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| Product | Description | |
|---|---|---|
| Methyl formate | 500ml Pack Size. Group: Analytical Reagents, Building Blocks, Organics, Solvents. Formula: C2H4O2. CAS No. 107-31-3. Prepack ID : 90028595-500ml. Molecular Weight : 60.05. |  |
| 3-Mercapto-3-methylbutyl-Formate-[d6] | 3-Mercapto-3-methylbutyl-Formate-[d6]. Group: Pharmaceutical. Alternative Names: 3-Mercapto-3-methylbutyl-d6 Formate; 3-Mercapto-3-methyl-1-butanol-d6 1-Formate. CAS No. 162404-32-2. Pack Sizes: 10 mg. Product ID: BLP-002765. Molecular formula: C6H6D6O2S. Mole weight: 154.26. Custom synthesis is available. Send your inquiries for more information. |  London |
| Acarbose-N-allyl Formate Tridecaacetate | Acarbose-N-allyl Formate Tridecaacetate is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites. Group: Pharmaceutical. Alternative Names: (3R,4S,5R,6R)-6-(Acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4-diacetoxy-6-(acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4-diacetoxy-5-(((allyloxy)carbonyl)((1S,4S,5S,6S)-4,5,6-triacetoxy-3-(acetoxymethyl)cyclohex-2-en-1-yl)amino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triyl triacetate. Pack Sizes: 1mg;1g;10g. Molecular formula: C55H73NO33. Mole weight: 1276.16. Custom synthesis is available. Send your inquiries for more information. | London |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Group: Pharmaceutical. Alternative Names: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. CAS No. 861393-28-4. Pack Sizes: 1mg;1g;10g. Product ID: 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. Custom synthesis is available. Send your inquiries for more information. | London |
| BAY 41-4109 | BAY 41-4109 is a novel drug inhibiting hepatitis B virus capsid formation and replication. Group: Pharmaceutical. Alternative Names: BAY-41-4109; BAY41-4109; BAY 41-4109; BAY-414109; BAY414109; BAY 414109. methyl (4R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate. CAS No. 298708-81-3. Pack Sizes: 2 mg. Product ID: B0084-475623. Molecular formula: C18H13ClF3N3O2. Mole weight: 395.766. Custom synthesis is available. Send your inquiries for more information. | London |
| Blasticidin S Hydrochloride | Blasticidin S HCl is a nucleoside antibiotic that is first isolated from Streptomyces griseochromogenes. Blasticidin S inhibits protein synthesis in both prokaryotic and eukaryotic cells via suppressing peptide bond formation by the ribosome. Uses: Antibiotic that inhibits protein synthesis. Group: Pharmaceutical. Alternative Names: (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride; 4-Phenyl-3-propan-2-ylhept-1-en-5-yn-4-ol. CAS No. 3513-3-9. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04056. Molecular formula: C17H26N8O5.HCl. Mole weight: 458.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Brandioside | Brandioside is found in the herbs of Verbena officinalis. Brandioside exhibits inhibitory effect on advanced glycation end product formation and smooth muscle cell proliferation. Group: Pharmaceutical. Alternative Names: 2'-O-Acetylpoliumoside; [5-acetyloxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate. CAS No. 133393-81-4. Pack Sizes: 5 mg. Product ID: B0005-053779. Molecular formula: C37H48O20. Mole weight: 812.771. Custom synthesis is available. Send your inquiries for more information. | London |
| Brassicasterol | A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. Brassicasterol can increase accumulation of demosterol, a cholesterol precursor and substrate and inhibit cholesterol formation in HL-60 cells in a dose-dependent manner. It also inhibits the hemolytic activity of pneumolysin from S. pneumoniae. Group: Pharmaceutical. Alternative Names: (3β,22E)-Ergosta-5,22-dien-3-ol; 24-Methylcholesta-5,22-dien-3β-ol; Brassicasterin; Ergosta-5,22(E)-dien-3β-ol. CAS No. 474-67-9. Pack Sizes: 5 mg. Product ID: B1370-023362. Molecular formula: C28H46O. Mole weight: 398.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Cidofovir | Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. Group: Pharmaceutical. Alternative Names: Vistide; HPMPC; (S)-HPMPC; Cidofovir anhydrous; GS-504; GS 504; GS504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; (S)-(((1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid. CAS No. 113852-37-2. Pack Sizes: 1 g. Product ID: B2693-054919. Molecular formula: C8H14N3O6P. Mole weight: 279.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Clomesone | Clomesone is a chloroethylating agent that induces the formation of cross-links between DNA strands in some cell lines and has shown antitumor activity in some animal models. It is a drug commonly used to treat female infertility and works by blocking the action of estrogen in the brain. It has been shown to be effective in inducing ovulation in women with polycystic ovary syndrome and other infertility conditions. Group: Pharmaceutical. Alternative Names: Methanesulfonic acid, 1-(methylsulfonyl)-, 2-chloroethyl ester; 2-Chloroethyl 1-(methylsulfonyl)methanesulfonate; Methanesulfonic acid, (methylsulfonyl)-, 2-chloroethyl ester; 2-Chloroethyl methanesulfonylmethanesulfonate; Chlorethyl SOSO; NSC 338947. CAS No. 88343-72-0. Pack Sizes: 1mg;1g;10g. Product ID: 88343-72-0. Molecular formula: C4H9ClO5S2. Mole weight: 236.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Cyanocobalamin Impurity G | Cyanocobalamin Impurity G is a Vitamin B12 derivative, a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Group: Pharmaceutical. Alternative Names: Nb-methyl-Cobinamide Cyanide 3'-Ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole Dihydrogen Phosphate (Ester), Inner Salt; 34-Methylcyanocobalamin; Cyanocobalamin Impurity G; Nb-Methyl Cyancobalamin. CAS No. 38218-51-8. Pack Sizes: 2.5 mg. Product ID: B2694-469494. Molecular formula: C64H90CoN14O14P. Mole weight: 1369.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Cyclosporin H | The minor analogues of the cyclosporin family have immunological activity because they do not bind to immunophilins. It is an inhibitor of phorbol ester that effectively promotes tumors on mouse skin, and effectively inhibits calcium/calmodulin-dependent phosphorylation of EF-2 in vitro. It is an effective and selective formyl peptide receptor antagonist and formyl peptide-induced superoxide formation inhibitor. Group: Pharmaceutical. Alternative Names: 5-(N-methyl-D-valine)cyclosporine A. CAS No. 83602-39-5. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05764. Molecular formula: C62H111N11O12. Mole weight: 1202.61. Custom synthesis is available. Send your inquiries for more information. | London |
| CZ415 | CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Group: Pharmaceutical. Alternative Names: CZ415; CZ-415; CZ 415; (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea. CAS No. 1429639-50-8. Pack Sizes: 5 mg. Product ID: B0084-474821. Molecular formula: C22H29N5O4S. Mole weight: 459.57. Custom synthesis is available. Send your inquiries for more information. | London |
| δ-Tocotrienol | δ-Tocotrienol is from palm oil. Delta-tocotrienol is a potential angiogenic inhibitor that significantly suppresses human colorectal adenocarcinoma cells (DLD-1-CM)-induced tube formation, migration, and adhesion on human umbilical vein endothelial cells. Delta-tocotrienol is a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offer a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects that protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. Group: Pharmaceutical. Alternative Names: [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,8-Dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (R)-δ-Tocotrienol; 8-Methyltocotrienol; d-δ-Tocotrienol. CAS No. 25612-59-3. Pack Sizes: 50 mg. Product ID: NP4617. Molecular formula: C27H40O2. Mole weight: 396.6. Custom synthesis is available. Send your inquiries for more information. | London |
| EC330 | EC330 is a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range, blocked formation of colonies in soft agar and inhibited angiogenesis (tube formation) in HUVEC cells. EC330 as a novel LIF inhibitor has targeted therapeutic perspectives for patients with aggressive primary tumors. Group: Pharmaceutical. Alternative Names: EC330; EC 330; EC-330; (8S,11R,13S,14S,17S)-11-(4-cyclopropylphenyl)-17-(1,1-difluoroprop-2-ynyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one. CAS No. 2016795-77-8. Pack Sizes: 5 mg. Product ID: B0084-007323. Molecular formula: C30H32F2O2. Mole weight: 462.57. Custom synthesis is available. Send your inquiries for more information. | London |
| EUK 134 | EUK-134 is a unique small molecule antioxidant and anti-aging active substance with excellent antioxidant properties. It possesses the dual effects of superoxide dismutase SOD and catalase CAT, effectively improving cell damage caused by oxidative stress, and inhibiting the formation of β-amyloid protein and related amyloid protein fibers. The EUK-134 facilitates the penetration and absorption of the skin surface, enabling direct entry into the skin to exert its effects and optimize its potent efficacy. Essentially functioning as a catalyst, it remains unaffected by the number of reactions, allowing for reusability with minimal quantity while maintaining stability in nature. It can be used in anti-aging products, sunscreen products, whitening products and skin repair products. Group: Pharmaceutical. Alternative Names: Manganese, chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]-, (SP-5-13)-; (SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]manganese; Manganese, chloro[[2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxyphenolato]](2-)-N2,N2',O1,O1']-; Phenol, 2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxy-. CAS No. 81065-76-1. Pack Sizes: 100 mg. Product ID: B2693-098846. Molecular formula: C18H18ClMnN2O4. Mole weight: 416.74. Custom synthesis is available. Send your inquiries for more informatio | London |
| Linezolid Impurity 44 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Group: Pharmaceutical. Alternative Names: N-[(2S)oxiranylmethyl]acetamide; Acetamide, N-[(2S)-oxiranylmethyl]-; N-[[(2S)-oxiran-2-yl]methyl]acetamide; (S)-(+)-N-(oxiranylMethyl)acetaMide; (S)-N-oxiranylmethyl-acetamide; SCHEMBL2863034; (s)-n-(oxiranylmethyl)acetamide; DTXSID80453297; HBTVZPMDLRPWKZ-YFKPBYRVSA-N; N-[(2S)oxiranylmethyl] acetamide; (S)-N-(Oxiran-2-ylmethyl)acetamide; CS-0166034; (S)-N-(oxiran-2-ylmethyl)acetamide? (Brexpiprazole Impurity pound(c). CAS No. 183805-10-9. Pack Sizes: 2 mg. Product ID: B2694-338787. Molecular formula: C5H9NO2. Mole weight: 115.13. Custom synthesis is available. Send your inquiries for more information. | London |
| Potassium (4-methoxy)benzyloxymethyltrifluoroborate | Alkoxymethyltrifluoroborate undergoes palladium-catalyzed carbon-carbon bond formation (Suzuki-Miyuara reaction) with aryl chlorides to provide a non-traditional disconnection for the preparation of aryl- and heteroaryl ethers. Group: Pharmaceutical. Alternative Names: Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate. CAS No. 1027642-26-7. Pack Sizes: 5 g. Product ID: B2699-303740. Molecular formula: C9H11BF3KO2. Mole weight: 258.087. Custom synthesis is available. Send your inquiries for more information. | London |
| Procyanidin B2 | Procyanidin B2 has been shown to inhibit the formation of the advanced glycation end-products pentosidine, carboxymethyllysine (CML), and methylglyoxal (MGO). Uses: Anti-hypertension. Group: Pharmaceutical. Alternative Names: PROCYANIDIN B2; 4,8'-BI-[(+)-EPICATECHIN]; EPICATECHIN(4BETA->8)EPICATECHIN; EPICATECHIN(4B-8)EPICATECHIN; CIS,CIS'-4,8'-BI(3,3',4',5,7-PENTAHYDROXYFLAVANE); 4,8-Bi-2H-1-benzopyran-3,3,5,5,7,7-hexol, 2,2-bis(3,4-dihydroxyphenyl)-3,3,4,4-tetrahydro-, (2R,2R,3R,3R,4R)-; PROCYANIDIN B2(RG); PROCYANIDINDIMERB2. CAS No. 29106-49-8. Pack Sizes: 10 mg. Product ID: NP1984. Molecular formula: C30H26O12. Mole weight: 578.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Smad3 Inhibitor, SIS3 | Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Group: Pharmaceutical. Alternative Names: 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. CAS No. 1009104-85-1. Pack Sizes: 25 mg. Product ID: B0084-310534. Molecular formula: C28H27N3O3. Mole weight: 453.542. Custom synthesis is available. Send your inquiries for more information. | London |
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