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NE 100 hydrochloride NE 100 hydrochloride is a σ1 receptor antagonist with IC50 value of 4.16 nM. It displays antipsychotic activity in vivo. Uses: Antipsychotic agents. Group: Pharmaceutical. Alternative Names: NE100 Hydrochloride; NE-100 Hydrochloride; NE100 HCl; NE-100 HCl; NE 100 HCl; 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride. CAS No. 149409-57-4. Pack Sizes: 100 mg. Product ID: B1370-129559. Molecular formula: C23H34ClNO2. Mole weight: 391.97. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Group: Pharmaceutical. Alternative Names: 1038924-71-8; (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid;hydrochloride; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride; SCHEMBL597864. CAS No. 1038924-71-8. Pack Sizes: 100 mg. Product ID: B2694-013668. Molecular formula: C18H22ClNO2. Mole weight: 319.8. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
4-(N-Phenylamidino)thiazole hydrochloride 4-(N-Phenylamidino)thiazole hydrochloride, a chemical compound with potential therapeutic benefits, has been investigated for its ability to target specific enzymes involved in the replication of cancer cells and viruses. Extensive research has been conducted on this compound through both in vitro and in vivo models, with preclinical studies indicating promising results. However, further inquiry is needed to fully comprehend its potential applications in the biomedical industry. Group: Pharmaceutical. Alternative Names: 4-Thiazolecarboxamidine, N-phenyl-, hydrochloride; 4-Thiazolecarboximidamide, N-phenyl-, hydrochloride. CAS No. 13631-64-6. Pack Sizes: 100 mg. Product ID: B1370-083565. Molecular formula: C10H10ClN3S. Mole weight: 239.7245. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
6-Desacetyl-6-Bromo Palbociclib Hydrochloride An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Group: Pharmaceutical. Alternative Names: 6-bromo-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride. CAS No. 850918-83-1. Pack Sizes: 100 mg. Product ID: B1476-284929. Molecular formula: C22H27ClBrN7O. Mole weight: 520.86. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
6-Desacetyl Palbociclib Hydrochloride An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Group: Pharmaceutical. Alternative Names: 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride. CAS No. 571189-66-7. Pack Sizes: 100 mg. Product ID: B1476-284928. Molecular formula: C22H28ClN7O. Mole weight: 441.96. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
ABT 089 dihydrochloride ABT 089 dihydrochloride is a selective α4β2 nicotinic acetylcholine receptor partial agonist (Ki = 16 nM) with >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors, respectively. ABT 089 dihydrochloride is used as a nootropic and neuroprotective agent. Uses: Nootropic and neuroprotective agent. Group: Pharmaceutical. Alternative Names: ABT 089 dihydrochloride; ABT089 dihydrochloride; ABT-089 dihydrochloride; 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride; Pozanicline hydrochloride. CAS No. 161416-61-1. Pack Sizes: 1mg;1g;10g. Product ID: 161416-61-1. Molecular formula: C11H16N2O.2HCl. Mole weight: 265.18. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Afobazole hydrochloride Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Group: Pharmaceutical. Alternative Names: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. CAS No. 173352-39-1. Pack Sizes: 100 mg. Product ID: B2693-463567. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Ambroxol hydrochloride AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. It is used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain. Uses: Expectorants. Group: Pharmaceutical. Alternative Names: Ambroxol hydrochloride; NA-872; NA872; NA 872; Abrohexal; Ambril; Ambro-Puren Ambrobeta; Duramucal; Ebromin; Mucosolvan. CAS No. 23828-92-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3423. Molecular formula: C13H18Br2N2O.HCl. Mole weight: 414.56. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Moxifloxacin Hydrochloride Moxifloxacin exerts its effects by trapping a DNA drug enzyme complex and specifically inhibiting ATP-dependent enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. It is a fluoroquinolone antibiotic with broad-spectrum bactericidal activity against gram-positive and gram-negative strains. Group: Pharmaceutical. Alternative Names: BAY12-8039 HCl; BAY12 8039 HCl; BAY128039 HCl; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Hydrochloride (1:1); Actira; Avalox; Lapinix; Moxifloxacine Hydrochloride; Octegra. CAS No. 186826-86-8. Pack Sizes: 100 g. Product ID: BBF-04614. Molecular formula: C21H24FN3O4.HCl. Mole weight: 437.89. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Pabociclib Impurity B Hydrochloride An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Group: Pharmaceutical. Alternative Names: tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate hydrochloride. CAS No. 1883672-48-7. Pack Sizes: 100 mg. Product ID: B1476-284924. Molecular formula: C29H38ClN7O4. Mole weight: 584.11. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Palbociclib N-oxide Hydrochloride An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Group: Pharmaceutical. Alternative Names: PD-0332991 hydrochloride; 1-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide Hydrochloride salt. Pack Sizes: 100 mg. Product ID: B1370-451980. Molecular formula: C24H30ClN7O3. Mole weight: 499.99. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PRE-084 PRE-084 Hydrochloride is a selective sigma-1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). PRE-084 is selective for PCP receptors (IC50 > 100000 nM) and several other receptor systems. It exhibits neuroprotective property. Group: Pharmaceutical. Alternative Names: 2-(4-Morpholinyl)ethyl 1-phenylcyclohexanecarboxylate hydrochloride; PRE-084 (hydrochloride); PRE 084 (hydrochloride); PRE084 (hydrochloride). CAS No. 138847-85-5. Pack Sizes: 100 mg. Product ID: B0084-067682. Molecular formula: C19H27NO3. Mole weight: 317.4. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PXS 4728A PXS 4728A is a VAP-1 (aka SSAO/AOC3) inhibitor with IC50 values 5 nM in the clinical trial for the treatment of non-alcoholic steatohepatitis (NASH). Studies show that it inhibits neutrophil rolling and tethering in mouse cremaster model, and alleviates respiratory inflammation in multiple models. Uses: Treatment of non-alcoholic steatohepatitis (nash). Group: Pharmaceutical. Alternative Names: BI-1467335 HCl; (E)-4-((2-(aminomethyl)-3-fluoroallyl)oxy)-N-(tert-butyl)benzamide hydrochloride. CAS No. 1478364-68-9. Pack Sizes: 100 mg. Product ID: B2693-054564. Molecular formula: C15H21FN2O2.HCl. Mole weight: 316.8. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Rac-cis-Sertraline Hydrochloride Rac-cis-Sertraline Hydrochloride is an extensively utilized pharmacological compound within the biomedical sector used in studying psychiatric afflictions, including depression, panic disorder and obsessive-compulsive disorder. Its mechanism of action entails selective inhibition of serotonin reuptake, thereby reestablishing homeostasis of this pivotal neurotransmitter within the cerebral research. Uses: Potent and selective inhibitors of serotonin uptake. Group: Pharmaceutical. Alternative Names: cis racemic Setraline; rac-cis-Sertraline Hydrochloride. CAS No. 79617-95-1. Pack Sizes: 100 mg. Product ID: B1331-134752. Molecular formula: C17H18Cl3N. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Tebanicline hydrochloride Tebanicline hydrochloride is the hydrochloride salt of Tebanicline (ABT-594) which is a neuronal nicotinic acetyl-choline receptor agonist and has been described as a breakthrough inanalgesia. Group: Pharmaceutical. Alternative Names: Tebanicline HCl; ABT-594 hydrochloride; Pyridine, 5-[(2R)-2-azetidinylmethoxy]-2-chloro-, monohydrochloride. CAS No. 203564-54-9. Pack Sizes: 100 mg. Product ID: B1370-007298. Molecular formula: C9H12Cl2N2O. Mole weight: 235.11. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(±)-Vesamicol hydrochloride (±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (Ki = 2 nM) that blocks the loading of acetylcholine into synaptic vesicles of cholinergic nerve terminals. The inhibition by Vesamicol attenuates acetylcholine neuronal signaling without direct effecys on signaling mechanisms. Group: Pharmaceutical. Alternative Names: AH5183 hydrochloride; AH 5183 hydrochloride; (±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride; 2-(4-Phenylpiperidino)cyclohexanol hydrochloride; Cyclohexanol, 2-(4-phenylpiperidino)-, hydrochloride. CAS No. 120447-62-3. Pack Sizes: 100 mg. Product ID: B1370-072516. Molecular formula: C17H25NO.HCl. Mole weight: 295.85. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PNU-282987 hydrochloride PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). Group: Pharmaceutical. Alternative Names: PNU-282987; PNU 282987; PNU282987; Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-. CAS No. 123464-89-1. Pack Sizes: 100 mg. Product ID: B0084-209211. Molecular formula: C14H18Cl2N2O. Mole weight: 301.21. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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