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1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-b-D-glucopyranose, a key constituent within the biomedical sector, assumes a pivotal function as a precursor for synthesizing diverse antiviral nucleosides. This compound holds tremendous importance in the advancement of antiviral medications targeting ailments arising from viral infections. Group: Pharmaceutical. Alternative Names: 2-Azido-b-D-glucose tetraacetate; 2-Azido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl acetate. CAS No. 80321-89-7. Pack Sizes: 1 g. Product ID: B2705-135231. Molecular formula: C14H19N3O9. Mole weight: 373.32. Custom synthesis is available. Send your inquiries for more information.
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1-(b-D-Xylofuranosyl)uracil
1-(b-D-Xylofuranosyl)uracil, a potent nucleoside analogue, has proven efficacy in treating herpes simplex virus infections as an antiviral agent. Its active mechanism, closely resembling that of natural nucleosides, gives it the ability to impair viral replication, making it a promising therapeutic option for herpes simplex infections. Group: Pharmaceutical. Alternative Names: Xylo-uridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(beta-D-Xylofuranosyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 1-β-D-xylofuranosyl-; 9-(β-D-Xylofuranosyl)uracil; 1-β-D-Xylofuranosyl-2,4(1H,3H)-pyrimidinedione; 1-Xylosyluracil; 1-β-D-Xylofuranosyluracil; 1-β-D-Xylosyluracil; β-D-Xylouracil. CAS No. 16535-78-7. Pack Sizes: 5 mg. Product ID: B2706-022401. Molecular formula: C9H12N2O6. Mole weight: 244.2. Custom synthesis is available. Send your inquiries for more information.
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1-Methyladenosine
1-Methyladenosine is a modified nucleoside often found in tRNAs and rRNA. In the biomedical industry, it is pivotal for protein synthesis, cellular function, and responses to stressors. It's also being studied concerning viral RNA methylation in diseases such as hepatitis C. Group: Pharmaceutical. Alternative Names: Adenosine, 1-methyl-; N1-Methyladenosine; N1-Methyl-D-adenosine; NSC 92165; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)tetrahydrofuran-3,4-diol; Adenosine, N,6-didehydro-1,9-dihydro-1-methyl-. CAS No. 15763-06-1. Pack Sizes: 500 mg. Product ID: B1370-363540. Molecular formula: C11H15N5O4. Mole weight: 281.27. Custom synthesis is available. Send your inquiries for more information.
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2',3'-Dideoxy-3'-fluorouridine
2',3'-Dideoxy-3'-fluorouridine is a reactant used in the synthesis of 5'-trityl nucleosides to inhibit Plasmodium falciparum dUTPase. It exhibits anti-retrovirus activity. Group: Pharmaceutical. Alternative Names: Fddurd; 3'-Fluoro-2',3'-dideoxyuridine; 3'-FddU; 2,4(1H,3H)-Pyrimidinedione, 1-(2,3-dideoxy-3-fluoro-b-D-erythro-pentofuranosyl)-; 1-((2R,4S,5R)-4-Fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2,3-Dideoxy-3-fluoro-beta-D-ribofuranosyl)-uracil; 1-(2,3-dideoxy-3-fluoro-beta-D-erythropentofuranosyl)uracil. CAS No. 41107-56-6. Pack Sizes: 100 mg. Product ID: B2706-316809. Molecular formula: C9H11FN2O4. Mole weight: 230.19. Custom synthesis is available. Send your inquiries for more information.
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2',3'-Dideoxyguanosine
2',3'-Dideoxyguanosine is a nucleoside analog. It executes an impeding stratagem against replication by skillfully substituting naturally occurring nucleosides within the viral DNA, hence obstructing its ambulatory growth. Uses: Antiviral agents. Group: Pharmaceutical. Alternative Names: Guanosine, 2',3'-dideoxy-; Dideoxyguanosine. CAS No. 85326-06-3. Pack Sizes: 250 mg. Product ID: B1370-139095. Molecular formula: C10H13N5O3. Mole weight: 251.24. Custom synthesis is available. Send your inquiries for more information.
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2',5'-Dideoxy adenosine
2',5'-Dideoxy adenosine is a nucleoside analog that is one of the first identified cell-permeable, P-site inhibitors of adenylate cyclase. It inhibits forskolin-induced activation of a cAMP-dependent reporter gene in HEK293 cells with an IC50 value of 33 μM. Group: Pharmaceutical. Alternative Names: 2?,5?-dd-Ado; Adenosine, 2',5'-dideoxy-; (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-methyltetrahydrofuran-3-ol. CAS No. 6698-26-6. Pack Sizes: 100 mg. Product ID: B1370-190625. Molecular formula: C10H13N5O2. Mole weight: 235.24. Custom synthesis is available. Send your inquiries for more information. Categories: 2',5'-Dideoxyadenosine.
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2'-Amino-2'-deoxy-b-D-arabino-5-methyluridine
2'-Amino-2'-deoxy-b-D-arabino-5-methyluridine is a nucleoside analog with the ability to inhibit viral reverse transcriptase and DNA polymerase activities. It has been used in the development of antiviral drugs for the treatment of HIV and hepatitis B and C infections. Additionally, it has been studied for its potential use in cancer therapy due to its ability to induce apoptosis in cancer cells. Group: Pharmaceutical. Alternative Names: 2,4(1H,3H)-Pyrimidinedione, 1-(2-amino-2-deoxy-β-D-arabinofuranosyl)-5-methyl-; 2'-Amino-2'-deoxy-β-D-arabino-5-methyluridine. CAS No. 135304-48-2. Pack Sizes: 10 mg. Product ID: B1370-039073. Molecular formula: C10H15N3O5. Mole weight: 257.24. Custom synthesis is available. Send your inquiries for more information.
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2'-Amino-2'-deoxyuridine
2'-Amino-2'-deoxyuridine, a nucleoside analogue, finds its use in chemotherapy as an anti-cancer agent. Its ability to cause DNA damage and trigger apoptosis in cancer cells stem from its selective integration in cancer cell DNA. Additionally, it offers immense potential in the field of oncology research, studying tumor cell differentiation and proliferation. Group: Pharmaceutical. Alternative Names: 2'-Amino-2'-deoxy-D-uridine; 2'-deoxy-2'-amino-uridine; 2,4(1H,3H)-pyrimidinedione, 1-(2-amino-2-deoxy-b-D-ribofuranosyl)-; 1-[(2R,3R,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. CAS No. 26889-39-4. Pack Sizes: 1 g. Product ID: B2706-089006. Molecular formula: C9H13N3O5. Mole weight: 243.22. Custom synthesis is available. Send your inquiries for more information.
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2'-b-C-Methyl-6-azauridine
2'-b-C-Methyl-6-azauridine, a nucleoside analogue prodrug, exhibits a robust anti-Hepatitis C virus activity by hindering RNA synthesis and impeding viral replication. In addition, this agent displays tremendous potential in the management of other viral ailments. Group: Pharmaceutical. Alternative Names: 2'-β-C-Methyl-6-azauridine; 2'-Methyl-6-azauridine; 2-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione; 2-(2-C-Methyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione. CAS No. 172605-95-7. Pack Sizes: 50 mg. Product ID: B1370-052708. Molecular formula: C9H13N3O6. Mole weight: 259.22. Custom synthesis is available. Send your inquiries for more information.
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2'-Chloro-2'-deoxyadenosine
2'-Chloro-2'-deoxyadenosine, an essential nucleoside analog in the biomedical field, exhibits profound therapeutic potential for the treatment of diverse ailments, encompassing specific leukemias and lymphomas. By impairing DNA synthesis and instigating apoptosis in malignant cells, this medication emerges as an indispensable asset in combating these pernicious diseases, heralding optimism for the enhancement of patient prognoses. Group: Pharmaceutical. Alternative Names: 2'-chlorodeoxyadenosine; 2'-Deoxy-2'-chloroadenosine; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-chloro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 2627-62-5. Pack Sizes: 10 mg. Product ID: B1370-339143. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-2'-fluoro-5-iodouridine
It is an antiviral drug and nucleoside analogue with anti-hepatitis B activity. Group: Pharmaceutical. Alternative Names: 1-(2'-Deoxy-2'-fluoro-beta-D-ribofuranosyl)-5-iodouracil; 2'-epi-Fialuridine; FIRU; 5-Iodo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracil; 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione. CAS No. 55612-21-0. Pack Sizes: 100 mg. Product ID: B1370-261441. Molecular formula: C9H10FIN2O5. Mole weight: 372.09. Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-2'-fluoroarabinoadenosine
As an analog of the antitumour and antiviral naturally occurring nucleoside 9-(β-D-arabinofuranosyl)adenine (ara-A), 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine inhibited the growth of T. vaginalis with an IC50 of 0.09μM. Uses: Anti-neoplastic; inhibits the growth of t. vaginalis with an ic50 of 0.09μm. Group: Pharmaceutical. Alternative Names: 20227-41-2;9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;arabino-F-Ado;CHEMBL2032002;(2R,3R,4S,5R)-5-(6-AMINOPURIN-9-YL)-4-FLUORO-2-(HYDROXYMETHYL)OXOLAN-3-OL;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;C10H12FN5O3;SCHEMBL1389499;123334-75-8;BDBM50452569;MFCD12911815;2??-Deoxy-2??-fluoroarabinoadenosine;AKOS027327937;AC-32315;AS-68707;F13969;A855629;2 inverted exclamation mark -Deoxy-2 inverted exclamation mark -fluoroarabinoadenosine;(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine. CAS No. 20227-41-2. Pack Sizes: 200 mg. Product ID: B0084-086977. Molecular formula: C26H30N2O5. Mole weight: 450.5. Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-4'-ethynyl-2-fluoroadenosine
Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: EFdA; 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine. CAS No. 865363-93-5. Pack Sizes: 10 mg. Product ID: B2705-038148. Molecular formula: C12H12FN5O3. Mole weight: 293.25. Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-5-methoxyuridine
2'-Deoxy-5-methoxyuridine is a nucleoside analog with antiviral potency. It can selectively inhibit the replication of viral genetic material and has been shown to be effective against HIV-1. Group: Pharmaceutical. Alternative Names: 5-methoxy-2'-deoxy-uridine; uridine, 2'-deoxy-5-methoxy-. CAS No. 37805-95-1. Pack Sizes: 10 mg. Product ID: B1370-058151. Molecular formula: C10H14N2O6. Mole weight: 258.23. Custom synthesis is available. Send your inquiries for more information.
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2'-Deoxy-N2,N2-dimethylguanosine
2'-Deoxy-N2,N2-dimethylguanosine is a vital reagent used in biomedicine for research purposes. It acts as a nucleoside analogue and exhibits potential antiviral activity against certain RNA viruses. This product is often utilized in the development of antiviral drugs and studying their mechanisms of action. With its unique properties, 2'-Deoxy-N2,N2-dimethylguanosine holds promise in advancing biomedical research in virology and drug discovery. Group: Pharmaceutical. Alternative Names: 2'-Deoxy-N,N-dimethylguanosine; 2-(Dimethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2'-Deoxy-N2-dimethylguanosine. CAS No. 88127-22-4. Pack Sizes: 10 g. Product ID: B1370-340303. Molecular formula: C12H17N5O4. Mole weight: 295.29. Custom synthesis is available. Send your inquiries for more information.
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2'-O,4'-C-Methyleneguanosine
2'-O,4'-C-Methyleneguanosine, a modified nucleoside molecule, has demonstrated effective outcomes in the domain of antiviral therapeutics, exemplifying excellent potential as a therapeutic agent for hepatitis C and West Nile virus infections. Substantiated by its unique mechanism of action- hindering viral RNA polymerase, a critical enzyme necessary for viral replication, it is deemed a highly potent approach for viral inhibition. Furthermore, this particular compound presents an enticing opportunity for its application as an antitumor agent, drawing interest from scientific communities. Group: Pharmaceutical. Alternative Names: LNA-G; 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine; 2-Amino-9-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one. CAS No. 207131-16-6. Pack Sizes: 100 mg. Product ID: B2706-038100. Molecular formula: C11H13N5O5. Mole weight: 295.25. Custom synthesis is available. Send your inquiries for more information.
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2'-O-Methyladenosine
2'-O-Methyladenosine is a modified nucleoside where a methyl group is attached to the 2' hydroxyl of the ribose sugar. This modification enhances the stability and binding affinity of RNA molecules, making it valuable in research focused on RNA structure, function, and therapeutic development. It is commonly used in the synthesis of chemically modified RNA for studies in molecular biology and biotechnology. Group: Pharmaceutical. Alternative Names: Adenosine, 2'-O-methyl-; (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Cordysinin B; 2'-O-Methyl-D-adenosine; 2'-O-Me-adenosine; 2'-(O-Methyl) Adenosine; 2'-O-Me-Ado. CAS No. 2140-79-6. Pack Sizes: 25 g. Product ID: B1370-336353. Molecular formula: C11H15N5O4. Mole weight: 281.27. Custom synthesis is available. Send your inquiries for more information.
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2'-O-Methylcytidine
Cytidine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase. Group: Pharmaceutical. Alternative Names: 2'-(O-Methyl) Cytidine; Cytidine, 2'-O-methyl-; 2'-O-Methyl cytidine; O(2')-Methylcytidine; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-Amino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-one. CAS No. 2140-72-9. Pack Sizes: 25 g. Product ID: B1370-187735. Molecular formula: C10H15N3O5. Mole weight: 257.24. Custom synthesis is available. Send your inquiries for more information.
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2'-O-Methyluridine
Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication. Group: Pharmaceutical. Alternative Names: 2'-(O-Methyl) Uridine; Uridine, 2'-O-methyl-; O(2')-Methyluridine; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-O-Methyl-β-D-ribofuranosyl)uracil. CAS No. 2140-76-3. Pack Sizes: 25 g. Product ID: B2706-309048. Molecular formula: C10H14N2O6. Mole weight: 258.23. Custom synthesis is available. Send your inquiries for more information.
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2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite
2'-tBDSilyl Adenosine (n-PAC) CED Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It incorporates a 2'-tert-butyldimethylsilyl (tBDSilyl) group onto the adenosine (A) nucleoside at the 2'-position. Additionally, it features a nitrilotriacetic acid (n-PAC) group for chelating metal ions and a controlled-efficiency (CED) phosphoramidite for efficient incorporation during solid-phase synthesis. This reagent enables the production of modified RNA oligonucleotides with improved stability and functionality, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies. Group: Pharmaceutical. Alternative Names: PAC-rA CEP; N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, 5'-O-. CAS No. 121058-86-4. Pack Sizes: 1 g. Product ID: B1370-008561. Molecular formula: C54H68N7O9PSi. Mole weight: 1018.22. Custom synthesis is available. Send your inquiries for more information.
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2-Thiouridine
2-Thiouridine, an esteemed biomedical marvel, is renowned for its profound efficacy in combatting malignant neoplasms and thwarting viral affections. This exalted nucleoside derivative ingeniously integrates itself into RNA, instigating the impeding of viral propagation and invoking apoptosis within neoplastic entities. Its exceptional anti-tumorigenic and antiviral prowess has propelled 2-Thiouridine to the vanguard of biomedical exploration and therapeutic breakthroughs. Group: Pharmaceutical. Alternative Names: 1-β-D-Ribofuranosyl-2-thiouracil; 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; Thiouridine. CAS No. 20235-78-3. Pack Sizes: 1 g. Product ID: B1370-331350. Molecular formula: C9H12N2O5S. Mole weight: 260.27. Custom synthesis is available. Send your inquiries for more information.
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3'-Amino-3'-deoxyuridine
3'-Amino-3'-deoxyuridine, a multifaceted compound extensively utilized in the biomedical sector, assumes a pivotal function in the fabrication of antiviral medications, specifically those combatting DNA viruses such as herpes simplex virus (HSV). Moreover, it serves as a fundamental constituent in the formulation of nucleoside analogs, augmenting their efficacy in combating viral ailments, including cancer. Group: Pharmaceutical. Alternative Names: Uridine, 3'-amino-3'-deoxy-; 1-((2R,3R,4S,5S)-4-amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 70580-90-4. Pack Sizes: 100 mg. Product ID: B2706-337977. Molecular formula: C9H13N3O5. Mole weight: 243.22. Custom synthesis is available. Send your inquiries for more information.
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3'-Azido-3'-deoxyguanosine
3'-Azido-3'-deoxyguanosine is an exceptionally robust antiviral compound meticulously formulated to intricately impede the microbial replication process by precisely directing its attention towards the viral DNA polymerase, disallowing its maleficent progression. Expertly synthesized, this quintessential nucleoside analogue incessantly finds application within the biomedical sector for its unprecedented multiplicity within research domains pertaining to antiviral pharmaceutical evolution and the efficacious research of viral ailments, most notably retroviruses and herpes viruses induced afflictions. Group: Pharmaceutical. Alternative Names: AZDG; 2-amino-9-[(2R,3R,4S,5S)-4-azido-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one; 3'-Deoxy-3'-azidoguanosine; 6H-Purin-6-one, 2-amino-9-(3-azido-3-deoxy-beta-D-ribofuranosyl)-1,9-dihydro-. CAS No. 98870-11-2. Pack Sizes: 50 mg. Product ID: B1370-064370. Molecular formula: C10H12N8O4. Mole weight: 308.25. Custom synthesis is available. Send your inquiries for more information.
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3'-Deoxy-3'-fluorocytidine
3'-Deoxy-3'-fluorocytidine is a purine nucleoside analogue. It is an antiviral agent. Group: Pharmaceutical. Alternative Names: Cytidine, 3-deoxy-3-fluoro-; 3'-Fluoro-3'-deoxycytidine; 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine; 4-amino-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-3,4-dihydropyrimidin-2(1H)-one; 3'-F-3'-Dc. CAS No. 123402-20-0. Pack Sizes: 5 mg. Product ID: B1370-279821. Molecular formula: C9H12FN3O4. Mole weight: 245.21. Custom synthesis is available. Send your inquiries for more information.
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3-Formylindole-2'-deoxyriboside
3-Formylindole-2'-deoxyriboside is an indispensable biomedical entity, particularly used in research of cancer. Serving as a paramount synthetic nucleoside analog, it harmoniously orchestrates the symphony of inhibiting malignant cell proliferation. Group: Pharmaceutical. Alternative Names: 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-indole-3-carbaldehyde; 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1H-indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-. CAS No. 460355-03-7. Pack Sizes: 100 mg. Product ID: B1370-071180. Molecular formula: C14H15NO4. Mole weight: 261.27. Custom synthesis is available. Send your inquiries for more information.
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3'-O-(2-Methoxyethyl)guanosine
3'-O-(2-Methoxyethyl)guanosine is a remarkable modified nucleoside with immense potential in the field of antiviral drug discovery. This exquisite compound takes center stage in targeting viral RNA-dependent RNA polymerases, thus rendering it a powerful weapon in research of respiratory syncytial virus (RSV) and hepatitis C virus (HCV). Group: Pharmaceutical. Alternative Names: Guanosine, 3'-O-(2-methoxyethyl)-; 3'-O-MOE-G; 2-Amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one. CAS No. 256224-03-0. Pack Sizes: 2 g. Product ID: B1370-038131. Molecular formula: C13H19N5O6. Mole weight: 341.32. Custom synthesis is available. Send your inquiries for more information.
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3'-O-Methylguanosine
3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Group: Pharmaceutical. Alternative Names: 3'-(O-Methyl) Guanosine; 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one. CAS No. 10300-27-3. Pack Sizes: 50 mg. Product ID: B2706-306475. Molecular formula: C11H15N5O5. Mole weight: 297.27. Custom synthesis is available. Send your inquiries for more information.
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3'-O-(t-Butyldimethylsilyl)thymidine
3'-O-(t-Butyldimethylsilyl)thymidine, a highly significant compound within the biomedicine sector, plays a pivotal role due to its extensive usage across diverse applications. Notably, this compound serves as a precursor in the synthesis of potent antiviral medications exemplified by AZT, renowned for its efficacy in the treatment of HIV/AIDS. By virtue of its strategic involvement in nucleoside analogue development, this compound emerges as a crucial catalyst, propelling scientific investigations into the combat against viral afflictions and the elucidation of their intricate mechanisms of function. Group: Pharmaceutical. Alternative Names: 3'-O-t-Bulyldimethylsilyl-thymidine; 1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 3'-O-(tert-butyldimethylsilyl)thymidine; Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3'-O-(TBDMS)Thymidine; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]thymidine; 3'-DiTBSRiboT. CAS No. 40733-27-5. Pack Sizes: 10 g. Product ID: B2706-207659. Molecular formula: C16H28N2O5Si. Mole weight: 356.49. Custom synthesis is available. Send your inquiries for more information.
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3'-O-tert-Butyldimethylsilyl-2'-deoxyadenosine
3'-O-tert-Butyldimethylsilyl-2'-deoxyadenosine is a valuable reagent widely used in biomedical research, primarily utilized in the synthesis of nucleosides and nucleotides for studying DNA and RNA structures. Additionally, it finding application in drug design and discovery, targeting diseases such as cancer, viral infections is and genetic disorders. Group: Pharmaceutical. Alternative Names: 3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine; Adenosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-; ((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-2-yl)methanol; 2'-Deoxy-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine; 3'-O-TBDMS-2'-deoxyadenosine. CAS No. 51549-31-6. Pack Sizes: 1 g. Product ID: B1370-339189. Molecular formula: C16H27N5O3Si. Mole weight: 365.5. Custom synthesis is available. Send your inquiries for more information.
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4'-Cyanouridine
Utilizing the crucial factors of "perplexity" and "burstiness," 4'-Cyanouridine, a modified nucleoside, displays promise as an antitumor agent. Its selective enhancement of cytotoxicity against cancer cells and heightened binding affinity to the designated enzyme further solidify its potential in the realm of cancer chemotherapy strategies. Group: Pharmaceutical. Alternative Names: uridine, 4'-C-cyano-; (2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. CAS No. 232589-05-8. Pack Sizes: 5 mg. Product ID: B2706-339130. Molecular formula: C10H11N3O6. Mole weight: 269.21. Custom synthesis is available. Send your inquiries for more information.
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4'-O-Isobutyroylpeguangxienin
A novel nucleoside analogue, 4'-O-Isobutyroylpeguangxienin, is frequently utilized as an antiviral therapeutic agent. Its virucidal activity spans a wide variety of RNA viruses comprising influenza, HIV, and HCV. The drug's mode of action impedes viral RNA synthesis and restrains the virus from replicating, indicating its potential inhibition of viral proliferation. Group: Pharmaceutical. CAS No. 2188162-95-8. Pack Sizes: 5 mg. Product ID: NP1007. Molecular formula: C23H26O7. Mole weight: 414.45. Custom synthesis is available. Send your inquiries for more information.
An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Group: Pharmaceutical. Alternative Names: 4-thiouridine triphosphate (triethylammonium salt form). Pack Sizes: 1 mg. Product ID: B1331-007259. Molecular formula: C9H15N2O14P3S.C6H15N. Mole weight: 500.207 (free acid). Custom synthesis is available. Send your inquiries for more information.
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5'-Amino-2',5'-dideoxyuridine
5'-Amino-2',5'-dideoxyuridine is an imperative nucleoside analogue of significant relevance in the biomedical sector is effectively harnessed for addressing the ubiquitous viral diseases encompassing herpes and HIV. Distinguished by its remarkable characteristic, this compound effectively obstructs the progression of viral DNA synthesis through its adeptness at terminating replication chains. Moreover, its commendable antiviral attributes render it a promising candidate in the realm of therapeutic agent advancement, effectively countering the virulent onslaught of diverse viral infections. Group: Pharmaceutical. Alternative Names: Uridine, 5'-amino-2',5'-dideoxy-; 5'-NH2-2'-dU; 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione. CAS No. 35959-38-7. Pack Sizes: 25 mg. Product ID: B1370-337948. Molecular formula: C9H13N3O4. Mole weight: 227.22. Custom synthesis is available. Send your inquiries for more information.
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5-Aminoallyl-dU CEP
5-Aminoallyl-dU CEP is an essential component in the biomedical sector, extensively utilized for the research and development of modified nucleoside analogs, thus possessing distinctive utilities in the realm of medical investigation. Its significance prevails in the development of therapeutics intended to combat a myriad of ailments encompassing cancer, viral infections and neurodegenerative disorders. Group: Pharmaceutical. Alternative Names: 5-TFA-aminoallyl-dU Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propen-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-[(trifluoroacetyl)amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. CAS No. 144253-90-7. Pack Sizes: 250 mg. Product ID: B1370-339002. Molecular formula: C44H51F3N5O9P. Mole weight: 881.87. Custom synthesis is available. Send your inquiries for more information.
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5-carbamoylmethyluridine
It is a modified nucleoside, and a putative cancer biomarker. Group: Pharmaceutical. Alternative Names: 5-Uridine acetamide; Uridine, 5-(2-amino-2-oxoethyl)-; 5-Carbamoylmethyl Uridine; 5-Uridinacetamide; 5-(2-Amino-2-oxoethyl)uridine; 2-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide; 2-(2,4-dioxo-1-β-D-ribofuranosyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-acetamide. CAS No. 29569-30-0. Pack Sizes: 10 mg. Product ID: B2706-339154. Molecular formula: C11H15N3O7. Mole weight: 301.26. Custom synthesis is available. Send your inquiries for more information.
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5-carboxymethyluridine
5-Uridineacetic Acid is a uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA). Group: Pharmaceutical. Alternative Names: Uridine-5-acetic acid; 5-(Carbonyl)methyluridine; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-b-D-ribofuranosyl-; 5-(carboxymethyl)uridine; 5-Uridineacetic Acid; 1-(beta-D-ribofuranosyl)-5-(carboxymethyl)uracil; 2-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid. CAS No. 20964-06-1. Pack Sizes: 10 mg. Product ID: B2706-253448. Molecular formula: C11H14N2O8. Mole weight: 302.24. Custom synthesis is available. Send your inquiries for more information.
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5-Fluoro-2'-deoxyuridine-5'-triphosphate (triethylammonium salt form)
An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Group: Pharmaceutical. Alternative Names: FdUTP (triethylammonium salt form). CAS No. 1621676-99-0. Pack Sizes: 1 mg. Product ID: B1331-007255. Molecular formula: C9H14N2O14P3F.C6H15N. Mole weight: 486.135 (free acid). Custom synthesis is available. Send your inquiries for more information.
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5-Hydroxymethyl-2'-deoxyuridine
5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine;5116-24-5;alpha-Hydroxythymidine;5-Hydroxymethyldeoxyuridine;2'-Deoxy-5-(hydroxymethyl)uridine;HMdU;5-HMdU;alpha-Hydroxy-thymidin;Thymidine, alpha-hydroxy-;CHEBI:61288;Uridine, 2'-deoxy-5-(hydroxymethyl)-;2'-Deoxy-5-hydroxymethyluridine;5-Hydroxymethyl-deoxyuridine;EJZ33W33JN;1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-. CAS No. 5116-24-5. Pack Sizes: 1 g. Product ID: B1370-120698. Molecular formula: C14H11N5O2S. Mole weight: 313.34. Custom synthesis is available. Send your inquiries for more information.
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5-Hydroxymethyldeoxycytidylic acid
5-Hydroxymethyldeoxycytidylic acid, an indispensable component in the realm of biomedicine, stands as a compound of paramount importance. Renowned for its potential therapeutic value, this nucleoside analog assumes a pivotal role in combatting DNA-related ailments, encompassing malignant neoplasms and pervasive viral afflictions. Researchers earnestly employ this organic entity to unravel the intricate intricacies of DNA structure-function associations and genetic manipulation techniques. Group: Pharmaceutical. Alternative Names: 5-Hmdcyt; 5-Hydroxymethyldeoxycytidylate; 2'-deoxy-5-(hydroxymethyl)cytidine 5'-(dihydrogen phosphate). CAS No. 13009-95-5. Pack Sizes: 10 mg. Product ID: B1370-268030. Molecular formula: C10H16N3O8P. Mole weight: 337.22. Custom synthesis is available. Send your inquiries for more information.
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5-Hydroxyuridine
5-Hydroxyuridine is an anticancer agent. 5-Hydroxyuridine is a modified nucleoside derived from uridine, commonly found in RNA molecules, especially in transfer RNA (tRNA), where it plays a significant role in RNA structure and function. Group: Pharmaceutical. Alternative Names: Uridine, 5-hydroxy-; 1-(beta-D-ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione; 1-β-D-Ribofuranosylisobarbituric acid; Isobarbituridine. CAS No. 957-77-7. Pack Sizes: 1 g. Product ID: B1370-080144. Molecular formula: C9H12N2O7. Mole weight: 260.2. Custom synthesis is available. Send your inquiries for more information.
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5-Methoxycarbonylmethyl-2-thiouridine
5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria. Group: Pharmaceutical. Alternative Names: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester; 5-(Methoxycarbonylmethyl)-2-thiouridine; 5-(2-methoxy-2-oxoethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-(2-methoxy-2-oxoethyl)2-thiouridine. CAS No. 20299-15-4. Pack Sizes: 25 mg. Product ID: B1370-292000. Molecular formula: C12H16N2O7S. Mole weight: 332.33. Custom synthesis is available. Send your inquiries for more information.
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5-Methoxycarbonylmethyluridine
5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker's Yeast. Group: Pharmaceutical. Alternative Names: 5-(Methoxycarbonyl)methyluridine (MCM5U); Uridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic acid methyl ester; 5-(2-methoxy-2-oxoethyl)uridine; 5-Mcmu; Methyl 2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate. CAS No. 29428-50-0. Pack Sizes: 100 mg. Product ID: B2706-292002. Molecular formula: C12H16N2O8. Mole weight: 316.26. Custom synthesis is available. Send your inquiries for more information.
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5-methyldihydrouridine
5-methyldihydrouridine is a modified nucleoside used in RNA to enhance reading frame maintenance in protein synthesis. It has potential therapeutic applications in treating viral infections and neurological disorders such as Parkinson's disease. Group: Pharmaceutical. Alternative Names: 5-Methyl-5,6-dihydrouridine; Hydrouracil, 5-methyl-1-b-D-ribofuranosyl-; 5,6-Dihydro-5-methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyldihydropyrimidine-2,4(1H,3H)-dione. CAS No. 23067-10-9. Pack Sizes: 10 mg. Product ID: B1370-038122. Molecular formula: C10H16N2O6. Mole weight: 260.24. Custom synthesis is available. Send your inquiries for more information.
5'-O-(4,4'-Dimethoxytrityl)-3-formylindole-2'-deoxyriboside is a valuable compound widely used in the biomedical industry serving as a crucial building block in the research and development of nucleoside analogs and can be utilized in drug development against various diseases, including cancers and viral infections. Group: Pharmaceutical. Alternative Names: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde; 1-[5-O-(4,4'-Dimethoxytrityl)-2-deoxy-beta-D-erythro-pentofuranosyl]-1H-indole-3-carbaldehyde. CAS No. 460355-04-8. Pack Sizes: 100 mg. Product ID: B1370-084707. Molecular formula: C35H33NO6. Mole weight: 563.64. Custom synthesis is available. Send your inquiries for more information.
5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology. Group: Pharmaceutical. Alternative Names: N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite; dA(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-adenosine 3'-[2-cyanoethyl N,?N-Bis(1-methylethyl)?phosphoramidite]; DMT-dA(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. CAS No. 98796-53-3. Pack Sizes: 5 g. Product ID: B2706-101370. Molecular formula: C47H52N7O7P. Mole weight: 857.93. Custom synthesis is available. Send your inquiries for more information.
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5'-O-DMT-uridine
It is used for nucleoside modification and RNA synthesis. Group: Pharmaceutical. Alternative Names: 5'-DMT Uridine; 5'-O-DMT uridine; 5'-O-(4,4'-Dimethyltrityl)uridine; 5'-O-DMT-D-uridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 81246-79-9. Pack Sizes: 100 g. Product ID: B2706-098866. Molecular formula: C30H30N2O8. Mole weight: 546.57. Custom synthesis is available. Send your inquiries for more information.
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5-Vinyl-2'-deoxyuridine
5-Vinyl-2'-deoxyuridine (5-VdU) is a nucleoside analogue used in anti-cancer and antiviral therapies. It incorporates into viral DNA and RNA, inhibiting replication. It also confers radiosensitization to cancer cells, enhancing the efficacy of radiation therapy. Group: Pharmaceutical. Alternative Names: 5-vinyldeoxyuridine; 2'-Deoxy-5-vinyluridine; Uridine, 2'-deoxy-5-vinyl-; 5-VdU. CAS No. 55520-67-7. Pack Sizes: 50 mg. Product ID: B1370-004349. Molecular formula: C11H14N2O5. Mole weight: 254.24. Custom synthesis is available. Send your inquiries for more information.
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5-Vinyl-uridine
5-Vinyl-uridine is an innovative biomedical asset, exhibiting remarkable potential for research of diverse viral afflictions encompassing hepatitis C and influenza. Esteemed for its profound antiviral attributes, this formidable nucleoside analogue effectively hinders viral replication via intricate interference in theenhancement of viral RNA. Consequently, it successfully thwarts the exponential proliferation and dissemination of the virus throughout the entire physiological framework. Group: Pharmaceutical. Alternative Names: 5-Ethenyl-uridine; 5-VU. CAS No. 55520-64-4. Pack Sizes: 25 mg. Product ID: B1370-004350. Molecular formula: C11H14N2O6. Mole weight: 270.24. Custom synthesis is available. Send your inquiries for more information.
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6-Aza-2-thiothymine
6-Aza-2-thiothymine, a nucleoside analog widely utilized in cancer research, is profoundly effective in inhibiting thymidylate synthase; hence, it's active against several cancer cell lines. Furthermore, the compound's promising potential as a radiosensitizer renders it an excellent option for the management of solid tumors. This ground-breaking analog with unparalleled efficacy and versatility is a definitive focal point of modern-day cancer research. Group: Pharmaceutical. Alternative Names: 2-Thio-6-azathymine; 6-Azathiothymine; 6-Methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one; 3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one; 6-Methyl-3-thioxo-3,4-dihydro-2H-[1,2,4]triazin-5-one; 1,2,4-Triazin-5(2H)-one, 3,4-dihydro-6-methyl-3-thioxo-; NSC 1609; NSC 38618; 3-Mercapto-6-methyl-as-triazin-5-ol; NSC 102906; 3,4-Dihydro-6-methyl-3-thioxo-1,2,4-triazin-5(2H)-one; 6-Methyl-3-thio-as-triazine-3,5(2H,4H)-dione. CAS No. 615-76-9. Pack Sizes: 25 g. Product ID: B2699-030048. Molecular formula: C4H5N3OS. Mole weight: 143.17. Custom synthesis is available. Send your inquiries for more information.
6-(b-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one, a versatile drug boasting both antiviral and antitumor properties, has become an invaluable instrument in the medicinal world. Through its DNA synthesis interference, it displays its prowess in staving off viruses and cancerous cells alike, thereby serving as a beacon of hope for those stricken with HIV, leukemia, and solid tumors. Notable for its unique structure and mode of operation, this remarkable molecule has cemented its reputation as a priceless commodity in the realm of biomedical research. Group: Pharmaceutical. Alternative Names: 6-(2-Deoxy-β-D-erythro-pentofuranosyl)-4,6-dihydro-1H-pyrimido[4,5-c][1,2]oxazin-7(3H)-one; 6-(β-D-2'-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one; dP; P-2'-Deoxyribose; P-Nucleoside (dP); 6-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,6-dihydro-3H-pyrimido[4,5-c][1,2]oxazin-7(8H)-one; Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one. CAS No. 126128-42-5. Pack Sizes: 50 mg. Product ID: B1370-047847. Molecular formula: C11H15N3O5. Mole weight: 269.25. Custom synthesis is available. Send your inquiries for more information.
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6-Thio-dG
6-thio-dG is a nucleoside analog and telomerase substrate. Uses: Studies suggest that beta-tgdr is a latent form of tg. since resistance to antileukemic agent 6-thioguanine inevitably develops in animal tumors, this new agent beta-tgdr is of potential clinical use. Group: Pharmaceutical. Alternative Names: 6-Thio-2'-Deoxyguanosine; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine; 2'-Deoxythioguanosine; 2'-Desoxy-6-thioguanosine; NSC 71261; TGdR; Thioguanine Deoxyriboside; β-Thioguanine Deoxyriboside. CAS No. 789-61-7. Pack Sizes: 50 mg. Product ID: B1370-207604. Molecular formula: C10H13N5O3S. Mole weight: 283.31. Custom synthesis is available. Send your inquiries for more information.
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6-Thioguanosine
6-Thioguanosine is a significant nucleoside analog employed in the biomedical industry, holding an eminent role in comprehending the intricate ramifications of DNA methylation on gene expression. Group: Pharmaceutical. Alternative Names: 2-Amino-6-mercapto-9-(b-D-ribofuranosyl)purine; 6-Mercaptoguanosine; (-)-2-Amino-6-mercaptopurine riboside. CAS No. 85-31-4. Pack Sizes: 1 g. Product ID: B2706-078431. Molecular formula: C10H13N5O4S. Mole weight: 299.31. Custom synthesis is available. Send your inquiries for more information.
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7-Deaza-2'-deoxy-7-iodoguanosine
7-Deaza-2'-deoxy-7-iodoguanosine is a potent antiviral compound used in biomedicine. It exhibits antiviral activity against Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV). This nucleoside analogue acts by inhibiting viral DNA synthesis, making it effective in the treatment of HSV and VZV infections. It is commonly used in research and drug development related to antiviral therapies. Group: Pharmaceutical. Alternative Names: 2-Amino-7-(2-deoxy-b-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one; 7-Deaza-7-iodo-2'-deoxyguanosine; 2-Amino-7-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one; 7-iodo-7-deaza-2'-deoxyguanosine; 7-Iodo-2'-deoxy-7-carbaguanosine; 2-Amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one. CAS No. 172163-62-1. Pack Sizes: 250 mg. Product ID: B0001-306406. Molecular formula: C11H13IN4O4. Mole weight: 392.15. Custom synthesis is available. Send your inquiries for more information.
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7-Deaza-2'-deoxyadenosine
It is a purine nucleoside phosphorylase inhibitor. Group: Pharmaceutical. Alternative Names: 4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-Deoxytubercidin; Deoxytubercidin; 7-Deazadeoxyadenosine; (2R,3S,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-deoxy-7-deazaadenosine. CAS No. 60129-59-1. Pack Sizes: 250 mg. Product ID: B2706-039342. Molecular formula: C11H14N4O3. Mole weight: 250.25. Custom synthesis is available. Send your inquiries for more information.
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7-Methyl-3'-O-methylguanosine 5'-(trihydrogen diphosphate), inner salt, TEA salt
7-Methyl-3'-O-methylguanosine 5'-(trihydrogen diphosphate), inner salt, TEA salt is a modified nucleoside used in research. It consists of guanosine with methyl groups at the 7th position of the base and the 3' carbon of the ribose sugar. It has a diphosphate group at the 5' carbon of the ribose with three hydrogen atoms bound to the phosphates. It is commonly employed in biochemical studies, especially in RNA research. Group: Pharmaceutical. Alternative Names: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-3'-O-methyl-, inner salt, compd. with N,N-diethylethanamine (1:x); Triethylamine ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-3,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl diphosphate (1:x); 3'-OMe-m7GDP TEA Salt; Guanosine 5'-(trihydrogen diphosphate), 7-Methyl-3'-O-Methyl-, inner Salt, compd. with N,N-diethylethanamine. CAS No. 2089461-52-7. Pack Sizes: 100 mg. Product ID: B1370-088411. Molecular formula: C12H19N5O11P2.xC6H15N. Mole weight: 471.26 (free base). Custom synthesis is available. Send your inquiries for more information.
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8-Azanebularine CE-Phosphoramidite
DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite is a chemical compound used in oligonucleotide synthesis. It protects the 5'-hydroxyl group with a DMTr group and stabilizes the ribose sugar with a 2'-O-TBDMS modification. Additionally, it incorporates 8-azanebularine as a modified nucleoside. The 3'-CE phosphoramidite facilitates nucleotide addition during synthesis. This compound allows for the controlled synthesis of oligonucleotides with specific modifications, important for various applications in molecular biology and biotechnology. Group: Pharmaceutical. Alternative Names: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite. CAS No. 771494-03-2. Pack Sizes: 50 mg. Product ID: B1370-087581. Molecular formula: C45H60N7O7PSi. Mole weight: 870.08. Custom synthesis is available. Send your inquiries for more information.
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8-Iodo-guanosine
8-Iodo-guanosine, a chemical compound used in biomedical research, has proven instrumental in studying the impacts of purine nucleoside analogs on cancers and viral infections. As an iodine-substituted guanosine derivative, it exhibits the potential to act as an inhibitor of RNA viruses like HIV and hepatitis C. Group: Pharmaceutical. Alternative Names: 8-Iodoguanosine; 8-I-rG; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-iodo-1H-purin-6(9H)-one; 8-Iodocoumarin; NSC 79218. CAS No. 18438-99-8. Pack Sizes: 1 g. Product ID: B1370-004370. Molecular formula: C10H12IN5O5. Mole weight: 409.14. Custom synthesis is available. Send your inquiries for more information.
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AB-729
AB-729 is a nucleoside analogue that acts as an RNA interference (RNAi) and can inhibit viral replication, reducing HBV antigens. AB-729 binds to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes entry into hepatocytes through asialoglycoprotein receptor (ASGR). Group: Pharmaceutical. Alternative Names: AB-729|HY-132603. CAS No. 2634739-74-3. Pack Sizes: 1mg;1g;10g. Product ID: 2634739-74-3. Custom synthesis is available. Send your inquiries for more information.
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Abacavir
Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Group: Pharmaceutical. Alternative Names: Ziagen. CAS No. 136470-78-5. Pack Sizes: 1mg;1g;10g. Product ID: 136470-78-5. Molecular formula: C14H18N6O. Mole weight: 286.33. Custom synthesis is available. Send your inquiries for more information.
Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Molecular formula: C33H46N6O10. Mole weight: 686.75. Custom synthesis is available. Send your inquiries for more information.
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Abacavir 5'-β-D-Glucuronide
Abacavir 5'-β-D-Glucuronide is a metabolite of Abacavir, which is a nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Group: Pharmaceutical. Alternative Names: [(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl]methyl β-D-glucopyranosiduronic acid; Abacavir 5'-Glucuronide. CAS No. 384329-76-4. Pack Sizes: 1mg;1g;10g. Product ID: 384329-76-4. Molecular formula: C20H26N6O7. Mole weight: 462.46. Custom synthesis is available. Send your inquiries for more information.
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Abacavir EP Impurity B
Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Pharmaceutical. Alternative Names: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine; O-Pyrimidine derivative abacavir. CAS No. 1443421-69-9. Pack Sizes: 1mg;1g;10g. Product ID: 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88. Custom synthesis is available. Send your inquiries for more information.
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Abacavir Sulfate (2:1)
Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. Abacavir is an analog of guanosine (a purine). Its target is the viral reverse transcriptase enzyme. Group: Pharmaceutical. Alternative Names: 1592U89. CAS No. 188062-50-2. Pack Sizes: 1mg;1g;10g. Product ID: 188062-50-2. Molecular formula: C14H18N6O.1/2H2O4S. Mole weight: 335.35. Custom synthesis is available. Send your inquiries for more information.
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ABT-072
ABT-072 is a potent and orally active non-nucleoside HCV NS5B polymerase inhibitor with EC50s of 1 nM and 0.3 nM for HCV GT1a and HCV GT1b, respectively. Group: Pharmaceutical. Alternative Names: (E)-N-(4-(3-(tert-Butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide; Methanesulfonamide, N-[4-[(1E)-2-[5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-(1,1-dimethylethyl)-2-methoxyphenyl]ethenyl]phenyl]-; N-(4-{(E)-2-[5-(2,4-Dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2-methoxy-3-(2-methyl-2-propanyl)phenyl]vinyl}phenyl)methanesulfonamide. CAS No. 1132936-00-5. Pack Sizes: 1mg;1g;10g. Product ID: 1132936-00-5. Molecular formula: C24H27N3O5S. Mole weight: 469.55. Custom synthesis is available. Send your inquiries for more information.
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ABT-072 potassium trihydrate
ABT-072 potassium trihydrate is a potent and orally active non-nucleoside HCV NS5B polymerase inhibitor with EC50s of 1 nM and 0.3 nM for HCV GT1a and HCV GT1b, respectively. Group: Pharmaceutical. Alternative Names: Methanesulfonamide, N-(4-((1E)-2-(5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-(1,1-dimethylethyl)-2-methoxyphenyl)ethenyl)phenyl)-, potassium salt, hydrate (1:1:3); (E)-N-(4-(3-(tert-Butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide potassium salt trihydrate. CAS No. 1132940-31-8. Pack Sizes: 1mg;1g;10g. Product ID: 1132940-31-8. Molecular formula: C24H32KN3O8S. Mole weight: 561.69. Custom synthesis is available. Send your inquiries for more information.
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ABT 702
ABT 702 is a non-nucleoside adenosine kinase (ADK) inhibitor (IC50 = 2 nM and 50 nM in cytosolic and intact cell assays, respectively). Study conformed that ABT702 could reduce pain and inflammation in animal models, yet be clastogenic in an in vitro Chinese Hamster micronucleus assay. Group: Pharmaceutical. Alternative Names: ABT 702; ABT702; ABT-702; 5-(3-bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine. CAS No. 214697-26-4. Pack Sizes: 1mg;1g;10g. Product ID: 214697-26-4. Molecular formula: C22H19BrN6O. Mole weight: 463.33. Custom synthesis is available. Send your inquiries for more information.
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ABT 702 Dihydrochloride
ABT 702 Dihydrochloride is a potent and selective non-nucleoside adenosine kinase inhibitor with IC50 value of 1.7 nM. ABT 702 displays oral activity in animal models of pain and inflammation. In Mar 2005, ABT 702 was discontinued preclinical for Pain and Rheumatoid arthritis in USA. Uses: Anti-inflammation. Group: Pharmaceutical. Alternative Names: ABT702 Dihydrochloride; ABT-702 Dihydrochloride. CAS No. 1188890-28-9. Pack Sizes: 50 mg. Product ID: B2693-475131. Molecular formula: C22H21BrCl2N6O. Mole weight: 536.26. Custom synthesis is available. Send your inquiries for more information.
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Acyclovir
Aciclovir is a synthetic nucleoside analogue active against herpesviruses. It is primarily used for the treatment of herpes simplex virus infections, chickenpox and shingles. Group: Pharmaceutical. Alternative Names: Valaciclovir Impurity B; Valaciclovir hydrochloride EP Impurity B; Valaciclovir hydrochloride hydrate EP Impurity B; Valaciclovir EP Impurity B; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one; 2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one; 2-Amino-9-(2-hydroxy-ethoxymethyl)-3,9-dihydro-purin-6-one; 2-Amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one; 2-Amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one; 2-Amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol; 9-(2-Hydroxyethoxymethyl)guanine; Acicloftal; Aciclovir; Acivir; ACV; Acyclo V; Acycloguanosine; Avirase; Axiluowei; Cargosil; Gerpevir; Herpevir; Lovir; Novirus; NSC 645011; Poviral; Rouz-Aciclovir; Vicclox; Vipral; Virax; Virless; Virorax; Virovir; Wellcome 248U; Zirax; Zovirax; Zyclir. CAS No. 59277-89-3. Pack Sizes: 25 g. Product ID: BBF-04163. Molecular formula: C8H11N5O3. Mole weight: 225.2. Custom synthesis is available. Send your inquiries for more information.
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AT-265
AT-265 is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity. Group: Pharmaceutical. Alternative Names: 5'-Sulfamoyl-2-chloroadenosine; 2-chloro-5'-o-sulfamoyladenosine; Antibiotic AT 265. CAS No. 66522-52-9. Pack Sizes: 5 mg. Product ID: BBF-03211. Molecular formula: C10H13ClN6O6S. Mole weight: 380.77. Custom synthesis is available. Send your inquiries for more information.
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