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| Product | Description | |
|---|---|---|
| YIL 781 | YIL 781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM). YIL 781 inhibits ghrelin to reduce insulin secretion both in vivo and in vitro. YIL 781 may be beneficial for the treatment of obesity and diabetes. Uses: Potential treatment of obesity and diabetes. Group: Pharmaceutical. Alternative Names: YIL781; YIL-781; (S)-6-(4-Fluorophenoxy)-3-((1-isopropylpiperidin-3-yl)methyl)-2-methylquinazolin-4(3H)-one. CAS No. 875258-85-8. Pack Sizes: 25 mg. Product ID: B1370-129708. Molecular formula: C24H28FN3O2. Mole weight: 409.51. Custom synthesis is available. Send your inquiries for more information. |  London |
| YIL781 hydrochloride | YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist with no significant affinity for the motilin receptor. It inhibits ghrelin to reduce insulin secretion both in vivo and in vitro. It may be beneficial for the treatment of obesity and diabetes. Group: Pharmaceutical. Alternative Names: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone hydrochloride; 4(3H)-Quinazolinone, 6-(4-fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-, hydrochloride (1:1); 6-(4-Fluorophenoxy)-3-{[(3S)-1-isopropyl-3-piperidinyl]methyl}-2-methyl-4(3H)-quinazolinone hydrochloride (1:1). CAS No. 1640226-17-0. Pack Sizes: 50 mg. Product ID: B1370-381845. Molecular formula: C24H29ClFN3O2. Mole weight: 445.96. Custom synthesis is available. Send your inquiries for more information. | London |
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