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| Product | Description | |
|---|---|---|
| 4,4'-Azobis(4-cyanopentanol) | 4,4'-Azobis(4-cyanopentanol) (CAS# 4693-47-4 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: 4,4'-Azobis(4-cyano-1-pentanol); 2,2'-(Diazene-1,2-diyl)bis(5-hydroxy-2-methylpentanenitrile); Azopentanon-C. CAS No. 4693-47-4. Pack Sizes: 50 g. Product ID: B2699-069299. Molecular formula: C12H20N4O2. Mole weight: 252.31. Custom synthesis is available. Send your inquiries for more information. |  London |
| Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)- | Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-. Group: Pharmaceutical. Alternative Names: 3-Methoxyperfluoro(2-methylpentane); 1,1,1,2,3,4,4,5,5,5-Decafluoro-3-methoxy-2-(trifluoromethyl)pentane. CAS No. 132182-92-4. Pack Sizes: 500 g. Product ID: B1370-048335. Molecular formula: C7H3F13O. Mole weight: 350.08. Custom synthesis is available. Send your inquiries for more information. | London |
| 2,5-Dioxopyrrolidine Sacubitril | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. Alternative Names: (2R,4S)-5-Biphenyl-4-yl-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester. CAS No. 1038924-97-8. Pack Sizes: 100 mg. Product ID: B1604-479386. Molecular formula: C24H27NO4. Mole weight: 393.483. Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride | An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Group: Pharmaceutical. Alternative Names: 1038924-71-8; (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid;hydrochloride; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride; SCHEMBL597864. CAS No. 1038924-71-8. Pack Sizes: 100 mg. Product ID: B2694-013668. Molecular formula: C18H22ClNO2. Mole weight: 319.8. Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. Alternative Names: 1012341-50-2; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid(2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid; FJ7AWX8DMFUNII-FJ7AWX8DMF. CAS No. 1012341-50-2. Pack Sizes: 100 mg. Product ID: B1604-479394. Molecular formula: C23H29NO4. Mole weight: 383.488. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Hydroxyisoleucine | 4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha. Group: Pharmaceutical. Alternative Names: 4-HYDROXY-L-ISOLEUCINE; (2S,3R)-2-aMino-4-hydroxy-3-Methylpentanoic acid. CAS No. 781658-23-9. Pack Sizes: 100 mg. Product ID: B0005-347850. Molecular formula: C6H13NO3. Mole weight: 147.17. Custom synthesis is available. Send your inquiries for more information. | London |
| 6PPD-quinone | 6PPD-quinone is an oxidized derivative of the tire antiozonant and substituted p-phenylenediamine 6-PPD. It is also an environmental pollutant that can be detected in human urine and is widely present in the environment. Group: Pharmaceutical. Alternative Names: 6-PPD-quinone; 6PPD-Q; 2-((4-Methylpentan-2-yl)amino)-5-(phenylamino)cyclohexa-2,5-diene-1,4-dione; N-(1,3-dimethylbutyl)-N-phenyl-p-phenylenediamine quinone. CAS No. 2754428-18-5. Pack Sizes: 25 mg. Product ID: BB058167. Molecular formula: C18H22N2O2. Mole weight: 298.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Compstatin | Compstatinis, a 13-residue cyclic peptide, is a potent inhibitor of the complement system (IC50= 12 μM) and binds to complement component C3. Group: Pharmaceutical. Alternative Names: H-Ile-Cys(1)-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys(1)-Thr-NH2; L-isoleucyl-L-cysteinyl-L-valyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-tryptophyl-glycyl-L-histidyl-L-histidyl-L-arginyl-L-cysteinyl-L-threoninamide (2->12)-disulfide; 2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-25-(3-amino-3-oxopropyl)-7-[3-(diaminomethylideneamino)propyl]-10,13-bis(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33-decaoxo-28,31-di(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decazacyclopentatriacont-22-yl]acetic acid. CAS No. 206645-99-0. Pack Sizes: 5 mg. Product ID: BAT-006096. Molecular formula: C66H99N23O17S2. Mole weight: 1550.77. Custom synthesis is available. Send your inquiries for more information. | London |
| Diprotin A | It is produced by the strain of Bacillus cereus BMF 657-RF1. It can inhibit Dipeptidyl amino peptidase IV and immune enhancement effect. Group: Pharmaceutical. Alternative Names: Ile-Pro-Ile; isoleucylprolylisoleucine; l-isoleucyl-l-prolyl-l-isoleucine; N-(1-L-Isoleucyl-L-prolyl)-L-isoleucine; isoleucyl-prolyl-isoleucine; L-Isoleucine, N-(1-L-isoleucyl-L-prolyl)-; (2S,3S)-2-((S)-1-((2S,3S)-2-Amino-3-methylpentanoyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid; H-Ile-Pro-Ile-OH. CAS No. 90614-48-5. Pack Sizes: 500 mg. Product ID: BAT-010802. Molecular formula: C17H31N3O4. Mole weight: 341.45. Custom synthesis is available. Send your inquiries for more information. | London |
| DM4-SPDB | DM4 with a reactive linker SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Group: Pharmaceutical. Alternative Names: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2 S)-2-{[4-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}disulfanyl)-4-methylpentanoyl](methyl)amino}propanoate (non-preferred name); DM4 SPDB. CAS No. 1626359-62-3. Pack Sizes: 1 mg. Product ID: BADC-00012. Molecular formula: C46H63ClN4O14S2. Mole weight: 995.59. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Val-Leu-Lys 4-nitroanilide dihydrochloride | D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Group: Pharmaceutical. Alternative Names: (S)-6-Amino-2-((S)-2-((R)-2-amino-3-methylbutanamido)-4-methylpentanamido)-N-(4-nitrophenyl)hexanamide dihydrochloride; H-D-Val-Leu-Lys-pNA 2HCl. CAS No. 62354-43-2. Pack Sizes: 5 mg. Product ID: BAT-014255. Molecular formula: C23H40Cl2N6O5. Mole weight: 551.5. Custom synthesis is available. Send your inquiries for more information. | London |
| GGTI-298 | GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Group: Pharmaceutical. Alternative Names: methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate; GGTI 298; GGTI298; GGTI-298; N-4-[2(R)-Amino-3-mercaptopropyl]amino-2-naphthylbenzoyl-(L)-Leucine methyl ester, TFA; (S)-methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate. CAS No. 180977-44-0. Pack Sizes: 5 mg. Product ID: B0084-272121. Molecular formula: C27H33N3O3S. Mole weight: 479.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Enantiomer | Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Group: Pharmaceutical. Alternative Names: 2R,4S-Sacubitril; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester; 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; (2S,4R)-Sacubitril; SCHEMBL22420467; CS-M3545; AKOS030528367; HY-78847; MS-27102; PD100765; L10003; EN300-6474615; A854860; [1,1'-Biphenyl]-4-pentanoic acid, |A-[(3-carboxy-1-oxopropyl)amino]-|A-methyl-, 4-ethyl ester, (|AS,|AR)-; 3-{[(2R,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester. CAS No. 761373-05-1. Pack Sizes: 25 mg. Product ID: B2694-479381. Molecular formula: C24H29NO5. Mole weight: 411.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Tosedostat | Tosedostat is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2 with IC50 values are > 1000, > 5000, > 10000 and > 30000 nM for aminopeptidase B, PILSAP, LTA4 hydrolase and MetAP2 respectively. Phase 2. Tosedostat potently inhibits tumor cell proliferation in a variety of tumor cell lines in vitro and in vivo. Group: Pharmaceutical. Alternative Names: CHR2797; CHR-2797; CHR 2797; Tosedostat. cyclopentyl (2S)-2-[[(2R)-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl]amino]-2-phenylacetate. CAS No. 238750-77-1. Pack Sizes: 100 mg. Product ID: B0084-088218. Molecular formula: C21H30N2O6. Mole weight: 406.479. Custom synthesis is available. Send your inquiries for more information. | London |
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