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| Product | Description | |
|---|---|---|
| 4,4'-DIHYDROXY-2-METHOXYCHALCONE | Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. It was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Group: Pharmaceutical. Alternative Names: (E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; (E)-4,4'-Dihydroxy-2-methoxychalcone; 4,4'-Dihydroxy-2-methoxy-trans-chalcone; 4'-Dihydroxy-2-Methoxychalcone; Retrochalcone. CAS No. 34221-41-5. Pack Sizes: 10 mg. Product ID: NP0936. Molecular formula: C16H14O4. Mole weight: 270.28. Custom synthesis is available. Send your inquiries for more information. |  London |
| Aristololactam BII | Aristolactam BII, a natural alkaloid isolated from the herbs of Aristolochia debilis Sieb. et Zucc exhibits significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system. By directly inhibiting the production of nitric oxide, aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells. Uses: Anti-syncytium. Group: Pharmaceutical. Alternative Names: Cepharanone B. CAS No. 53948-09-7. Pack Sizes: 1 mg. Product ID: NP0328. Molecular formula: C17H13NO3. Mole weight: 279.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Chrysoeriol | Chrysoeriol is a natural compound isolated from the herbs of Medicago sativa. Chrysoeriol can potently inhibit the induction of nitric oxide synthase by blocking activator protein 1 (AP-1) activation and its anti-inflammatory effects. Chrysoeriol can induce nod genes in rhizobium meliloti. Chrysoeriol can inhibit the downstream signal transduction pathways of platelet-derived growth factor (PDGF)-Rbeta, including ERK1/2, p38, and Akt phosphorylation, which suggests that chrysoeriol may be used for the prevention and treatment of vascular diseases during restenosis after coronary angioplasty. Group: Pharmaceutical. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether; Scoparol; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-. CAS No. 491-71-4. Pack Sizes: 25 mg. Product ID: NP2023. Molecular formula: C16H12O6. Mole weight: 300.27. Custom synthesis is available. Send your inquiries for more information. | London |
| DAF-2 | DAF-2 is a fluorescent indicator for the detection of nitric oxide (NO). Group: Pharmaceutical. Alternative Names: DAF-2-CAS 205391-01-1-Calbiochem;4,5-Diaminofluorescein; 2-(3,6-dihydroxy-4,5-diamino-9H-xanthen-9-yl)-benzoic acid. CAS No. 205391-01-1. Pack Sizes: 1 mg. Product ID: B2708-173876. Molecular formula: C20H14N2O5. Mole weight: 362.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Echinacoside | Echinacoside, a natural polyphenolic compound, has various kinds of pharmacological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Group: Pharmaceutical. Alternative Names: 2-(3,4-Dihydroxyphenyl)ethyl 4-(3-(3,4-dihydroxyphenyl)-2-propenoate)-3-O-(b-D-glucopyranose)-6-O-(a-L-rhamnopyranose)-b-D-glucopyranoside. CAS No. 82854-37-3. Pack Sizes: 25 mg. Product ID: NP5238. Molecular formula: C35H46O20. Mole weight: 786.74. Custom synthesis is available. Send your inquiries for more information. | London |
| Edonerpic maleate | The maleate salt form of Edonerpic, which is a neuroproptectant. Edonerpic is in clinical trials for the treatment of Alzheimer's disease (AD). It inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor, as well as it may be beneficial for the treatment of neurodegenerative disorders related to oxidative stress, such as Parkinson's disease. Uses: Candidate therapeutic agent for alzheimer's disease. Group: Pharmaceutical. Alternative Names: T-817 maleate; T-817MA; 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol maleate. CAS No. 519187-97-4. Pack Sizes: 10 mg. Product ID: B0084-054035. Molecular formula: C20H25NO6S. Mole weight: 407.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Excisanin B | Excisanin B is extracted from the herbs of Isodon japonicus. It inhibits production of nitric oxide in LPS-induced murine macrophage RAW264.7 cells. Group: Pharmaceutical. Alternative Names: 1alpha,7alpha,14beta-Trihydroxy-12alpha-acetoxykaura-16-ene-15-one. CAS No. 78536-36-4. Pack Sizes: 5 mg. Product ID: NP1397. Molecular formula: C22H32O6. Mole weight: 392.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Harpagoside | Harpagoside, isolated from the Harpagophytum procumbens (Devil's Claw) root or Crophularia ningpoensis Hemsl (Figwort), inhibited lipopolysaccharide-induced mRNA levels. Harpagoside also inhibited protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells, which involves suppression of NF-kappaB activation, thereby inhibiting downstream inflammation and subsequent pain events. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: [1S-[1alpha,4aalpha,5alpha,7alpha(E),7aalpha]]-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(allyl-1-oxo-3-phenyl)oxy]cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside; Harpogoside; [(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate. CAS No. 19210-12-9. Pack Sizes: 50 mg. Product ID: NP3892. Molecular formula: C24H30O11. Mole weight: 494.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Irigenin | Irigenin is a natural compound isolated from the rhizomes of Belamcanda chinensis (L.) DC. Irigenin prevents metastatic capacity of lung cancer cells by selectively blocking Extra Domain A. Irigenin has anti-inflammatory effects that can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect. Group: Pharmaceutical. Alternative Names: 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one. CAS No. 548-76-5. Pack Sizes: 20 mg. Product ID: NP2498. Molecular formula: C18H16O8. Mole weight: 360.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Isosorbide 2-nitrate | Isosorbide 2-nitrate is a nitric oxide donor with biomedicine applications in research of pharmaceutical formulation to enhance drug delivery. It is also a metabolite of Isosorbide Dinitrate which is an antianginal. Group: Pharmaceutical. Alternative Names: Isosorbide 2-mononitrate; D-Glucitol, 1,4:3,6-dianhydro-, 2-nitrate; 1,4:3,6-Dianhydro-D-glucitol 2-nitrate; 6-Nitrooxyhexahydro-furo[3,2-b]furan-3-ol; Isosorbide Mononitrate Related Compound A (USP). CAS No. 16106-20-0. Pack Sizes: 500 mg. Product ID: B1370-186685. Molecular formula: C6H9NO6. Mole weight: 191.14. Custom synthesis is available. Send your inquiries for more information. | London |
| Isovitexin | Isovitexin, a food phytochemical contained in dietary rice products, or as a natural plant flavonoid isolated from the seeds of Vitex trifolia L, suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages. Isovitexin exhibits anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating HO-1/Nrf2 pathways. Isovitexin can inhibit xanthine oxidase with an IC50 value of 15.2 microM, and it may protect cells from oxidative stress. Group: Pharmaceutical. Alternative Names: Saponaretin; Homovitexin; (1S)-1,5-anhydro-1-[5,7-dihydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol; 4H-1-Benzopyran-4-one, 6-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 6-β-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Flavone, 6-β-D-glucopyranosyl-4',5,7-trihydroxy-; Homovitexin; 6-C-Glucosylapigenin; 6-C-β-D-Glucopyranosylapigenin; Apigenin 6-C-β-D-glucoside; Apigenin 6-C-β-glucopyranoside; Apigenin-6-C-glucoside; Apigenin-6-C-β-D-glucopyranoside; Avroside; Isoavroside; Isovitexin (C-6 isomer); Saponaretin. CAS No. 38953-85-4. Pack Sizes: 100 mg. Product ID: NP1807. Molecular formula: C21H20O10. Mole weight: 432.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Kazinol B | Kazinol B is a natural flavonoid found in the barks of Broussonetia papyrife. It has inhibition of nitric oxide production on LPS-activated macrophages and has inhibiion of SOCE. Group: Pharmaceutical. Alternative Names: (2S)-2',2'-dimethyl-7'-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,2'H-2,6'-bichrom ene-7,8'-diol. CAS No. 99624-27-8. Pack Sizes: 1 mg. Product ID: NP2014. Molecular formula: C25H28O4. Mole weight: 392.5. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Arginine α-ketoglutarate | L-Arginine α-ketoglutarate is a salt form of arginine, which is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Protein supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Arginine oxoglurate; L-Arginine alpha-Ketoglutarate(1:1); (S)-2-Amino-5-guanidinopentanoic acid 2-oxopentanedioic acid (1:1); L-Arginine alpha-ketoglutarate. CAS No. 16856-18-1. Pack Sizes: 100 g. Product ID: B0350-340579. Molecular formula: C11H20N4O7. Mole weight: 320.302. Custom synthesis is available. Send your inquiries for more information. | London |
| Latanoprostene Bunod | Latanoproste bunod is a nitric oxide-donating prostaglandin F2α (FP) receptor agonist. Under the trade name Vyzulta, it has been approved for the treatment of intraocular pressure in patients with open-angle glaucoma or ocular hypertension in 2017. Group: Pharmaceutical. Alternative Names: BOL-303259-X; NCX 116; PF-3187207. CAS No. 860005-21-6. Pack Sizes: 25 mg. Product ID: B2692-291720. Molecular formula: C27H41NO8. Mole weight: 507.62. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Biopterin | L-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). It is an important cofactor in the production of many essential neurotransmitters, such as dopamine, seratonin and epinephrine, and plays an important role in the production of nitric oxide in the body. It has been shown to be cytotoxic to melanocytes in vitro, and may be a useful noninvasive biomarker. Group: Pharmaceutical. Alternative Names: L-Biopterin; NSC 339699; NSC-339699; NSC339699; AR 1D8544; AR-1D8544; AR1D8544; LS126316; LS-126316; LS 126316; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone; (-)-Biopterin; 6-Biopterin; Biopterin; L-erythro-Biopterin; NSC 339699; Pterin H B2; (1'R,2'S)-Biopterin; L-erythro-6-(1,2-Dihydroxypropyl)pterin. CAS No. 22150-76-1. Pack Sizes: 1 g. Product ID: B0084-467547. Molecular formula: C9H11N5O3. Mole weight: 273.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Luteolin | Luteolin is an anti-inflammatory, antioxidant and free radical scavenger. Luteolin inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. It also inhibits TNF-α-induced COX-2 expression, and phosphodiesterase with with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM for PDE1-5 respectively. It inhibits proliferation of Lewis lung carcinoma cells in vivo. Luteolin is a natural compound found in the leaves of Dracocephalum ruyschiana L. It can be used in cosmetics material. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: 3',4',5,7-Tetrahydroxyflavone; Digitoflavone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; Flacitran. CAS No. 491-70-3. Pack Sizes: 5 g. Product ID: NP1855. Molecular formula: C15H10O6. Mole weight: 286.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Magnesium nitrate hexahydrate | A hygroscopic salt which in air quickly turns into the hexahydrate form. The compound has been employed in the concentration of nitric acid through heating magnesium nitrate hexahydrate yielding magnesium oxide, oxygen, and nitrogen oxides. Uses: Chemical production, analytical chemistry, laboratory synthesis, industrial applications. CAS No. 13446-18-9. |  |
| Magnolol | Magnolol is a bioactive lignin found in Magnolia officinalis and acts as a TNF-α and nitric oxide (NO) inhibitor. It exhibits potential therapeutic effect on anxiety, cough, headache and allergies. Magnolol has antifungal, antibacterial, anti-oxidative, antidepressant-like, anti-tumor, and neuroprotective effects. It can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products. Uses: Anti-oxidative; antimicrobial; antifungal. Group: Pharmaceutical. Alternative Names: 5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol; 5,5'-Diallyl-2,2'-biphenyldiol; 5,5'-Diallyl-2,2'-dihydroxybiphenyl; 2,2'-Bichavicol; 2,2'-Bichavicol; 5,5'-Di-2-propen-1-yl[1,1'-biphenyl]-2,2'-diol; E 100338; NSC 293099. CAS No. 528-43-8. Pack Sizes: 2 g. Product ID: NP4197. Molecular formula: C18H18O2. Mole weight: 266.34. Custom synthesis is available. Send your inquiries for more information. | London |
| methyl 3-guanidino-4-methylbenzoate mononitrate | Methyl 3-guanidino-4-methylbenzoate mononitrate, a highly versatile pharmaceutical intermediate, is utilized for the synthesis of nitric oxide synthase isoform-specific drugs that exhibit therapeutic potential against a variety of cardiovascular and inflammatory maladies associated with NOS isoform dysregulation. Its wide scope of therapeutic applications underscores its immense potential as a drug precursor. Group: Pharmaceutical. Alternative Names: methyl 3-guanidino-4-methylbenzoate nitrate. CAS No. 1025716-99-7. Pack Sizes: 5 g. Product ID: B2699-046503. Molecular formula: C10H14N4O5. Mole weight: 270.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Monotropein | Monotropein, which comes from the root of Morinda officinalis How, was found to inhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages. The anti-inflammatory effects of monotropein are mainly related to the inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. Monotropein also exerted anti-apoptosis and anti-catabolic activity in chondrocytes. Uses: Antinociceptive/anti-inflammatory. Group: Pharmaceutical. Alternative Names: (1S,2S,6S,9R)-9-hydroxy-9-(hydroxymethyl)-2-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,7-diene-5-carboxylic acid; 1α-(β-D-Glucopyranosyloxy)-1,4aα,7,7aα-tetrahydro-7β-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid; Morinda officinalis How. CAS No. 5945-50-6. Pack Sizes: 50 mg. Product ID: B1370-124565. Molecular formula: C16H22O11. Mole weight: 390.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Morachalcone A | Morachalcone A is isolated from the roots of Morus alba. It exhibits potent inhibitory activity on nitric oxide production. Uses: Antioxidant activity; cytotoxic activity. Group: Pharmaceutical. Alternative Names: (2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(2,4-dih ydroxyphenyl)-2-propen-1-one. CAS No. 76472-88-3. Pack Sizes: 1 mg. Product ID: NP0960. Molecular formula: C20H20O5. Mole weight: 340.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Mussaenoside | Mussaenoside is a natural iridoid found in the herbs of Melampyrum roseum Maxim, it can inhibit the release of pro-inflammatory cytokines induced by LPS, the production of nitric oxide (NO) and prostaglandin E2, and the expression of inducible NO synthase and cyclooxygenase-2 induced by lipopolysaccharide (LPS) in the RAW264.7 murine macrophage cell line. Mussaenoside also exhibits the activity of anti-inflammatory. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: (1S,7S)-1-(β-D-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-7-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester. CAS No. 64421-27-8. Pack Sizes: 1 mg. Product ID: NP3859. Molecular formula: C17H26O10. Mole weight: 390.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Myricetin 3-O-galactoside | Myricetin-3-o-galactoside is a natural flavonoid found in the root bark of Myrica cerifera L. Myricetin-3-o-galactoside exhibits antinociceptive and anti-inflammatory activities, which are related to peripheral inhibition of nitric oxide synthesis, mainly. Uses: Antinociceptive,anti-inflammatory. Group: Pharmaceutical. Alternative Names: Myricetin 3-O-beta-galactopyranoside;Myricetin 3-O-β-D-Galactopyranoside; :4H-1-Benzopyran-4-one,3-(b-D-galactopyranosyloxy)-5,7-dihydroxy-2-(3,4,5- trihydroxyphenyl)-;3,3',4',5,5',7-Hexahydroxyflavone-3-b-D-galactopyranoside. CAS No. 15648-86-9. Pack Sizes: 5 mg. Product ID: NP1967. Molecular formula: C21H20O13. Mole weight: 480.38. Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-Nebivolol | Dexnebivolol is an enantiomer of Nebivolol which is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and left ventricular failure in Europe. It is highly cardioselective under certain circumstances. Uses: Treatment of hypertension and left ventricular failure. Group: Pharmaceutical. Alternative Names: R67138; R-67138; R 67138; Dexnebivolol; (S,R,R,R)-nebivolol; Bystolic; D-Nebivolol; (αR,α'R,2R,2'S)-α,α'-[IMinobis(Methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-Methanol]. CAS No. 118457-15-1. Pack Sizes: 5 mg. Product ID: B1370-256091. Molecular formula: C22H25F2NO4. Mole weight: 405.44. Custom synthesis is available. Send your inquiries for more information. | London |
| NITRIC ACID 67% | A inorganic compound with the formula HNO3. It is a highly corrosive mineral acid. The compound is colourless, but older samples tend to be yellow cast due to decomposition into oxides of nitrogen. Most commercially available nitric acid has a concentration of 68% in water. When the solution contains more than 86% HNO3, it is referred to as fuming nitric acid. Depending on the amount of nitrogen dioxide present, fuming nitric acid is further characterized as red fuming nitric acid at concentrations above 86%, or white fuming nitric acid at concentrations above 95%. Uses: Intermediate for chemical syntheses.Intermediate in manufacture of inorganic and organicchemicals incl. fertilizers.Formulation of mixtures (fertilizer, metal surfacetreatment product, cleaning product, detergent andmaintenance product).Processing aid in industry, including laboratoryapplications, such as pH regulator, neutralisationagent, oxidising agent.Reactive agent in inorganic and organic synthesis.Regeneration of ion exchange resins.pH control.Laboratory agent.Surface treatment product. In cleaning products. CAS No. 7697-37-2. | |
| NITRIC ACID 99% (CONCENTRATED) | A inorganic compound with the formula HNO3. It is a highly corrosive mineral acid. The compound is colourless, but older samples tend to be yellow cast due to decomposition into oxides of nitrogen. Most commercially available nitric acid has a concentration of 68% in water. When the solution contains more than 86% HNO3, it is referred to as fuming nitric acid. Depending on the amount of nitrogen dioxide present, fuming nitric acid is further characterized as red fuming nitric acid at concentrations above 86%, or white fuming nitric acid at concentrations above 95%. Uses: Intermediate for chemical syntheses.Intermediate in manufacture of inorganic and organic chemicals incl. fertilizers.Formulation of mixtures (fertilizer, metal surface treatment product, cleaning product, detergentand maintenance product).Processing aid in industry, including laboratory applications, such as pH regulator, neutralisationagent, oxidising agent.Reactive agent in inorganic and organic synthesis.Regeneration of ion exchange resins.pH control.Laboratory agent.Surface treatment product.In cleaning products. CAS No. 007-004-00-1. | |
| NO-Indomethacin | NO-indomethacin is a hybrid drug containing an NSAID indomethacin and a nitric oxide (NO) donor. It combines anti-inflammatory properties of indomethacin and gastrointestinal protective effects of NO, exhibiting reduced gastrointestinal and kidney toxicity compared to indomethacin alone. Group: Pharmaceutical. Alternative Names: NCX 2121; 4-nitrooxybutyl (2R)-2-acetamido-3-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]sulfanylpropanoate. CAS No. 301838-28-8. Pack Sizes: 1mg;1g;10g. Product ID: 301838-28-8. Molecular formula: C28H30ClN3O9S. Mole weight: 620.1. Custom synthesis is available. Send your inquiries for more information. | London |
| NO-Losartan A | NO-losartan A is a hybrid drug containing an angiotensin II type 1 (AT1) receptor antagonist losartan and a nitric oxide (NO) donor. Losartan is an anti-hypertensive agent, and the NO exhibits vasodilating effects. Group: Pharmaceutical. Alternative Names: Losartan 3-[(nitrooxy)methyl]benzoate; [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methyl 3-(nitrooxymethyl)benzoate. CAS No. 791122-48-0. Pack Sizes: 1mg;1g;10g. Product ID: 791122-48-0. Molecular formula: C30H28ClN7O5. Mole weight: 602. Custom synthesis is available. Send your inquiries for more information. | London |
| Osthol | Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also regulates the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. Osthole is a natural compound used in cosmetics material. Uses: Anti-tumor; anti-cancer; may be used as bio-pesticides. Group: Pharmaceutical. Alternative Names: Osthol; 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one. CAS No. 484-12-8. Pack Sizes: 100 g. Product ID: NP1032. Molecular formula: C15H16O3. Mole weight: 244.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Pteryxin | Pteryxin, a natural coumarin compound found in the herbs of Peucedanum harry-smithii var. subglabrum, shows muscle-relaxant property. Pteryxin exhibits hepatoprotective and nitric oxide production inhibitory activity. Uses: Muscle-relaxant. Group: Pharmaceutical. Alternative Names: (Z)-2-Methyl-2-butenoic acid[(9R)-9-acetoxy-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10α-yl] ester. CAS No. 13161-75-6. Pack Sizes: 25 mg. Product ID: NP1099. Molecular formula: C21H22O7. Mole weight: 386.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Rhodamine B hydrazide | Rhodamine B hydrazide is a water-soluble fluorescent probe used for the detection of copper, peroxynitrite, nitric oxide, hydrogen peroxide, glucose, diacetyl, and hemoglobin. Group: Pharmaceutical. Alternative Names: 2-amino-3',6'-bis(diethylamino)-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one. CAS No. 74317-53-6. Pack Sizes: 100 mg. Product ID: B2708-031878. Molecular formula: C28H32N4O2. Mole weight: 456.6. Custom synthesis is available. Send your inquiries for more information. | London |
| SDMA | An endogenous inhibitor of nitric oxide (NO) synthase activity. Group: Pharmaceutical. Alternative Names: (2S)-2-amino-5-[(N,N'-dimethylcarbamimidoyl)amino]pentanoic acid; guanidino-N(1),N(2)-dimethylarginine; N(G1),N(G2)-dimethylarginine; N,N'-dimethylarginine; NG,N'G-dimethyl-L-arginine; omega-N(G),N'(G)-dimethylarginine; sDMA arginine; symmetric dimethylarginine. CAS No. 30344-00-4. Pack Sizes: 50 mg. Product ID: B0084-105642. Molecular formula: C8H18N4O2. Mole weight: 202.25. Custom synthesis is available. Send your inquiries for more information. | London |
| sesamolin | Sesamin and sesamolin have been demonstrated to possess several bioactivities beneficial for human health. Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated when they were pretreated with sesamin or sesamolin. The neuroprotective effect of sesamin and sesamolin was also observed in vivo using gerbils subjected to a focal cerebral ischemia induced by occlusion of the right common carotid artery and the right middle cerebral artery. Group: Pharmaceutical. Alternative Names: (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. CAS No. 526-07-8. Pack Sizes: 100 mg. Product ID: B2703-464796. Molecular formula: C20H18O7. Mole weight: 370.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Tylvalosin | Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Group: Pharmaceutical. Alternative Names: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. CAS No. 63409-12-1. Pack Sizes: 10 mg. Product ID: BBF-05837. Molecular formula: C53H87NO19. Mole weight: 1042.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Uncinatone | Uncinatone is a natural diterpenoid found in the roots of Clerodendrum bungei Steud. Uncinatone shows inhibition of lipopolysaccharide-induced nitric oxide production and inhibitory activity against complement system. Group: Pharmaceutical. Alternative Names: cis-1,8,9,11b-Tetrahydro-7,11-dihydroxy-3,4,9,11b-tetramethylphenanthro[3,2-b]furan-6(2H)-one. CAS No. 99624-92-7. Pack Sizes: 5 mg. Product ID: NP6610. Molecular formula: C20H22O4. Mole weight: 326.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Strontium nitrate | A inorganic compound composed of the elements strontium, nitrogen and oxygen with the formula Sr (NO 3) 2. This colourless solid is used as a red colorant and oxidizer in pyrotechnics. Strontium nitrate is typically generated by the reaction of nitric acid on strontium carbonate. Uses: Uses in pyrotechnics. Manufacture of substances. Laboratory reagent. CAS No. 10042-76-9. | |
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