical. Alternative Names: ISIS-420915 sodium; ISIS 420915 sodium; ISIS420915 sodium. CAS No. 1432726-13-0. Pack Sizes: 5 mg. Product ID: B1370-426343. Custom synthesis is available. Send your inquiries for more information.
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meso-CH2Br-BODIPY
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: BODIPY 493/503 Methyl Bromide; 8-Bromomethyl-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-S-indacene. CAS No. 216434-81-0. Pack Sizes: 10 mg. Product ID: B1370-102399. Molecular formula: C14H16BBrF2N2. Mole weight: 341.01. Custom synthesis is available. Send your inquiries for more information.
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