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| Product | Description | |
|---|---|---|
| β-Nicotinamide Adenine Dinucleotide | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of several enzymes, such as poly(ADP)-ribose polymerases and cADP-ribose synthases. NAD+ is commonly used as an oxidizing agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt; Nadide; Coenzyme I; Beta-NAD; Diphosphopyridine nucleotide; NAD+; Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt; Adenine-nicotinamide dinucleotide; CO-I; Codehydrase I; Codehydrogenase I; Cozymase I; DPN; Enzopride; NAD; Nicotinamide-adenine dinucleotide; NSC 20272; Oxidized diphosphopyridine nucleotide; β-Diphosphopyridine nucleotide; β-NAD; β-NAD+. CAS No. 53-84-9. Pack Sizes: 10 g. Product ID: B0084-094034. Molecular formula: C21H27N7O14P2. Mole weight: 663.43. Custom synthesis is available. Send your inquiries for more information. |  London |
| beta-Nicotinamide adenine dinucleotide phosphate | NADP zwitterion is a NADP. It has a role as a fundamental metabolite. It is a conjugate base of a NADP(+). A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). Group: Pharmaceutical. Alternative Names: beta-NADP; NADP; TPN; Triphosphopyridine nucleotide; coenzyme II; Codehydrogenase II; Nadide phosphate. CAS No. 53-59-8. Pack Sizes: 50 g. Product ID: B1370-093984. Molecular formula: C21H28N7O17P3. Mole weight: 743.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Polydeoxyribonucleotide | Polydeoxyribonucleotide (PDRN) is a mixture of deoxyribonucleic acids that is derived from fish sperm DNA, specifically salmon, and has a high degree of similarity with human DNA, around 98%. It is known for its multiple biological activities including anti-inflammatory properties, tissue repair, wound healing promotion, stimulation of angiogenesis, anti-melanogenesis, and anti-aging effects. PDRN is widely researched in the field of dermatology and is used in various cosmetic and medical applications for its ability to promote skin health and regeneration. PDRN promotes cell proliferation and collagen synthesis, which helps reduce wrinkles, improve skin elasticity, and repair damaged skin. It is commonly incorporated into creams, serums, and masks, and can be delivered through micro-needling to enhance absorption. Group: Pharmaceutical. Alternative Names: PDRN/polydeoxyribonucleotide; Polydeoxyribonucleotides; Deoxyribonucleotides, polydeoxyribonucleotides; Nucleotides, poly-, deoxyribo-; Nucleotides, polydeoxyribo-; Polynucleotides, polydeoxyribonucleotides; Condrotide; Deoxypolynucleotides; Deoxyribopolynucleotides. CAS No. 1520839-56-8. Pack Sizes: 10 g. Product ID: B1370-092583. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,3,5,7-Tetramethyl-8-(C3-COOH)4,4-difluoro-4-bora-3a,4a-diaza-s-indacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 4-(4,4-Difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-yl)-butyric Acid. CAS No. 878674-84-1. Pack Sizes: 10 mg. Product ID: B0245-044224. Molecular formula: C17H21BF2N2O2. Mole weight: 334.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 4,4-Difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene. CAS No. 194235-40-0. Pack Sizes: 1 g. Product ID: B1370-285100. Molecular formula: C19H19BF2N2. Mole weight: 324.18. Custom synthesis is available. Send your inquiries for more information. | London |
| (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Group: Pharmaceutical. Alternative Names: (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane; (7S)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine. CAS No. 866783-13-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3532. Molecular formula: C12H18ClNO2. Mole weight: 243.73. Custom synthesis is available. Send your inquiries for more information. | London |
| 2',3'-cGAMP | 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Group: Pharmaceutical. Alternative Names: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5'). CAS No. 1441190-66-4. Pack Sizes: 1 mg. Product ID: B1370-006099. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,6-Diiodo-1,3,5,7,8-pentaethyl-BODIPY | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. CAS No. 1031443-55-6. Pack Sizes: 50 mg. Product ID: B1370-285124. Molecular formula: C14H15BF2I2N2. Mole weight: 513.9. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,6-Diiodo-1,3,5,7-tetramethyl-8-phenyl-4,4-difluoroboradiazasindacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 5,5-Difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 1083009-44-2. Pack Sizes: 10 mg. Product ID: B2708-285125. Molecular formula: C19H17BF2I2N2. Mole weight: 575.974. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Aminoadenosine-5'-Triphosphate 100mM Sodium Solution | 2-Aminoadenosine-5'-Triphosphate, a versatile compound, finds extensive applications in enzymology and biotechnology as a substrate for kinases, ATPases, and nucleotide pyrophosphatases. Additionally, it is noteworthy for its ability to stimulate bone resorption activity in separated osteoclasts, therefore facilitating the study of bone metabolism and related diseases like osteoporosis and osteopenia. Group: Pharmaceutical. Alternative Names: 2-Amino-adenosine-5'-triphosphate; 2-NH2-ATP; 2-Amino-ATP; 2,6-Diaminopurine-ribose-5'-Triphosphate; DAP-rTP; 2-Aminoadenosine 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-triphosphate; 2,6-Diaminopurine ribonucleoside triphosphate; 2,6-Diaminopurine riboside 5'-triphosphate; 2,6-Diaminopurine riboside triphosphate; 2,6-Diaminopurineribosyl-5'-triphosphate. CAS No. 18549-34-3. Pack Sizes: 1 mL. Product ID: B1370-362752. Molecular formula: C10H17N6O13P3. Mole weight: 522.2. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxycytidine 3'-monophosphate ammonium salt | 2'-Deoxycytidine 3'-monophosphate ammonium salt is a nucleotide-like compound that is extensively employed in scientific research, especially in the disciplines of DNA sequencing and synthesis. Furthermore, it serves as an essential ingredient for various phosphatases and kinases. With its unique properties, it has the potential to combat a variety of viral infections and cancers, thus opening up new avenues for therapeutic interventions. Group: Pharmaceutical. Alternative Names: 2'-Deoxycytidine-3'-monophosphate tetraammonium salt; (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate, ammonia salt; 2'-Deoxy-3'-cytidylic acid ammoniate (1:1); 2'-Desoxycytidine 3'-(dihydrogen phosphate) ammonium salt (1:1). CAS No. 102783-50-6. Pack Sizes: 20 mg. Product ID: B2001-297040. Molecular formula: C9H17N4O7P. Mole weight: 324.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxyinosine-5'-triphosphate sodium salt | 2'-Deoxyinosine-5'-triphosphate sodium salt, renowned for its multifarious applications in enzymatic labeling, sequencing, and mutagenesis, is a popular nucleotide analogue adopted in the biomedical industry. Apart from its widespread usage in these areas, it has also shown promising outcomes in treating viral infections and cancer. Group: Pharmaceutical. Alternative Names: dITP.3Na; Inosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-, trisodium salt; 9H-Purin-6-ol, 9-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-erythro-pentofuranosyl]-, sodium salt (1:3); sodium ((2R,3S,5R)-3-hydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl hydrogen triphosphate. CAS No. 95648-77-4. Pack Sizes: 1 mL. Product ID: B2706-195580. Molecular formula: C10H12N4Na3O13P3. Mole weight: 558.11. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxy-N4-methylcytidine | 2'-Deoxy-N-methyl-cytidine is a nucleotide derivative used as an analytical reagent. Group: Pharmaceutical. Alternative Names: 2'-Deoxy-N-methyl-cytidine; N4-Methyldeoxycytidine; N(3)-Methyl-2'-deoxycytidine; N4-Methyl-2'-deoxycytidine; N-methyldeoxycytidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(methylamino)pyrimidin-2(1H)-one. CAS No. 22882-02-6. Pack Sizes: 25 mg. Product ID: B2706-338157. Molecular formula: C10H15N3O4. Mole weight: 241.24. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-Deoxy-N4-methylcytidine 5'-triphosphate sodium | 2'-Deoxy-N4-methylcytidine 5'-triphosphate is a significant compound utilized in the field of compound, holds great importance for DNA research and development. This nucleotide analogue serving as an indispensable resource for delving into the intricate processes of DNA methylation and epigenetic alterations. Group: Pharmaceutical. Alternative Names: N(4)-Methyl-2'-deoxycytidine 5'-triphosphate sodium; N4-Methyl-dCTP sodium. Pack Sizes: 1 mL. Product ID: B1370-458998. Molecular formula: C10H15N3Na3O13P3. Mole weight: 547.13. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-O-Methyluridine-5'-triphosphate 100mM Sodium Solution | 2'-O-Methyluridine-5'-triphosphate is a nucleotide analog commonly used in biochemistry research. It can be used as a substrate for RNA polymerases or as a terminoligical ATP analog for use in RNA synthesis reactions. Its effectiveness as an antiviral and antitumor agent is also being investigated. Group: Pharmaceutical. Alternative Names: 2'-methoxy-UTP; 2'-O-Methyluridine 5'-triphosphoric acid; uridine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-; 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Uridine; 2'-O-Methyluridine 5'-(tetrahydrogen triphosphate); 2'-O-Me-UTP; 2'-OMe-UTP. CAS No. 143028-99-3. Pack Sizes: 1 mL. Product ID: B1370-376840. Molecular formula: C10H17N2O15P3. Mole weight: 498.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Group: Pharmaceutical. Alternative Names: 3-(3-chloropropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one; 3-(3-chloropropyl)-7,8-dimethoxy-2,3-dihydro-1H-3-benzazepin-2-one; 3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one. CAS No. 85175-59-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3534. Molecular formula: C15H18ClNO3. Mole weight: 295.76. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Bodipy-propanoic acid | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: BDP FL carboxylic acid;4,4-Difluoro-5,7-dimethyl-3-(2-carboxyethyl)-4-bora-3a,4a-diaza-S-indacene; 7-(2-carboxyethyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; BDP FL acid; BODIPY FL. CAS No. 165599-63-3. Pack Sizes: 100 mg. Product ID: B0245-285195. Molecular formula: C14H15BF2N2O2. Mole weight: 292.093. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-O-Amino-2'-deoxyadenosine 5'-triphosphate | 3'-O-Amino-2'-deoxyadenosine 5'-triphosphate is a crucial nucleotide derivative widely utilized in the field of biomedicine. It plays a vital role in various biochemical assays and experiments, particularly in the study of DNA replication, repair, and modification processes. Due to its unique molecular structure, it is frequently employed in research related to drug development, DNA sequencing, and targeted therapies for diseases such as cancer and genetic disorders. Group: Pharmaceutical. Alternative Names: 3'-ONH2-dATP Sodium Salt; (((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-(aminooxy)tetrahydrofuran-2-yl)methyl)triphosphoric acid. CAS No. 1220515-87-6. Pack Sizes: 1 mL. Product ID: B1370-337960. Molecular formula: C10H17N6O12P3. Mole weight: 506.2. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite | 3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite is a modified nucleotide used in the synthesis of Threose Nucleic Acid (TNA) molecules for biomedical research. TNA is a promising alternative to DNA and RNA for gene and drug delivery due to its chemical stability and resistance to nuclease degradation. This specific phosphoramidite derivative incorporates a benzoyl-adenosine moiety, making it ideal for designing TNA-based drugs for the treatment of viral infections, inflammatory diseases, and cancer. Group: Pharmaceutical. Alternative Names: DMTr-TNA A(Bz)-amidite; TNA-A(Bz)-CE-Phosphoramidite; DMTr-TNA A(Bz)-Phosphoramidite; N-Benzoyl-9-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]-9H-purine-6-amine; 1-{2'-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3'-O-[(4,4'-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine; (2R,3R,4S)-2-[6-(Benzoylamino)-9H. CAS No. 325683-93-0. Pack Sizes: 1 g. Product ID: B1370-376747. Molecular formula: C46H50N7O7P. Mole weight: 843.92. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine | 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is a biochemical compound widely used in the biomedical industry. This product is utilized in the development of antiviral drugs and therapies for treating viral infections such as hepatitis and HIV. Its unique properties make it a valuable tool for researchers studying nucleotide modifications and their impact on RNA function. Group: Pharmaceutical. Alternative Names: Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-; 2'-O-Methyl-3'-O-(tert-butyldimethylsilyl)uridine; 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-TBDMS-2'-OMe-U; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-methyluridine; 3'-TBDMS-2'-O-Me-rU. CAS No. 171268-84-1. Pack Sizes: 5 g. Product ID: B1370-072185. Molecular formula: C16H28N2O6Si. Mole weight: 372.49. Custom synthesis is available. Send your inquiries for more information. | London |
| 3'-O-tert-Butyldimethylsilyl-2'-deoxyadenosine | 3'-O-tert-Butyldimethylsilyl-2'-deoxyadenosine is a valuable reagent widely used in biomedical research, primarily utilized in the synthesis of nucleosides and nucleotides for studying DNA and RNA structures. Additionally, it finding application in drug design and discovery, targeting diseases such as cancer, viral infections is and genetic disorders. Group: Pharmaceutical. Alternative Names: 3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine; Adenosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-; ((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-2-yl)methanol; 2'-Deoxy-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine; 3'-O-TBDMS-2'-deoxyadenosine. CAS No. 51549-31-6. Pack Sizes: 1 g. Product ID: B1370-339189. Molecular formula: C16H27N5O3Si. Mole weight: 365.5. Custom synthesis is available. Send your inquiries for more information. | London |
| 4,4-Difluoro-8-pyridyl-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. CAS No. 1134484-25-5. Pack Sizes: 100 mg. Product ID: B1370-285109. Molecular formula: C18H18BF2N3. Mole weight: 325.16. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Thiouridine | Nucleotide analogue is essential to cell growth in certain bacterial species, which is also able to chelate with certain metal ions, and in tRNA. It can act as a built-in antiphotomutagenic agent protecting Escherichia coli cells against mutagenesis. Uses: Affinity labels. Group: Pharmaceutical. Alternative Names: Uridine, 4-thio-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one; 1-beta-D-ribofuranosyl-4-thiouracil; 1-(β-D-Ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone; 4-Thio Uridine. CAS No. 13957-31-8. Pack Sizes: 1 g. Product ID: B2706-009850. Molecular formula: C9H12N2O5S. Mole weight: 260.27. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(Azidomethyl)uridine | 5-(Azidomethyl)uridine, an indispensible compound in biomedicine with multifarious applications, emerges as an invaluable asset for scrutinizing nucleotide modifications and RNA interactions. The versatility of this product is unparalleled, manifesting as a proficient instrument for bioconjugation and labeling. Astutely employed in the quest to combat cancer, viral infections, and genetic disorders, it assumes a pivotal role in fostering novel therapeutic approaches. Group: Pharmaceutical. Alternative Names: Uridine, 5-(azidomethyl)-; 5-Azidomethyluridine. CAS No. 24751-67-5. Pack Sizes: 5 mg. Product ID: B1370-339136. Molecular formula: C10H13N5O6. Mole weight: 299.24. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences. Group: Pharmaceutical. Alternative Names: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5'-O-DMTr-2'-O-TBDMS-Pseudouridine-3'-CE Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-Pseudouridine-3'-cyanoethyl-Phosphoramidite. CAS No. 163496-23-9. Pack Sizes: 1 g. Product ID: B2706-337807. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Fluoro-UTP trisodium | 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug. Group: Pharmaceutical. Alternative Names: 5-Fluoro-uridine-5'-triphosphate trisodium; 5-F-UTP trisodium; 5-Fluorouridine 5'-(tetrahydrogen triphosphate) trisodium. Pack Sizes: 100 mg. Product ID: B1370-458983. Molecular formula: C9H14FN2Na3O15P3. Mole weight: 571.1. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-Hexynyl CE Phosphoramidite | 5'-Hexynyl CE Phosphoramidite, an essential reagent in biomedical research for oligonucleotide synthesis, offers versatility in sequencing modification through its alkyne functionality, enabling conjugation with diverse biomolecules. The reagent presents vast potential in critical fields such as gene therapy, drug discovery, and disease diagnosis and management. Its unique characteristics position it as a promising asset in achieving complex nucleotide sequencing, furthering our understanding of genetic health and disease. Group: Pharmaceutical. Alternative Names: 2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite; 5-Hexyn-1-yl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. CAS No. 1048985-37-0. Pack Sizes: 100 mg. Product ID: 1048985-37-0. Molecular formula: C15H27N2O2P. Mole weight: 298.37. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate Sodium | 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate Sodium is a nucleotide that can be used in DNA bioresearch and repair, as well as cancer treatment. It inhibits the synthesis of DNA by binding to the enzyme DNMT1 and causing it to lose its ability to produce DNA. It also suppresses RNA synthesis to induce cell death. Group: Pharmaceutical. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate monosodium; 5-hydroxymethyl-dUMP sodium. CAS No. 160509-68-2. Pack Sizes: 10 mg. Product ID: B2693-076438. Molecular formula: C10H14N2NaO9P. Mole weight: 360.19. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Hydroxymethyldeoxyuridylate | 5-Hydroxymethyldeoxyuridylate is a pivotal nucleotide in DNA bioresearch and repair, emerging as a substrate indispensable for diverse enzymes implicated in DNA methylation and demethylation cascades. Group: Pharmaceutical. Alternative Names: 5-hydroxymethyluridine-2'-deoxy-5'-phosphate; 5-hydroxymethyl-dUMP. CAS No. 5238-86-8. Pack Sizes: 10 mg. Product ID: B1370-376869. Molecular formula: C10H15N2O9P. Mole weight: 338.21. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-methyl-2'-deoxycytidine-5'-monophosphate | 5-methyl-2'-deoxycytidine-5'-monophosphate is a crucial compound in biomedicine used for various applications. As a modified nucleotide analogue, it plays a vital role in DNA methylation processes, making it fundamental for epigenetic studies and research. Additionally, this product is involved in the regulation of gene expression and has potential therapeutic significance in treating diseases such as cancer, neurodegenerative disorders, and viral infections. Group: Pharmaceutical. Alternative Names: 5-Me-2'-dCMP; 2'-Deoxy-5-methylcytidine-5'-monophosphate; 5-MedCMP; 2'-deoxy-5-methylcytidine 5'-(dihydrogen phosphate); 2'-deoxy-5-methyl-5'-cytidylic acid; 5-Methyl dCMP. CAS No. 2498-41-1. Pack Sizes: 50 mg. Product ID: B2706-298689. Molecular formula: C10H16N3O7P. Mole weight: 321.22. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a phosphoramidite reagent used to introduce 2-O-methyl modified U nucleotide into oligonucleotides. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite; 2'-OMe-U-CEP; 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)uridine. CAS No. 110764-79-9. Pack Sizes: 5 g. Product ID: B2706-081651. Molecular formula: C40H49N4O9P. Mole weight: 760.81. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite, a highly versatile and indispensable compound within the biomedical industry, occupies a paramount position in the synthesis of oligonucleotides of immense significance. Blending seamlessly with various applications including gene therapy, nucleic acid-based diagnostics, and drug development, this invaluable marvel propels the progress of medical science. Its inherent ability to modify nucleotide sequences bestows unmatched stability and facilitates target-specific drug conveyance, fostering advancements in the treatment of multifarious diseases, encompassing cancer and genetic disorders. Group: Pharmaceutical. Alternative Names: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-; 1-[2-O-(tert-Butyldimethylsilyl)-3-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-beta-L-ribofuranosyl]uracil; DMT-2'-O-TBDMS-L-rU Phosphoramidite; L-RNA 2'-OTBS U amidite; 5'-O-DMT-2'-O-TBDMS-L-U 3'-CE phosphoramidite. CAS No. 144490-31-3. Pack Sizes: 1 g. Product ID: B1370-291976. Molecular formula: C45H61N4O9PSi. Mole weight: 861.06. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-2'-O-tBDMS-N1-Methyl-N6-chloroacetyl-adenosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-tBDMS-N1-Methyl-N6-chloroacetyl-adenosine 3'-CE phosphoramidite, an essential instrument employed in scientific inquiry and pharmaceutical exploration, exhibits an exceptionally intricate nature. Primarily, this remarkable compound facilitates the creation of tailored DNA fragments, thereby accommodating a diverse range of research endeavors involving gene therapy and pharmaceutical conveyance mechanisms. Notably, our product assumes a pivotal role in the design and fabrication of nucleotide analogs, which serve as targeted interventions for critical maladies, including malignancies, viral infestations, and hereditary abnormalities. Group: Pharmaceutical. Pack Sizes: 1 g. Product ID: B1370-095533. Molecular formula: C49H65ClN7O8PSi. Mole weight: 974.59. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Group: Pharmaceutical. Alternative Names: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; DMT-2'-F-dC(Ac) amidite; DMT-2'Fluoro-dC(Ac) Phosphoramidite; DMT-2'-F-dC(Ac)-CE Phosphoramidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite; 2'-Fluoro-2'-deoxy Cytidine (n-ac) CED Phosphoramidite; 5'-O-DMT-2'-F-Acetyl-Deoxycytidine-CE Phosphoramidite; 5'-O-DMT-2'-F-dC(Ac) 3'-CE phosphoramidite. CAS No. 159414-99-0. Pack Sizes: 10 g. Product ID: B2706-395301. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. Custom synthesis is available. Send your inquiries for more information. | London |
| 5'-Thymidylic acid, disodium salt | 5'-Thymidylic acid, disodium salt is a paramount biomedical compound, playing the role of a nucleotide analog. It exerts its inhibitory prowess on viral DNA replication, thereby impeding the rampant multiplication of the virus. Group: Pharmaceutical. Alternative Names: Thymidine-5'-monophosphate disodium salt; sodium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate. CAS No. 33430-62-5. Pack Sizes: 5 g. Product ID: B2706-370401. Molecular formula: C10H13N2Na2O8P. Mole weight: 366.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Carboxyfluorescein | 6-Carboxyfluorescein (6-FAM) is a fluorescent dye used for labeling nucleotides and nucleic acids. Group: Pharmaceutical. Alternative Names: 6-FAM; (3,6,9-Trihydroxyxanthen-9-yl)terephthalic Acid; 3',6'-dihydroxy-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid. CAS No. 3301-79-9. Pack Sizes: 1 g. Product ID: B2708-090304. Molecular formula: C21H12O7. Mole weight: 376.32. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Carboxyfluorescein N-succinimidyl ester | 6-Carboxyfluorescein N-succinimidyl ester is the amine-reactive succinimidyl ester carboxyfluorescein that is used in the labeling of nucleotides and nucleic acids. Group: Pharmaceutical. Alternative Names: FAM NHS ester, 6-isomer;OSu-FAM; 6-FAM, SE; 6-FAM SE; 6-Carboxyfluorescein-NHS; 6-Carboxyfluorescein N-hydroxysuccinimide ester; (2,5-dioxopyrrolidin-1-yl) 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate. CAS No. 92557-81-8. Pack Sizes: 500 mg. Product ID: B0001-016064. Molecular formula: C25H15NO9. Mole weight: 473.393. Custom synthesis is available. Send your inquiries for more information. | London |
| 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Group: Pharmaceutical. Alternative Names: 7,8-Dimethoxy-1,2-dihydro-3H-3-benzazepin-2-one. CAS No. 73942-87-7. Pack Sizes: 1mg;1g;10g. Product ID: NP3533. Molecular formula: C12H13NO3. Mole weight: 219.24. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Deaza-dGTP 10mM Sodium Solution | 7-Deaza-dGTP is a nucleotide analogue, unveiling profound insights into the intricate mechanisms governing DNA research and development and repair. Moreover, it serving as an invaluable investigative tool in comprehending the multifaceted nature of viral replication while manifesting promising inhibitory capacities. Group: Pharmaceutical. Alternative Names: sodium 7-deaza-2'-deoxyguanosine-5'-triphosphate. Pack Sizes: 100 ul. Product ID: B1370-459001. Molecular formula: C11H13N4Na4O13P3. Mole weight: 594.12. Custom synthesis is available. Send your inquiries for more information. | London |
| 7-Methylguanosine | 7-Methylguanosine is a modified form of the purine nucleotides. When present in human urine, it may be a biomarker for certain cancers. Group: Pharmaceutical. Alternative Names: N7-Methylguanosine; 1H-Purinium, 2-amino-6,9-dihydroxy-7-methyl-6-oxo-9-b-D-ribofuranosyl-; Purinium, 2-amino-1,6,-dihydroxy-7-methyl-6-oxo-9-β-D-ribofuranosyl-; Guanosine, 7-Methyl-. CAS No. 20244-86-4. Pack Sizes: 100 mg. Product ID: B1370-062405. Molecular formula: C11H16N5O5. Mole weight: 298.28. Custom synthesis is available. Send your inquiries for more information. | London |
| 8(4'-bromophenyl)-1,3,5,7-tetramethyl-BODIPY | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 8-(4-Bromophenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene. CAS No. 850534-66-6. Pack Sizes: 10 mg. Product ID: B2708-285104. Molecular formula: C19H18BBrF2N2. Mole weight: 403.077. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Azanebularine CE-Phosphoramidite | DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite is a chemical compound used in oligonucleotide synthesis. It protects the 5'-hydroxyl group with a DMTr group and stabilizes the ribose sugar with a 2'-O-TBDMS modification. Additionally, it incorporates 8-azanebularine as a modified nucleoside. The 3'-CE phosphoramidite facilitates nucleotide addition during synthesis. This compound allows for the controlled synthesis of oligonucleotides with specific modifications, important for various applications in molecular biology and biotechnology. Group: Pharmaceutical. Alternative Names: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite. CAS No. 771494-03-2. Pack Sizes: 50 mg. Product ID: B1370-087581. Molecular formula: C45H60N7O7PSi. Mole weight: 870.08. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Group: Pharmaceutical. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. CAS No. 475205-49-3. Pack Sizes: 1mg;1g;10g. Product ID: 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A(Ac)-TOM-CE Phosphoramidite | 2'-O-TOM-A(Ac) Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It features a 2'-O-TOM (2'-O-tomc) modification attached to an adenosine (A) nucleotide, along with an acetyl (Ac) group. This modification enhances stability and protects against nuclease degradation. It is often employed in applications such as RNA interference, gene expression modulation, and therapeutic RNA-based treatments. The synthesis of RNA using monomers containing the 2'-O-Triisopropylsilyloxymethyl (TOM) group (TOM-Protecting-Group) has very high coupling efficiency along with fast, simple deprotection. Group: Pharmaceutical. Alternative Names: 5'-Dimethoxytrityl-N-acetyl-Adenosine, 2'-O-triisopropylsilyloxymethyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Acetyl-2'-O-[(triisopropylsilyloxy)methyl]-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)adenosine; Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[[tris(1-methylethyl)silyl]oxy]methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methyleth. CAS No. 253586-13-9. Pack Sizes: 1mg;1g;10g. Product ID: 253586-13-9. Molecular formula: C52H72N7O9PSi. Mole weight: 998.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-rC Phosphoramidite | Ac-rC Phosphoramidite is a commonly used protected 2-OTBDMS phosphoramidite for incorporating cytidine nucleotides into synthetic oligonucleotides. Group: Pharmaceutical. Alternative Names: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine 3'-CE phosphoramiditee; 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl-2'-O-t-butyldimethylsilylcytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite; DMT-2'-O-TBDMS-rC(ac) Phosphoramidite; 2'-TBDMS-Ac-rC-CE-Phosphoramidite; 5'-DMT-2'-O-TBDMS-N4-Acetyl-Cytidine Phosphoramidite. CAS No. 121058-88-6. Pack Sizes: 25 g. Product ID: B1370-082410. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11. Custom synthesis is available. Send your inquiries for more information. | London |
| Atractyloside potassium salt | Atractyloside potassium salt is the potassium salt of atractyloside, which inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane. Uses: Inhibitor of the adenine nucleotide translocator (ant). Group: Pharmaceutical. Alternative Names: (2b,4a,15a)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt; Atractylic acid dipotassium salt; Atractylin (C30 glucoside). CAS No. 102130-43-8. Pack Sizes: 20 mg. Product ID: B0005-158965. Molecular formula: C30H44K2O16S2. Mole weight: 802.99. Custom synthesis is available. Send your inquiries for more information. | London |
| BDY FL, SE | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: 3-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 7-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; 4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Propionic Acid, Succinimidyl Ester; BDP FL NHS ester. CAS No. 146616-66-2. Pack Sizes: 50 mg. Product ID: B0245-118888. Molecular formula: C18H18BF2N3O4. Mole weight: 389.166. Custom synthesis is available. Send your inquiries for more information. | London |
| BI-3406 | BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Group: Pharmaceutical. Alternative Names: BI 3406; BI3406. CAS No. 2230836-55-0. Pack Sizes: 5 mg. Product ID: B2693-363125. Molecular formula: C23H25F3N4O3. Mole weight: 462.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Biotin-dT CE-Phosphoramidite | Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques. Group: Pharmaceutical. Alternative Names: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT. CAS No. 198080-40-9. Pack Sizes: 250 mg. Product ID: B1370-207576. Molecular formula: C69H89N8O12PS. Mole weight: 1285.55. Custom synthesis is available. Send your inquiries for more information. | London |
| BODIPY 493/503 NHS Ester | BODIPY 493/503 NHS Ester is a green-fluorescent dye that is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers, and other amine-containing biomolecules. This compound is relatively insensitive to environment and pH changes. Group: Pharmaceutical. Alternative Names: 10-(3-((2,5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide. CAS No. 216961-98-7. Pack Sizes: 100 mg. Product ID: B1370-285334. Molecular formula: C20H22BF2N3O4. Mole weight: 417.22. Custom synthesis is available. Send your inquiries for more information. | London |
| BODIPY 576/589 SE | BODIPY 576/589 SE is a red-fluorescent dye that is reactive with primary amines on peptides, proteins, modified nucleotides, biopolymers and other amine-containing biomolecules. It is non-ionic, and relatively insensitive to environment and pH changes. Group: Pharmaceutical. Alternative Names: Py-BODIPY-NHS ester. CAS No. 201998-61-0. Pack Sizes: 25 mg. Product ID: F01-0188. Molecular formula: C20H17BF2N4O4. Mole weight: 426.18. Custom synthesis is available. Send your inquiries for more information. | London |
| Brequinar sodium | Brequinar sodium is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ~20 nM), which causes the blockade of de novo pyrimidine nucleotide biosynthesis. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: Dup785; Dup 785; Dup-785; Brequinar Sodium. 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium; Dup 785. CAS No. 96201-88-6. Pack Sizes: 50 mg. Product ID: B2693-305415. Molecular formula: C23H14F2NO2Na. Mole weight: 397.35. Custom synthesis is available. Send your inquiries for more information. | London |
| BzATP triethylammonium salt | The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5-10 fold greater potency than ATP with EC50 of 0.7 μM. It also exhibits partial agonist activity at P2X1 and P2Y1 receptors. BzATP can also be used as a photoaffinity probe to study adenine nucleotide binding to ATPases. Group: Pharmaceutical. Alternative Names: BzATP; Benzoylbenzoic adenosine 5'-triphosphate. CAS No. 112898-15-4. Pack Sizes: 25 mg. Product ID: B2693-359261. Molecular formula: C30H39N6O15P3. Mole weight: 816.6. Custom synthesis is available. Send your inquiries for more information. | London |
| CMP-Neu5Az sodium | CMP-Neu5Az is a modified sialic acid nucleotide commonly used in glycosylation research, particularly for bioorthogonal labeling and metabolic engineering of sialic acids. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-458994. Molecular formula: C20H28N7Na2O16P. Mole weight: 699.43. Custom synthesis is available. Send your inquiries for more information. | London |
| Diethyl Tenofovir | One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Group: Pharmaceutical. Alternative Names: (R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine; P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid Diethyl Ester; [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid Diethyl Ester. CAS No. 180587-75-1. Pack Sizes: 100 mg. Product ID: B1707-234697. Molecular formula: C13H22N5O4P. Mole weight: 343.33. Custom synthesis is available. Send your inquiries for more information. | London |
| GDP-D-mannose disodium salt | GDP-D-mannose disodium salt is an invaluable compound, playing a pivotal role in the research of disorders pertaining to compromised glucose metabolism. Functioning as a critical intermediate within biosynthetic pathways, it specifically facilitates the synthesis of sugar nucleotides. Group: Pharmaceutical. Alternative Names: Guanosine 5-diphospho-D-mannose disodium salt; GDP-Man; Guanosine 5'-(trihydrogen diphosphate), P'-D-mannopyranosyl ester, disodium salt. CAS No. 103301-73-1. Pack Sizes: 50 mg. Product ID: B2705-358025. Molecular formula: C16H23N5O16P2Na2. Mole weight: 649.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Golgicide A | Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1. Golgicide A inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to the nuclear periphery. Group: Pharmaceutical. Alternative Names: GCA; (3aR,9bS)-rel-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-, (3aR,9bS)-. CAS No. 1139889-93-2. Pack Sizes: 100 mg. Product ID: B1370-261662. Molecular formula: C17H14F2N2. Mole weight: 284.3. Custom synthesis is available. Send your inquiries for more information. | London |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Group: Pharmaceutical. Alternative Names: 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile; Remdesivir metabolite GS-441524; GS 441524; GS441524; (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. CAS No. 1191237-69-0. Pack Sizes: 5 g. Product ID: B2693-012542. Molecular formula: C12H13N5O4. Mole weight: 291.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Guanosine 3',5'-cyclic monophosphate | Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Group: Pharmaceutical. Alternative Names: 3:5-CGMP; D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate. CAS No. 7665-99-8. Pack Sizes: 250 mg. Product ID: B1370-013547. Molecular formula: C10H12N5O7P. Mole weight: 345.21. Custom synthesis is available. Send your inquiries for more information. | London |
| hsa-miR-146a-5p agomir | hsa-miR-146a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo. Group: Pharmaceutical. Pack Sizes: 5 nmol. Product ID: B1370-449810. Mole weight: 15104.36. Custom synthesis is available. Send your inquiries for more information. | London |
| hsa-miR-146a-5p Inhibitor | hsa-miR-146a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. hsa-miR-146a-5p inhibitors have full-length nucleotide 2'-methoxy modification. They strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Group: Pharmaceutical. Pack Sizes: 5 nmol. Product ID: B1370-449809. Mole weight: 6592.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Group: Pharmaceutical. Alternative Names: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. CAS No. 50847-11-5. Pack Sizes: 5 g. Product ID: B0084-329045. Molecular formula: C14H18N2O. Mole weight: 230.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Ivabradine hydrochloride | Ivabradine is a medication of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It is used for the treatment of symptomatic management of stable heart-related chest pain and heart failure. Group: Pharmaceutical. Alternative Names: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. CAS No. 148849-67-6. Pack Sizes: 5 g. Product ID: NP3530. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. Custom synthesis is available. Send your inquiries for more information. | London |
| Ivabradine Impurity 15 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Group: Pharmaceutical. Alternative Names: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-4,5-dihydro-7,8-dimethoxy-1H-3-benzazepine-1,2(3H)-dione; 2-Oxo-ivabradine Hydrochloride. CAS No. 1616710-50-9. Pack Sizes: 10 mg. Product ID: B2694-343856. Molecular formula: C27H35ClN2O6. Mole weight: 519.03. Custom synthesis is available. Send your inquiries for more information. | London |
| meso-CH2Br-BODIPY | BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. Group: Pharmaceutical. Alternative Names: BODIPY 493/503 Methyl Bromide; 8-Bromomethyl-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-S-indacene. CAS No. 216434-81-0. Pack Sizes: 10 mg. Product ID: B1370-102399. Molecular formula: C14H16BBrF2N2. Mole weight: 341.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl b-D-ribofuranoside | Methyl b-D-ribofuranoside, a widely employed biomedical product in research and diagnostics, stands as a synthetic sugar compound intricately resembling a crucial fragment of both RNA and DNA. Its application extends to exploring the repercussions of nucleotide alterations and serving as a standard compound in nucleic acid synthesis. Moreover, its usage exhibits promise in antiviral drug development and unraveling intricate cellular mechanisms entailing nucleic acids. Group: Pharmaceutical. Alternative Names: Methyl beta-D-ribofuranoside; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-methoxy-tetrahydrofuran-3,4-diol. CAS No. 7473-45-2. Pack Sizes: 50 g. Product ID: B1370-076364. Molecular formula: C6H12O5. Mole weight: 164.16. Custom synthesis is available. Send your inquiries for more information. | London |
| N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine | An impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Group: Pharmaceutical. Alternative Names: GS 7160. CAS No. 376633-24-8. Pack Sizes: 50 mg. Product ID: B2694-085564. Molecular formula: C12H19N6O5P. Mole weight: 358.29. Custom synthesis is available. Send your inquiries for more information. | London |
| N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite | N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, a fundamental component in the field of biomedical research, plays a vital role in the synthesis of modified nucleotides. This indispensable compound finds wide applicability in the creation and investigation of nucleic acid-derived pharmaceuticals, with particular focus on the exploration and mitigation of viral infections, malignancies, and hereditary anomalies. Group: Pharmaceutical. Alternative Names: N-Acetyl-5'-(4,4'-dimethoxytrityl)-5-methyl-2'-deoxycytidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-Methyl-dC(ac) amidite; DMT-5-Methyl-dC(ac) Phosphoramidite; 5'-O-DMT-N4-Acetyl-5-Methyl-2'-deoxycytidine 3'-CE phosphoramidite; 5'-DMT-N4-Ac-5-Me-dC phosphoramidite; N4-Acetyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-cyanoethyl phosphoramidite. CAS No. 1873306-74-1. Pack Sizes: 1 g. Product ID: B1370-337644. Molecular formula: C42H52N5O8P. Mole weight: 785.86. Custom synthesis is available. Send your inquiries for more information. | London |
| N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite | N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is widely used in the biomedical industry as a building block for synthesizing modified nucleotides. It plays a crucial role in the research of pharmaceutical drugs targeting specific diseases, such as cancer and viral infections. Group: Pharmaceutical. Alternative Names: 5'-Dimethoxytrityl-N-benzoyl-5-methyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N4-Bz-5'-DMT-5-Me-dC phosphoramidite; N4-Benzoyl-2'-Deoxy-5'-O-DMT-5-methyl-D-cytidine 3'-CE phosphoramidite; N4-Benzoyl-5'-O-DMT-5-methyl-2'-Deoxycytidine 3'-CE phosphoramidite; 5-Me-dC-CE Phosphoramidite. CAS No. 105931-57-5. Pack Sizes: 5 g. Product ID: B1370-155120. Molecular formula: C47H54N5O8P. Mole weight: 847.93. Custom synthesis is available. Send your inquiries for more information. | London |
| N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite | N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite can be used to incorporate 2-fluoro modified nucleotides into oligonucleotides, improving metabolic stability. Group: Pharmaceutical. Alternative Names: 2'-Fluoro-dA CEP; 2'-Fluoro-Bz-A-CEP; N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-adenosine 3'-CE phosphoramidite; N6-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxyadenosine 3'-CE phosphoramidite; DMT-2'-F-dA(Bz)-CE-Phosphoramidite; N6-Bz-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite. CAS No. 136834-22-5. Pack Sizes: 10 g. Product ID: B2706-291972. Molecular formula: C47H51FN7O7P. Mole weight: 875.95. Custom synthesis is available. Send your inquiries for more information. | London |
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