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| Product | Description | |
|---|---|---|
| Methanesulfonamide | Methanesulfonamide is used in biological studies to predict binding affinity and binding mode of protein ligand complexes. Group: Pharmaceutical. Alternative Names: Methylsulfonamide; Methanesulphonamide; Methane sulfonamide. CAS No. 3144-09-0. Pack Sizes: 1 kg. Product ID: B1370-313027. Molecular formula: CH5NO2S. Mole weight: 95.12. Custom synthesis is available. Send your inquiries for more information. |  London |
| A 61603 hydrobromide | A 61603 hydrobromide is a potent and selective α-adrenoceptor agonist with 35-fold selectivity for α1A over α1B or α1D sites. Activation of the α1A-adrenergic receptor by A 61603 induces dose response increases in spontaneous Ca2+ transients in rat ventricular myocytes in vitro (EC50 = 6.9 nmol/L). Group: Pharmaceutical. Alternative Names: A61603 Hydrobromide; A 61603 Hydrobromide; A-61603 Hydrobromide; N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide hydrobromide. CAS No. 107756-30-9. Pack Sizes: 1mg;1g;10g. Product ID: 107756-30-9. Molecular formula: C14H19N3O3S.HBr. Mole weight: 390.29. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-072 | ABT-072 is a potent and orally active non-nucleoside HCV NS5B polymerase inhibitor with EC50s of 1 nM and 0.3 nM for HCV GT1a and HCV GT1b, respectively. Group: Pharmaceutical. Alternative Names: (E)-N-(4-(3-(tert-Butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide; Methanesulfonamide, N-[4-[(1E)-2-[5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-(1,1-dimethylethyl)-2-methoxyphenyl]ethenyl]phenyl]-; N-(4-{(E)-2-[5-(2,4-Dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2-methoxy-3-(2-methyl-2-propanyl)phenyl]vinyl}phenyl)methanesulfonamide. CAS No. 1132936-00-5. Pack Sizes: 1mg;1g;10g. Product ID: 1132936-00-5. Molecular formula: C24H27N3O5S. Mole weight: 469.55. Custom synthesis is available. Send your inquiries for more information. | London |
| ABT-072 potassium trihydrate | ABT-072 potassium trihydrate is a potent and orally active non-nucleoside HCV NS5B polymerase inhibitor with EC50s of 1 nM and 0.3 nM for HCV GT1a and HCV GT1b, respectively. Group: Pharmaceutical. Alternative Names: Methanesulfonamide, N-(4-((1E)-2-(5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-(1,1-dimethylethyl)-2-methoxyphenyl)ethenyl)phenyl)-, potassium salt, hydrate (1:1:3); (E)-N-(4-(3-(tert-Butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide potassium salt trihydrate. CAS No. 1132940-31-8. Pack Sizes: 1mg;1g;10g. Product ID: 1132940-31-8. Molecular formula: C24H32KN3O8S. Mole weight: 561.69. Custom synthesis is available. Send your inquiries for more information. | London |
| dasabuvir | Dasabuvir is an antiviral drug for the treatment of hepatitis C. It inhibits hepatitis C virus (HCV) non-nucleoside NS5B palm polymerase to suppress RNA replicase. Dasabuvir is commonly used in combination with ombitasvir/paritaprevir/ritonavir to effect on HCV type 1. Uses: The treatment of hepatitis c. Group: Pharmaceutical. Alternative Names: ABT333; ABT-333; ABT 333, Dasabuvir. Trade names: Viekira Pak (with ombitasvir/paritaprevir/ritonavir tablets), Exviera; N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide. CAS No. 1132935-63-7. Pack Sizes: 100 mg. Product ID: B0084-462255. Molecular formula: C26H27N3O5S. Mole weight: 493.578. Custom synthesis is available. Send your inquiries for more information. | London |
| Deoxysotalol hydrochloride | An impurity of Sotalol. Sotalol is a non-selective competitive beta-adrenergic receptor blocker that also exhibits Class III antiarrhythmic properties. Group: Pharmaceutical. Alternative Names: Sotalol EP Impurity A Hydrochloride; Sotalol USP Related Comopound C; Deshydroxy Sotalol Hydrochloride; N-(4-(2-((1-Methylethyl)amino)ethyl)phenyl)methanesulfonamide monohydrochloride. CAS No. 16974-44-0. Pack Sizes: 50 mg. Product ID: B1370-275368. Molecular formula: C12H21ClN2O2S. Mole weight: 292.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Dronedarone-[d6] Hydrochloride | Dronedarone-[d6] HCl is a labelled analogue of Dronedarone. Dronedarone is a medication used to treat atrial fibrillation and atrial flutter. Group: Pharmaceutical. Alternative Names: N-[2-Butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide-d6 Hydrochloride; SR33589-d6 Hydrochloride; Multaq-d6 Hydrochloride. CAS No. 1329809-23-5. Pack Sizes: 5 mg. Product ID: BLP-013100. Molecular formula: C31H39D6ClN2O5S. Mole weight: 599.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Dronedarone hydrochloride | Dronedarone HCl is a therapy for the treatment of patients with paroxysmal and persistent atrial fibrillation or atrial flutter. Group: Pharmaceutical. Alternative Names: N-[2-Butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide Hydrochloride; SR33589 Hydrochloride; Multaq Hydrochloride. CAS No. 141625-93-6. Pack Sizes: 1mg;1g;10g. Product ID: NP3370. Molecular formula: C31H44N2O5S.HCl. Mole weight: 593.22. Custom synthesis is available. Send your inquiries for more information. | London |
| E-4031 | E-4031, a benzenesulfonamide derivative, could be used as a Class III antiarrhythmic agent due to its effect of blocking the ERG potassium channels. Uses: E-4031 could be used as a class iii antiarrhythmic agent due to its effect of blocking the erg potassium channels. Group: Pharmaceutical. Alternative Names: E-4031; E 4031; E4031; 113559-13-0;CHEMBL536480;E-4031dihydrochloride;E-4031;1-(2-(6-Methyl-2-pyridyl)ethyl)-4-(4-methylsulfonylaminobenzoyl)piperidinedihydrochloride;N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamidedihydrochloride. CAS No. 113559-13-0. Pack Sizes: 25 mg. Product ID: B2693-338550. Molecular formula: C21H29Cl2N3O3S. Mole weight: 474.44. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Dofetilide | N-Desmethyldofetilide is a derivative of Dofetilide. Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug. Group: Pharmaceutical. Alternative Names: Dofetilide USP Related Compound A; Dofetilide Impurity 1; Methanesulfonamide, N-[4-[2-[[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]-; N-(4-(2-((4-(Methylsulfonamido)phenethyl)amino)ethoxy)phenyl)methanesulfonamide. CAS No. 176447-94-2. Pack Sizes: 50 mg. Product ID: B1370-165790. Molecular formula: C18H25N3O5S2. Mole weight: 427.54. Custom synthesis is available. Send your inquiries for more information. | London |
| Nimesulide Impurity E | An impurity of Nimesulide, which is a selective COX-7 inhibitor. Group: Pharmaceutical. Alternative Names: N-(Methylsulfonyl)-4-(desnitro) Nimesulide; N-(Methylsulfonyl)-N-(2-phenoxyphenyl)methanesulfonamide. CAS No. 905858-63-1. Pack Sizes: 10 mg. Product ID: B0159-478173. Molecular formula: C14H15NO5S2. Mole weight: 341.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Nimesulide Impurity F | An impurity of Nimesulide, which is a selective COX-5 inhibitor. Group: Pharmaceutical. Alternative Names: N-Methylsulfonyl Nimesulide; N-(Methylsulfonyl)-N-(4-nitro-2-phenoxyphenyl)methanesulfonamide; N-(Methylsulfonyl)-4'-nitro-2'-phenoxymethanesulfonanilide. CAS No. 51765-72-1. Pack Sizes: 100 mg. Product ID: B0159-478172. Molecular formula: C14H14N2O7S2. Mole weight: 386.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Oclacitinib maleate | Oclacitinib maleate was the first selective Janus kinase (JAK) inhibitor to be developed for dogs. Oclacitinib is most potent at inhibiting JAK1 (IC50=10 nM). Group: Pharmaceutical. Alternative Names: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-, (2Z)-2-butenedioate (1:x); Apoquel; Oclacitinib maleate (1:x); PF 03394197-11; trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanemethanesulfonamide maleate (1:x); N-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide maleate. CAS No. 1208319-27-0. Pack Sizes: 10 g. Product ID: B1370-007675. Molecular formula: C15H23N5O2S.xC4H4O4. Mole weight: 337.44 (free base). Custom synthesis is available. Send your inquiries for more information. | London |
| Oclacitinib monomaleate | Oclacitinib, also called as PF-03394197, is a novel inhibitor of JAK family members (IC50 = 10 - 99 nM) and JAK1-dependent cytokines involved in allergy, inflammation, and pruritus (IC50 = 36 - 249 nM), without affecting a panel of 38 non-JAK kinases. It could reduce pruritus and associated inflammatory skin lesions in dogs with AD. Group: Pharmaceutical. Alternative Names: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-, (2Z)-2-butenedioate (1:1); trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanemethanesulfonamide maleate (1:1); N-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide monomaleate. CAS No. 1640292-55-2. Pack Sizes: 50 mg. Product ID: B2693-008142. Molecular formula: C15H23N5O2S.C4H4O4. Mole weight: 453.51. Custom synthesis is available. Send your inquiries for more information. | London |
| Presatovir | Presatovir is a viral fusion protein inhibitor with EC50 value of 0.43 nM. It can inhibit a broad range of respiratory syncytial virus clinical isolates by blocking the virus-cell fusion process. It can also inhibit pre- to post-fusion conformational changes of the respiratory syncytial virus fusion protein. Phase II clinical trials for the treatment of respiratory syncytial virus infections is ongoing. Group: Pharmaceutical. Alternative Names: N-(2-((S)-2-(5-((S)-3-aminopyrrolidin-1-yl)-6-methylpyrazolo[1,5-a]pyrimidin-2-yl)piperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide; GS-5806; GS5806; GS 5806. CAS No. 1353625-73-6. Pack Sizes: 5 mg. Product ID: B0084-475346. Molecular formula: C24H30ClN7O3S. Mole weight: 532.06. Custom synthesis is available. Send your inquiries for more information. | London |
| Rosuvastatin EP Impurity D | Rosuvastatin EP Impurity D is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Group: Pharmaceutical. Alternative Names: Rosuvastatin Calcium EP Impurity D; N-(4-(4-Fluorophenyl)-5-((E)-2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)vinyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide; N-[4-(4-Fluorophenyl)-5-[(1E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethen-1-yl]-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide; N-[4-(4-Fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethenyl]-6-(1-methylethyl)-pyrimidin-2-yl]-N-methylmethanesulfonamide; Rosuvastatin Lactone; Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-; N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide; Rosuvastatin-5S-lactone. CAS No. 503610-43-3. Pack Sizes: 10 mg. Product ID: B0194-069823. Molecular formula: C22H26FN3O5S. Mole weight: 463.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Sumatriptan succinate | Sumatriptan Succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches. Uses: Vasoconstrictor agents. Group: Pharmaceutical. Alternative Names: Imigran; Imitrex; Sumitrex; Arcoiran; GR 43175; GR43175; GR-4317; 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide Succinate. CAS No. 103628-48-4. Pack Sizes: 1 g. Product ID: B1370-053376. Molecular formula: C18H27N3O6S. Mole weight: 413.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Zonisamide | Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Uses: Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive t-type calcium currents. heterocyclic methanesulfonide with anticonvulsant properties. the compound is under investigation for potent. Group: Pharmaceutical. Alternative Names: AD-810; AD-810N; AD 810; AD 810N; AD810; AD810N; 1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole. CAS No. 68291-97-4. Pack Sizes: 1 g. Product ID: B0084-075118. Molecular formula: C8H8N2O3S. Mole weight: 212.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Encorafenib | Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Group: Pharmaceutical. Alternative Names: LGX818; LGX-818; LGX 818; Methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate. CAS No. 1269440-17-6. Pack Sizes: 150 mg. Product ID: B0084-462563. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.011. Custom synthesis is available. Send your inquiries for more information. | London |
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