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| Product | Description | |
|---|---|---|
| 2,4-Dichloro-6-methylpyrimidine | 2,4-Dichloro-6-methylpyrimidine Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 5424-21-5. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs). |  UK / EU / USA / Japan |
| 4,6-dichloro-2-methylpyrimidine | 4,6-dichloro-2-methylpyrimidine. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 1780-26-3. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: 1 2-methyl-4. |  Cenik Chemicals |
| 3'-O-(t-Butyldimethylsilyl)thymidine | 3'-O-(t-Butyldimethylsilyl)thymidine, a highly significant compound within the biomedicine sector, plays a pivotal role due to its extensive usage across diverse applications. Notably, this compound serves as a precursor in the synthesis of potent antiviral medications exemplified by AZT, renowned for its efficacy in the treatment of HIV/AIDS. By virtue of its strategic involvement in nucleoside analogue development, this compound emerges as a crucial catalyst, propelling scientific investigations into the combat against viral afflictions and the elucidation of their intricate mechanisms of function. Group: Pharmaceutical. Alternative Names: 3'-O-t-Bulyldimethylsilyl-thymidine; 1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 3'-O-(tert-butyldimethylsilyl)thymidine; Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3'-O-(TBDMS)Thymidine; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]thymidine; 3'-DiTBSRiboT. CAS No. 40733-27-5. Pack Sizes: 10 g. Product ID: B2706-207659. Molecular formula: C16H28N2O5Si. Mole weight: 356.49. Custom synthesis is available. Send your inquiries for more information. |  London |
| 3'-O-(t-Butyldiphenylsilyl)thymidine | 3'- O- (t-Butyldiphenylsilyl)thymidine, a paramount compound in the biomedical sector, finds its application predominantly in the synthesis of nucleic acid analogs and diverse pharmaceutical products. Its indispensability lies in combating an array of ailments such as viral infections and genetic disorders. Group: Pharmaceutical. Alternative Names: ((2R,4S,5R)-4-(tert-butyldiphenylsilyloxy)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 3'-O-t-butyldiphenylsilyl-thymidine; 3'-O-[(2-Methyl-2-propanyl)(diphenyl)silyl]thymidine; Thymidine, 3'-O-[(1,1-dimethylethyl)diphenylsilyl]-; 3'-O-tert-butyldiphenylsilylthymidine. CAS No. 83467-48-5. Pack Sizes: 5 g. Product ID: B2706-283216. Molecular formula: C26H32N2O5Si. Mole weight: 480.63. Custom synthesis is available. Send your inquiries for more information. | London |
| 7'-Hydroxy-N-tritylmorpholino thymine monomer | 7'-Hydroxy-N-tritylmorpholino thymine monomer, a fundamental constituent within the biomedicine realm, assumes paramount importance. Its pivotal function encapsulates nucleic acid analog synthesis, pivotal for scientific inquiry, especially in constructing targeted therapeutic agents against viral infections and select cancer variants. This monomer facilitates the assembly of tailored nucleic acids yielding augmented fortitude, exquisite specificity, and unparalleled efficacy in combating afflictions. Discern its scientific significance and harness its extraordinary potential for transformative outcomes. Group: Pharmaceutical. Alternative Names: 1-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4-(1H,3H)-dione; 7'-OH-N-trityl morpholino thymine; 7-hydroxy-N-trityl morpholinothymidine; 2-hydroxymethyl-4-trityl-6-(thymin-1-yl)morpholine. CAS No. 914361-76-5. Pack Sizes: 100 mg. Product ID: B1370-340310. Molecular formula: C29H29N3O4. Mole weight: 483.56. Custom synthesis is available. Send your inquiries for more information. | London |
| 7'-O-(4,4'-Dimethoxytrityloxy)morpholinothymine | 7'-O-(4,4'-Dimethoxytrityloxy)morpholinothymine is a crucial compound in biomedicine extensively used in the pharmaceutical industry. It exhibits potential as an antiviral drug against herpesviruses and is researched for its promising role in the treatment of various viral infections. Group: Pharmaceutical. Alternative Names: 7'-O-(4,4'-dimethoxytrityl)-5-methylmorpholino uridine; 5'-O-(4,4'-dimethoxytrityl)morpholinothymidine; 1-[(2R,6S)-6-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]morpholin-2-yl]-5-methylpyrimidine-2,4-dione; (2R)-2beta-(5-Methyluracil-1-yl)-6beta-(4,4'-dimethoxytrityloxymethyl)morpholine. CAS No. 143485-05-6. Pack Sizes: 100 mg. Product ID: B1370-094132. Molecular formula: C31H33N3O6. Mole weight: 543.61. Custom synthesis is available. Send your inquiries for more information. | London |
| Abacavir EP Impurity B | Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Pharmaceutical. Alternative Names: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine; O-Pyrimidine derivative abacavir. CAS No. 1443421-69-9. Pack Sizes: 1mg;1g;10g. Product ID: 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Zidovudine | Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo. Uses: Anti-hiv agents; antimetabolites; antimetabolites, antineoplastic; reverse transcriptase inhibitors. Group: Pharmaceutical. Alternative Names: 3'-Azido-3-deoxythymidine; AZT; BWA509U; BWA 509U; BWA-509U; ZDV; Azidothymidine; Retrovir; Timazid; NSC 602670; 3'-Azido-2',3'-dideoxythymidine; 1-(3-Azido-2,3-dideoxy-β-D-glycero-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidin-2,4(1H,3H)-dione; 1-(3-Azido-2,3-dideoxy-β-D-ribofuranosyl)thymine. CAS No. 30516-87-1. Pack Sizes: 100 g. Product ID: NP3476. Molecular formula: C10H13N5O4. Mole weight: 267.24. Custom synthesis is available. Send your inquiries for more information. | London |
| N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide | N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, a potent kinase inhibitor, is prescribed for the management of diverse malignancies such as lung carcinoma and melanoma. Its mechanism of action encompasses the suppression of pivotal pathways implicated in the proliferation and advancement of neoplastic tissues. Group: Pharmaceutical. Alternative Names: 302964-08-5; N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide2-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamideN-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide. CAS No. 302964-08-5. Pack Sizes: 1mg;1g;10g. Product ID: 302964-08-5. Molecular formula: C16H13Cl2N5OS. Mole weight: 394.28. Custom synthesis is available. Send your inquiries for more information. | London |
| Nimustine hydrochloride | Nimustine is a nitrosourea that is used as a DNA alkylating agent for the treatment of malignant glioma. Group: Pharmaceutical. Alternative Names: Nidran hydrochloride; Nimustine HCl; 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride. CAS No. 55661-38-6. Pack Sizes: 1mg;1g;10g. Product ID: 55661-38-6. Molecular formula: C9H13ClN6O2·HCl. Mole weight: 309.15. Custom synthesis is available. Send your inquiries for more information. | London |
| NSC 23766 trihydrochloride | NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Group: Pharmaceutical. Alternative Names: NSC 23766 (trihydrochloride); NSC23766 (trihydrochloride); NSC-23766 (trihydrochloride); N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride. CAS No. 1177865-17-6. Pack Sizes: 25 mg. Product ID: B0084-007260. Molecular formula: C24H38Cl3N7. Mole weight: 530.967. Custom synthesis is available. Send your inquiries for more information. | London |
| PF-5190457 | PF-5190457 is a selective Growth hormone secretagogue receptor inverse agonist and it can increase insulin secretion in glucose-stimulated human islets. No recent reports of development were reported for phase-I development in Type-2-diabetes-mellitus. Uses: Type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: PF-5190457; PF 5190457; PF5190457; PF-05190457; PF05190457; PF 05190457; (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one. CAS No. 1334782-79-4. Pack Sizes: 500 mg. Product ID: B2693-475313. Molecular formula: C29H32N6OS. Mole weight: 512.67. Custom synthesis is available. Send your inquiries for more information. | London |
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