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MKC-3946 MKC-3946 is a potent inhibitor of inositol-requiring enzyme 1α (IRE1α). It inhibits XBP1 mRNA splicing and exhibits cytotoxicity against AML cells. MKC-3946 leads to modest growth inhibition in MM cells but has no effect on normal mononuclear cells in vitro. Group: Pharmaceutical. Alternative Names: MKC-3946; MKC 3946; MKC3946; 2-hydroxy-6-(5-(4-methylpiperazine-1-carbonyl)thiophen-2-yl)-1-naphthaldehyde. CAS No. 1093119-54-0. Pack Sizes: 300 mg. Product ID: B0084-054003. Molecular formula: C21H20N2O3S. Mole weight: 380.462. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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