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MAOS is a modified Trinder's reagent used in hydrogen peroxide determination. Group: Pharmaceutical. Alternative Names: 3-[(3,5-Dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt; Sodium 3-[(3,5-dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonate; N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline Sodium Salt. CAS No. 82692-97-5. Pack Sizes: 500 mg. Product ID: B2708-099032. Molecular formula: C13H20NNaO4S. Mole weight: 309.36. Custom synthesis is available. Send your inquiries for more information.
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Afobazole
Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Group: Pharmaceutical. Alternative Names: CM346; Afobazol; Fabomotizole; CM 346; CM-346. CAS No. 173352-21-1. Pack Sizes: 5 mg. Product ID: B0084-458641. Molecular formula: C15H21N3O2S. Mole weight: 307.41. Custom synthesis is available. Send your inquiries for more information.
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Afobazole hydrochloride
Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Group: Pharmaceutical. Alternative Names: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. CAS No. 173352-39-1. Pack Sizes: 100 mg. Product ID: B2693-463567. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. Custom synthesis is available. Send your inquiries for more information.
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Desmethoxyyangonin
5,6-dehydrokawain is a natural compound found in beverages and kava. It acts as a MAO-B inhibitor. Uses: Inhibitor of mao-b. Group: Pharmaceutical. Alternative Names: Demethoxyyangonin; Desmethoxy Yangonin. CAS No. 15345-89-8. Pack Sizes: 25 mg. Product ID: NP4638. Molecular formula: C14H12O3. Mole weight: 228.247. Custom synthesis is available. Send your inquiries for more information.
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GSK-LSD1 2HCl
GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). Group: Pharmaceutical. Alternative Names: GSK LSD1 2HCl; GSK-LSD1 Dihydrochloride. CAS No. 1431368-48-7. Pack Sizes: 50 mg. Product ID: B2693-463426. Molecular formula: C14H22Cl2N2. Mole weight: 289.24. Custom synthesis is available. Send your inquiries for more information.
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Moclobemide
Moclobemide is a reversible monoamine oxidase A (MAO-A) inhibitor, displaying antidepressive activity. Group: Pharmaceutical. Alternative Names: Ro11-1163; Ro 11-1163; Ro111163; Ro-111163; Ro 111163; Moclobemide; brand name: Amira; Aurorix; Clobemix; Depnil; Manerix; 4-chloro-N-(2-morpholin-4-ylethyl)benzamide. CAS No. 71320-77-9. Pack Sizes: 100 mg. Product ID: B0084-075760. Molecular formula: C13H17ClN2O2. Mole weight: 268.74. Custom synthesis is available. Send your inquiries for more information.
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ORY-1001 dihydrochloride
ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B> 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Group: Pharmaceutical. Alternative Names: RG-6016; RG 6016; RG6016; ORY-1001 2HCl; ORY 1001 2HCl; ORY1001 2HCl; (1R,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride. CAS No. 1431326-61-2. Pack Sizes: 50 mg. Product ID: B0084-470857. Molecular formula: C15H24Cl2N2. Mole weight: 303.27. Custom synthesis is available. Send your inquiries for more information.
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Paeonol
Paeonol is the main active ingredient of Peony Bark Extract acting as a MAO-A and MAO-B inhibitor (IC50 values of 54.6 μM and 42.5 μM, respectively). It has anti-inflammatory, anti-allergic, anti-oxidation, anti-free radical and bacteriostatic properties. It can also improve skin tone and eliminate wrinkles. It can be used in skin care products and washing chemicals. Group: Pharmaceutical. Alternative Names: NSC 401442; NSC-401442; NSC401442; 1-(2-Hydroxy-4-methoxyphenyl)ethanone; 2-Hydroxy-4-methoxyacetophenone; Peony Bark Extract. CAS No. 552-41-0. Pack Sizes: 250 g. Product ID: NP4839. Molecular formula: C9H10O3. Mole weight: 166.176. Custom synthesis is available. Send your inquiries for more information.
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Rasagiline mesylate
Rasagiline (N-propargyl-1-(R)-aminoindan) is a novel, highly potent irreversible monoamine oxidase (MAO)-B inhibitor, anti-Parkinsonian drug. Uses: Neuroprotective agents. Group: Pharmaceutical. Alternative Names: TVP-1012; TVP 1012; TVP1012. CAS No. 161735-79-1. Pack Sizes: 500 mg. Product ID: NP3667. Molecular formula: C12H13N.CH4O3S. Mole weight: 267.34. Custom synthesis is available. Send your inquiries for more information.
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Rosmarinic acid
Rosmarinic acid is a naturally occurring hydroxylated compound occured in many plants. Rosmarinic acid exhibits agonist activity at GPR35 and shows antiviral, antibacterial, antiinflammatory and antioxidant activity. It is a good unctional cosmetic material. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively. Uses: Antiviral, antibacterial, antiinflammatory and antioxidant. Group: Pharmaceutical. Alternative Names: Rosemary acid; (R)-rosmarinic acid; (R,E)-3-(3,4-dihydroxyphenyl)-2-((3-(3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid; (R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4-dihydroxyphenyl)lactic acid; Benzenepropanoic acid, alpha-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxy-. CAS No. 20283-92-5. Pack Sizes: 50 g. Product ID: NP4000. Molecular formula: C18H16O8. Mole weight: 360.31. Custom synthesis is available. Send your inquiries for more information.
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Safinamide mesylate
Safinamide is a highly selective MAO-B inhibitor in rat brain mitochondria, with an IC50 of 98 nM. safinamide inhibits MAO-B in human brain with an IC50 of 9 nM. Group: Pharmaceutical. Alternative Names: PNU-151774E; (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide methanesulfonate. CAS No. 202825-46-5. Pack Sizes: 25 mg. Product ID: B2693-286699. Molecular formula: C17H19FN2O2.CH4O3S. Mole weight: 398.45. Custom synthesis is available. Send your inquiries for more information.
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Tedizolid
Torezolid is a novel oxazolidinone for gram-positive infections. It was a reversible inhibitor of human MAO-A and MAO-B. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: TR-700; TR 700; TR700; DA-7157; DA7157; DA 7157; Tedizolid; Torezolid. trade name Sivextro. CAS No. 856866-72-3. Pack Sizes: 1 g. Product ID: B0084-459901. Molecular formula: C17H15FN6O3. Mole weight: 370.34. Custom synthesis is available. Send your inquiries for more information.
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Tedizolid Phosphate
Torezolid phosphate is a novel oxazolidinone for gram-positive infections, with IC50 of 8.7 μM and 5.7 μM for monoamine oxidase (MAO)-A and MAO-B, respectively. It is commonly used for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by several Gram-positive bacteria. Uses: The treatment of acute bacterial skin and skin structure infections (absssi). Group: Pharmaceutical. Alternative Names: TR-701FA; Torezolid phosphate; Sivextro; Tedizolid (phosphate); UNII-O7DRJ6R4DW. CAS No. 856867-55-5. Pack Sizes: 250 mg. Product ID: B0084-465276. Molecular formula: C17H16FN6O6P. Mole weight: 450.32. Custom synthesis is available. Send your inquiries for more information.
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