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Monomethyl auristatin E (vedotin) Monomethyl auristatin E (vedotin). Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 474645-27-7. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Cenik Chemicals
Cenik Chemicals
MC-Val-Cit-PAB-MMAE MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. Group: Pharmaceutical. Alternative Names: VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Vedotin. CAS No. 646502-53-6. Pack Sizes: 1 mg. Product ID: BBF-05783. Molecular formula: C68H105N11O15. Mole weight: 1316.63. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
MMAE Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: MMAE; Vedotin; Monomethyl auristatin E; Monomethylauristatin E; N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide. CAS No. 474645-27-7. Pack Sizes: 25 mg. Product ID: BBF-05782. Molecular formula: C39H67N5O7. Mole weight: 717.98. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
MMAE-[d8] MMAE-[d8] is a labelled analogue of MMAE, which is a potent mitotic inhibitor and a tubulin inhibitor. Group: Pharmaceutical. Alternative Names: D8-MMAE; D8-Monomethyl auristatin E. CAS No. 2070009-72-0. Pack Sizes: 10 mg. Product ID: BLP-012288. Molecular formula: C39H59D8N5O7. Mole weight: 726.03. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
MMAF Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: Monomethylauristatin F; Monomethyl Auristatin F; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; Monomethylauristatin Phenylalanine; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. CAS No. 745017-94-1. Pack Sizes: 10 mg. Product ID: BBF-05779. Molecular formula: C39H65N5O8. Mole weight: 731.48. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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