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2,4,5-Trifluoro-L-β-homophenylalanine hydrochloride is used as a reagent in the synthesis of valuable β-amylalkyl-β-amino acid enantiomers. It is also an impurity of Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: (S)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride. CAS No. 1217809-78-3. Pack Sizes: 1mg;1g;10g. Product ID: BAT-006713. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65. Custom synthesis is available. Send your inquiries for more information.
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3-Ethoxy-4-ethoxycarbonyl phenylacetic acid
An intermediate of Repaglinide. Repaglinide is an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: 3-Ethoxy-4-(ethoxycarbonyl)benzeneacetic Acid; [3-Ethoxy-4-(ethoxycarbonyl)phenyl]acetic Acid. CAS No. 99469-99-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3261. Molecular formula: C13H16O5. Mole weight: 252.27. Custom synthesis is available. Send your inquiries for more information.
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AS 1842856
AS 1842856 is a potent and selective inhibitor of Forkhead box protein O1 transcription factor (FoxO1; IC50 = 33 nM). AS 1842856 reduces glucose production in dose manner via the inhibition of glucose-6 phosphatase and phosphoenolpyruvate carboxykinase mRNA levels in a rat hepatic cell line. AS 1842856 is promisingly to be a therapy of type 2 diabetes mellitus and obesity. Uses: Potential treatment of type 2 diabetes mellitus and obesity. Group: Pharmaceutical. Alternative Names: AS1842856; AS-1842856; AS 1842856. 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. CAS No. 836620-48-5. Pack Sizes: 200 mg. Product ID: B1370-054875. Molecular formula: C18H22FN3O3. Mole weight: 347.38. Custom synthesis is available. Send your inquiries for more information.
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Boc-2-fluoro-D-β-homophenylalanine
Boc-2-fluoro-D-β-homophenylalanine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: (R)-3-((tert-butoxycarbonyl)amino)-4-(2-fluorophenyl)butanoic acid; Boc-D-β-HomoPhe(2-F)-OH; Boc-(R)-3-amino-4-(2-fluorophenyl)butyric acid. CAS No. 218608-98-1. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008041. Molecular formula: C15H20FNO4. Mole weight: 297.32. Custom synthesis is available. Send your inquiries for more information.
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Boc-3,4-difluoro-D-beta-homophenylalanine
Boc-3,4-difluoro-D-beta-homophenylalanine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: Boc-(R)-3-amino-4-(3,4-difluoro-phenyl)-butyric acid; (R)-3-((tert-butoxycarbonyl)amino)-4-(3,4-difluorophenyl)butanoic acid. CAS No. 269396-59-0. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008042. Molecular formula: C15H19F2NO4. Mole weight: 315.31. Custom synthesis is available. Send your inquiries for more information.
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Colesevelam hydrochloride
Colesevelam is a bile acid sequestrant that helps reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia, and also improve blood glucose balance in adults with type 2 diabetes mellitus. Group: Pharmaceutical. Alternative Names: CholestaGel; GT 31-104; GT 31-104HB; Welchol. CAS No. 182815-44-7. Pack Sizes: 500 mg. Product ID: B0046-086232. Molecular formula: (C13H27N)n.(C12H27ClN2)n.(C3H7N)n.(C3H5ClO)n.xHCl. Custom synthesis is available. Send your inquiries for more information.
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Exenatide acetate
Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Group: Pharmaceutical. Alternative Names: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L
Fmoc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric Acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: N-β-(9-Fluorenylmethoxycarbonyl)-2,4,5-trifluoro-D-β-homophenylalanine; (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. CAS No. 1217818-53-5. Pack Sizes: 1mg;1g;10g. Product ID: BAT-005531. Molecular formula: C25H20F3NO4. Mole weight: 455.43. Custom synthesis is available. Send your inquiries for more information.
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H-Pro-NH2
An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Group: Pharmaceutical. Alternative Names: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. CAS No. 7531-52-4. Pack Sizes: 1mg;1g;10g. Product ID: BAT-003438. Molecular formula: C5H10N2O. Mole weight: 114.1. Custom synthesis is available. Send your inquiries for more information.
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Linagliptin N-Boc Impurity
An impurity of Linagliptin. Linagliptin is a dipeptidyl peptidase-4 inhibitor with a hpyerglycemic activity. It was approved for the treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: Linagliptin Related Compound B, N-[(3R)-1-[7-(2-butyn-1-yl)-2,3,6,7-tetrahydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yl]-3-piperidinyl]-carbamic Acid 1,1-Dimethylethyl Ester. CAS No. 668273-75-4. Pack Sizes: 50 mg. Product ID: B0012-007234. Molecular formula: C30H36N8O4. Mole weight: 572.67. Custom synthesis is available. Send your inquiries for more information.
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N-acetic acid-1-amino-3-adamantanol
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Group: Pharmaceutical. Alternative Names: Vildagliptin Impurity 4; (3-hydroxyadamantan-1-ylamino)acetic acid; 2-((3-Hydroxyadamantan-1-yl)amino)acetic acid. CAS No. 1032564-18-3. Pack Sizes: 500 mg. Product ID: B2694-485169. Molecular formula: C12H19NO3. Mole weight: 225.29. Custom synthesis is available. Send your inquiries for more information.
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Perindopril Related Compound 6
An impurity of Perindopril which is used to treat patients with hypertension, diabetes mellitus type 2, coronary heart disease, chronic heart failure or stable coronary artery disease in form of perindopril arginine on the basis of a large evidence. Group: Pharmaceutical. Alternative Names: D-Oic-OH; H-D-Oic-OH; D-Octahydroindole-2-carboxylic acid. CAS No. 108507-42-2. Pack Sizes: 1mg;1g;10g. Product ID: BAT-014118. Molecular formula: C9H15NO2. Mole weight: 169.22. Custom synthesis is available. Send your inquiries for more information.
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Repaglinide Impurity E
An impurity of Repaglinide, an antidiabetic drug. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. Uses: Hypoglycemic agents. Group: Pharmaceutical. Alternative Names: 2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid; (-)-Repaglinide; AG-EE 624ZW; Repaglinide EP Impurity E; R-Repaglinide; (R)-(-)-Repaglinide. CAS No. 147852-26-4. Pack Sizes: 1 g. Product ID: B1370-263819. Molecular formula: C27H36N2O4. Mole weight: 452.6. Custom synthesis is available. Send your inquiries for more information.
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Saroglitazar
Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment of diabetic dyslipidemia and hypertriglyceridemia with Type 2 diabetes mellitus not controlled by statin therapy. Group: Pharmaceutical. Alternative Names: Lipaglyn; ZY-H1; (αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic Acid. CAS No. 495399-09-2. Pack Sizes: 10 mg. Product ID: B1370-475759. Molecular formula: C25H29NO4S. Mole weight: 439.57. Custom synthesis is available. Send your inquiries for more information.
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Sitagliptin FP Impurity E Hydrochloride
Sitagliptin EP Impurity E is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: Sitagliptin Impurity 17 HCl; Sitagliptin Acid Impurity HCl; (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride; (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride. CAS No. 1204818-19-8. Pack Sizes: 1 g. Product ID: BAT-008056. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65. Custom synthesis is available. Send your inquiries for more information.
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Sitagliptin Fumarate Adduct (Mixture of Diastereomers)
Sitagliptin Fumarate Adduct is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: Sitagliptin Tablets EP Impurity FP-A; Sitagliptin FP Impurity A; N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-L-Aspartic acid; Sitagliptin Maleate adduct. CAS No. 2088771-60-0. Pack Sizes: 50 mg. Product ID: B2694-032361. Molecular formula: C20H19F6N5O5. Mole weight: 523.39. Custom synthesis is available. Send your inquiries for more information.
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Sitagliptin Impurity 19
Sitagliptin Impurity 19 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: (R)-Sitagliptin N-Boc-Acid Impurity; (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid; Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid. CAS No. 486460-00-8. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008040. Molecular formula: C15H18F3NO4. Mole weight: 333.3. Custom synthesis is available. Send your inquiries for more information.
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Sitagliptin Impurity 21
Sitagliptin Impurity 21 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: Boc-D-β-homophenylalanine; Boc-D-β-Homophe-OH; (R)-3-(Boc-amino)-4-phenylbutyric acid; N-β-(t-Butoxycarbonyl)-D-β-homophenylalanine. CAS No. 101555-61-7. Pack Sizes: 1mg;1g;10g. Product ID: BAT-005171. Molecular formula: C15H21NO4. Mole weight: 279.33. Custom synthesis is available. Send your inquiries for more information.
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Sitagliptin Related Compound 1
Sitagliptin Related Compound 1 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid; Boc-(R)-3-amino-4-(3-fluorophenyl)-butyric acid. CAS No. 331763-66-7. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008043. Molecular formula: C15H20FNO4. Mole weight: 297.32. Custom synthesis is available. Send your inquiries for more information.
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(S)-Sitagliptin N-Boc-Acid Impurity
(S)-Sitagliptin N-Boc-Acid Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Group: Pharmaceutical. Alternative Names: Sitagliptin Impurity 41; Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid; (βS)?-β-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-2,?4,?5-trifluoro-benzenebutanoic Acid; (S)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. CAS No. 922178-94-7. Pack Sizes: 1 g. Product ID: BAT-008080. Molecular formula: C15H18F3NO4. Mole weight: 333.3. Custom synthesis is available. Send your inquiries for more information.
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Vildagliptin Impurity 3 Trifluoroacetate
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Group: Pharmaceutical. Alternative Names: Vildagliptin Carboxy Acid Metabolite Trifluoroacetate. CAS No. 565453-41-0. Pack Sizes: 10 mg. Product ID: B2694-485165. Molecular formula: C17H26N2O4. C2HF3O2. Mole weight: 436.43. Custom synthesis is available. Send your inquiries for more information.
London
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