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Nutlin-3a Nutlin-3a is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin-3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein. Group: Pharmaceutical. Alternative Names: rebemadlin; (-)-Nutlin-3; Nutlin-3a chiral. CAS No. 675576-98-4. Pack Sizes: 10 mg. Product ID: B0084-425358. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.5. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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