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| Product | Description | |
|---|---|---|
| Niraparib | Niraparib is an inhibitor of PARP, which was approved by FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy. Group: Pharmaceutical. Alternative Names: MK-4827; MK 4827; MK4827; (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; ZEJULA; 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide. CAS No. 1038915-60-4. Pack Sizes: 100 mg. Product ID: B0084-408479. Molecular formula: C19H20N4O. Mole weight: 320.396. Custom synthesis is available. Send your inquiries for more information. |  London |
| MK-4827 (R-enantiomer) | MK-4827 (R-enantiomer) is the R form of MK-4827, which is a PARP inhibitor developed for the treatment of ovarian cancer. Group: Pharmaceutical. Alternative Names: (R)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; Niraparib R-enantiomer; MK4827 R-enantiomer; MK 4827 R-enantiomer; MK-4827 R-enantiomer. CAS No. 1038915-58-0. Pack Sizes: 5 mg. Product ID: B0084-138719. Molecular formula: C19H20N4O. Mole weight: 320.396. Custom synthesis is available. Send your inquiries for more information. | London |
| MK-4827 tosylate | MK-4827 tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. It has a great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1. Group: Pharmaceutical. Alternative Names: (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate; MK-4827; MK-4827; MK4827; MK4827-tosylate; Niraparib tosylate. CAS No. 1038915-73-9. Pack Sizes: 100 mg. Product ID: B0084-463500. Molecular formula: C26H28N4O4S. Mole weight: 492.59. Custom synthesis is available. Send your inquiries for more information. | London |
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