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| Product | Description | |
|---|---|---|
| Miltefosine | Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: n-hexadecylphosphocholine; Hexadecylphosphocholine; Miltex; Impavido; 2-[[(Hexadecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethylethanaminium; MAPCHO®-16; C-16Miltefosine. CAS No. 58066-85-6. Pack Sizes: 5 g. Product ID: BBF-03908. Molecular formula: C21H46NO4P. Mole weight: 407.57. Custom synthesis is available. Send your inquiries for more information. |  London |
| Perifosine | Perifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine. Group: Pharmaceutical. Alternative Names: KRX-0401; KRX 0401; KRX0401; NKA17; NSC639966; NSC 639966; NSC-639966; D 21266; D-21266; D21266; D-21266N; N-Dimethylpiperidinium-4-yl(octadecyl)phosphate; 1,1-Dimethyl-4-[[(octadecyloxy)hydroxyphosphoryl]oxy]piperidinium inner salt. CAS No. 157716-52-4. Pack Sizes: 500 mg. Product ID: B0084-084985. Molecular formula: C25H52NO4P. Mole weight: 461.668. Custom synthesis is available. Send your inquiries for more information. | London |
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