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| Product | Description | |
|---|---|---|
| Necrosulfonamide | Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29, which significantly decreases BV6/DAC-induced cell death in MV4-11 cells. It prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Group: Pharmaceutical. Alternative Names: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide. CAS No. 1360614-48-7. Pack Sizes: 100 mg. Product ID: B1370-170273. Molecular formula: C18H15N5O6S2. Mole weight: 461.47. Custom synthesis is available. Send your inquiries for more information. |  London |
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