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| Product | Description | |
|---|---|---|
| Oclacitinib maleate | Oclacitinib maleate was the first selective Janus kinase (JAK) inhibitor to be developed for dogs. Oclacitinib is most potent at inhibiting JAK1 (IC50=10 nM). Group: Pharmaceutical. Alternative Names: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-, (2Z)-2-butenedioate (1:x); Apoquel; Oclacitinib maleate (1:x); PF 03394197-11; trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanemethanesulfonamide maleate (1:x); N-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide maleate. CAS No. 1208319-27-0. Pack Sizes: 10 g. Product ID: B1370-007675. Molecular formula: C15H23N5O2S.xC4H4O4. Mole weight: 337.44 (free base). Custom synthesis is available. Send your inquiries for more information. |  London |
| Oclacitinib monomaleate | Oclacitinib, also called as PF-03394197, is a novel inhibitor of JAK family members (IC50 = 10 - 99 nM) and JAK1-dependent cytokines involved in allergy, inflammation, and pruritus (IC50 = 36 - 249 nM), without affecting a panel of 38 non-JAK kinases. It could reduce pruritus and associated inflammatory skin lesions in dogs with AD. Group: Pharmaceutical. Alternative Names: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-, (2Z)-2-butenedioate (1:1); trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanemethanesulfonamide maleate (1:1); N-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide monomaleate. CAS No. 1640292-55-2. Pack Sizes: 50 mg. Product ID: B2693-008142. Molecular formula: C15H23N5O2S.C4H4O4. Mole weight: 453.51. Custom synthesis is available. Send your inquiries for more information. | London |
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