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| Product | Description | |
|---|---|---|
| 4-Hydroxyisoleucine | 4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha. Group: Pharmaceutical. Alternative Names: 4-HYDROXY-L-ISOLEUCINE; (2S,3R)-2-aMino-4-hydroxy-3-Methylpentanoic acid. CAS No. 781658-23-9. Pack Sizes: 100 mg. Product ID: B0005-347850. Molecular formula: C6H13NO3. Mole weight: 147.17. Custom synthesis is available. Send your inquiries for more information. |  London |
| 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a potential PPAR agonist with antibacterial, antidiabetic and antioxidant activities. The esteemed 5-[(2,4-Dichlorophenyl)methylidene]-1,3-thiazolidine-2,4-dione is a highly efficacious agent utilized in the management of type 2 diabetes mellitus. By enhancing insulin secretion and suppressing hepatic glucose output, it diligently lowers blood glucose concentrations, thereby promoting normoglycemia. Its demonstrated efficacy and mechanism of action render it an alluring therapeutic option for those with the aforementioned condition. Group: Pharmaceutical. Alternative Names: NSC 31150; Antimicrobial agent-33. CAS No. 51244-45-2. Pack Sizes: 50 mg. Product ID: B0001-284765. Molecular formula: C10H5Cl2NO2S. Mole weight: 274.115. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a chemical compound with potential therapeutic applications in diabetes and related metabolic disorders, exhibits insulin sensitizing properties that are aimed at lowering high-blood glucose levels and enhancing insulin sensitivity. Remarkably, this compound also has antioxidant and anti-inflammatory functions, which manifest its suitability in treating ailments associated with inflammation and oxidative stress. Therefore, it stands a good chance as a candidate for the treatment of various diseases with such pathological features. Group: Pharmaceutical. Alternative Names: 2,4-Thiazolidinedione, 5-[(2-hydroxyphenyl)methylene]-. CAS No. 6325-94-6. Pack Sizes: 50 mg. Product ID: B0001-284762. Molecular formula: C10H7NO3S. Mole weight: 221.23. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(3,4-Dimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(3,4-Dimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a small molecule guanidine compound, exerts hypoglycemic effects in treating diabetes mellitus. The compound's hypoglycemic action is attributed to its capacity to augment insulin sensitivity as well as the uptake of glucose within cellular organelles. Group: Pharmaceutical. Alternative Names: 5-(3,4-dimethoxybenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 6325-95-7. Pack Sizes: 50 mg. Product ID: B0001-284770. Molecular formula: C12H11NO4S. Mole weight: 265.283. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione | 5-(4-Chlorobenzylidene)-2,4-thiazolidinedione, a well-researched organic compound, exhibits remarkable promise in treating diabetes mellitus type 2 owing to its ability to function as an agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ). PPAR-γ is implicated in the modulation of glucose and lipid metabolism. Beyond its anti-diabetic attributes, this compound has been the subject of inquiry for its potential anti-cancer properties. The chemical's therapeutic significance is evidenced by the numerous investigations conducted on its biological activity. Group: Pharmaceutical. Alternative Names: 5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[(4-chlorophenyl)methylene]-. CAS No. 24138-83-8. Pack Sizes: 50 mg. Product ID: B0001-284763. Molecular formula: C10H6ClNO2S. Mole weight: 239.673. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | The compound 5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione finds applications in the biomedical domain as an antidiabetic medication. Its potential as an activator of the peroxisome proliferator-activated receptor gamma (PPARγ) has been acknowledged, presenting a promising approach towards the regulation of glucose metabolism and insulin sensitivity within the body. With demonstrated efficacy in the management of type 2 diabetes mellitus and associated complications, this synthetic compound presents a potential solution to this chronic condition. Group: Pharmaceutical. Alternative Names: Kinome_3045. CAS No. 24044-50-6. Pack Sizes: 50 mg. Product ID: B0001-284767. Molecular formula: C11H9NO4S. Mole weight: 251.256. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[Methylidene]thiazolidine-2,4-dione | 5-[Methylidene]thiazolidine-2,4-dione, a thiazolidinedione derivative, exhibits remarkable pharmaceutical potential in tackling diabetes via targeting the PPAR-γ protein responsible for maintaining glucose homeostasis. The efficacious drug candidate has demonstrated promising outcomes in ameliorating insulin resistance and alleviating hyperglycemia in diverse diabetes animal models, thus rendering it a potential therapeutic agent for diabetes management. Group: Pharmaceutical. Alternative Names: 5-(2-nitrobenzylidene)-1,3-thiazolidine-2,4-dione. CAS No. 36140-65-5. Pack Sizes: 50 mg. Product ID: B0001-284769. Molecular formula: C10H6N2O4S. Mole weight: 250.228. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarbose tridecaacetate | Acarbose tridecaacetate, an alpha-glucosidase inhibitor utilized in managing type 2 diabetes mellitus, enables the delay in carbohydrate digestion and absorption, thus regulating postprandial glucose levels. Group: Pharmaceutical. Alternative Names: O-2,3-Di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-a-D-glucopyranosyl-(1-4)-O-2,3,6-tri-O-acetyl-a-D-glucopyranosyl-(1-4)-a-D-glucopyranose 1,2,3,6-tetraacetate; α-D-Glucopyranose, O-2,3-di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-2,3,6-tri-O-acetyl-α-D-glucopyranosyl-(1→4)-, 1,2,3,6-tetraacetate, [1S-(1α,4α,5β,6α)]-. CAS No. 117065-98-2. Pack Sizes: 1mg;1g;10g. Product ID: 117065-98-2. Molecular formula: C51H69NO31. Mole weight: 1192.08. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. Alternative Names: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. Custom synthesis is available. Send | London |
| Canagliflozin | Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. Group: Pharmaceutical. Alternative Names: D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1S)-; JNJ-24831754; TA-7284; JNJ 24831754; TA 7284; JNJ24831754; TA7284; (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol; (2S,3R,4R,5S,6R)-2-(3-((5-(4-Fluorophenyl)thien-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene; Invokana; JNJ 24831754ZAE; JNJ 28431754AAA. CAS No. 842133-18-0. Pack Sizes: 1 g. Product ID: NP3628. Molecular formula: C24H25FO5S. Mole weight: 444.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Canagliflozin hemihydrate | Canagliflozin hemihydrate is a highly potent and selective inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. It is an experimental drug being developed by Johnson & Johnson for the treatment of type 2 diabetes. Uses: The potential treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: (3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol hemihydrate; JNJ 28431754 hemihydrate; TA 7284 hemihydrate; JNJ-24831754-ZAE hemihydrate; JNJ-28431754-AAA hemihydrate; (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol hydrate (2:1); Cagliflozin hydrate; Invokana hemihydrate; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate. CAS No. 928672-86-0. Pack Sizes: 1 g. Product ID: B0084-463685. Molecular formula: C24H25FO5S.1/2H2O. Mole weight: 453.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin | Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; BMS 512148. CAS No. 461432-26-8. Pack Sizes: 5 g. Product ID: B0084-069214. Molecular formula: C21H25ClO6. Mole weight: 408.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin Furanose Isomer | Dapagliflozin Furanose Isomer is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: Dapagliflozin 1,4-Anhydro impurity; (1S)-1,4-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol. CAS No. 1469910-70-0. Pack Sizes: 100 mg. Product ID: B1370-161656. Molecular formula: C21H25ClO6. Mole weight: 408.87. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin Impurity 16 | Dapagliflozin Impurity 16 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: 1α-Methyl Dapagliflozin; Dapagliflozin Methoxy Pyranose Impurity; (2S,3R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methyl 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-; Methoxy Dapagliflozin. CAS No. 714269-57-5. Pack Sizes: 2.5 g. Product ID: B2694-352556. Molecular formula: C22H27ClO7. Mole weight: 438.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin Impurity 17 | Dapagliflozin Impurity 17 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: 1,4-Dibromo-2-[(4-ethoxyphenyl)methyl]benzene. CAS No. 1807632-93-4. Pack Sizes: 50 mg. Product ID: B2694-352570. Molecular formula: C15H14Br2O. Mole weight: 370.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin Methyl Acetate | Dapagliflozin Methyl Acetate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: Dapagliflozin MonoAcetyl Impurity; ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl acetate. CAS No. 1632287-34-3. Pack Sizes: 100 mg. Product ID: B1370-352565. Molecular formula: C23H27ClO7. Mole weight: 450.91. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin Open Ring | Dapagliflozin Open Ring is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: 1-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; Dapagliflozin Impurity 5 (Mixture of Diastereomers). CAS No. 2100872-88-4. Pack Sizes: 100 mg. Product ID: B1370-352542. Molecular formula: C21H27ClO7. Mole weight: 426.89. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin propanediol hydrate | Dapagliflozin (2S)-1,2-propanediol, hydrate is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Group: Pharmaceutical. Alternative Names: Dapagliflozin (2S)-1,2-propanediol, hydrate; Dapagliflozin propylene glycol hydrate; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1); D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate; Dapagliflozin (S)-propylene glycol hydrate; Dapagliflozin propanediol monohydrate; Edistride; Farxiga; Forxiga; (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (S)-propane-1,2-diol (1:1) monohydrate. CAS No. 960404-48-2. Pack Sizes: 250 mg. Product ID: B0084-463704. Molecular formula: C24H35ClO9. Mole weight: 502.98. Custom synthesis is available. Send your inquiries for more information. | London |
| Dapagliflozin USP Related Compound A | Dapagliflozin Impurity 3 is an impurity of Dapagliflozin. Dapagliflozin (BMS 512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: USP Dapagliflozin Related Compound A; (2S,3R,4R,5S,6R)-2-[4-Bromo-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Dapagliflozin Impurity 3; 4-Deschloro-4-bromo Dapagliflozin; Dapagliflozin 4-bromo Impurity; (1S)-1,5-Anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; D-Glucitol, 1,5-anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-. CAS No. 1807632-95-6. Pack Sizes: 10 mg. Product ID: B2694-469696. Molecular formula: C21H25BrO6. Mole weight: 453.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Ertugliflozin | PF-04971729, a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is developed for the treatment of diabetes mellitus. Inhibitory effects against the organic cation transporter 2-mediated uptake of [14C]metformin by PF-04971729 is very weak (IC50 = 900μM). Uses: Sodium-glucose transporter 2 inhibitors. Group: Pharmaceutical. Alternative Names: PF-04971729; PF 04971729; PF04971729; PF-04971729-00; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose; MK 8835; Steglatro; β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-; 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose; (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. CAS No. 1210344-57-2. Pack Sizes: 100 mg. Product ID: B2693-452980. Molecular formula: C22H25ClO7. Mole weight: 436.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Ginkgolide K | Ginkgolide K is extracted from the leaves of Ginkgo biloba L. It promotes angiogenesis after ischemia stroke and promotes astrocyte migration and proliferation after oxygen-glucose deprivation. It improves nerve injury after cerebral ischemia-reperfusion and inhibits PAF-induced platelet aggregation. It also can promote the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells and shows anti- Parkinson's disease activity. It shows neuroprotective effect and anti-oxidative stress on ischemic stroke. Group: Pharmaceutical. Alternative Names: 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)-2,3,10a,11-tetrahydro-4,11-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aS,10aR,11R,11aR)-. CAS No. 153355-70-5. Pack Sizes: 5 mg. Product ID: NP1526. Molecular formula: C20H22O9. Mole weight: 406.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Glimepiride | Glimepiride is a medium to long-acting sulfonylurea antidiabetic drug. It acts by stimulating the insulin release from pancreatic β-cells and decreases glucose output from the liver. Group: Pharmaceutical. Alternative Names: Amaryl; Glimepirid; Amarel; HOE 490; 1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea. CAS No. 93479-97-1. Pack Sizes: 10 g. Product ID: NP3448. Molecular formula: C24H34N4O5S. Mole weight: 490.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Homoeriodictyol | Homoeriodictyol is a natural compound isolated from the herbs of Taxillus sutchuenensis. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells. Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. Group: Pharmaceutical. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, (2S)-; (2S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, (S)-; Flavanone, 4',5,7-trihydroxy-3'-methoxy-; (-)-Homoeriodictyol; (S)-Homoeriodictyol; 4',5,7-Trihydroxy-3'-methoxyflavanone; 5,7,4'-Trihydroxy-3'-methoxyflavanone; Eriodictyol 3'-methyl ether; Eriodictyonone; Hersperetin. CAS No. 446-71-9. Pack Sizes: 10 mg. Product ID: NP1981. Molecular formula: C16H14O6. Mole weight: 302.28. Custom synthesis is available. Send your inquiries for more information. | London |
| IXA4 | IXA4 is a highly selective and non-toxic IRE1/XBP1s activator, which activates the IRE1/XBP1s signaling, regardless of the global activation of the unfolded protein response (UPR) or other stress-responsive signaling pathways, such as heat shock response or oxidative stress response. IXA4 reduces APP secretion by activating IRE1. IXA4 therapy improves systemic glucose metabolism and hepatic insulin action through IRE1-dependent liver transcriptomic remodeling, thereby reducing glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Group: Pharmaceutical. Alternative Names: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide; 1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-. CAS No. 1185329-96-7. Pack Sizes: 100 mg. Product ID: B1370-382267. Molecular formula: C24H28N4O4. Mole weight: 436.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Kahweol | Kahweol is a natural product isolated from the unsaponifiable fraction of petroleum ether extract of coffee beans. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis. Group: Pharmaceutical. Alternative Names: 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS,5aS,7R,8R,10aR,10bS)-; (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol. CAS No. 6894-43-5. Pack Sizes: 100 mg. Product ID: B1370-148681. Molecular formula: C20H26O3. Mole weight: 314.42. Custom synthesis is available. Send your inquiries for more information. | London |
| KGA2727 | KGA2727 is a selective and potent SGLT1 inhibitor for the treatment of diabete. Its inhibition constant (Ki) values of 97 and 13,600 nM for human (h) SGLT1 and hSGLT2 respectively. It inhibited the absorption of glucose but not that of fructose. Uses: Kga2727 is used for the treatment of diabete. Group: Pharmaceutical. Alternative Names: KGA-2727; KGA 2727; 3-(3-{4-[3-(beta-D-glucopyranosyloxy)-5-isopropyl-1Hpyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)propionamide. CAS No. 666842-36-0. Pack Sizes: 50 mg. Product ID: B2693-476095. Molecular formula: C26H40N4O8. Mole weight: 536.63. Custom synthesis is available. Send your inquiries for more information. | London |
| KL-11743 | KL-11743 is a potent, orally active and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90 and 68 nM for GLUT1, GLUT2, GLUT3 and GLUT4, respectively. It specifically blocks glucose metabolism and induces cell death in concert with electron transport inhibitors. Group: Pharmaceutical. Alternative Names: NSC783733; Acetamide, 2-[3-[6-ethoxy-4-[[4-(1H-pyrazol-4-yl)phenyl]amino]-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-. CAS No. 1369452-53-8. Pack Sizes: 5 mg. Product ID: B2693-381869. Molecular formula: C30H30N6O3. Mole weight: 522.6. Custom synthesis is available. Send your inquiries for more information. | London |
| MBX-2982 | MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. Group: Pharmaceutical. Alternative Names: Pyrimidine, MBX-2982; MBX 2982; MBX2982; SAR-260093; SAR260093; SAR 260093; 5-ethyl-2-(4-(4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-thiazolyl)-1-piperidinyl)-; 4-((4-(1H-tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole; B5TRY67L51. CAS No. 1037792-44-1. Pack Sizes: 20 mg. Product ID: B0084-456604. Molecular formula: C22H24N8OS. Mole weight: 448.549. Custom synthesis is available. Send your inquiries for more information. | London |
| NCT-503 | NCT-503 is a non-competitive phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50= 2.5 μM), reducing the production of glucose-derived serine in cells and suppressing the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors. Group: Pharmaceutical. Alternative Names: NCT-503; NCT 503; NCT503. N-(4,6-dimethylpyridin-2-yl)-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine-1-carbothioamide. CAS No. 1916571-90-8. Pack Sizes: 100 mg. Product ID: B1370-007403. Molecular formula: C20H23F3N4S. Mole weight: 408.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Neferine | Neferine is a bis-benzylisoquinoline alkaloid isolated from the green seed embryos Nelumbo Nucifera Gaertn (Lotus) that displays multiple pharmacological activities including anti-tumor, antidepressant-like and antiarrhythmic actions. It potently inhibits proliferation of human osteosarcoma cells while is low-toxic on non-neoplastic human osteoblast cells. It inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. Group: Pharmaceutical. Alternative Names: 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol; 4''-O-Methylliensinine; Methylliensinine; Phenol,4-[[(1S)-1,2,3,4-tetrahydro-6,7-diMethoxy-2-Methyl-1-isoquinolinyl]Methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-Methoxy-1-[(4-Methoxyphenyl)Methyl]-2-Methyl-7-isoquinolinyl]oxy]-; 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol. CAS No. 2292-16-2. Pack Sizes: 25 mg. Product ID: B2703-464367. Molecular formula: C38H44N2O6. Mole weight: 624.76. Custom synthesis is available. Send your inquiries for more information. | London |
| PF-5190457 | PF-5190457 is a selective Growth hormone secretagogue receptor inverse agonist and it can increase insulin secretion in glucose-stimulated human islets. No recent reports of development were reported for phase-I development in Type-2-diabetes-mellitus. Uses: Type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: PF-5190457; PF 5190457; PF5190457; PF-05190457; PF05190457; PF 05190457; (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one. CAS No. 1334782-79-4. Pack Sizes: 500 mg. Product ID: B2693-475313. Molecular formula: C29H32N6OS. Mole weight: 512.67. Custom synthesis is available. Send your inquiries for more information. | London |
| Pyrroloquinoline quinone disodium salt | The disodium salt form of Pyrroloquinoline quinone which is a cofactor related to the enzyme-catalyzed redox reactions glucose and methanol dehydrogenase. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Methoxatin disodium salt; Methoxatin Disodium; PQQ; Disodium 4,5-dihydro-4,5-dioxo-1H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylate. CAS No. 122628-50-6. Pack Sizes: 1 g. Product ID: BBF-05731. Molecular formula: C14H4N2Na2O8. Mole weight: 374.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Secoisolariciresinol diglucoside | Secoisolariciresinol diglucoside (SDG), a lignan found in flaxseed as well as an emerging source in the functional food area. Flaxseed is the richest source of the lignan secoisolariciresinol diglucoside (SDG). SDG metabolites may protect against CVD and the metabolic syndrome by reducing lipid and glucose concentration, lowering blood pressure, and decreasing oxidative stress and inflammation. Group: Pharmaceutical. Alternative Names: β-D-Glucopyranoside, (2R,3R)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-; (2R,3R)-2,3-Bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-β-D-glucopyranoside; β-D-Glucopyranoside, 2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-, [R-(R*,R*)]-; (R,R)-Secoisolariciresinol diglucoside; SDG; Secoisolariciresinol diglycoside; Secoisolarisiresinol diglucoside; [R-(R*,R*)]-2,3-Bis[(4-Hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl Bis-β-D-glucopyranoside. CAS No. 158932-33-3. Pack Sizes: 100 mg. Product ID: B1370-085032. Molecular formula: C32H46O16. Mole weight: 686.71. Custom synthesis is available. Send your inquiries for more information. | London |
| SR 18292 | SR 18292 is an inhibitor of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α). It reduces blood glucose, potently increases hepatic insulin sensitivity, and improves glucose homeostasis in dietary and genetic mouse models of type 2 diabetes. Group: Pharmaceutical. Alternative Names: 1-[Tert-butyl-[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)propan-2-ol. CAS No. 2095432-55-4. Pack Sizes: 50 mg. Product ID: B2693-292430. Molecular formula: C23H30N2O2. Mole weight: 366.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Tirzepatide | Tirzepatide is a dual GIP and GLP-1 receptor agonist and a drug candidate for the treatment of type 2 diabetes. Uses: Treating type 2 diabetes is one of the main conditions where tirzepatide shows promise. millions of people worldwide suffer with this chronic illness, which is characterized by poor glucose metabolism and insulin resistance. targeting several receptors, such as the glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) receptors, is part of tirzepatide's distinct mo. Group: Pharmaceutical. Alternative Names: L-Tyrosyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methylalanyl-L-leucyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-alanyl-L-glutaminyl-N6-[(22S)-22,42-dicarboxy-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazadotetracont-1-yl]-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-ala. CAS No. 2023788-19-2. Pack Sizes: 100 mg. Product ID: BAT-006246. Molecular formula: C225H348N48O68. Mole weight: 4813.45. Custom synthesis is available. Send your inquiries for more information. | London |
| VER-155008 | VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells. Group: Pharmaceutical. Alternative Names: 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine; C07; VER 155008; VER155008; 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-Adenosine; 4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile. CAS No. 1134156-31-2. Pack Sizes: 100 mg. Product ID: B1370-272446. Molecular formula: C25H23Cl2N7O4. Mole weight: 556.4. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'-O-Methylkurarinone | 2'-O-Methylkurarinone is a dimethoxyflavanone isolated from the roots of Sophora flavescens Ait. It has strong alpha-glucosidase inhibitory activities. Uses: Lethal activity. Group: Pharmaceutical. Alternative Names: (2S)-2'-methoxykurarinone; 2'-Methoxykurarinone; Kurarinone, 2'-O-methyl-. CAS No. 270249-38-2. Pack Sizes: 5 mg. Product ID: NP1992. Molecular formula: C27H32O6. Mole weight: 452.6. Custom synthesis is available. Send your inquiries for more information. | London |
| 3,8-Di-O-methylellagic acid 2-O-glucoside | 3,8-Di-O-methylellagic acid 2-O-glucoside is a natural phenolic compound found in several plants. Group: Pharmaceutical. Alternative Names: 3,3'-Di-O-methylellagic acid 4-O-glucoside. CAS No. 51803-68-0. Pack Sizes: 2 mg. Product ID: NP5079. Molecular formula: C22H20O13. Mole weight: 492.39. Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Methoxyphenyl b-D-glucopyranoside | 4-Methoxyphenyl β-D-glucopyranoside is a naturally occurring compound that has garnered significant attention in the research community due to its potential in suppressing tumor growth and inflammation. Pertinently, animal models have consistently demonstrated its efficacy in inhibiting cancer cell growth and reducing inflammation. Moreover, this compound has shown hopeful prospects in the therapeutic treatment of diabetes and cardiovascular diseases. With its manifold medicinal promises, 4-Methoxyphenyl β-D-glucopyranoside remains a prime target of interest for further research and development. Group: Pharmaceutical. Alternative Names: 4-Methoxyphenyl beta-D-Glucopyranoside; p-Methoxyphenyl b-D-glucoside; 4-Methoxyphenyl b-D-glucopyranoside; (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-methoxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol; methylarbutoside. CAS No. 6032-32-2. Pack Sizes: 5 g. Product ID: B2705-129073. Molecular formula: C13H18O7. Mole weight: 286.28. Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Hydroxymethyl-2-furaldehyde | 5-Hydroxymethylfurfural, found in rhizome of Typhonium giganteum Engl in natural, has antioxidative activity and is therefore used as an acting agent in a novel anticancer infusion solution, named Karal®, and an oral supplementation. Uses: Antioxidative. Group: Pharmaceutical. Alternative Names: Glucosamine EP Impurity E; 5-hydroxy-methylfurfural. CAS No. 67-47-0. Pack Sizes: 1mg;1g;10g. Product ID: NP4241. Molecular formula: C6H6O3. Mole weight: 126.11. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarbose-1-phenylthiol | Acarbose-1-phenylthiol is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites. Group: Pharmaceutical. Alternative Names: (1S,2S,3S,6S)-6-(((2R,3S,4S,5R,6R)-6-(((2R,3S,4R,5R,6R)-6-(((2R,3S,4R,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-methyltetrahydro-2H-pyran-3-yl)amino)-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol; β-D-Glucopyranoside, phenyl O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-1-thio-, [1S-(1α,4α,5β,6α)]-. CAS No. 68107-37-9. Pack Sizes: 1mg;1g;10g. Product ID: 68107-37-9. Molecular formula: C31H47NO17S. Mole weight: 737.77. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarbose-1-phenylthiol Dodecaacetate | Acarbose-1-phenylthiol Dodecaacetate is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites. Group: Pharmaceutical. Alternative Names: (1S,2S,3S,6S)-4-(Acetoxymethyl)-6-(((2R,3R,4S,5R,6R)-4,5-diacetoxy-6-(((2R,3R,4S,5R,6R)-4,5-diacetoxy-2-(acetoxymethyl)-6-(((2R,3R,4S,5R,6S)-4,5-diacetoxy-2-(acetoxymethyl)-6-(phenylthio)tetrahydro-2H-pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl)amino)cyclohex-4-ene-1,2,3-triyl Triacetate; β-D-Glucopyranoside, phenyl O-2,3-di-O-acetyl-4,6-dideoxy-4-[[4,5,6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-2,3,6-tri-O-acetyl-α-D-glucopyranosyl-(1→4)-1-thio-, 2,3,6-triacetate, [1S-(1α,4α,5β,6α)]-. CAS No. 68107-38-0. Pack Sizes: 1mg;1g;10g. Product ID: 68107-38-0. Molecular formula: C55H71NO29S. Mole weight: 1242.21. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether) | Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether) is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites. Group: Pharmaceutical. Alternative Names: (2R,3R,4S,5R,6R)-6-(((2R,3R,4S,5R,6R)-6-(((2R,3R,4S,5R,6S)-4,5-bis((4-Methoxybenzyl)oxy)-2-(((4-methoxybenzyl)oxy)methyl)-6-(phenylthio)tetrahydro-2H-pyran-3-yl)oxy)-4,5-bis((4-methoxybenzyl)oxy)-2-(((4-methoxybenzyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-bis((4-methoxybenzyl)oxy)-2-methyl-N-((1S,4S,5S,6S)-4,5,6-tris((4-methoxybenzyl)oxy)-3-(((4-methoxybenzyl)oxy)methyl)cyclohex-2-en-1-yl)tetrahydro-2H-pyran-3-amine. Pack Sizes: 1mg;1g;10g. Molecular formula: C127H143NO29S. Mole weight: 2179.55. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarbose-N-allyl Formate Tridecaacetate | Acarbose-N-allyl Formate Tridecaacetate is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites. Group: Pharmaceutical. Alternative Names: (3R,4S,5R,6R)-6-(Acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4-diacetoxy-6-(acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4-diacetoxy-5-(((allyloxy)carbonyl)((1S,4S,5S,6S)-4,5,6-triacetoxy-3-(acetoxymethyl)cyclohex-2-en-1-yl)amino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triyl triacetate. Pack Sizes: 1mg;1g;10g. Molecular formula: C55H73NO33. Mole weight: 1276.16. Custom synthesis is available. Send your inquiries for more information. | London |
| Acarviosin | Acarviosin is a potent pharmaceutical compound primarily employed in the research of diabetes and metabolic anomalies, exerting its effects through the remarkable inhibition of the enzymatic activity of alpha-glucosidase. Group: Pharmaceutical. Alternative Names: [1S-(1a,4a,5b,6a)]-4,6-Dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranoside methyl ester; 4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranoside methyl ester. CAS No. 80943-41-5. Pack Sizes: 1mg;1g;10g. Product ID: 80943-41-5. Molecular formula: C14H25NO8. Mole weight: 335.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Ajugol | Ajugol is an iridiod glucoside isolated from the roots of Rehmannia glutinosa. Uses: An iridiod glucoside. Group: Pharmaceutical. Alternative Names: (2S,3S,4R,5R,6S)-2-(hydroxymethyl)-6-{[(4aS,7S,7aR)-7-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl]oxy}tetrahydro-2H-pyran-2,3,4,5-tetrol. CAS No. 52949-83-4. Pack Sizes: 20 mg. Product ID: B1370-138645. Molecular formula: C15H24O9. Mole weight: 348.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Andrographoside | Andrographoside is a natural diterpenoid found in the herbs of Andrographis paniculata. Due to its glucoside groups, andrographiside may act as strong antioxidants. Uses: Antioxidants. Group: Pharmaceutical. Alternative Names: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-5-[(β-D-Glucopyranosyloxy)methyl]decahydro-6-hydroxy-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; 2(3H)-Furanone, 3-[2-[5-[(β-D-glucopyranosyloxy)methyl]decahydro-6-hydroxy-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, [1R-[1α[E(S*)],4aβ,5α,6α,8aα]]-; Andrographiside; Andrographolide 19-O-β-D-glucuronide. CAS No. 82209-76-5. Pack Sizes: 1 mg. Product ID: NP1637. Molecular formula: C26H40O10. Mole weight: 512.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Atractyloside potassium salt | Atractyloside potassium salt is the potassium salt of atractyloside, which inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane. Uses: Inhibitor of the adenine nucleotide translocator (ant). Group: Pharmaceutical. Alternative Names: (2b,4a,15a)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt; Atractylic acid dipotassium salt; Atractylin (C30 glucoside). CAS No. 102130-43-8. Pack Sizes: 20 mg. Product ID: B0005-158965. Molecular formula: C30H44K2O16S2. Mole weight: 802.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Chebulagic acid | Chebulagic acid is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities. It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. And it can also inhibit the production of NO, prostaglandin E2 (PGE2), and reactive oxygen species (ROS), and nuclear translocation of NF-κB in RAW 264.7 macrophages in a concentration-dependent manner. Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Uses: Topoisomerase i inhibitors. Group: Pharmaceutical. Alternative Names: β-D-glucopyranose; Cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate); Cyclic 2→2:4→1-ester with (2S)-2-[(3S,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid. CAS No. 23094-71-5. Pack Sizes: 50 mg. Product ID: B1370-300064. Molecular formula: C41H30O27. Mole weight: 954.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Chrysophanol 1-O-glucoside | Chrysophanol 1-O-glucoside, an inherent component of diverse botanical species, boasts of paramount attention for its noteworthy anti-inflammatory and anti-tumor potentialities that have long been professed in traditional medicine. Its multifaceted pharmacological abilities have been under the researchers' radar, warranting potential deployment in treating metabolic maladies, liver afflictions, and obesity. Besides, this natural compound may stimulate the food and cosmetics industries with its remarkable antioxidant traits. Group: Pharmaceutical. Alternative Names: 8-hydroxy-3-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione; Chrysophanol 1-glucoside. CAS No. 4839-60-5. Pack Sizes: 5 mg. Product ID: NP0916. Molecular formula: C21H20O9. Mole weight: 416.382. Custom synthesis is available. Send your inquiries for more information. | London |
| Diosmetin 7-O-glucoside | Diosmetin 7-O-glucoside is a metabolite of Diosmetin, an O-methylated flavone isolated from Caucasian vetch. Group: Pharmaceutical. Alternative Names: Diosmetol 7-glucoside; 4H-1-Benzopyran-4-one, 7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-. CAS No. 20126-59-4. Pack Sizes: 10 mg. Product ID: NP2499. Molecular formula: C22H22O11. Mole weight: 462.4. Custom synthesis is available. Send your inquiries for more information. | London |
| ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside | ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside is isolated from the herbs of Andrographis paniculata. Group: Pharmaceutical. Alternative Names: 19-O-β-D-glucopyranosyl-ent-labda-8(17),13-dien-15,16,19-triol;ent-Labda-8(17),13Z-diene- 15,16,19-triol 19-O-glucoside;ENT-LABDA-8(17),13Z-DIENE-15,16;β-D-Glucopyranoside, [(1R,4aS,5R,8aS)-decahydro-5-[(3Z)-5-hydroxy-3-(hydroxymethyl)-3-penten-1-yl]-1,4a-dimethyl-6-methylene-1-naphthalenyl]methyl. CAS No. 1245636-01-4. Pack Sizes: 1 mg. Product ID: NP1236. Molecular formula: C26H44O8. Mole weight: 484.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Glucosylisomaltol | Glucosylisomaltol is an indicator for browning reaction. Group: Pharmaceutical. Alternative Names: α-D-Glucopyranosyl isomaltol; 1-[3-(α-D-Glucopyranosyloxy)-2-furanyl]-1-ethanone; 3-O-α-D-Glucopyranosyloxy-2-furyl methyl ketone; 1-[3-(α-D-Glucopyranosyloxy)-2-furanyl]ethanone; 2-Acetylfuran-3-yl-α-D-glucopyranoside; 3-O-a-D-Glucosyl Isomaltol. CAS No. 85559-61-1. Pack Sizes: 25 mg. Product ID: B2699-485024. Molecular formula: C12H16O8. Mole weight: 288.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Isorhamnetin 3-O-glucoside | Isorhamnetin-3-O-beta-D-Glucoside is a glycosyloxyflavone found in many vegetables. Uses: For the prevention and/or treatment of diabetes and its complications. Group: Pharmaceutical. Alternative Names: 3-(β-D-Glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3,4',5,7-tetrahydroxy-3'-methoxy-, 3-β-D-glucopyranoside; Isorhamnetin 3-glucoside; 3,4',5,7-Tetrahydroxy-3'-methoxyflavone 3-β-D-glucopyranoside; 3,5,7,4'-Tetrahydroxy-3'-methoxyflavone 3-β-D-glucoside; 3'-O-Methylquercetin 3-glucoside; 5,7,4'-Trihydroxy-3'-methoxyflavone 3-O-β-glucopyranoside; Isorhamnetin 3-D-glucoside; Isorhamnetin 3-O-β-D-glucopyranoside; Isorhamnetin 3-O-β-D-glucoside; Isorhamnetin 3-O-β-glucoside; Isorhamnetin 3-β-D-glucopyranoside; Isorhamnetin 3-β-D-glucoside. CAS No. 5041-82-7. Pack Sizes: 5 mg. Product ID: NP1954. Molecular formula: C22H22O12. Mole weight: 478.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl 2-acetamido-2-deoxy-a-D-glucopyranoside | Methyl 2-acetamido-2-deoxy-a-D-glucopyranoside is a biomedicine product commonly used in the treatment of various infectious diseases caused by bacteria or viruses. It exhibits antimicrobial properties and functions by inhibiting the growth or replication of these pathogens. This compound can be utilized in the development of pharmaceutical drugs targeting specific pathogens to combat infections and promote better health outcomes. Group: Pharmaceutical. Alternative Names: GlcNAc-a-Ome; Methyl N-acetyl-a-D-glucosamine. CAS No. 6082-4-8. Pack Sizes: 5 g. Product ID: B1370-095470. Molecular formula: C9H17NO6. Mole weight: 235.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl rosmarinate | Methyl rosmarinate is isolated from the herb of Rosmarinus officinalis L. It is a noncompetitive tyrosinase inhibitor with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase. Uses: Antifungal activity. Group: Pharmaceutical. Alternative Names: Methylrosmarinic acid; (+)-Methyl rosmarinate; (R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (E)-3-(3,4-dihydroxyphenyl)acrylate. CAS No. 99353-00-1. Pack Sizes: 5 mg. Product ID: NP3973. Molecular formula: C19H18O8. Mole weight: 374.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Oleuropein | Oleuropein is isolated from the herb of Olea europaea L. It inhibits cell proliferation and induces apoptosis in breast cancer, colorectal cancer and thyroid cancer. Oleuropein also has other functions such as anti-ischemic, antioxidative, anti-inflammatory. It can be used in cosmetics material. Uses: Antioxidant activity; anti-inflammatory agent. Group: Pharmaceutical. Alternative Names: 2H-Pyran-4-acetic acid, 3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, [2S-(2α,3E,4β)]-; 2H-Pyran-4-acetic acid, 5-carboxy-3-ethylidene-2-(β-D-glucosyloxy)-3,4-dihydro-, 3,4-dihydroxyphenethyl 5-methyl ester; 2H-Pyran-4-acetic acid, 3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2S,3E,4S)-; Oleoeuropein; Oleoeuropeine; Oleuropeine; Opiace. CAS No. 32619-42-4. Pack Sizes: 500 mg. Product ID: NP3908. Molecular formula: C25H32O13. Mole weight: 540.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Physcion-1-O-β-D-glucoside | Physcion-1-O-β-D-glucoside is a diterpenoid compound. It is a by-product during the synthesis of Physcion 8-β-D-glucoside. Physcion 8-β-D-glucoside has been studied in research relating to the treatment of the glomerulonephritis. It is the glucoside of Physcion that is a natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew. Group: Pharmaceutical. Alternative Names: 9,10-Anthracenedione, 1-(β-D-glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-; 1-(β-D-Glucopyranosyloxy)-8-hydroxy-6-methoxy-3-methyl-9,10-anthracenedione; Physcionin; 3-Methyl-6-methoxy-1,8-dihydroxyanthraquinone 1-glucoside; Physcion 1-O-β-D-glucopyranoside; Physcion 1-O-β-D-glucoside; Physcion 1-β-D-glucopyranoside. CAS No. 26296-54-8. Pack Sizes: 5 mg. Product ID: B0005-053434. Molecular formula: C22H22O10. Mole weight: 446.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Physcion 8-O-β-D-glucopyranoside | Physcion 8-O-β-D-glucopyranoside is a natural product found in Cortinarius canarius, Saururus chinensis. It is a glycoside of Physcion, a natural anthraquinone derivative, and has an inhibitory effect on the infection process of Blumeria graminis on wheat. It has been used in research to treat glomerulonephritis. Uses: Relating to the treatment of the glomerulonephritis. Group: Pharmaceutical. Alternative Names: Physcion 8-O-glucoside; 1-(β-D-Glucopyranosyloxy)-8-hydroxy-3-methoxy-6-methyl-9,10-anthracenedione; Glucopyranoside, 8-hydroxy-3-methoxy-6-methyl-1-anthraquinonyl, β-D-; Anthraglycoside A; Physcion 8-O-β-D-glucoside; Physcion 8-β-D-glucopyranoside; Physcion-8-β-D-monoglucoside; Physcion 8-β-D-glucoside. CAS No. 23451-01-6. Pack Sizes: 5 mg. Product ID: NP0914. Molecular formula: C22H22O10. Mole weight: 446.4. Custom synthesis is available. Send your inquiries for more information. | London |
| prim-O-Glucosylangelicain | prim-O-Glucosylangelicain is isolated from the roots of Cimicifuga foetida L. Group: Pharmaceutical. Alternative Names: (S)7-[(beta-D-Glucopyranosyloxy)methyl]-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-5H-furo[3,2-g][1]benzopyran-5-one. CAS No. 85889-15-2. Pack Sizes: 1 mg. Product ID: NP4766. Molecular formula: C21H26O11. Mole weight: 454.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside | Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is a remarkable natural compound renowned in the biomedical research.Its perfect value lies in the fact that it has been effectively studied for a wide range of diseases with its powerful antioxidant, anti-inflammatory, anti-tumor and neuroprotective potential. Group: Pharmaceutical. Alternative Names: Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside; quercetin 3-O-beta-D-glucopyranosyl-(1->2)-rhamnopyranoside; 4H-1-Benzopyran-4-one, 3-[(6-deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-; Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranoside; SCHEMBL5086742; CHEBI:66288; DTXSID601105661; HY-N7607; AKOS040763663; MS-30697; PD158845; CS-0134761; Q27134830; 3-(2-O-beta-d-glucopyranosyl-alpha-l-rhamnopyranosyloxy)-3',4',5,7-tetrahydroxyflavone; 3-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one; 3-[(6-Deoxy-2-O-beta-D-glucopyranosyl-alpha-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one. CAS No. 143016-74-4. Pack Sizes: 10 mg. Product ID: B0005-465818. Molecular formula: C27H30O16. Mole weight: 610.5. Custom synthesis is available. Send your i | London |
| Rhodiocyanoside A | Rhodiocyanoside A is a cyanogenic glucoside found in the Rhodiola quadrifida with inhibitory activity against histamine. Group: Pharmaceutical. Alternative Names: (2Z)-4-(beta-D-glucopyranosyloxy)-2-methylbut-2-enenitrile; (2Z)-2-methyl-4-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}but-2-enenitrile. CAS No. 168433-86-1. Pack Sizes: 5 mg. Product ID: B0005-053371. Molecular formula: C11H17NO6. Mole weight: 259.258. Custom synthesis is available. Send your inquiries for more information. | London |
| Steviol | Steviol is a diterpenoiic carboxylic alcohol and is isolated from the herbs of Stevia rebaudiana. It is the aglycon derivative of natural sweetener steviol glycosides and is found to be highly mutagenic compared to Stevioside. It inhibits the proliferation of the gastrointestinal cancer cells and the human osteosarcoma U2OS cell line in a dose- and time-dependent manner. It also inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4. It increases CYP3A29 expression and enhances pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity. It can be used to treat polycystic kidney disease. It can promote proteasome and lysosome-mediated AQP2 degradation and slow cyst growth by reducing AQP2 transcription. Group: Pharmaceutical. Alternative Names: (4α)-13-Hydroxy-kaur-16-en-18-oic Acid; 13-Hydroxy-kaur-16-en-18-oic Acid; 13-Hydroxykaurenoic Acid; Ent-13-hydroxy-kauran-16-en-19-oic Acid; 1H-2,10a-Ethanophenanthrene; 13-O-Glucosylsteviol; Hydroxydehydrostevic Acid; (4R,4aS,6aR,9S,11aR,11bS)-9-hydroxy-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid. CAS No. 471-80-7. Pack Sizes: 20 mg. Product ID: NP1541. Molecular formula: C20H30O3. Mole weight: 318.45. Custom synthesis is available. Send your inquiries for more information | London |
| Streptozotocin | Streptozotocin is a monosaccharide antibiotic produced by Str. achromogenes 128 (NRRL 2697). It has antibacterial effect, and human serum and urine do not affect its activity. It can protect mice infected with Staphylococcus aureus, Pasteurella pestis and Proteus vulgaris. The same amount of antibiotic U-15774 can inhibit mouse sarcoma-180, sarcoma L5178Y, Walker-256 and Ehrlich carcinoma. Streptozotocin is a glucosamine-nitrosourea derivative, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. It is commonly used for the treatment of metastatic pancreatic islet cell carcinoma. Uses: The treatment of metastatic pancreatic islet cell carcinoma. Group: Pharmaceutical. Alternative Names: streptozosin; Estreptozocina. CAS No. 18883-66-4. Pack Sizes: 1 g. Product ID: BBF-03488. Molecular formula: C8H15N3O7. Mole weight: 265.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Sulforaphane | Sulforaphaneis a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale. Uses: Anti-inflammatory/antitumor. Group: Pharmaceutical. Alternative Names: 4-Methylsulfinylbutyl Isothiocyanate; Sulforaphan; DL-Sulforaphane; Butane, 1-isothiocyanato-4-(methylsulfinyl)-; (±)-sulforaphane; 4-Isothiocyanatobutyl methyl sulfoxide. CAS No. 4478-93-7. Pack Sizes: 1 g. Product ID: NP4355. Molecular formula: C6H11NOS2. Mole weight: 177.28. Custom synthesis is available. Send your inquiries for more information. | London |
| Swertisin | Swertisin efficiently changed the morphology of NIH3T3 cells from fibroblastic to round aggregate cell cluster in huge numbers. Dithizone (DTZ) stain primarily confirmed differentiation and gene expression studies signified rapid onset of differentiation signaling cascade in Swertisin-induced ILCC. Group: Pharmaceutical. Alternative Names: Flavocommelitin; 6-C-glucopyranosyl-7-O-methylapigenin; Apigenin 6-glucosyl-7-O-methyl ether. CAS No. 6991-10-2. Pack Sizes: 5 mg. Product ID: B2703-199278. Molecular formula: C22H22O10. Mole weight: 446.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Thiocolchicoside | Thiocolchicoside is a semi-synthetic derivative of colchicine, an anti-inflammatory glycoside extracted from the flower seeds of superba gloriosa. Thiocolchicoside acts as a GABAA receptor antagonist exhibiting anti-inflammatory and analgesic activity. It is used as a muscle relaxant. Group: Pharmaceutical. Alternative Names: N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; Coltramyl; Coltrax; Miorel; Miotens; Muscoril; Colchicoside, 10-thio-; 2-Demethoxy-2-glucosidoxythiocolchicine; Etoshine MR; NSC 147755; R 271; Thiocholshikoside. CAS No. 602-41-5. Pack Sizes: 500 mg. Product ID: B0084-464811. Molecular formula: C27H33NO10S. Mole weight: 563.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Group: Pharmaceutical. Alternative Names: 7-Acetyl-8-hydroxy-3-methoxy-6-methyl-1-naphthyl β-D-glucopyranos ide. CAS No. 64032-49-1. Pack Sizes: 10 mg. Product ID: NP5145. Molecular formula: C20H24O9. Mole weight: 408.4. Custom synthesis is available. Send your inquiries for more information. | London |
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