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| Product | Description | |
|---|---|---|
| Nintedanib-[13C,d3] | Nintedanib-[13C,d3] is the labelled analogue of Nintedanib. Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Group: Pharmaceutical. Alternative Names: Nintedanib 13CD3; [13C,2H3]-BIBF 1120; [13C,2H3]-Intedanib; [13C,2H3]-Vargatef; methyl (Z)-3-(((4-(N-methyl-2-(4-(methyl-13C-d3)piperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate; Ofev-13C,d3. Pack Sizes: 5 mg. Product ID: BLP-006061. Molecular formula: C30[13C]H30D3N5O4. Mole weight: 543.65. Custom synthesis is available. Send your inquiries for more information. |  London |
| Nintedanib Ethanesulfonate (Intedanib Ethanesulfonate) | Nintedanib esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. Uses: The treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: Methyl (3Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino) (phenyl)methylidene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylate ethanesulfonate; BIBF1120; BIBF 1120 BIBF-1120; Nintedanib esylate Nintedanib ethanesulfonate salt; Intedanib; Brand name OFEV Vargatef. CAS No. 656247-18-6. Pack Sizes: 500 mg. Product ID: B0084-434827. Molecular formula: C33H39N5O7S. Mole weight: 649.76. Custom synthesis is available. Send your inquiries for more information. | London |
| Nintedanib Impurity 6 (Intedanib Impurity 6) | BIBF 1202 is the major in-vivo metabolite of BIBF 1120, which is an oral triple angiokinase inhibitor targeting VEGFR, PDGFR, FGFR. It is a related compound of Intedanib, which is an indolinone derivative that inhibits angiokinase and an antitumor agent. It is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (VEGF) signaling pathway thus inhibition of tumor angiogenesis. Uses: Bibf 1202 is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (vegf) signaling pathway thus inhibition of tumor angiogenesis. Group: Pharmaceutical. Alternative Names: BIBF-1202; BIBF 1202; BIBF1202. (3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid;(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid;Nintedanib Impurity 5. CAS No. 894783-71-2. Pack Sizes: 50 mg. Product ID: B0084-474893. Molecular formula: C30H31N5O4. Mole weight: 525.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Nintedanib Impurity D | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: (3Z)?-2,?3-Dihydro-3-[[[4-(methylamino)?phenyl]?amino]?phenylmethylene]?-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester. CAS No. 1987887-92-2. Pack Sizes: 100 mg. Product ID: B1421-478184. Molecular formula: C24H21N3O3. Mole weight: 399.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Nintedanib (Intedanib) | Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Group: Pharmaceutical. Alternative Names: Vargatef; BIBF-1120; BIBF 1120; BIBF1120; Intedanib. CAS No. 656247-17-5. Pack Sizes: 500 mg. Product ID: B0084-262244. Molecular formula: C31H33N5O4. Mole weight: 539.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Dimethyl 3,3'-(((((2,2'-(piperazine-1,4-diyl)bis(acetyl))bis(methylazanediyl))bis(4,1-phenylene))bis(azanediyl))bis(phenylmethanylylidene))(3Z,3'E)-bis(2-oxoindoline-6-carboxylate) | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: Nintedanib Impurity 50. CAS No. 2410284-90-9. Pack Sizes: 1 mg. Product ID: B2694-478193. Molecular formula: C56H52N8O8. Mole weight: 965.08. Custom synthesis is available. Send your inquiries for more information. | London |
| methyl 1-(2-chloroacetyl)-2-oxo-3H-indole-6-carboxylate | An impurity of Nintedanib, which is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/66 nM. Group: Pharmaceutical. Alternative Names: 1160293-25-3; methyl 1-(2-chloroacetyl)-2-oxoindoline-6-carboxylate1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl estermethyl 1-(2-chloroacetyl)-2-oxo-3H-indole-6-carboxylate1H-Indole-6-carboxylic acid, 1-(2-chloroacetyl)-2,3-dihydro-2-oxo-, methyl ester. CAS No. 1160293-25-3. Pack Sizes: 100 mg. Product ID: B2694-338804. Molecular formula: C12H10ClNO4. Mole weight: 267.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl 1-Acetyl-2-oxoindoline-6-carboxylate | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: 1-acetyl-2-oxo-3H-indole-6-carboxylic acid methyl ester; methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate. CAS No. 676326-36-6. Pack Sizes: 100 mg. Product ID: B1421-184191. Molecular formula: C12H11NO4. Mole weight: 233.22. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: N-methyl-2-(4-methyl-1-piperazinyl)-N-(4-nitrophenyl)acetamide; N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide. CAS No. 1139453-98-7. Pack Sizes: 100 mg. Product ID: B1421-258623. Molecular formula: C14H20N4O3. Mole weight: 292.33. Custom synthesis is available. Send your inquiries for more information. | London |
| N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. Alternative Names: N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide; 1038972-16-5; CS-0011633; N-Methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide (Nintedanib Impurity). CAS No. 1038972-16-5. Pack Sizes: 100 mg. Product ID: B1421-284921. Molecular formula: C13H18N4O3. Mole weight: 278.31. Custom synthesis is available. Send your inquiries for more information. | London |
| N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide hydrochloride | An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Group: Pharmaceutical. CAS No. 2037385-84-3. Pack Sizes: 100 mg. Product ID: B1421-284922. Molecular formula: C13H19ClN4O3. Mole weight: 314.77. Custom synthesis is available. Send your inquiries for more information. | London |
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