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Product
Neuropeptide AF (93-110), Human TFA salt Neuropeptide AF, an endogenous anti-opioid peptide involved in pain modulation and endocrine functions, may also regulate metabolism via stimulation of β-adrenoceptor expression in adipocytes. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-016479. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Neuropeptide FF Neuropeptide FF, which belongs to the RF-amide family of peptides, is an endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki= 2.82 and 0.21 nM respectively). Neuropeptide FF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol. Uses: Narcotic antagonists. Group: Pharmaceutical. Alternative Names: NPFF; H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2; L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide. CAS No. 99566-27-5. Pack Sizes: 5 mg. Product ID: BAT-010559. Molecular formula: C54H76N14O10. Mole weight: 1081.27. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Neuropeptide Y (29-64) Neuropeptide Y is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. Group: Pharmaceutical. Alternative Names: Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr; L-tyrosyl-L-prolyl-L-seryl-L-lysyl-L-prolyl-L-alpha-aspartyl-L-asparagyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-prolyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparagyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosine. CAS No. 303052-45-1. Pack Sizes: 5 mg. Product ID: BAT-009963. Molecular formula: C189H284N54O58S. Mole weight: 4272.66. Custom synthesis is available. Send your inquiries for more information. Categories: Neuropeptide Y(29-64). BOC Sciences
London
Neuropeptide Y (human, rat) Neuropeptide Y (human, rat) is a widely distributed endogenous neuropeptide involved in the control of food intake, sexual behavior and blood pressure. NPY has also been shown to interact with the immune system, promoting gastrointestinal inflammation, as well as exhibiting an antimicrobial effect against several gut bacteria. Group: Pharmaceutical. Alternative Names: NPY (human, rat). CAS No. 90880-35-6. Pack Sizes: 5 mg. Product ID: BAT-010562. Molecular formula: C189H285N55O57S. Mole weight: 4271.7. Custom synthesis is available. Send your inquiries for more information. Categories: Neuropeptide Y (human,rat). BOC Sciences
London
((Cys31,Nva34)-Neuropeptide Y (27-36))2 A potent Neuropeptide Y Y5 receptor agonist. Group: Pharmaceutical. Alternative Names: ((Cys31,Nva34)-NPY (27-36))2; BWX 46; (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2; (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2, (Disulfide bond). CAS No. 172997-92-1. Pack Sizes: 1 mg. Product ID: BAT-006094. Molecular formula: C116H186N36O28S2. Mole weight: 2597.07. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Agouti-related Protein (AGRP) (25-82), human Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006143. Molecular formula: C279H468N80O90S1. Mole weight: 6415.39. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Antagonist G Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Group: Pharmaceutical. Alternative Names: [Arg6,D-Trp7,9,N-MePhe8]-Substance P(6-11). CAS No. 115150-59-9. Pack Sizes: 1 mg. Product ID: BAT-006104. Molecular formula: C49H66N12O6S. Mole weight: 951.2. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
[Arg8]-Vasotocin TFA [Arg8]-Vasotocin TFA is a neuropeptide peptide of the vasopressin/oxytocin hormone family, which has the function of regulating adrenal cortex hormones. Group: Pharmaceutical. Alternative Names: 8-L-arginine-oxytocin, trifluoroacetate salt; L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide trifluoroacetic acid; H-Cys(1)-Tyr-Ile-Gln-Asn-Cys(1)-Pro-Arg-Gly-NH2.TFA. Pack Sizes: 25 mg. Product ID: BAT-009148. Molecular formula: C45H68F3N15O14S2. Mole weight: 1164.24. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
β-Endorphin (bovine, camel, mouse) β-Endorphin is an endogenous opioid neuropeptide. Uses: Neurotransmitter agents. Group: Pharmaceutical. Alternative Names: beta-Endorphin (bovine, camel, mouse); beta-Endorphin (1-31); H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln-OH. CAS No. 59887-17-1. Pack Sizes: 1 mg. Product ID: BAT-006202. Molecular formula: C155H250N42O44S. Mole weight: 3437.96. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
β-Endorphin (equine) β-Endorphin is an endogenous opioid neuropeptide which has analgesic properties. Group: Pharmaceutical. Alternative Names: beta-Endorphin (equine); H-Tyr-Gly-Gly-Phe-Met-Ser-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln-OH. CAS No. 79495-86-6. Pack Sizes: 5 mg. Product ID: BAT-006201. Molecular formula: C154H248N42O44S. Mole weight: 3423.94. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
BIBP 3226 TFA BIBP 3226 trifluoroacetate is a mixed non-peptide neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Ki = 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4 and rNPY Y5, respectively). BIBP 3226 exhibits an anxiogenic-like effect in rats following i.c.v. administration. Group: Pharmaceutical. Alternative Names: BIBP 3226 trifluoroacetate; BIBP3226 trifluoroacetate; BIBP-3226 trifluoroacetate; N-[(1R)]-4-[(Aminoiminomethyl)amino-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl-α-phenylbenzeneacetamide trifluoroacetate; N5-(Diaminomethylene)-N2-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-D-ornithinamide trifluoroacetate; Diphenylacetyl-D-Arg-4-hydroxybenzylamide trifluoroacetate. CAS No. 1068148-47-9. Pack Sizes: 25 mg. Product ID: BAT-010722. Molecular formula: C27H31N5O3.C2HF3O2. Mole weight: 587.59. Custom synthesis is available. Send your inquiries for more information. Categories: BIBP3226 TFA. BOC Sciences
London
Bombesin Bombesin is a neuropeptide with many biological effects such as hormone release, activation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. It binds to the gastrin-releasing peptide receptor (GRPR) in rat pancreatic acinar cells (Ki = 1.88 nM), and also to frog bombesin receptor subtype 4 (BB4) in CHO cells overexpressing the receptor (Ki = 1.7 nM). Uses: Neurotransmitter agents. Group: Pharmaceutical. Alternative Names: H-Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; L-pyroglutamyl-L-glutaminyl-L-arginyl-L-leucyl-glycyl-L-asparagyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide; Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2. CAS No. 31362-50-2. Pack Sizes: 10 mg. Product ID: BAT-006169. Molecular formula: C71H110N24O18S. Mole weight: 1619.85. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
CCK Octapeptide (non-sulfated) Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Group: Pharmaceutical. Alternative Names: CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine). CAS No. 25679-24-7. Pack Sizes: 5 mg. Product ID: BAT-006185. Molecular formula: C49H62N10O13S2. Mole weight: 1063. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cortistatin 14 (mouse, rat) Cortistatin-14 is an endogenous neuropeptide expressed in the cortex and hippocampus. Group: Pharmaceutical. Alternative Names: Cortistatin-14; H-PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH; CST-14; CST-14 (RAT). CAS No. 186901-48-4. Pack Sizes: 5 mg. Product ID: BAT-006189. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
LHRH (free acid) LHRH (free acid), also known as Luteinizing Hormone-Releasing Hormone free acid, is a neuropeptide that plays a crucial role in regulating reproduction. This hormone is secreted by the hypothalamus and acts on the anterior pituitary gland to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are essential for reproductive functions. Group: Pharmaceutical. Alternative Names: Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly; H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-OH; 10-Glycine-luteinizing hormone-releasing factor (swine); 10-Glycine-luteinizing hormone-releasing factor (pig); 10-Glycine-LH-RH; [Gly-OH10]-LHRH; LH-RH(OH); LHRH acid; PGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly; LHRH free acid; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-glycyl-L-leucyl-L-arginyl-L-prolyl-glycine; XHWSYGLRPG. CAS No. 35263-73-1. Pack Sizes: 1mg;1g;10g. Product ID: BAT-015735. Molecular formula: C55H74N16O14. Mole weight: 1183.27. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Netupitant Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Group: Pharmaceutical. Alternative Names: AGE94200; AGE-94200; AGE 94200;Ro 67-3189; Ro-67-3189; Ro67-3189; CHEBI441603; CID6451149; D05152; UNII-7732P08TIR, CHEMBL206253, AG-E-94200, Netupitant. CAS No. 290297-26-6. Pack Sizes: 50 mg. Product ID: B2693-465324. Molecular formula: C30H32F6N4O. Mole weight: 578.603. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Neuromedin U-23 (rat) trifluoroacetate Neuromedin U, a structurally highly conserved neuropeptide, is ubiquitously distributed, with highest levels found in the gastrointestinal tract and pituitary. Neuromedin U regulates blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function, and also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. Group: Pharmaceutical. Alternative Names: L-Tyrosyl-L-lysyl-L-valyl-L-asparaginyl-L-α-glutamyl-L-tyrosyl-L-glutaminylglycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-serylglycylglycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide trifluoroacetate; Rat neuromedin U-23 trifluoroacetate. Pack Sizes: 10 mg. Product ID: B1370-099069. Molecular formula: C126H181N34F3O33. Mole weight: 2756.99. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Neuromedin U-25 (human) trifluoroacetate salt Neuromedin U-25 (NMU-25) is a 25-amino acid neuropeptide found in CNS of humans, demonstrated to drive smooth muscle contraction and regulate blood pressure. In vivo study has shown that it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. Group: Pharmaceutical. Alternative Names: Human Neuromedin U-25 Trifluoroacetate; NMU-25 Trifluoroacetate; L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide, trifluoroacetate salt. Pack Sizes: 5 mg. Product ID: B1370-099047. Molecular formula: C141H203N41O38; XCF3COOH. Mole weight: 3080.37 (free base). Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Nociceptin Nociceptin, a 17 amino acid neuropeptide involved in a variety of biological systems, is the endogenous ligand of the nociceptin receptor, acting as a potent anti-analgesic. Group: Pharmaceutical. Alternative Names: Orphanin FQ; H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH; L-phenylalanyl-glycyl-glycyl-L-phenylalanyl-L-threonyl-glycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-alanyl-L-asparagyl-L-glutamine; Nociceptin/orphanin FQ; Nociceptin (1-17); Orphanin FQ (rat, human, swine). CAS No. 170713-75-4. Pack Sizes: 5 mg. Product ID: BAT-006193. Molecular formula: C79H129N27O22. Mole weight: 1809.04. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Olcegepant Olcegepant is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide (CGRP) receptor, primarily explored for the prevention of migraines in adults. CGRP is a neuropeptide that plays a significant role in migraine pathophysiology, and its receptors are found in the trigeminal ganglion and the central nervous system. By blocking the CGRP receptor, olcegepant aims to prevent the activation of pain pathways associated with migraines. Group: Pharmaceutical. Alternative Names: BIBN-4096; BIBN4096; BIBN 4096; BIBN-4096BS; BIBN4096BS; BIBN 4096BS; N-((R)-1-(((S)-6-Amino-1-oxo-1-(4-(pyridin-4-yl)piperazin-1-yl)hexan-2-yl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl)-4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxamide; 1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine. CAS No. 204697-65-4. Pack Sizes: 10 mg. Product ID: B0084-441440. Molecular formula: C38H47Br2N9O5. Mole weight: 869.65. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PACAP (1-27), human, ovine, rat Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). It is a potent PACAP receptor agonist. Group: Pharmaceutical. Alternative Names: PACAP 1-27; Pituitary Adenylate Cyclase Activating Polypeptide1-27; H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-glycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucinamide. CAS No. 127317-03-7. Pack Sizes: 1 mg. Product ID: BAT-006206. Molecular formula: C142H224N40O39S. Mole weight: 3147.6. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Peptide YY (3-36) Peptide YY (3-36) is a Y2/Y5 Neuropeptide Y receptor agonist (IC50= 0.11 nM for inhibition of 125I-PYY binding to Y2 receptor). Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. Group: Pharmaceutical. Alternative Names: Peptide YY (PYY) (3-36), human; H-Ala-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Ser-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2; L-alanyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-seryl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-leucyl-L-asparagyl-L-leucyl-L-valyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide; PYY (3-36) (canine, mouse, porcine, rat). CAS No. 126339-09-1. Pack Sizes: 5 mg. Product ID: BAT-006172. Molecular formula: C176H272N52O54. Mole weight: 3980.42. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Trofinetide Trofinetide is a NMDA antagonist under the development of Neuren Pharmaceuticals. It is an analogue of the neuropeptide (1-3) IGF-1, which is a simple tripeptide with sequence Gly-Pro-Glu formed by enzymatic cleavage of the growth factor IGF-1 within the brain. Phase II clinical trials against Fragile X syndrome and Rett syndrome are on-going. Uses: Brain injuries; fragile x syndrome; rett syndrome. Group: Pharmaceutical. Alternative Names: NNZ-2566; NNZ 2566; NNZ2566; Trofinetide; ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid. CAS No. 853400-76-7. Pack Sizes: 250 mg. Product ID: B1370-215136. Molecular formula: C13H21N3O6. Mole weight: 315.32. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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