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| Product | Description | |
|---|---|---|
| LY2784544 | LY2784544 is a potent and selective JAK2 inhibitor (IC50 = 3 nM), and exhibits less potency against JAK3 (IC50 =48 nM). LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC50 = 20 and 55 nM, respectively). It reduces JAK2V617F tumor cell burden with no effect on erythroid progenitor cells. Group: Pharmaceutical. Alternative Names: Gandotinib; LY-2784544; 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine. CAS No. 1229236-86-5. Pack Sizes: 25 mg. Product ID: B0084-286443. Molecular formula: C23H25ClFN7O. Mole weight: 469.949. Custom synthesis is available. Send your inquiries for more information. |  London |
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