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Product
Odanacatib Odanacatib, also known as MK-0822, is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption. Uses: For research used only. Group: Pharmaceutical. CAS No. 603139-19-1. Pack Sizes: 100 mg. Product ID: B0084-095375. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Tectorigenin Tectorigenin induced differentiation of human promyelocytic leukemia HL-60 cells to granulocytes and monocytes/macrophages, and caused apoptotic changes of DNA in the cells, as did genistein. Tectorigenin also inhibited autophosphorylation of epidermal growth factor (EGF) receptor by EGF and decreased the expression of Bcl-2 protein, with less activity than genistein. From these results, tectorigenin may be a possible therapeutic agent for leukemia. Uses: Antioxidant. Group: Pharmaceutical. CAS No. 548-77-6. Pack Sizes: 100 mg. Product ID: NP2537. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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