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| Product | Description | |
|---|---|---|
| Melphalan EP Impurity D | Melphalan EP Impurity D is an impurity of Melphalan which is an antineoplastic. Group: Pharmaceutical. Alternative Names: Hydroxymelphalan; Monohydroxymelphalan; Monohydroxy melphalan; 4-[(2-Chloroethyl)(2-hydroxyethyl)amino]-L-phenylalanine; (S)-2-Amino-3-(4-((2-chloroethyl)(2-hydroxyethyl)amino)phenyl)propanoic Acid. CAS No. 61733-01-5. Pack Sizes: 25 mg. Product ID: B1370-182799. Molecular formula: C13H19ClN2O3. Mole weight: 286.75. Custom synthesis is available. Send your inquiries for more information. |  London |
| Melphalan Impurity 1 | Melphalan Impurity 1. Group: Pharmaceutical. Alternative Names: 4-Nitro-L-phenylalanine. CAS No. 949-99-5. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008067. Molecular formula: C9H10N2O4. Mole weight: 210.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Melphalan Impurity 2 | L-3-Nitrophenylalanine is a derivative of L-Phenylalanine, and is used in the photocleavage of polypeptide backbones. L-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded ami. Group: Pharmaceutical. Alternative Names: L-3-Nitrophenylalanine; L-3-(m-nitrophenyl)-alanine; NSC 21948. CAS No. 19883-74-0. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008058. Molecular formula: C9H10N2O4. Mole weight: 210.19. Custom synthesis is available. Send your inquiries for more information. | London |
| PX-478 dihydrochloride | PX-478 is an HIF-1alpha inhibitor and an orally active small molecule with potential antineoplastic activity. Although its mechanism of action has yet to be fully elucidated, HIF1-alpha inhibitor PX-478 appears to inhibit hypoxia-inducible factor 1-alpha (HIF1A) expression, which may result in decreased expression of HIF1A downstream target genes important to tumor growth and survival, a reduction in tumor cell proliferation, and the induction of tumor cell apoptosis. The inhibitory effect of this agent is independent of the tumor suppressor genes VHL and p53 and may be related to derangements in glucose uptake and metabolism due to inhibition of glucose transporter-1 (Glut-1). PX-478 has excellent activity against established human tumor xenografts, providing tumor regressions with prolonged growth delays which correlate positively with HIF-1 levels. PX-478 is a highly water soluble molecule, with good i.v., i.p. and p.o. antitumor activity. It is rapidly absorbed following oral and i.p. administration and gives excellent Cmax and AUC via these routes. Group: Pharmaceutical. Alternative Names: PX-478 2HCl; PX-478 hydrochloride; Melphalan N-Oxide Impurity HCl; Melphalan N-Oxide Impurity hydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, dihydrochloride; L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoamino]-, hydrochloride (1:2). CAS No. 685898-44-6. Pack Sizes: 100 mg. Product ID: B2693-459441. Molecula | London |
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