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| Product | Description | |
|---|---|---|
| 1-Methyl-1-pentylpyrrolidinium Bis(trifluoromethanesulfonyl)imide | 1-Methyl-1-pentylpyrrolidinium Bis(trifluoromethanesulfonyl)imide. Group: Pharmaceutical. Alternative Names: N-Pentyl-N-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide. CAS No. 380497-17-6. Pack Sizes: 10 g. Product ID: 380497-17-6. Molecular formula: C12H22F6N2O4S2. Mole weight: 436.43. Custom synthesis is available. Send your inquiries for more information. |  London |
| 1-Methylpyrrolidine | 500g Pack Size. Group: Building Blocks, Organics. Formula: C5H11N. CAS No. 120-94-5. Prepack ID : 51308648-500g. Molecular Weight : 85.15. |  |
| (3R,5S)-5-Biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. Alternative Names: 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-. CAS No. 1038924-70-7. Pack Sizes: 100 mg. Product ID: B1604-479385. Molecular formula: C18H19NO. Mole weight: 265.356. Custom synthesis is available. Send your inquiries for more information. | London |
| A 844606 | A 844606 is a selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist (EC50 = 1.4 and 2.2 μM at human and rat receptors, respectively). It has no measurable effect on α4β2 nAChRs. Group: Pharmaceutical. Alternative Names: A 844606; A844606; A-844606; 2-(Hexahydro-5-methylpyrrolo[3,4-c]pyrrol-2(1H)-yl)-9H-xanthen-9-one. CAS No. 861119-08-6. Pack Sizes: 1mg;1g;10g. Product ID: 861119-08-6. Molecular formula: C20H20N2O2. Mole weight: 320.38. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-239 | ABT-239 is a novel, highly efficacious, non-imidazole class of H3R antagonist has been investigated as a treatment for ADHD, Alzheimer's disease, and schizophrenia. Uses: H3-receptor inverse agonist. Group: Pharmaceutical. Alternative Names: ABT-239; ABT 239; ABT239; 4-(2-{2-[(2R)-2-Methylpyrrolidin-1-yl]ethyl}- benzofuran-5-yl)benzonitrile. CAS No. 460746-46-7. Pack Sizes: 1mg;1g;10g. Product ID: 460746-46-7. Molecular formula: C22H22N2O. Mole weight: 330.42. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT 239 tartrate | ABT 239 tartrate is a potent and selective histamine H3 receptor antagonist or inverse agonist. Group: Pharmaceutical. Alternative Names: ABT 239 tartrate; ABT239 tartrate; ABT-239 tartrate; (2R,3R)-2,3-dihydroxybutanedioic acid; 4-[2-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]-1-benzofuran-5-yl]benzonitrile. CAS No. 460748-71-4. Pack Sizes: 1mg;1g;10g. Product ID: 460748-71-4. Molecular formula: C22H22N2O.C4H6O6. Mole weight: 480.51. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-418 hydrochloride | ABT-418 is a neuronal nicotinic acetylcholine receptor agonist with anxiolytic and cognition enhancing activities. Group: Pharmaceutical. Alternative Names: ABT-418 HCl; (S)-3-Methyl-5-(1-methylpyrrolidin-2-yl)-isoxazole HCl. CAS No. 147388-83-8. Pack Sizes: 1mg;1g;10g. Product ID: 147388-83-8. Molecular formula: C9H15ClN2O. Mole weight: 202.68. Custom synthesis is available. Send your inquiries for more information. | London |
| AC480 | AC480, also known as BMS-599626, is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. Group: Pharmaceutical. Alternative Names: BMS-599626; BMS 599626; BMS599626; AC 480; AC-480; Carbamic acid, N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester; (3S)-3-Morpholinylmethyl N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate; Carbamic acid, [4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester; N-[4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid, (3S)-3-morpholinylmethyl ester. CAS No. 714971-09-2. Pack Sizes: 1mg;1g;10g. Product ID: B0084-259278. Molecular formula: C27H27FN8O3. Mole weight: 530.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Anticefepime | Anticefepime is an impurity of Cefepime, an fourth generation cephalosporin antibiotic. Group: Pharmaceutical. Alternative Names: Cefepime Impurity A; (6R,7R)-7-[[(2E)-(2-Aminothiazol-4-yl)(methoxyimino)acetyl]amino]-3-[(1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefepime EP Impurity A; Anti-cefepime; E-Cefepime; (E)-Cefepime; 1-[[(6R,7R)-7-[[(2E)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidinium inner salt; Pyrrolidinium, 1-[[(6R,7R)-7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, inner salt; Pyrrolidinium, 1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, inner salt, [6R-[6α,7β(E)]]-; Cefepime dihydrochloride monohydrate EP Impurity A. CAS No. 97164-57-3. Pack Sizes: 25 mg. Product ID: B1370-153673. Molecular formula: C19H24N6O5S2. Mole weight: 480.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Cefepime Related Compound E | An impurity of Cefepime. Cefepime is a fourth-generation cephalosporin antibiotic known for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria. It is particularly effective against many organisms that are resistant to other antibiotics, including some beta-lactamase-producing strains. Cefepime is often used to treat severe infections such as pneumonia, urinary tract infections, and bloodstream infections. Group: Pharmaceutical. Alternative Names: 1-{[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium chloride; 7-Amino-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride; Pyrrolidinium, 1-[[(6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride; Pyrrolidinium, 1-[(7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl]-1-methyl-, hydroxide, inner salt, monohydrochloride, (6R-trans)-; USP Cefepime Related Compound E; Cefepime USP Related Compound E; Cefepime amine derivative; (6R,7R)-7-Amino-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate chloride. CAS No. 103121-85-3. Pack Sizes: 25 mg. Product ID: B0552-286040. Molecular formula: C13H20ClN3O3S. Mole weight: 333.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Micafungin Open-Ring Analog Sodium salt | Micafungin Open-Ring Analog Sodium salt is an impurity of Micafungin, an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections. Group: Pharmaceutical. Alternative Names: 5-((1S,2S,3S)-4-(((2S,3R)-5-Amino-1-((2S,3S,4S)-2-carbamoyl-3-hydroxy-4-methylpyrrolidin-1-yl)-3-hydroxy-1,5-dioxopentan-2-yl)amino)-3-((2S,4R)-1-(((2S,4R)-4,5-dihydroxy-1-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzoyl)pyrrolidine-2-carbonyl)-L-threonyl)-4-hydroxypyrrolidine-2-carboxamido)-1,2-dihydroxy-4-oxobutyl)-2-hydroxyphenyl hydrogen sulfate, Sodium Salt. CAS No. 539823-82-0. Pack Sizes: 10 mg. Product ID: B1370-071106. Molecular formula: C56H70N9NaO23S. Mole weight: 1292.26. Custom synthesis is available. Send your inquiries for more information. | London |
| MRTX849 | MRTX849 is a potent and mutation-selective covalent inhibitor of KRAS G12C. It maximizes inhibition by irreversibly locking the KRAS molecule in its inactive state, thereby preventing tumor cell growth which results in tumor cell death. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: MRTX-849; MRTX 849; Adagrasib; 2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile. CAS No. 2326521-71-3. Pack Sizes: 50 mg. Product ID: B2693-342068. Molecular formula: C32H35ClFN7O2. Mole weight: 604.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Pyrotinib | Pyrotinib, also known as SHR-1258, is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively. Upon oral administration, pyrotinib binds to and inhibits both EGFR and HER2, which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumor cells. Group: Pharmaceutical. Alternative Names: (R,E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-3-(1-methylpyrrolidin-2-yl)acrylamide; Pyrotinib; SHR-1258; SHR1258; SHR 1258; Pyrotinib maleate. CAS No. 1269662-73-8. Pack Sizes: 1 mg. Product ID: B0084-267738. Molecular formula: C32H31ClN6O3. Mole weight: 582.21. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole | (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Uses: Pharmaceutical R&D. Group: Chemicals & Intermediates. CAS No. 112022-81-8. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs). |  UK / EU / USA / Japan |
| Sacubitril Impurity 3 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Group: Pharmaceutical. Alternative Names: (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one; (3S,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one. CAS No. 1038925-00-6. Pack Sizes: 10 mg. Product ID: B2694-479387. Molecular formula: C18H19NO. Mole weight: 265.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Tetrazole 1% solution in N-Methylpyrrolidone | 25ml Pack Size. Group: Building Blocks, Organics. Formula: CH2N4. CAS No. 288-94-8. Prepack ID : 90021909-25ml. Molecular Weight : 70.0534. | |
| Trofinetide | Trofinetide is a NMDA antagonist under the development of Neuren Pharmaceuticals. It is an analogue of the neuropeptide (1-3) IGF-1, which is a simple tripeptide with sequence Gly-Pro-Glu formed by enzymatic cleavage of the growth factor IGF-1 within the brain. Phase II clinical trials against Fragile X syndrome and Rett syndrome are on-going. Uses: Brain injuries; fragile x syndrome; rett syndrome. Group: Pharmaceutical. Alternative Names: NNZ-2566; NNZ 2566; NNZ2566; Trofinetide; ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid. CAS No. 853400-76-7. Pack Sizes: 250 mg. Product ID: B1370-215136. Molecular formula: C13H21N3O6. Mole weight: 315.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Veliparib | Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. In HCT-116 and HT-29 cell lines, the ability of ABT-888 to synergize the effect of the anti-cancer agents, SN38 or oxaliplatin, was determined using the SRB assay. PARP activity was significantly reduced in samples treated with SN38 in combination with ABT-888 (>4 fold at 24 h). Uses: For research used only. Group: Pharmaceutical. Alternative Names: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; ABT888; ABT-888; ABT 888; Veliparib. CAS No. 912444-00-9. Pack Sizes: 250 mg. Product ID: B0084-079466. Molecular formula: C13H16N4O. Mole weight: 244.298. Custom synthesis is available. Send your inquiries for more information. | London |
| Velpatasvir | Velpatasvir is a selective Hepatitis C virus NS 5 protein inhibitor originated by Gilead Sciences. It showed pan-genotypic activity and a high barrier to resistance in HCV replicon assays. Uses: Antiviral agents. Group: Pharmaceutical. Alternative Names: GS5816; GS-5816; GS 5816; Velpatasvir; methyl ((R)-2-((2S,4S)-2-(5-(2-((2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidin-1-yl)-2-oxo-1-phenylethyl)carbamate. CAS No. 1377049-84-7. Pack Sizes: 250 mg. Product ID: B0084-474128. Molecular formula: C49H54N8O8. Mole weight: 883.01. Custom synthesis is available. Send your inquiries for more information. | London |
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