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| Product | Description | |
|---|---|---|
| Norepinephrine Impurities | Norepinephrine Impurities play a crucial role in the pharmaceutical industry, primarily in the quality control and characterization of norepinephrine formulations. These impurities are vital for ensuring the safety and efficacy of medications used in treating conditions like hypotension, cardiac arrest, and depression by facilitating thorough drug substance analysis and stability testing. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 4'-Hydroxy Atomoxetine | 4'-Hydroxyatomoxetine is an impurity of Atomoxetine, a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Uses: A metabolite of atomoxetine, a norepinephrine uptake blocker. Group: Pharmaceutical. CAS No. 435293-66-6. Pack Sizes: 10 mg. Product ID: B2694-120067. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 32390A | A 32390A is an antibiotic produced by Pyrenochaeta sp. (NRRL-5786). It has anti-gram-positive bacteria and fungi activity. It also inhibits the activity of dopamine tetra-hydroxylase, can reduce the level of norepinephrine in the heart and adrenal glands, and has a hypotensive effect on hypertensive rats. Group: Pharmaceutical. CAS No. 61241-59-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03140. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ansofaxine hydrochloride | Ansofaxine hydrochloride is a triple reuptake inhibitor of serotonin (IC50 = 723 nM), dopamine (IC50 = 491 nM) and norepinephrine (IC50 = 763 nM). Group: Pharmaceutical. CAS No. 916918-84-8. Pack Sizes: 100 mg. Product ID: B1370-007613. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dasotraline hydrochloride | Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Group: Pharmaceutical. CAS No. 675126-08-6. Pack Sizes: 5 mg. Product ID: B0084-241506. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desvenlafaxine | Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. Uses: Antidepressive agents; neurotransmitter uptake inhibitors. Group: Pharmaceutical. CAS No. 93413-62-8. Pack Sizes: 250 mg. Product ID: B0084-100763. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Desvenlafaxine (O-Desmethyl Venlafaxine) Succinate Monohydrate | Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively. Group: Pharmaceutical. CAS No. 386750-22-7. Pack Sizes: 5 g. Product ID: B2693-067733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Droxidopa | Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). It is capable of crossing the protective blood-brain barrier. Group: Pharmaceutical. CAS No. 23651-95-8. Pack Sizes: 500 mg. Product ID: B0046-063644. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Escitalopram | Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. Uses: Serotonin uptake inhibitors; antidepressive agents, second-generation. Group: Pharmaceutical. CAS No. 128196-01-0. Pack Sizes: 500 mg. Product ID: B2693-461840. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Levomilnacipran Hydrochloride | Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Forest Laboratories and Pierre Fabre Group, and was approved by the Food and Drug Administration in July 2013. Levomilnacipran is the levo-enantiomer of milnacipran, and has similar effects and pharmacology, acting as a serotonin-norepinephrine reuptake inhibitor (SNRI). Uses: Antidepressive agents. Group: Pharmaceutical. CAS No. 175131-60-9. Pack Sizes: 200 mg. Product ID: B0084-263048. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milnacipran-[d5] hydrochloride | Milnacipran-[d5] hydrochloride is a labelled impurity of Milnacipran. Milnaciprana is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat fibromyalgia. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014880. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester | Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists. Group: Pharmaceutical. CAS No. 286961-14-6. Pack Sizes: 100 g. Product ID: BB019917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nepicastat HCl | Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine/noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine/noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Group: Pharmaceutical. CAS No. 170151-24-3. Pack Sizes: 50 mg. Product ID: B0084-453616. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Methyl-3,3-Diphenylpropylamine | N-Methyl-3,3-Diphenylpropylamine is an intriguing molecule that exhibits remarkable effects on the central nervous system, acting as a highly potent stimulant. Its usage in research has proven valuable in understanding the transport and regulatory mechanisms of dopamine and norepinephrine. Moreover, its therapeutic potential in addressing complex neurological disorders such as attention deficit hyperactivity disorder and narcolepsy bears considerable promise. Group: Pharmaceutical. CAS No. 28075-29-8. Pack Sizes: 10 g. Product ID: B2699-089274. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Methyl Duloxetine | An impurity of duloxetine, a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Group: Pharmaceutical. CAS No. 132335-46-7. Pack Sizes: 50 mg. Product ID: B2694-083191. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N,N-Dimethyl-L-Tyrosine | N,N-Dimethyl-L-Tyrosine, a derivative of the amino acid tyrosine, has been a subject of interest in the research field due to its key role in elucidating amino acid metabolism. Additionally, it has been extensively studied for its precursor role in the synthesis of well-known neurotransmitters like dopamine and norepinephrine, thereby finding novel therapeutic applications in the treatment of neurodegenerative disorders such as Parkinson's disease and depression. The significance of this chemical compound could not be overstated in the realm of medicinal research. Group: Pharmaceutical. CAS No. 17350-74-2. Pack Sizes: 50 mg. Product ID: B2699-052153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Noradrenalone Hydrochloride | An impurity of Norepinephrine. Norepinephrine, also known as noradrenaline, is a marker for catecholamine-secreting tumors such as pheochromocytoma, paraganglioma, and neuroblastoma. Group: Pharmaceutical. CAS No. 5090-29-9. Pack Sizes: 1 g. Product ID: B1370-471058. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| O-Desmethyl Venlafaxine Cyclic Impurity | O-Desmethyl Venlafaxine Cyclic Impurity is a cyclic impurity of O-Desmethylvenlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Group: Pharmaceutical. CAS No. 1346601-55-5. Pack Sizes: 10 mg. Product ID: B2694-485086. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Reboxetine Mesylate | Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM. Group: Pharmaceutical. CAS No. 98769-84-7. Pack Sizes: 500 mg. Product ID: B2694-158042. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-Viloxazine Hydrochloride | The R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) used as an antidepressant. Uses: The (r)-isomer of. Group: Pharmaceutical. CAS No. 56287-63-9. Pack Sizes: 1 g. Product ID: B2694-122078. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Viloxazine Hydrochloride | The S-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) used as an antidepressant. Uses: The (s)-isomer of. Group: Pharmaceutical. CAS No. 56287-61-7. Pack Sizes: 1 g. Product ID: B2694-122081. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Venlafaxine | Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as the treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It has seemingly superior efficacy in severe depression as a narcotic and is increasingly used as a measure of last resort for refractory cases. Group: Pharmaceutical. CAS No. 93413-69-5. Pack Sizes: 500 mg. Product ID: NP3405. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Venlafaxine-[d10] Hydrochloride | One of the isotopic labelled form of Venlafaxine HCl, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Group: Pharmaceutical. CAS No. 1216539-56-8. Pack Sizes: 1 mg. Product ID: BLP-013099. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Venlafaxine EP Impurity A hydrochloride | Venlafaxine EP Impurity A hydrochloride is an impurity of Venlafaxine, which is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. Group: Pharmaceutical. CAS No. 50822-98-5. Pack Sizes: 100 mg. Product ID: B2694-485083. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Venlafaxine hydrochloride | Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. Uses: Antidepressant. Group: Pharmaceutical. CAS No. 99300-78-4. Pack Sizes: 10 g. Product ID: NP3427. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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