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| Product | Description | |
|---|---|---|
| Neurokinin A (4-10) | Neurokinin A (4-10), an endogenous neuromodulatory peptide formerly known as substance K, is an atachykinin NK2 receptor agonist. Group: Pharmaceutical. Alternative Names: H-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; (5S,8S,14S,17S,20S,23S)-23-amino-17-benzyl-5-carbamoyl-20-(hydroxymethyl)-8-isobutyl-14-isopropyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid. CAS No. 97559-35-8. Pack Sizes: 5 mg. Product ID: BAT-006163. Molecular formula: C34H54N8O10S. Mole weight: 766.91. Custom synthesis is available. Send your inquiries for more information. |  London |
| Neurokinin B TFA | Neurokinin B TFA, one of the tachykinin family of peptides, binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biological effect but shows preference for the NK-3 receptor. Group: Pharmaceutical. Alternative Names: Neurokinin B Trifluoroacetate; H-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2.TFA; L-alpha-aspartyl-L-methionyl-L-histidyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid. CAS No. 101536-55-4. Pack Sizes: 10 mg. Product ID: BAT-009299. Molecular formula: C55H79N13O14S2.C2HF3O2. Mole weight: 1324.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Fosaprepitant-[d4] Dimeglumine | Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Group: Pharmaceutical. Alternative Names: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Pack Sizes: 25 mg. Product ID: BLP-005503. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86. Custom synthesis is available. Send your inquiries for more information. | London |
| GR 64349 | GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon). Group: Pharmaceutical. Alternative Names: GR 64349; GR64349; GR-64349; LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2; [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10); L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidi. CAS No. 137593-52-3. Pack Sizes: 1 mg. Product ID: BAT-010280. Molecular formula: C42H68N10O11S. Mole weight: 921.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Hemokinin 1, human TFA | Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. It can produce an opioid-independent analgesia. Group: Pharmaceutical. Alternative Names: Hemokinin 1 (human) (trifluoroacetate salt); L-threonylglycyl-L-lysyl-L-alanyl-L-seryl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide, trifluoroacetate salt. Pack Sizes: 25 mg. Product ID: B1370-382714. Molecular formula: C56H85F3N14O16S. Mole weight: 1299.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Maropitant citrate | Maropitant citrate is a neurokinin receptor antagonist, which was developed as a drug for the treatment of motion sickness and vomiting in dogs. Group: Pharmaceutical. Alternative Names: ACIDUM CITRICUM ANHYDRICUM; 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID; B-HYDROXYTRICARBALLYLIC ACID; HYDROXYTRICARBALLYLIC ACID; FEMA 2306; CEFIXIM TELLURITE SUPPLEMENT; CITRATE ION CHROMATOGRAPHY STANDARD; CT SUPPLEMENT. CAS No. 359875-09-5. Pack Sizes: 50 mg. Product ID: B2693-112320. Molecular formula: C38H50N2O9. Mole weight: 678.8. Custom synthesis is available. Send your inquiries for more information. | London |
| Netupitant | Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Group: Pharmaceutical. Alternative Names: AGE94200; AGE-94200; AGE 94200;Ro 67-3189; Ro-67-3189; Ro67-3189; CHEBI441603; CID6451149; D05152; UNII-7732P08TIR, CHEMBL206253, AG-E-94200, Netupitant. CAS No. 290297-26-6. Pack Sizes: 50 mg. Product ID: B2693-465324. Molecular formula: C30H32F6N4O. Mole weight: 578.603. Custom synthesis is available. Send your inquiries for more information. | London |
| RC 160 | RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is a peptide neurokinin-1 receptor (NK1) antagonist and inhibits increases in vascular permeability stimulated by substance P in a concentration-dependent manner in isolated guinea pig trachea and main bronchi. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-tryptophanamide, cyclic (2→7)-disulfide; BMY-41606; BMY 41606; BMY41606; RC160; RC-160; DP-05-094; Octastatin; L-Tryptophanamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2→7)-disulfide; RC 160 (protein); Vapreotide; D-Phe-Cys-Trp-D-Trp-Lys-Val-Cys-Trp-CONH2 (Disulfide bridge: Cys2-Cys7). CAS No. 103222-11-3. Pack Sizes: 5 mg. Product ID: BAT-006135. Molecular formula: C57H70N12O9S2. Mole weight: 1131.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Serlopitant | Serlopitant is a Neurokinin 1 (NK-1) receptor antagonist. Phase II clinical trials for the treatment of Prurigo nodularis and Pruritus are ongoing. Uses: Prurigo nodularis; pruritus. Group: Pharmaceutical. Alternative Names: VPD-737; VPD737; VPD 737; MK-0594; MK 0594; MK0594; 3-((3aR,4R,5S,7aS)-5-((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-4-(4 fluorophenyl)octahydro-2H-isoindol-2-yl)cyclopent-2-en-1-one. CAS No. 860642-69-9. Pack Sizes: 10 mg. Product ID: B1370-459936. Molecular formula: C29H28F7NO2. Mole weight: 555.53. Custom synthesis is available. Send your inquiries for more information. | London |
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