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| Product | Description | |
|---|---|---|
| Obatoclax mesylate | Obatoclax mesylate is the mesylate salt of obatoclax, a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl-2 protein family, preventing the binding of these anti-apoptotic proteins to the pro-apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl-2-overexpressing cells. The Bcl-2 family of proteins (bcl-2, bcl-xl, bcl-w, and Mcl-1) are overexpressed in a wide variety of cancers, including those of the lymphatic system, breast, lung, prostate, and colon. Group: Pharmaceutical. Alternative Names: (2E)-2-[(5Z)-5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-4-methoxypyrrol-2-ylidene]indole methanesulfonic acid. CAS No. 803712-79-0. Pack Sizes: 500 mg. Product ID: B0084-135253. Molecular formula: C20H19N3O.CH4O3S. Mole weight: 413.492. Custom synthesis is available. Send your inquiries for more information. |  London |
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