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| Product | Description | |
|---|---|---|
| 4,4'-Diaminodiphenylsulfone | Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase. Uses: Anti-inflammatory agent. Group: Pharmaceutical. CAS No. 80-08-0. Pack Sizes: 1 kg. Product ID: NP2822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| A-500359A | A-500359A is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has the activity of inhibiting translocase-1, IC50 is 0.017 μmol/L, and the IC50 of inhibiting peptidoglycan biosynthesis is 0.68 μmol/L. It also has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. CAS No. 254449-20-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359C | A-500359C is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. CAS No. 254449-21-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03174. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359D | A-500359D is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. CAS No. 254449-22-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03175. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359E | A-500359E is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03176. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359F | A-500359F is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03177. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359G | A-500359G is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03178. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359H | A-500359H is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03179. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359 M-1 | A-500359 M-1 is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03180. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-500359 M-2 | A-500359 M-2 is a bacterial translocase-1 (Translocase I, EC 2.7. 8.13) inhibitor produced by Streptomyces griseus SANK 60196. It has activity against Mycobacterium smegmatis, Streptococcus pneumoniae and Streptococcus pyogenes, with an MIC of 6.25-12.5 μg/mL. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03181. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetohydrazide-[d3] | Acetohydrazide-[d3] is a labelled analogue of Acetohydrazide, a metabolite of Isoniazid. Isoniazid is an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Group: Pharmaceutical. CAS No. 1028333-41-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003208. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Actithiazci acid | Actithiazci acid is an antibiotic produced from Streptomyces viginiae. Actithiazci acid is only resistant to Mycobacterium, and the MIC for Mycobacterium tuberculosis H37 Rv is 0.06 25-0.125 μg/mL. Used in Japan as an anti-nuclear drug. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00029. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bedaquiline fumarate | Bedaquiline fumarate is an anti-tuberculosis drug which selectively inhibits the mycobacterial energy metabolism and found to be effective against all states of Mycobacterium tuberculosis. It possesses a unique mechanism of action that disrupts the activity of the mycobacterial adenosine triphosphate synthase. It has an excellent in vitro activity against Mycobacterium tuberculosis, including multidrug resistant M tuberculosis, however, its side effect profile limits its use against MDR-TB when no other effective regimen can be provided. Uses: Antitubercular agents. Group: Pharmaceutical. CAS No. 845533-86-0. Pack Sizes: 200 mg. Product ID: B0084-463644. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cordycepin | It is produced by the strain of Cordyceps militaris and Aspergillus niaulans. Cordycepin can inhibit RNA biosynthesis and has anti-gram-positive and mycobacterium activities. Cordycepin has attracted much attention from scholars in the fields of anti-aging, health care, and new drug development. Uses: Anti-metastatic. Group: Pharmaceutical. CAS No. 73-03-0. Pack Sizes: 1 g. Product ID: BBF-01737. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Delamanid | Delamanid is used for the treatment of multi-drug-resistant tuberculosis. It functions by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. Uses: The treatment of multi-drug-resistant tuberculosis. Group: Pharmaceutical. CAS No. 681492-22-8. Pack Sizes: 100 mg. Product ID: B0084-459437. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ethambutol Impurities | Ethambutol Impurities assume a crucial role in the progressive refinement of anti-tuberculosis pharmaceutics, where their meticulous examination assures the effectiveness and safety of ethambutol compositions. By facilitating purity enhancement, such impurities bolster therapeutic efficacy against Mycobacterium tuberculosis, thus underpinning the advancement of treatment modalities in combating this infectious disease. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoniazid Impurities | Isoniazid Impurities are indispensable in pharmaceutical research, playing a crucial role in tuberculosis therapeutics. They facilitate the comprehension of stability, efficacy, and safety profiles of isoniazid, thereby ensuring its therapeutic prowess against Mycobacterium tuberculosis. Such impurities are key in advancing analytical methodologies and optimizing pharmaceutical formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isothymusin | Isothymusin is isolated from the herbs of Limnophila geoffrayi. It exhibits inhibitory activity against Mycobacterium tuberculosis. Uses: Antioxidant activity; antimycobacterial. Group: Pharmaceutical. CAS No. 98755-25-0. Pack Sizes: 5 mg. Product ID: NP2134. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PA-824 | PA-824, a bioreductive drug. PA-824 has potent in vitro activity against Mycobacterium tuberculosis. PA-824 was tested in vitro against a broad panel of multidrug-resistant clinical isolates and was found to be highly active against all isolates (MIC<1 microg/ml). PA-824 showed significant activity at 2, 10, and 50 microg/ml, similar to that of metronidazole, in a dose-dependent manner. Group: Pharmaceutical. CAS No. 187235-37-6. Pack Sizes: 100 mg. Product ID: B0084-341037. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rifabutin EP Impurity D | A derivative of Rifabutin.Rifabutin is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex. Group: Pharmaceutical. CAS No. 62041-01-4. Pack Sizes: 100 mg. Product ID: B2694-181302. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rifabutin Impurities | Rifabutin Impurities, essential to biomedical quality assurance, undergo rigorous analysis to affirm the purity and potency of rifabutin, a crucial antibacterial utilized in treating mycobacterial infections such as Mycobacterium avium complex (MAC) in HIV patients and tuberculosis. This identification process underpins stringent pharmacological standards, safeguarding therapeutic efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TBA-354 | TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greater than that of PA-824. TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. TBA-354 is 5 to 10 times more potent than PA-824, but selected mutants are cross-resistant to PA-824 and delamanid. TBA-354 is 2 to 4 times more potent than PA-824 when combined with bedaquiline, and when administered at a dose equivalent to that of PA-824, TBA-354 demonstrated superior sterilizing efficacy. TBA-354 has high bioavailability and a long elimination half-life. In vitro studies suggest a low risk of drug-drug interactions. Low-dose aerosol infection models of acute and chronic murine tuberculosis reveal time- and dose-dependent in vivo bactericidal activity that is at least as potent as that of delamanid and more potent than that of PA-824. Group: Pharmaceutical. CAS No. 1257426-19-9. Pack Sizes: 100 mg. Product ID: B2693-463155. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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