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Neurokinin A (4-10), an endogenous neuromodulatory peptide formerly known as substance K, is an atachykinin NK2 receptor agonist. Group: Pharmaceutical. CAS No. 97559-35-8. Pack Sizes: 5 mg. Product ID: BAT-006163. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Neurokinin B TFA
Neurokinin B TFA, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Group: Pharmaceutical. CAS No. 101536-55-4. Pack Sizes: 10 mg. Product ID: BAT-009299. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetylaszonalenin
Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptor. Group: Pharmaceutical. CAS No. 42230-55-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-04519. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Fosaprepitant-[d4] Dimeglumine
Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Group: Pharmaceutical. Pack Sizes: 25 mg. Product ID: BLP-005503. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Maropitant citrate
Maropitant citrate is a neurokinin receptor antagonist, which was developed as a drug for the treatment of motion sickness and vomiting in dogs. Group: Pharmaceutical. CAS No. 359875-09-5. Pack Sizes: 50 mg. Product ID: B2693-112320. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Netupitant
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Group: Pharmaceutical. CAS No. 290297-26-6. Pack Sizes: 50 mg. Product ID: B2693-465324. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
RC 160
RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is a peptide neurokinin-1 receptor (NK1) antagonist and inhibits increases in vascular permeability stimulated by substance P in a concentration-dependent manner in isolated guinea pig trachea and main bronchi. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 103222-11-3. Pack Sizes: 5 mg. Product ID: BAT-006135. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Saredutant Impurities
Saredutant Impurities are crucial for ensuring the purity and efficacy of Saredutant, a potent neurokinin-2 receptor antagonist. This compound is primarily investigated in the treatment of anxiety and depression disorders. By identifying and controlling these impurities, researchers can enhance the therapeutic potential and safety of Saredutant formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Serlopitant
Serlopitant is a Neurokinin 1 (NK-1) receptor antagonist. Phase II clinical trials for the treatment of Prurigo nodularis and Pruritus are ongoing. Uses: Prurigo nodularis; pruritus. Group: Pharmaceutical. CAS No. 860642-69-9. Pack Sizes: 10 mg. Product ID: B1370-459936. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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